| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)|This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011] (NCBI Entrez Gene Database, 3091) |
| External Link | https://ncbi.nlm.nih.gov/gene/3091 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the HIF1A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| WDR61 | WD repeat domain 61 | 0.00748285 |
| EAF2 | ELL associated factor 2 | 0.00745294 |
| XIC | X chromosome inactivation center | 0.00724817 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00686465 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00670909 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 0.00667111 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0064893 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00634371 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.00624844 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00622617 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00607851 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.00597519 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00589471 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00582097 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00571487 |
| FABP1 | fatty acid binding protein 1, liver | 0.00555731 |
| KLK6 | kallikrein-related peptidase 6 | 0.00548627 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00543534 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00541997 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00529078 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0052737 |
| CAB39 | calcium binding protein 39 | 0.00523 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00518067 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 0.00511031 |
| ARG2 | arginase 2 | 0.00509149 |
| CD9 | CD9 molecule | 0.00498659 |
| PLK1 | polo-like kinase 1 | 0.00496051 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00494762 |
| CHN2 | chimerin 2 | 0.00488972 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00481503 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.0047713 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00464854 |
| LSM1 | LSM1, U6 small nuclear RNA associated | 0.00464149 |
| MX1 | MX dynamin-like GTPase 1 | 0.00457231 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | 0.00456569 |
| BAG3 | BCL2-associated athanogene 3 | 0.00452729 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00447445 |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.00446568 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.00446224 |
| DPEP1 | dipeptidase 1 (renal) | 0.00444661 |
| NPY | neuropeptide Y | 0.00444634 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00442894 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.00440881 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.00440655 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00436982 |
| KIF20A | kinesin family member 20A | 0.00427695 |
| MMP10 | matrix metallopeptidase 10 | 0.00426991 |
| SPPL2B | signal peptide peptidase like 2B | 0.00426163 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00423831 |
| LYPLA1 | lysophospholipase I | 0.00423666 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 0.00423645 |
| PDLIM3 | PDZ and LIM domain 3 | 0.00420677 |
| ADI1 | acireductone dioxygenase 1 | 0.00419791 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00419183 |
| MGP | matrix Gla protein | 0.0041838 |
| PLAT | plasminogen activator, tissue | 0.00416377 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00416212 |
| NVL | nuclear VCP-like | 0.00415049 |
| HAT1 | histone acetyltransferase 1 | 0.00413266 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.00412543 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00410538 |
| SELENOW | selenoprotein W | 0.00408149 |
| PCTP | phosphatidylcholine transfer protein | 0.00407455 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00404983 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 | 0.00404915 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00404078 |
| TSPAN1 | tetraspanin 1 | 0.00402156 |
| PMM2 | phosphomannomutase 2 | 0.0040154 |
| C7 | complement component 7 | 0.00400565 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00400124 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00399905 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.0039932 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00399249 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.00399187 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | 0.00399119 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00397693 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00395826 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.00395721 |
| SAR1B | secretion associated, Ras related GTPase 1B | 0.00389861 |
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.00389664 |
| COMMD8 | COMM domain containing 8 | 0.00386235 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.00386149 |
| PCLAF | PCNA clamp associated factor | 0.00385385 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.00384642 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00384512 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00384243 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | 0.00382715 |
| METTL5 | methyltransferase like 5 | 0.00379782 |
| GPX7 | glutathione peroxidase 7 | 0.00377631 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00375731 |
| NFU1 | NFU1 iron-sulfur cluster scaffold | 0.00375644 |
| UBB | ubiquitin B | 0.00373892 |
| XPO7 | exportin 7 | 0.00373652 |
| RTCB | RNA 2',3'-cyclic phosphate and 5'-OH ligase | 0.00372938 |
| FCRL2 | Fc receptor-like 2 | 0.00372428 |
