HGH1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description HGH1 cochaperone (NCBI Entrez Gene Database, 51236)
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Genes

368 genes differentially expressed following the HGH1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CDCP2 CUB domain containing protein 2 2.46691
AGBL4 ATP/GTP binding protein-like 4 2.46691
ARGFX arginine-fifty homeobox 2.46691
FMO1 flavin containing monooxygenase 1 2.46691
PLIN1 perilipin 1 2.46691
PROX2 prospero homeobox 2 2.46691
RBM20 RNA binding motif protein 20 2.46691
ARL5C ADP-ribosylation factor-like 5C 2.46691
CD8B CD8b molecule 2.46691
FAM107A family with sequence similarity 107, member A 2.46691
RNF113B ring finger protein 113B 2.46691
NIPAL4 NIPA-like domain containing 4 2.46691
CD53 CD53 molecule 2.46691
GLIPR1L2 GLI pathogenesis-related 1 like 2 2.46691
IRGM immunity-related GTPase family, M 2.46691
FZD1 frizzled class receptor 1 2.46691
RERGL RERG/RAS-like 2.46691
CLCF1 cardiotrophin-like cytokine factor 1 2.46691
BTN3A3 butyrophilin, subfamily 3, member A3 2.46691
PLA1A phospholipase A1 member A 2.46691
GJA3 gap junction protein, alpha 3, 46kDa 2.46691
SPINT4 serine peptidase inhibitor, Kunitz type 4 2.46691
PLA2G2D phospholipase A2, group IID 2.46691
KCNK9 potassium channel, two pore domain subfamily K, member 9 2.46691
CD274 CD274 molecule 2.46691
SCARA5 scavenger receptor class A, member 5 2.46691
ARHGAP36 Rho GTPase activating protein 36 2.41911
GSTM3 glutathione S-transferase mu 3 (brain) 2.41911
NAPSA napsin A aspartic peptidase 2.41911
LRRD1 leucine-rich repeats and death domain containing 1 2.41911
GLYAT glycine-N-acyltransferase 2.41911
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 2.41911
GPR52 G protein-coupled receptor 52 2.41911
COLEC10 collectin sub-family member 10 (C-type lectin) 2.41911
PRICKLE4 prickle homolog 4 (Drosophila) 2.41911
ZNF503 zinc finger protein 503 2.41911
TXNDC8 thioredoxin domain containing 8 (spermatozoa) 2.41911
HCRTR1 hypocretin (orexin) receptor 1 2.41911
FABP1 fatty acid binding protein 1, liver 2.41911
GNLY granulysin 2.41911
EPHX4 epoxide hydrolase 4 2.41911
TYRP1 tyrosinase-related protein 1 2.41911
ZNF699 zinc finger protein 699 2.41911
ACOT12 acyl-CoA thioesterase 12 2.41911
CPLX4 complexin 4 2.41911
TMC2 transmembrane channel-like 2 2.41911
GCSAM germinal center-associated, signaling and motility 2.41911
SPTSSA serine palmitoyltransferase, small subunit A 2.41911
NWD2 NACHT and WD repeat domain containing 2 2.41911
RNASE6 ribonuclease, RNase A family, k6 2.41911
SMCO3 single-pass membrane protein with coiled-coil domains 3 2.41911
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.41911
CCDC38 coiled-coil domain containing 38 2.41911
CA11 carbonic anhydrase XI 2.41911
GDNF glial cell derived neurotrophic factor 2.41911
ASB10 ankyrin repeat and SOCS box containing 10 2.41911
RSPO1 R-spondin 1 2.41911
GALP galanin-like peptide 2.41911
SHCBP1L SHC SH2-domain binding protein 1-like 2.41911
MYOM2 myomesin 2 2.41911
GADL1 glutamate decarboxylase-like 1 2.41911
GMFB glia maturation factor, beta 2.41911
MS4A14 membrane-spanning 4-domains, subfamily A, member 14 2.41911
PER2 period circadian clock 2 2.41911
TMEM184A transmembrane protein 184A 2.41911
SPATA31G1 SPATA31 subfamily G member 1 2.41911
YIPF7 Yip1 domain family, member 7 2.41911
ROPN1L rhophilin associated tail protein 1-like 2.41911
AVPR1B arginine vasopressin receptor 1B 2.41911
POM121L2 POM121 transmembrane nucleoporin-like 2 2.41911
SRGN serglycin 2.41911
OR6F1 olfactory receptor, family 6, subfamily F, member 1 2.41911
