HLA-A Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description major histocompatibility complex, class I, A|HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3105)
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Genes

368 genes differentially expressed following the HLA-A gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
NKPD1 NTPase, KAP family P-loop domain containing 1 4.26573
TAS1R1 taste receptor, type 1, member 1 4.26573
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B 4.26573
BDKRB2 bradykinin receptor B2 4.26573
KLK5 kallikrein-related peptidase 5 4.26573
SFRP5 secreted frizzled-related protein 5 4.26573
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 4.26573
LCNL1 lipocalin-like 1 4.26573
BTN1A1 butyrophilin, subfamily 1, member A1 4.26573
MLANA melan-A 4.26573
CSAG3 CSAG family, member 3 4.26573
CD38 CD38 molecule 4.26573
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 4.26573
KLHL1 kelch-like family member 1 4.26573
KIF19 kinesin family member 19 4.26573
UTS2 urotensin 2 4.26573
BRDT bromodomain, testis-specific 4.26573
FNDC1 fibronectin type III domain containing 1 4.26573
RAG2 recombination activating gene 2 4.26573
CIMIP4 ciliary microtubule inner protein 4 4.26573
TAS2R5 taste receptor, type 2, member 5 4.26573
MS4A15 membrane-spanning 4-domains, subfamily A, member 15 4.26573
PTGER3 prostaglandin E receptor 3 (subtype EP3) 4.26573
CNTFR ciliary neurotrophic factor receptor 4.26573
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10 4.26573
TGFB3 transforming growth factor, beta 3 4.26573
RIPPLY2 ripply transcriptional repressor 2 4.26573
BSND barttin CLCNK-type chloride channel accessory beta subunit 4.22705
LRRD1 leucine-rich repeats and death domain containing 1 4.22705
FPR2 formyl peptide receptor 2 4.22705
PLIN1 perilipin 1 4.22705
SYCP2 synaptonemal complex protein 2 4.22705
OR11H4 olfactory receptor, family 11, subfamily H, member 4 4.22705
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 4.22705
CD1C CD1c molecule 4.22705
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7 4.22705
NRN1 neuritin 1 4.22705
LAPTM5 lysosomal protein transmembrane 5 4.22705
SRL sarcalumenin 4.22705
GPR75 G protein-coupled receptor 75 4.22705
FGD2 FYVE, RhoGEF and PH domain containing 2 4.22705
TRIM17 tripartite motif containing 17 4.22705
SIRPB1 signal-regulatory protein beta 1 4.22705
RSPO1 R-spondin 1 4.22705
ASPA aspartoacylase 4.22705
ADAD2 adenosine deaminase domain containing 2 4.22705
FHL5 four and a half LIM domains 5 4.22705
ENTHD1 ENTH domain containing 1 4.22705
OTUD6A OTU deubiquitinase 6A 4.22705
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 4.22705
TNS4 tensin 4 4.22705
MEIKIN meiotic kinetochore factor 4.22705
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2 4.22705
TUBB8 tubulin, beta 8 class VIII 4.22705
ASB12 ankyrin repeat and SOCS box containing 12 4.22705
PCDHB8 protocadherin beta 8 4.22705
HES7 hes family bHLH transcription factor 7 4.22705
NOD2 nucleotide-binding oligomerization domain containing 2 4.22705
ARSI arylsulfatase family, member I 4.22705
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 4.22705
FOXR1 forkhead box R1 4.22705
PLCH2 phospholipase C, eta 2 4.22705
DMRTC1B DMRT-like family C1B 4.22705
ASB17 ankyrin repeat and SOCS box containing 17 4.22705
ANKK1 ankyrin repeat and kinase domain containing 1 4.22705
COXFA4L3 cytochrome c oxidase associated subunit FA4L3 4.22705
ERVW-1 endogenous retrovirus group W, member 1 4.22705
ALDOB aldolase B, fructose-bisphosphate 4.22705
BEND2 BEN domain containing 2 4.22705
ACER1 alkaline ceramidase 1 4.22705
ELOVL3 ELOVL fatty acid elongase 3 4.22705
WDR64 WD repeat domain 64 4.22705
TSPAN1 tetraspanin 1 4.22705
SPATA22 spermatogenesis associated 22 4.22705
CFC1 cripto, FRL-1, cryptic family 1 4.22705
GATA5 GATA binding protein 5 4.22705