| YME1L1 | YME1-like 1 ATPase | 0.0037201 |
| DCK | deoxycytidine kinase | 0.00370156 |
| DEFB1 | defensin, beta 1 | 0.00370001 |
| DCTN3 | dynactin 3 (p22) | 0.00366693 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00366498 |
| MCM6 | minichromosome maintenance complex component 6 | 0.00366219 |
| RNF43 | ring finger protein 43 | 0.00365677 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00364514 |
| ORC4 | origin recognition complex, subunit 4 | 0.00363579 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00362957 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00360873 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00359311 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.00358972 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00357572 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.00355404 |
| RPA3 | replication protein A3, 14kDa | 0.00355296 |
| RHOB | ras homolog family member B | 0.00354749 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00354563 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 0.00353536 |
| PLN | phospholamban | 0.00351196 |
| TST | thiosulfate sulfurtransferase (rhodanese) | 0.00350716 |
| CDC42 | cell division cycle 42 | 0.00350576 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00349207 |
| VBP1 | von Hippel-Lindau binding protein 1 | 0.00348219 |
| NPR1 | natriuretic peptide receptor 1 | 0.00347826 |
| OIP5 | Opa interacting protein 5 | 0.0034697 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00345586 |
| STOML2 | stomatin (EPB72)-like 2 | 0.00344926 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.0034441 |
| SMAD6 | SMAD family member 6 | 0.00343118 |
| EXOSC5 | exosome component 5 | 0.003431 |
| SNRPD3 | small nuclear ribonucleoprotein D3 polypeptide 18kDa | 0.00342 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00341064 |
| BTG2 | BTG family, member 2 | 0.00339864 |
| TMEM100 | transmembrane protein 100 | 0.0033964 |
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 | 0.00339639 |
| EPHB2 | EPH receptor B2 | 0.00339215 |
| ADIRF | adipogenesis regulatory factor | 0.00338911 |
| PAK1IP1 | PAK1 interacting protein 1 | 0.00338665 |
| FERMT1 | fermitin family member 1 | 0.00338556 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00338526 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00337794 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00337488 |
| CACYBP | calcyclin binding protein | 0.00336238 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 0.00335502 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00335139 |
| HIKESHI | heat shock protein nuclear import factor hikeshi | 0.00333969 |
| SMS | spermine synthase | 0.00332724 |
| TMEM14B | transmembrane protein 14B | 0.00332469 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | 0.00331002 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.00329365 |
| DES | desmin | 0.00329137 |
| CCL17 | chemokine (C-C motif) ligand 17 | 0.00328671 |
| CIT | citron rho-interacting serine/threonine kinase | 0.00328665 |
| REG3A | regenerating islet-derived 3 alpha | 0.0032687 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00325963 |
| IRF7 | interferon regulatory factor 7 | 0.0032557 |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.00325336 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) | 0.00324886 |
| DENND1B | DENN/MADD domain containing 1B | 0.00324283 |
| ATP10B | ATPase, class V, type 10B | 0.00323874 |
| MZT2A | mitotic spindle organizing protein 2A | 0.00323624 |
| ACOT7 | acyl-CoA thioesterase 7 | 0.00323227 |
| NELL1 | NEL-like 1 (chicken) | 0.00323154 |
| ZNF593 | zinc finger protein 593 | 0.00323118 |
| SYT1 | synaptotagmin I | 0.00322709 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 0.00322081 |
| DUOX2 | dual oxidase 2 | 0.00321726 |
| MRPL17 | mitochondrial ribosomal protein L17 | 0.00321372 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.00320868 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00318725 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | 0.00317752 |
| MRPL33 | mitochondrial ribosomal protein L33 | 0.00317461 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | 0.00316548 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase | 0.00316365 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.00315887 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | 0.00315689 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.00315092 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00314867 |
| MMP11 | matrix metallopeptidase 11 | 0.00314657 |
| PRKCA | protein kinase C, alpha | 0.00314268 |
| ADRA2A | adrenoceptor alpha 2A | 0.00313532 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00311202 |
| ATP9A | ATPase, class II, type 9A | 0.0031103 |
| AOC1 | amine oxidase, copper containing 1 | 0.0031037 |
| LSM8 | LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00310291 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.00309701 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00309647 |
| VPREB3 | pre-B lymphocyte 3 | 0.0030905 |
| OAT | ornithine aminotransferase | 0.00309045 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F | 0.00304937 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00304445 |
| C1QBP | complement component 1, q subcomponent binding protein | 0.0030439 |
| DPYS | dihydropyrimidinase | 0.00304094 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00303056 |
| PSMA5 | proteasome (prosome, macropain) subunit, alpha type, 5 | 0.00303054 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.00303042 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | 0.00302413 |
| SCRG1 | stimulator of chondrogenesis 1 | 0.00302166 |