OR1C1 olfactory receptor, family 1, subfamily C, member 1 2.41911
ASB9 ankyrin repeat and SOCS box containing 9 2.41911
BDKRB1 bradykinin receptor B1 2.41911
FOXC1 forkhead box C1 2.41911
OTOF otoferlin 2.41911
HTD2 hydroxyacyl-thioester dehydratase type 2 2.41911
EPCIP exosomal polycystin 1 interacting protein 2.41911
LRRC8C-DT LRRC8C divergent transcript 2.41911
SPMIP3 sperm microtubule inner protein 3 2.41911
C17ORF113 chromosome 17 open reading frame 113 2.41911
LOC122526780 uncharacterized LOC122526780 2.41911
H2BW2 H2B.W histone 2 2.41911
ATP5MGL ATP synthase membrane subunit g like 2.41911
GPRASP3 G protein-coupled receptor associated sorting protein family member 3 2.41911
CCN5 cellular communication network factor 5 2.41911
SLURP2 secreted LY6/PLAUR domain containing 2 2.41911
TOP1 topoisomerase (DNA) I 2.41911
GOLM1 golgi membrane protein 1 2.41911
OR52E5 olfactory receptor, family 52, subfamily E, member 5 2.41911
PRB4 proline-rich protein BstNI subfamily 4 2.41911
KLHL33 kelch-like family member 33 2.41911
DTHD1 death domain containing 1 2.41911
PCDHA3 protocadherin alpha 3 2.41911
LIPJ lipase, family member J 2.41911
ISM2 isthmin 2 2.41911
FAM13B family with sequence similarity 13, member B 2.41911
PDILT protein disulfide isomerase-like, testis expressed 2.41911
COL19A1 collagen, type XIX, alpha 1 2.41911
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 2.41911
CFAP99 cilia and flagella associated protein 99 2.41911
CHRD chordin 2.41911
TXNRD3 thioredoxin reductase 3 2.41911
LTF lactotransferrin 2.41911
SAMD11 sterile alpha motif domain containing 11 2.41911
S100G S100 calcium binding protein G 2.41911
AR androgen receptor 2.41911
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 2.41911
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 2.41911
TLR8 toll-like receptor 8 2.41911
ULBP1 UL16 binding protein 1 2.41911
VSX2 visual system homeobox 2 2.41911
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 2.41911
AMPD1 adenosine monophosphate deaminase 1 2.41911
TRIM29 tripartite motif containing 29 2.41911
RETNLB resistin like beta 2.41911
CYSLTR1 cysteinyl leukotriene receptor 1 2.41911
NOX1 NADPH oxidase 1 2.41911
SALL2 spalt-like transcription factor 2 2.41911
BPIFB1 BPI fold containing family B, member 1 2.41911
GOLGA6D golgin A6 family, member D 2.41911
HOXD1 homeobox D1 2.41911
CDH19 cadherin 19, type 2 2.41911
TCP11X2 t-complex 11 family, X-linked 2 2.41911
CBX2 chromobox homolog 2 2.41911
PCDHGA3 protocadherin gamma subfamily A, 3 2.41911
DLL1 delta-like 1 (Drosophila) 2.41911
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13 2.41911
OR56A4 olfactory receptor, family 56, subfamily A, member 4 2.41911
ZNF679 zinc finger protein 679 2.41911
HSPB9 heat shock protein, alpha-crystallin-related, B9 2.41911
MAGEB17 melanoma antigen family B17 2.41911
KRT17 keratin 17, type I 2.41911
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 2.41911
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 2.41911
NEK9 NIMA-related kinase 9 2.41911
TRIM7 tripartite motif containing 7 2.41911
KCNK4 potassium channel, two pore domain subfamily K, member 4 2.41911
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 2.41911
RGS13 regulator of G-protein signaling 13 2.41911
FOXE3 forkhead box E3 2.41911
TEKT5 tektin 5 2.41911
CHSY1 chondroitin sulfate synthase 1 2.41911
NKX6-1 NK6 homeobox 1 2.41911
SPTA1 spectrin, alpha, erythrocytic 1 2.41911
C11ORF42 chromosome 11 open reading frame 42 2.41911
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 2.41911
GAS2L2 growth arrest-specific 2 like 2 2.41911
CNR2 cannabinoid receptor 2 (macrophage) 2.41911