DERPC DERPC proline and glycine rich nuclear protein 4.22705
CCN5 cellular communication network factor 5 4.22705
EXOC1L exocyst complex component 1 like 4.22705
FAM240A family with sequence similarity 240 member A 4.22705
WASL-DT WASL divergent transcript 4.22705
SMIM45 small integral membrane protein 45 4.22705
C20ORF204 chromosome 20 open reading frame 204 4.22705
H3-7 H3.7 histone (putative) 4.22705
CFAP299 cilia and flagella associated protein 299 4.22705
TERB2 telomere repeat binding bouquet formation protein 2 4.22705
CLXN calaxin 4.22705
CCDC198 coiled-coil domain containing 198 4.22705
LTF lactotransferrin 4.22705
LTA lymphotoxin alpha 4.22705
DSG1 desmoglein 1 4.22705
FAM43B family with sequence similarity 43, member B 4.22705
CRLF2 cytokine receptor-like factor 2 4.22705
C4ORF17 chromosome 4 open reading frame 17 4.22705
DMP1 dentin matrix acidic phosphoprotein 1 4.22705
NKX2-5 NK2 homeobox 5 4.22705
CAPN14 calpain 14 4.22705
RAB44 RAB44, member RAS oncogene family 4.22705
IL12RB1 interleukin 12 receptor, beta 1 4.22705
ATP13A5 ATPase type 13A5 4.22705
THPO thrombopoietin 4.22705
C3ORF80 chromosome 3 open reading frame 80 4.22705
PCDHGC5 protocadherin gamma subfamily C, 5 4.22705
FGFBP1 fibroblast growth factor binding protein 1 4.22705
STARD6 StAR-related lipid transfer (START) domain containing 6 4.22705
ARHGAP15 Rho GTPase activating protein 15 4.22705
CDSN corneodesmosin 4.22705
ARMS2 age-related maculopathy susceptibility 2 4.22705
PIWIL3 piwi-like RNA-mediated gene silencing 3 4.22705
NPIPB9 nuclear pore complex interacting protein family, member B9 4.22705
ANXA13 annexin A13 4.22705
LOC124901872 uncharacterized LOC124901872 4.22705
PVRIG poliovirus receptor related immunoglobulin domain containing 4.22705
BMP3 bone morphogenetic protein 3 4.22705
POPDC2 popeye domain containing 2 4.22705
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 4.22705
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 4.22705
NUTM2F NUT family member 2F 4.22705
CARD6 caspase recruitment domain family, member 6 4.22705
TBC1D26 TBC1 domain family, member 26 4.22705
FZD1 frizzled class receptor 1 4.22705
PGR progesterone receptor 4.22705
GPR61 G protein-coupled receptor 61 4.22705
GLOD5 glyoxalase domain containing 5 4.22705
CD27 CD27 molecule 4.22705
IL37 interleukin 37 4.22705
TRAF3IP3 TRAF3 interacting protein 3 4.22705
PPP1R3G protein phosphatase 1, regulatory subunit 3G 4.22705
SH2D1B SH2 domain containing 1B 4.22705
OR10G3 olfactory receptor, family 10, subfamily G, member 3 4.22705
ADRA1B adrenoceptor alpha 1B 4.22705
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 4.22705
ARGFX arginine-fifty homeobox 4.22705
PRSS57 protease, serine, 57 4.22705
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 4.22705
OR3A3 olfactory receptor, family 3, subfamily A, member 3 4.22705
ARR3 arrestin 3, retinal (X-arrestin) 4.22705
NCR3 natural cytotoxicity triggering receptor 3 4.22705
KISS1 KiSS-1 metastasis-suppressor 4.22705
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 4.22705
SMR3B submaxillary gland androgen regulated protein 3B 4.22705
IL1B interleukin 1, beta 4.22705
COX7B2 cytochrome c oxidase subunit VIIb2 4.22705
MUC16 mucin 16, cell surface associated 4.22705
TG thyroglobulin 4.22705
OR56A3 olfactory receptor, family 56, subfamily A, member 3 4.22705
TBPL2 TATA box binding protein like 2 4.22705
OTOP2 otopetrin 2 4.22705
STAB1 stabilin 1 4.22705
C22ORF15 chromosome 22 open reading frame 15 4.22705
KRT3 keratin 3, type II 4.22705
SPZ1 spermatogenic leucine zipper 1 4.22705
GFI1B growth factor independent 1B transcription repressor 4.22705
DMRT1 doublesex and mab-3 related transcription factor 1 4.22705
BCO1 beta-carotene oxygenase 1 4.22705
GSC2 goosecoid homeobox 2 4.22705
OR5A2 olfactory receptor, family 5, subfamily A, member 2 4.22705
