HIVEP2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description human immunodeficiency virus type I enhancer binding protein 2|This gene encodes a member of a family of closely related, large, zinc finger-containing transcription factors. The encoded protein regulates transcription by binding to regulatory regions of various cellular and viral genes that maybe involved in growth, development and metastasis. The protein contains the ZAS domain comprised of two widely separated regions of zinc finger motifs, a stretch of highly acidic amino acids and a serine/threonine-rich sequence. [provided by RefSeq, Nov 2012] (NCBI Entrez Gene Database, 3097)
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Genes

289 genes differentially expressed following the HIVEP2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 3.39481
C11ORF96 chromosome 11 open reading frame 96 3.39481
ANKRD61 ankyrin repeat domain 61 3.39481
ACE2 angiotensin I converting enzyme 2 3.39481
TMEM45B transmembrane protein 45B 3.39481
TPSG1 tryptase gamma 1 3.39481
CCR3 chemokine (C-C motif) receptor 3 3.39481
PROX2 prospero homeobox 2 3.39481
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 3.39481
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 3.39481
AMBP alpha-1-microglobulin/bikunin precursor 3.39481
HBZ hemoglobin, zeta 3.39481
CBX4 chromobox homolog 4 3.39481
CTRC chymotrypsin C (caldecrin) 3.39481
TMEM270 transmembrane protein 270 3.39481
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 3.39481
WDR64 WD repeat domain 64 3.39481
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 3.33027
BSND barttin CLCNK-type chloride channel accessory beta subunit 3.33027
TDRD6 tudor domain containing 6 3.33027
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 3.33027
OR52A5 olfactory receptor, family 52, subfamily A, member 5 3.33027
SPINK6 serine peptidase inhibitor, Kazal type 6 3.33027
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 3.33027
GLUD2 glutamate dehydrogenase 2 3.33027
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 3.33027
TEX13B testis expressed 13B 3.33027
FOXI1 forkhead box I1 3.33027
SH2D6 SH2 domain containing 6 3.33027
CEP295NL CEP295 N-terminal like 3.33027
ARSF arylsulfatase F 3.33027
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 3.33027
PMCH pro-melanin-concentrating hormone 3.33027
EPHB3 EPH receptor B3 3.33027
TDO2 tryptophan 2,3-dioxygenase 3.33027
MYL4 myosin, light chain 4, alkali; atrial, embryonic 3.33027
PRDM12 PR domain containing 12 3.33027
OC90 otoconin 90 3.33027
FABP12 fatty acid binding protein 12 3.33027
CRH corticotropin releasing hormone 3.33027
RGPD4 RANBP2-like and GRIP domain containing 4 3.33027
TMEM217 transmembrane protein 217 3.33027
MS4A15 membrane-spanning 4-domains, subfamily A, member 15 3.33027
NOTUM notum pectinacetylesterase homolog (Drosophila) 3.33027
SFTPC surfactant protein C 3.33027
RFPL2 ret finger protein-like 2 3.33027
TRIM77 tripartite motif containing 77 3.33027
FGF9 fibroblast growth factor 9 3.33027
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 3.33027
SMLR1 small leucine-rich protein 1 3.33027
C16ORF90 chromosome 16 open reading frame 90 3.33027
RD3 retinal degeneration 3 3.33027
PNLIPRP3 pancreatic lipase-related protein 3 3.33027
YIPF7 Yip1 domain family, member 7 3.33027
H2BC1 H2B clustered histone 1 3.33027
TCIM transcriptional and immune response regulator 3.33027
CLXN calaxin 3.33027
TERB1 telomere repeat binding bouquet formation protein 1 3.33027
H2BW1 H2B.W histone 1 3.33027
CFAP276 cilia and flagella associated protein 276 3.33027
GLYATL1B glycine-N-acyltransferase like 1B 3.33027