LMX1A LIM homeobox transcription factor 1, alpha 2.41911
CNGB1 cyclic nucleotide gated channel beta 1 2.41911
NPY2R neuropeptide Y receptor Y2 2.41911
SLC17A2 solute carrier family 17, member 2 2.41911
ZNF831 zinc finger protein 831 2.41911
MOBP myelin-associated oligodendrocyte basic protein 2.41911
PSG8 pregnancy specific beta-1-glycoprotein 8 2.41911
SCN1A sodium channel, voltage gated, type I alpha subunit 2.41911
PCDHA10 protocadherin alpha 10 2.41911
TEX12 testis expressed 12 2.41911
FAM135B family with sequence similarity 135, member B 2.41911
UBTF upstream binding transcription factor, RNA polymerase I 2.41911
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 2.41911
SPEF1 sperm flagellar 1 2.41911
SYNGR4 synaptogyrin 4 2.41911
IP6K3 inositol hexakisphosphate kinase 3 2.41911
OTOP2 otopetrin 2 2.41911
NT5C1B 5'-nucleotidase, cytosolic IB 2.41911
TAGAP T-cell activation RhoGTPase activating protein 2.41911
OR52N2 olfactory receptor, family 52, subfamily N, member 2 2.41911
ECM1 extracellular matrix protein 1 2.41911
SSX3 synovial sarcoma, X breakpoint 3 2.41911
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 2.41911
VTCN1 V-set domain containing T cell activation inhibitor 1 2.41911
XCR1 chemokine (C motif) receptor 1 2.41911
IFNK interferon, kappa 2.41911
JMY junction mediating and regulatory protein, p53 cofactor 2.41911
MMP1 matrix metallopeptidase 1 2.41911
LRRC74A leucine rich repeat containing 74A 2.41911
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 2.41911
CLCA4 chloride channel accessory 4 2.41911
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 2.41911
TICAM1 toll-like receptor adaptor molecule 1 2.41911
IL37 interleukin 37 2.41911
SCN3A sodium channel, voltage gated, type III alpha subunit 2.41911
OR6B1 olfactory receptor, family 6, subfamily B, member 1 2.41911
IRX1 iroquois homeobox 1 2.41911
TBC1D21 TBC1 domain family, member 21 2.41911
TBC1D28 TBC1 domain family, member 28 2.41911
OR1G1 olfactory receptor, family 1, subfamily G, member 1 2.41911
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 2.41911
APOH apolipoprotein H (beta-2-glycoprotein I) 2.41911
DCAF17 DDB1 and CUL4 associated factor 17 2.41911
DCAF10 DDB1 and CUL4 associated factor 10 2.41911
IL33 interleukin 33 2.41911
NUTM2B NUT family member 2B 2.41911
PAGE2B P antigen family, member 2B 2.41911
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 2.41404
NMUR2 neuromedin U receptor 2 2.41404
FH fumarate hydratase 2.41404
ASB12 ankyrin repeat and SOCS box containing 12 2.41404
PGBD4 piggyBac transposable element derived 4 2.38041
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 2.38041
FGF8 fibroblast growth factor 8 (androgen-induced) 2.38041
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.38041
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 2.38041
TMC3 transmembrane channel-like 3 2.38041
TMC8 transmembrane channel-like 8 2.38041
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 2.38041
IL10RB interleukin 10 receptor, beta 2.38026
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 2.38026
MAP2K3 mitogen-activated protein kinase kinase 3 2.35867
PIGU phosphatidylinositol glycan anchor biosynthesis, class U 2.32336
ZNF383 zinc finger protein 383 2.31671
MPZL1 myelin protein zero-like 1 2.27051
CCDC169 coiled-coil domain containing 169 2.26657
ZNF280C zinc finger protein 280C 2.22804
SFMBT1 Scm-like with four mbt domains 1 2.22804
SBNO1 strawberry notch homolog 1 (Drosophila) 2.19185
LMF1 lipase maturation factor 1 2.1893
DTNB dystrobrevin, beta 2.18536
SF3A1 splicing factor 3a, subunit 1, 120kDa 2.17012