| ICAM2 | intercellular adhesion molecule 2 | 0.00300916 |
| CCNC | cyclin C | 0.00300473 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00300409 |
| NRIP3 | nuclear receptor interacting protein 3 | 0.00299748 |
| BHMT | betaine--homocysteine S-methyltransferase | 0.00299695 |
| TIMM23 | translocase of inner mitochondrial membrane 23 homolog (yeast) | 0.00299391 |
| COA3 | cytochrome c oxidase assembly factor 3 | 0.00299256 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.00298964 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00298766 |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F | 0.00298424 |
| RAB21 | RAB21, member RAS oncogene family | 0.00298384 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 0.00298337 |
| SNX11 | sorting nexin 11 | 0.00298324 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00298014 |
| MRPL18 | mitochondrial ribosomal protein L18 | 0.00296386 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 | 0.00295839 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00294213 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00294093 |
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 0.00293675 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 0.00292694 |
| TOR1A | torsin family 1, member A (torsin A) | 0.00292296 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00292111 |
| SORBS3 | sorbin and SH3 domain containing 3 | 0.00290831 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.00290419 |
| EREG | epiregulin | 0.00289645 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00289622 |
| HSPE1 | heat shock 10kDa protein 1 | 0.00289167 |
| CAST | calpastatin | 0.00288798 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0028855 |
| TLR4 | toll-like receptor 4 | 0.00287917 |
| MT1E | metallothionein 1E | 0.0028699 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00286413 |
| CDC123 | cell division cycle 123 | 0.00286016 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00285791 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00285394 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.00284941 |
| TCL1A | T-cell leukemia/lymphoma 1A | 0.00284893 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0028471 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | 0.00284637 |
| WDR76 | WD repeat domain 76 | 0.00284509 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | 0.00283967 |
| HOXC6 | homeobox C6 | 0.00283628 |
| RAB33A | RAB33A, member RAS oncogene family | 0.0028341 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 0.00283242 |
| LYZ | lysozyme | 0.0028314 |
| FNTA | farnesyltransferase, CAAX box, alpha | 0.0028297 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00282759 |
| MRPL58 | mitochondrial ribosomal protein L58 | 0.00282409 |
| NES | nestin | 0.00282356 |
| ADSL | adenylosuccinate lyase | 0.00281362 |
| PDCD10 | programmed cell death 10 | 0.00280563 |
| NAAA | N-acylethanolamine acid amidase | 0.00280404 |
| CD27 | CD27 molecule | 0.00280263 |
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | 0.00280252 |
| SGMS1 | sphingomyelin synthase 1 | 0.00279278 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LTF | lactotransferrin | -0.0121317 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.00881389 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00830016 |
| MLPH | melanophilin | -0.00796428 |
| STK10 | serine/threonine kinase 10 | -0.00752036 |
| DSP | desmoplakin | -0.00746484 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.00735471 |
| RRAGD | Ras-related GTP binding D | -0.00724868 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00710254 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00695417 |
| PLPP3 | phospholipid phosphatase 3 | -0.00686905 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00664198 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0066338 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00638368 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00630909 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00630699 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00628071 |
| LOX | lysyl oxidase | -0.00627712 |
| PIP | prolactin-induced protein | -0.00623516 |
| G0S2 | G0/G1 switch 2 | -0.00622339 |
| HK2 | hexokinase 2 | -0.00617744 |
| ADM | adrenomedullin | -0.00613144 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00606847 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00584872 |
| ZNF395 | zinc finger protein 395 | -0.00581595 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00579878 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0057703 |
| TMEM45A | transmembrane protein 45A | -0.00576833 |
| GPM6B | glycoprotein M6B | -0.00574195 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.0056184 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00559879 |
| CD99 | CD99 molecule | -0.00553943 |
| PERP | PERP, TP53 apoptosis effector | -0.00552872 |
| MAGEA3 | melanoma antigen family A3 | -0.00551236 |
| KRT7 | keratin 7, type II | -0.0055028 |
| GOLGA8A | golgin A8 family, member A | -0.005441 |
| C3 | complement component 3 | -0.00542267 |
| CP | ceruloplasmin (ferroxidase) | -0.00541205 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.00535674 |
| STC2 | stanniocalcin 2 | -0.00530251 |
| GOLGA8H | golgin A8 family, member H | -0.00524146 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00520657 |
| MARCKSL1 | MARCKS-like 1 | -0.00520138 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00518742 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00518445 |