SPAAR small regulatory polypeptide of amino acid response 3.33027
FAM240A family with sequence similarity 240 member A 3.33027
GOLGA8R golgin A8 family, member R 3.33027
CCDC190 coiled-coil domain containing 190 3.33027
RDH8 retinol dehydrogenase 8 (all-trans) 3.33027
ZNF492 zinc finger protein 492 3.33027
CD300E CD300e molecule 3.33027
ATP13A5 ATPase type 13A5 3.33027
CLDN9 claudin 9 3.33027
ITK IL2-inducible T-cell kinase 3.33027
ERVFRD-1 endogenous retrovirus group FRD, member 1 3.33027
CD79A CD79a molecule, immunoglobulin-associated alpha 3.33027
IL5 interleukin 5 3.33027
GJD4 gap junction protein, delta 4, 40.1kDa 3.33027
LRRC70 leucine rich repeat containing 70 3.33027
RNF183 ring finger protein 183 3.33027
DYNLRB2 dynein, light chain, roadblock-type 2 3.33027
OR52E4 olfactory receptor, family 52, subfamily E, member 4 3.33027
DOK7 docking protein 7 3.33027
LOC122394732 uncharacterized LOC122394732 3.33027
GAS2L2 growth arrest-specific 2 like 2 3.33027
SH2D4B SH2 domain containing 4B 3.33027
PKDREJ polycystin (PKD) family receptor for egg jelly 3.33027
TRADD TNFRSF1A-associated via death domain 3.33027
DUOX2 dual oxidase 2 3.33027
SYNE3 spectrin repeat containing, nuclear envelope family member 3 3.33027
LCT lactase 3.33027
OR56A4 olfactory receptor, family 56, subfamily A, member 4 3.33027
SMIM23 small integral membrane protein 23 3.33027
APOF apolipoprotein F 3.33027
OR3A1 olfactory receptor, family 3, subfamily A, member 1 3.33027
ELANE elastase, neutrophil expressed 3.33027
TBC1D28 TBC1 domain family, member 28 3.33027
RGR retinal G protein coupled receptor 3.33027
TECRL trans-2,3-enoyl-CoA reductase-like 3.33027
POU3F3 POU class 3 homeobox 3 3.33027
APOC2 apolipoprotein C-II 3.33027
IRGM immunity-related GTPase family, M 3.33027
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 3.33027
GSC2 goosecoid homeobox 2 3.33027
CSF1R colony stimulating factor 1 receptor 3.33027
PSG8 pregnancy specific beta-1-glycoprotein 8 3.33027
LHX9 LIM homeobox 9 3.33027
CTSS cathepsin S 3.33027
NT5C1B 5'-nucleotidase, cytosolic IB 3.33027
SI sucrase-isomaltase (alpha-glucosidase) 3.33027
PRR35 proline rich 35 3.33027
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 3.33027
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 3.33027
PROK1 prokineticin 1 3.33027
TRIML1 tripartite motif family-like 1 3.33027
BCO1 beta-carotene oxygenase 1 3.33027
ODF4 outer dense fiber of sperm tails 4 3.33027
DCAF8L2 DDB1 and CUL4 associated factor 8-like 2 3.33027
CLCA1 chloride channel accessory 1 3.33027
AOC1 amine oxidase, copper containing 1 3.33027
STOML3 stomatin (EPB72)-like 3 3.33027
OR14A16 olfactory receptor, family 14, subfamily A, member 16 3.33027
CD80 CD80 molecule 3.33027
SSX1 synovial sarcoma, X breakpoint 1 3.33027
PRSS33 protease, serine, 33 3.33027
ZPLD1 zona pellucida-like domain containing 1 3.33027
TGM4 transglutaminase 4 3.33027
ADRA1B adrenoceptor alpha 1B 3.33027
IFNE interferon, epsilon 3.33027
TSSK1B testis-specific serine kinase 1B 3.33027
HIGD1C HIG1 hypoxia inducible domain family, member 1C 3.33027
SOST sclerostin 3.33027
ADAM20 ADAM metallopeptidase domain 20 3.33027
GH1 growth hormone 1 3.33027
GH2 growth hormone 2 3.33027
POTEF POTE ankyrin domain family, member F 3.33027
GPR78 G protein-coupled receptor 78 3.33027
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like 3.28912
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 3.16433
PSD3 pleckstrin and Sec7 domain containing 3 3.04329
CIB1 calcium and integrin binding 1 (calmyrin) 3.04329
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 3.03186
SHISAL1 shisa like 1 2.91777