ZNF737 zinc finger protein 737 2.17012
SEPTIN5 septin 5 2.1639
PDE4DIP phosphodiesterase 4D interacting protein 2.1639
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.1639
SNX10 sorting nexin 10 2.15723
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) 2.149
LZTS2 leucine zipper, putative tumor suppressor 2 2.14888
AAK1 AP2 associated kinase 1 2.14888
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 2.14137
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 2.12677
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 2.12582
MAP1B microtubule-associated protein 1B 2.12479
DIAPH1 diaphanous-related formin 1 2.12449
SLC26A2 solute carrier family 26 (anion exchanger), member 2 2.11486
SHISA5 shisa family member 5 2.1121
LIPT2 lipoyl(octanoyl) transferase 2 (putative) 2.1121
WDR73 WD repeat domain 73 2.10474
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 2.09756
MON1A MON1 secretory trafficking family member A 2.09304
ARHGAP18 Rho GTPase activating protein 18 2.07723
NAA80 N-alpha-acetyltransferase 80, NatH catalytic subunit 2.07356
TFDP1 transcription factor Dp-1 2.05118
HAGHL hydroxyacylglutathione hydrolase-like 2.05118
TMEM245 transmembrane protein 245 2.04066
TRAFD1 TRAF-type zinc finger domain containing 1 2.02323
PSTK phosphoseryl-tRNA kinase 2.02323
DPYSL2 dihydropyrimidinase-like 2 2.02323
MRPL2 mitochondrial ribosomal protein L2 2.015
CNOT2 CCR4-NOT transcription complex, subunit 2 2.0108
RFT1 RFT1 homolog (S. cerevisiae) 2.00939

decreased expression

Symbol Name Standardized Value
SYT6 synaptotagmin VI -2.46691
BATF3 basic leucine zipper transcription factor, ATF-like 3 -2.46691
ARHGEF33 Rho guanine nucleotide exchange factor (GEF) 33 -2.46691
HTATSF1 HIV-1 Tat specific factor 1 -2.41911
OPRD1 opioid receptor, delta 1 -2.41911
GFOD1 glucose-fructose oxidoreductase domain containing 1 -2.41911
DUSP18 dual specificity phosphatase 18 -2.41911
ZNF765 zinc finger protein 765 -2.41911
DGKZ diacylglycerol kinase, zeta -2.41911
SDC1 syndecan 1 -2.41911
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -2.41911
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 -2.41911
SLC35G2 solute carrier family 35, member G2 -2.41911
TP53RK TP53 regulating kinase -2.41911
CEP162 centrosomal protein 162kDa -2.41911
GPX4 glutathione peroxidase 4 -2.41911
STAC3 SH3 and cysteine rich domain 3 -2.41911
CDKL4 cyclin-dependent kinase-like 4 -2.41911
THOC6 THO complex 6 -2.41911
ZAN zonadhesin (gene/pseudogene) -2.41911
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -2.41911
ZNF174 zinc finger protein 174 -2.41911
CLIC5 chloride intracellular channel 5 -2.41911
NID2 nidogen 2 (osteonidogen) -2.41911
CARHSP1 calcium regulated heat stable protein 1, 24kDa -2.41911
INSR insulin receptor -2.41911
TSPYL2 TSPY-like 2 -2.41911
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.41911
RHBDD2 rhomboid domain containing 2 -2.41404
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 -2.41404
WDR54 WD repeat domain 54 -2.41404
DPPA3 developmental pluripotency associated 3 -2.41404
GPANK1 G patch domain and ankyrin repeats 1 -2.41404
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -2.41404
GALR3 galanin receptor 3 -2.41404
ETV2 ets variant 2 -2.41404
EPHA3 EPH receptor A3 -2.41404
TLDC2 TBC/LysM-associated domain containing 2 -2.41404
ALKAL1 ALK and LTK ligand 1 -2.41404
SLC46A2 solute carrier family 46, member 2 -2.41404
CBLIF cobalamin binding intrinsic factor -2.41404
BTG4 B-cell translocation gene 4 -2.41404
SYT5 synaptotagmin V -2.41404
RAB36 RAB36, member RAS oncogene family -2.41404