| PFKL | phosphofructokinase, liver | -0.00518444 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00516104 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00515176 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00511684 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00511472 |
| FGG | fibrinogen gamma chain | -0.00508824 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00507113 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.00504838 |
| PLXND1 | plexin D1 | -0.00501717 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00501295 |
| INHBB | inhibin, beta B | -0.00500813 |
| IRS2 | insulin receptor substrate 2 | -0.00498732 |
| TRAF3IP2 | TRAF3 interacting protein 2 | -0.00497095 |
| GPI | glucose-6-phosphate isomerase | -0.00496517 |
| KRT14 | keratin 14, type I | -0.00496317 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00493875 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00491824 |
| TFF1 | trefoil factor 1 | -0.00491251 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.0049094 |
| FOXN3 | forkhead box N3 | -0.00490576 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00486339 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00483901 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0048285 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.00481841 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00480028 |
| KRT19 | keratin 19, type I | -0.00479251 |
| MTA1 | metastasis associated 1 | -0.00474635 |
| FPR1 | formyl peptide receptor 1 | -0.00472951 |
| GNAS | GNAS complex locus | -0.00471098 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.00468409 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.0046735 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00465331 |
| FCGBP | Fc fragment of IgG binding protein | -0.00454712 |
| OPN3 | opsin 3 | -0.004546 |
| APMAP | adipocyte plasma membrane associated protein | -0.00454089 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00452635 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.00450002 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.00448257 |
| ACKR3 | atypical chemokine receptor 3 | -0.00448151 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.00443893 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.00443517 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.00443077 |
| MFAP5 | microfibrillar associated protein 5 | -0.00442176 |
| S100P | S100 calcium binding protein P | -0.00440649 |
| AGR2 | anterior gradient 2 | -0.0043995 |
| PLXNC1 | plexin C1 | -0.00437104 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -0.00436998 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00436869 |
| RTN3 | reticulon 3 | -0.00435949 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00432415 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.00429559 |
| CD14 | CD14 molecule | -0.00428762 |
| RAB8A | RAB8A, member RAS oncogene family | -0.00426749 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -0.00424708 |
| ASS1 | argininosuccinate synthase 1 | -0.00423413 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00423183 |
| WLS | wntless Wnt ligand secretion mediator | -0.0042174 |
| SLC46A3 | solute carrier family 46, member 3 | -0.00420093 |
| IL32 | interleukin 32 | -0.00418094 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00417247 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00416183 |
| S100A8 | S100 calcium binding protein A8 | -0.00415667 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00415104 |
| CHI3L2 | chitinase 3-like 2 | -0.00414143 |
| ORM1 | orosomucoid 1 | -0.00413999 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00413813 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00412172 |
| SNAI2 | snail family zinc finger 2 | -0.00411186 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00410102 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00409481 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | -0.00408168 |
| NDRG1 | N-myc downstream regulated 1 | -0.004061 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00405525 |
| CD164 | CD164 molecule, sialomucin | -0.00404154 |
| NID2 | nidogen 2 (osteonidogen) | -0.00403909 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.00402683 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00402063 |
| PKP2 | plakophilin 2 | -0.00398027 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00395263 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | -0.00394754 |
| GCH1 | GTP cyclohydrolase 1 | -0.00391941 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00387569 |
| DENND5A | DENN/MADD domain containing 5A | -0.0038688 |
| PRKCSH | protein kinase C substrate 80K-H | -0.00385792 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00384756 |
| F5 | coagulation factor V (proaccelerin, labile factor) | -0.00384685 |
| CD34 | CD34 molecule | -0.00384047 |
| NPTN | neuroplastin | -0.00383184 |
| SCPEP1 | serine carboxypeptidase 1 | -0.00382625 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00380499 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | -0.00379088 |
| MAP7 | microtubule-associated protein 7 | -0.00376421 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.00376257 |
| CD300A | CD300a molecule | -0.00375491 |
| PDZD2 | PDZ domain containing 2 | -0.00375347 |
| NRCAM | neuronal cell adhesion molecule | -0.00374669 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.0037466 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 | -0.00374495 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00374429 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | -0.00374422 |
| CAMP | cathelicidin antimicrobial peptide | -0.00370158 |
| CSAD | cysteine sulfinic acid decarboxylase | -0.00369806 |