FAM107B family with sequence similarity 107, member B 2.85937
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 2.84416
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 2.81374
WRN Werner syndrome, RecQ helicase-like 2.78289
TMEM185A transmembrane protein 185A 2.63637
POFUT3 protein O-fucosyltransferase 3 2.552
SYNPR synaptoporin 2.53707
C9ORF152 chromosome 9 open reading frame 152 2.50999
TMPRSS11D transmembrane protease, serine 11D 2.50999
RHOXF2 Rhox homeobox family, member 2 2.50999
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 2.50999
BAHD1 bromo adjacent homology domain containing 1 2.4936
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 2.4673
HLA-DMA major histocompatibility complex, class II, DM alpha 2.43153
SACK1F scaffolding CK1 anchoring protein F 2.38443
FAM185A family with sequence similarity 185, member A 2.37073
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 2.36969
FOLR1 folate receptor 1 (adult) 2.36969
KLHL31 kelch-like family member 31 2.36969
RNF17 ring finger protein 17 2.36969
KRT222 keratin 222, type II 2.36969
SFXN3 sideroflexin 3 2.36969
PGAM2 phosphoglycerate mutase 2 (muscle) 2.36969
GGACT gamma-glutamylamine cyclotransferase 2.36969
ZGLP1 zinc finger, GATA-like protein 1 2.36969
ACTA1 actin, alpha 1, skeletal muscle 2.36969
MAP7 microtubule-associated protein 7 2.36645
PLPP6 phospholipid phosphatase 6 2.34742
DNAH10 dynein, axonemal, heavy chain 10 2.34029
SLC26A1 solute carrier family 26 (anion exchanger), member 1 2.34029
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2.30686
SPATA22 spermatogenesis associated 22 2.30661
ZNF16 zinc finger protein 16 2.25781
BRD9 bromodomain containing 9 2.23467
LRRC9 leucine rich repeat containing 9 2.22462
GPR107 G protein-coupled receptor 107 2.22145
TBC1D2 TBC1 domain family, member 2 2.22031
WDR37 WD repeat domain 37 2.1821
TFE3 transcription factor binding to IGHM enhancer 3 2.17395
PHF6 PHD finger protein 6 2.17395
POTEI POTE ankyrin domain family, member I 2.17395
MT2A metallothionein 2A 2.14257
KCP kielin/chordin-like protein 2.10259
YLPM1 YLP motif containing 1 2.08584
ZNF713 zinc finger protein 713 2.08584
EIF3A eukaryotic translation initiation factor 3, subunit A 2.08584
ERVMER34-1 endogenous retrovirus group MER34, member 1 2.05467
NMU neuromedin U 2.04332
RNF185 ring finger protein 185 2.01648
HAUS2 HAUS augmin-like complex, subunit 2 2.00994
SIRAL2 SIR2 antiphage like 2 2.00994

decreased expression

Symbol Name Standardized Value
OR52N2 olfactory receptor, family 52, subfamily N, member 2 -3.39481
AURKC aurora kinase C -3.39481
HHAT hedgehog acyltransferase -3.39481
IFI16 interferon, gamma-inducible protein 16 -3.39481
CORIN corin, serine peptidase -3.39481
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled -3.39481
ZBTB42 zinc finger and BTB domain containing 42 -3.39481
ARSI arylsulfatase family, member I -3.39481
BMP2 bone morphogenetic protein 2 -3.39481
COL16A1 collagen, type XVI, alpha 1 -3.39481
TDRD12 tudor domain containing 12 -3.33027
LRRC45 leucine rich repeat containing 45 -3.33027
H4C2 H4 clustered histone 2 -3.33027
ARHGAP36 Rho GTPase activating protein 36 -3.28912
CD164L2 CD164 sialomucin-like 2 -3.28912
PANO1 proapoptotic nucleolar protein 1 -3.28912
SH2D7 SH2 domain containing 7 -3.28912
ARGFX arginine-fifty homeobox -3.28912
AMDHD1 amidohydrolase domain containing 1 -3.28912
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -3.28912
AHSG alpha-2-HS-glycoprotein -3.28912
FAM167A family with sequence similarity 167, member A -3.28912
RP1 retinitis pigmentosa 1 (autosomal dominant) -3.28912
GGN gametogenetin -3.28912