EBI3 Epstein-Barr virus induced 3 4.22705
C2ORF78 chromosome 2 open reading frame 78 4.22705
EMCN endomucin 4.22705
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 4.22705
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 4.22705
ATAD3C ATPase family, AAA domain containing 3C 4.22705
BOLA2 bolA family member 2 4.22705
EVPL envoplakin 4.22705
SFTA2 surfactant associated 2 4.22705
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6 4.22705
PRR22 proline rich 22 4.22705
EOMES eomesodermin 4.22705
ACADL acyl-CoA dehydrogenase, long chain 4.22705
NEUROD4 neuronal differentiation 4 4.22705
IRX3 iroquois homeobox 3 4.22705
CSF1R colony stimulating factor 1 receptor 4.22705
TRIM29 tripartite motif containing 29 4.22705
AMPD1 adenosine monophosphate deaminase 1 4.22705
CD34 CD34 molecule 4.22705
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 4.22705
TM4SF19 transmembrane 4 L six family member 19 4.22705
CD3E CD3e molecule, epsilon (CD3-TCR complex) 4.22705
SPHK1 sphingosine kinase 1 4.22705
LPIN3 lipin 3 4.14622
KLHDC1 kelch domain containing 1 4.14622
ADORA2B adenosine A2b receptor 4.05365
PMP22 peripheral myelin protein 22 3.41778
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 3.37059
MSH3 mutS homolog 3 3.37059
SPHK2 sphingosine kinase 2 3.14092
PLXNA4 plexin A4 3.12092
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 3.06824
ADGRG3 adhesion G protein-coupled receptor G3 3.06824
SETD3 SET domain containing 3 3.06824
RASL11A RAS-like, family 11, member A 3.06824
CFAP141 cilia and flagella associated protein 141 3.06824
MUC6 mucin 6, oligomeric mucus/gel-forming 3.06824
ADTRP androgen-dependent TFPI-regulating protein 3.06824
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 2.98823
FAM181B family with sequence similarity 181, member B 2.94948
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 2.91073
GLB1L2 galactosidase, beta 1-like 2 2.91073
SCN5A sodium channel, voltage gated, type V alpha subunit 2.88806
GPR3 G protein-coupled receptor 3 2.87922
RABGGTB Rab geranylgeranyltransferase, beta subunit 2.83358
ZNF331 zinc finger protein 331 2.71054
SNED1 sushi, nidogen and EGF-like domains 1 2.70105
IFTAP intraflagellar transport associated protein 2.66332
ARHGAP5 Rho GTPase activating protein 5 2.63419
ZNF185 zinc finger protein 185 (LIM domain) 2.61516
TINAGL1 tubulointerstitial nephritis antigen-like 1 2.59889
SHISAL2B shisa like 2B 2.59116
GEN1 GEN1 Holliday junction 5' flap endonuclease 2.58361
C14ORF39 chromosome 14 open reading frame 39 2.54741
PDE12 phosphodiesterase 12 2.54529
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 2.54096
DTX3L deltex 3 like, E3 ubiquitin ligase 2.54096
AXL AXL receptor tyrosine kinase 2.49737
TSPAN7 tetraspanin 7 2.4859
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit 2.48135
TTI2 TELO2 interacting protein 2 2.44447
ADGRB2 adhesion G protein-coupled receptor B2 2.43504
PPL periplakin 2.42497
UNKL unkempt family zinc finger-like 2.40357
TOMM70 translocase of outer mitochondrial membrane 70 2.39906
GJB5 gap junction protein, beta 5, 31.1kDa 2.39625
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 2.38805
ZFP62 ZFP62 zinc finger protein 2.36773
F2 coagulation factor II (thrombin) 2.36144
SCRT2 scratch family zinc finger 2 2.36144
LTBP2 latent transforming growth factor beta binding protein 2 2.35749
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 2.35749
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 2.32857
TMEM31 transmembrane protein 31 2.31181
KLRF1 killer cell lectin-like receptor subfamily F, member 1 2.30705
LRP1 low density lipoprotein receptor-related protein 1 2.28327
COA3 cytochrome c oxidase assembly factor 3 2.24631
MYSM1 Myb-like, SWIRM and MPN domains 1 2.20789
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.20789
ZFYVE27 zinc finger, FYVE domain containing 27 2.13858