| ACOT9 | acyl-CoA thioesterase 9 | -0.00369765 |
| PITX3 | paired-like homeodomain 3 | -0.00369378 |
| C1ORF115 | chromosome 1 open reading frame 115 | -0.00368656 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00368338 |
| S100A9 | S100 calcium binding protein A9 | -0.00367677 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | -0.00367313 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.00364018 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.00363289 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.00363207 |
| LONP2 | lon peptidase 2, peroxisomal | -0.00362708 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.00362651 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.00362548 |
| CPE | carboxypeptidase E | -0.0036172 |
| ABLIM1 | actin binding LIM protein 1 | -0.00360229 |
| PPL | periplakin | -0.00358837 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00358648 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00358425 |
| SDC2 | syndecan 2 | -0.00358368 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.00357666 |
| TWIST1 | twist family bHLH transcription factor 1 | -0.00352878 |
| DCN | decorin | -0.00351088 |
| PFKP | phosphofructokinase, platelet | -0.00350457 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.00350303 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00348785 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.00345227 |
| EGFR | epidermal growth factor receptor | -0.00343945 |
| PCNA | proliferating cell nuclear antigen | -0.0034366 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0034343 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00342933 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.00342212 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 | -0.0034219 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.00340976 |
| FDX1 | ferredoxin 1 | -0.00340356 |
| EHBP1 | EH domain binding protein 1 | -0.00339527 |
| ANGPT1 | angiopoietin 1 | -0.00339311 |
| FABP7 | fatty acid binding protein 7, brain | -0.00338733 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | -0.00338056 |
| CDK19 | cyclin-dependent kinase 19 | -0.0033777 |
| MINK1 | misshapen-like kinase 1 | -0.00336647 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00336621 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00336232 |
| EDNRA | endothelin receptor type A | -0.00335616 |
| MYO1F | myosin IF | -0.00334817 |
| INSM1 | insulinoma-associated 1 | -0.00334153 |
| PTN | pleiotrophin | -0.00334043 |
| CHKA | choline kinase alpha | -0.0033294 |
| PTCH1 | patched 1 | -0.00332763 |
| SUSD6 | sushi domain containing 6 | -0.00332441 |
| COL6A3 | collagen, type VI, alpha 3 | -0.00332182 |
| MYO5C | myosin VC | -0.00331759 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00331609 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00331461 |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) | -0.00331232 |
| OLFML2A | olfactomedin-like 2A | -0.00331104 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00330355 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00330203 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00330171 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.00329875 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.00329759 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | -0.00329309 |
| TLK2 | tousled-like kinase 2 | -0.00327797 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00326949 |
| S100A7 | S100 calcium binding protein A7 | -0.00326822 |
| ASPH | aspartate beta-hydroxylase | -0.00325559 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00324672 |
| SHOX2 | short stature homeobox 2 | -0.00324535 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | -0.0032396 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00323571 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00322825 |
| ELAPOR1 | endosome-lysosome associated apoptosis and autophagy regulator 1 | -0.003228 |
| CHGB | chromogranin B | -0.00322644 |
| SNX5 | sorting nexin 5 | -0.00322311 |
| PNMA1 | paraneoplastic Ma antigen 1 | -0.00321157 |
| FGB | fibrinogen beta chain | -0.00319621 |
| AK4 | adenylate kinase 4 | -0.00319604 |
| SSX1 | synovial sarcoma, X breakpoint 1 | -0.00319423 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 | -0.00319345 |
| GPX3 | glutathione peroxidase 3 | -0.00318749 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00318569 |
| VLDLR | very low density lipoprotein receptor | -0.00318341 |
| NAA40 | N(alpha)-acetyltransferase 40, NatD catalytic subunit | -0.00318314 |
| FBLN5 | fibulin 5 | -0.00317996 |
| MATN2 | matrilin 2 | -0.00317908 |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase | -0.00316935 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00316201 |
| ANXA6 | annexin A6 | -0.00315352 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.00315185 |
| ARCN1 | archain 1 | -0.0031507 |
| SCG5 | secretogranin V | -0.00314348 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00314325 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta | -0.00313613 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.00313141 |
| PCBP2 | poly(rC) binding protein 2 | -0.00312213 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | -0.00312046 |
| ENO1 | enolase 1, (alpha) | -0.00311553 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.00311073 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.00309775 |
| KLF2 | Kruppel-like factor 2 | -0.00309025 |
| GSDMB | gasdermin B | -0.00308865 |
| TRRAP | transformation/transcription domain-associated protein | -0.00308821 |
| OPHN1 | oligophrenin 1 | -0.00308805 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.00307921 |