DCST1 DC-STAMP domain containing 1 -3.28912
TMEM215 transmembrane protein 215 -3.28912
FNDC1 fibronectin type III domain containing 1 -3.28912
FPR3 formyl peptide receptor 3 -3.28912
GPR146 G protein-coupled receptor 146 -3.28912
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1 -3.28912
PCDH12 protocadherin 12 -3.28912
BAIAP2L2 BAI1-associated protein 2-like 2 -3.28912
H3C13 H3 clustered histone 13 -3.28912
ADAM7 ADAM metallopeptidase domain 7 -3.28912
NPFF neuropeptide FF-amide peptide precursor -3.28912
LECT2 leukocyte cell-derived chemotaxin 2 -3.28912
RTBDN retbindin -3.28912
TTC36 tetratricopeptide repeat domain 36 -3.28912
CHRD chordin -3.28912
PRRT4 proline-rich transmembrane protein 4 -3.28912
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6 -3.24523
TCEAL9 transcription elongation factor A like 9 -3.20126
ZNF32 zinc finger protein 32 -3.15068
RGS5 regulator of G-protein signaling 5 -2.98767
LARGE2 LARGE xylosyl- and glucuronyltransferase 2 -2.9538
CERS5 ceramide synthase 5 -2.88262
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 -2.83307
C10ORF95 chromosome 10 open reading frame 95 -2.79448
SRSF3 serine/arginine-rich splicing factor 3 -2.76092
LRP2 low density lipoprotein receptor-related protein 2 -2.61149
ARMCX1 armadillo repeat containing, X-linked 1 -2.59738
SLC35G1 solute carrier family 35, member G1 -2.57559
NRARP NOTCH-regulated ankyrin repeat protein -2.57559
GARIN1B golgi associated RAB2 interactor 1B -2.5337
RAD51 RAD51 recombinase -2.50999
RAB39A RAB39A, member RAS oncogene family -2.43578
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.43153
GTF2B general transcription factor IIB -2.39167
ZNF860 zinc finger protein 860 -2.38443
MIXL1 Mix paired-like homeobox -2.34742
POGLUT3 protein O-glucosyltransferase 3 -2.34029
PRKD2 protein kinase D2 -2.32857
PTPN21 protein tyrosine phosphatase, non-receptor type 21 -2.29669
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -2.28382
PHKA2 phosphorylase kinase, alpha 2 (liver) -2.28364
FAM156A family with sequence similarity 156, member A -2.28324
SYNGAP1 synaptic Ras GTPase activating protein 1 -2.28324
SYT12 synaptotagmin XII -2.2779
NTMT2 N-terminal Xaa-Pro-Lys N-methyltransferase 2 -2.25862
C4ORF50 chromosome 4 open reading frame 50 -2.23467
TMEM190 transmembrane protein 190 -2.23467
MID2 midline 2 -2.23467
OR2AG2 olfactory receptor, family 2, subfamily AG, member 2 -2.23467
MYCT1 myc target 1 -2.20903
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 -2.20903
ADH6 alcohol dehydrogenase 6 (class V) -2.20903
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase -2.19728
FAM110D family with sequence similarity 110, member D -2.19253
CRYBA4 crystallin, beta A4 -2.17395
LYSET lysosomal enzyme trafficking factor -2.17395
APH1B APH1B gamma secretase subunit -2.17395
CD200R1L CD200 receptor 1-like -2.17395
VILL villin-like -2.17395
NR1I2 nuclear receptor subfamily 1, group I, member 2 -2.17395
SYTL5 synaptotagmin-like 5 -2.17395
KLRB1 killer cell lectin-like receptor subfamily B, member 1 -2.17395
GPA33 glycoprotein A33 (transmembrane) -2.1388
NR3C2 nuclear receptor subfamily 3, group C, member 2 -2.116
CALB1 calbindin 1, 28kDa -2.11083
SPRYD4 SPRY domain containing 4 -2.10268
CLYBL citrate lyase beta like -2.08986
RARB retinoic acid receptor, beta -2.08584
MACIR macrophage immunometabolism regulator -2.07469
PPP5C protein phosphatase 5, catalytic subunit -2.07469
CHD9NB CHD9 neighbor -2.07469
EARS2 glutamyl-tRNA synthetase 2, mitochondrial -2.06024
KCNK6 potassium channel, two pore domain subfamily K, member 6 -2.05125
TARDBP TAR DNA binding protein -2.00994