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 -2.41404
MYH7B myosin, heavy chain 7B, cardiac muscle, beta -2.41404
LOC114841035 uncharacterized LOC114841035 -2.41404
NXPE1 neurexophilin and PC-esterase domain family, member 1 -2.41404
CAPN14 calpain 14 -2.41404
WEE2 WEE1 homolog 2 (S. pombe) -2.41404
ZNF492 zinc finger protein 492 -2.41404
KLK11 kallikrein-related peptidase 11 -2.41404
C11ORF16 chromosome 11 open reading frame 16 -2.41404
EIF3CL eukaryotic translation initiation factor 3, subunit C-like -2.41404
TGM2 transglutaminase 2 -2.41404
DRD3 dopamine receptor D3 -2.41404
CDC20B cell division cycle 20B -2.41404
SDSL serine dehydratase-like -2.41404
NUTM1 NUT midline carcinoma, family member 1 -2.41404
GPRC5A G protein-coupled receptor, class C, group 5, member A -2.41404
DCAF12L2 DDB1 and CUL4 associated factor 12-like 2 -2.41404
ACSM1 acyl-CoA synthetase medium-chain family member 1 -2.41404
RUFY4 RUN and FYVE domain containing 4 -2.41404
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 -2.41404
TMEM150B transmembrane protein 150B -2.41404
RTN4RL1 reticulon 4 receptor-like 1 -2.41404
LOXL4 lysyl oxidase-like 4 -2.41404
AOC2 amine oxidase, copper containing 2 (retina-specific) -2.41211
GALNT16 polypeptide N-acetylgalactosaminyltransferase 16 -2.40961
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.39431
FAM219A family with sequence similarity 219, member A -2.38026
REXO2 RNA exonuclease 2 -2.33436
FAM111B family with sequence similarity 111, member B -2.33436
EIF4A2 eukaryotic translation initiation factor 4A2 -2.32761
RUNDC1 RUN domain containing 1 -2.28158
GNMT glycine N-methyltransferase -2.28085
ZNF841 zinc finger protein 841 -2.28085
FOXK1 forkhead box K1 -2.27026
TERF2IP telomeric repeat binding factor 2, interacting protein -2.26265
TNRC18 trinucleotide repeat containing 18 -2.26265
NPDC1 neural proliferation, differentiation and control, 1 -2.24346
KRT18 keratin 18, type I -2.23008
MICU2 mitochondrial calcium uptake 2 -2.22802
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -2.20239
CCDC191 coiled-coil domain containing 191 -2.18023
PARP11 poly (ADP-ribose) polymerase family, member 11 -2.17882
LGALS9 lectin, galactoside-binding, soluble, 9 -2.17012
CALY calcyon neuron-specific vesicular protein -2.17012
MAP6 microtubule-associated protein 6 -2.17012
CHADL chondroadherin-like -2.17012
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.1639
RAB11B RAB11B, member RAS oncogene family -2.1639
MYL12B myosin, light chain 12B, regulatory -2.16205
GUSB glucuronidase, beta -2.14888
TMEM220 transmembrane protein 220 -2.14888
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 -2.14888
B3GAT2 beta-1,3-glucuronyltransferase 2 -2.14137
WRN Werner syndrome, RecQ helicase-like -2.14137
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -2.13549
SERF2 small EDRK-rich factor 2 -2.13295
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein -2.13272
TSC2 tuberous sclerosis 2 -2.11582
ABTB3 ankyrin repeat and BTB domain containing 3 -2.1121
ZNF658 zinc finger protein 658 -2.09756
DTX4 deltex 4, E3 ubiquitin ligase -2.08645
AP4S1 adaptor-related protein complex 4, sigma 1 subunit -2.07619
NENF neudesin neurotrophic factor -2.07362
LRRC57 leucine rich repeat containing 57 -2.07362
GPR3 G protein-coupled receptor 3 -2.05118
MSH3 mutS homolog 3 -2.0482
DCAF13 DDB1 and CUL4 associated factor 13 -2.04637
TMEM182 transmembrane protein 182 -2.04284
TACR3 tachykinin receptor 3 -2.04284
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) -2.03457
FAM194C family with sequence similarity 149 member C -2.02969
MRC2 mannose receptor, C type 2 -2.00667