TMEM50A transmembrane protein 50A 2.12553
TPRA1 transmembrane protein, adipocyte asscociated 1 2.10514
PCNX2 pecanex 2 2.10108
ASB7 ankyrin repeat and SOCS box containing 7 2.10108
CDCA5 cell division cycle associated 5 2.09792
SAE1 SUMO1 activating enzyme subunit 1 2.09664
TGOLN2 trans-golgi network protein 2 2.08944
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 2.07844
FAM20B family with sequence similarity 20, member B 2.0659
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 2.0659
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 2.05113
WDR1 WD repeat domain 1 2.03301
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 2.02992
ERN2 endoplasmic reticulum to nucleus signaling 2 2.02992
C12ORF43 chromosome 12 open reading frame 43 2.02885
CTR9 CTR9, Paf1/RNA polymerase II complex component 2.02752
PMF1 polyamine-modulated factor 1 2.02406
HDAC5 histone deacetylase 5 2.01297
CALN1 calneuron 1 2.00798
CD72 CD72 molecule 2.00798

decreased expression

Symbol Name Standardized Value
BAIAP3 BAI1-associated protein 3 -4.26573
DKK2 dickkopf WNT signaling pathway inhibitor 2 -4.26573
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) -4.26573
CCNP cyclin P -4.26573
TICAM1 toll-like receptor adaptor molecule 1 -4.22705
GOLGA6L4 golgin A6 family-like 4 -4.22705
ZIC4 Zic family member 4 -4.22705
SLC67A1 solute carrier family 67 member 1 -4.22705
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -4.22705
MPZL2 myelin protein zero-like 2 -4.22705
DISP2 dispatched homolog 2 (Drosophila) -4.22705
IRF8 interferon regulatory factor 8 -4.22705
KCTD4 potassium channel tetramerization domain containing 4 -4.22705
PNMA6A paraneoplastic Ma antigen family member 6A -4.22705
PRSS21 protease, serine, 21 (testisin) -4.22705
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 -4.22705
HRH4 histamine receptor H4 -4.22705
HES4 hes family bHLH transcription factor 4 -4.22705
RASA4B RAS p21 protein activator 4B -4.22705
MRPL53 mitochondrial ribosomal protein L53 -4.22705
GAGE10 G antigen 10 -4.22705
TEX46 testis expressed 46 -4.22705
CFAP157 cilia and flagella associated protein 157 -4.22705
PDF peptide deformylase (mitochondrial) -4.22705
PTH2 parathyroid hormone 2 -4.22705
CRHR1 corticotropin releasing hormone receptor 1 -4.22705
GC group-specific component (vitamin D binding protein) -4.22705
WFDC8 WAP four-disulfide core domain 8 -4.22705
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal -4.22705
DUSP13B dual specificity phosphatase 13B -4.22705
CFAP90 cilia and flagella associated protein 90 -4.22705
BCAN brevican -4.16341
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 -4.16341
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -3.89572
ECRG4 ECRG4 augurin precursor -3.31151
RAD17 RAD17 homolog (S. pombe) -3.2974
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -3.18728
POLN polymerase (DNA directed) nu -3.14457
FAM110D family with sequence similarity 110, member D -3.12092
TRIM68 tripartite motif containing 68 -3.12092
ARID5A AT rich interactive domain 5A (MRF1-like) -3.06824
ZNF407 zinc finger protein 407 -3.05169
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -2.93701
EHD3 EH-domain containing 3 -2.92108
TMEM200C transmembrane protein 200C -2.91145
PCDHA5 protocadherin alpha 5 -2.91073
FABP6 fatty acid binding protein 6, ileal -2.88368
ZNF765 zinc finger protein 765 -2.78021
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.7373
TMOD2 tropomodulin 2 (neuronal) -2.70105
EIF1AX eukaryotic translation initiation factor 1A, X-linked -2.68579
ZSCAN23 zinc finger and SCAN domain containing 23 -2.64484
ZNF639 zinc finger protein 639 -2.64484
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K -2.63579
IL17RC interleukin 17 receptor C -2.63343
CHP1 calcineurin-like EF-hand protein 1 -2.5694
NICOL1 NELL2 interacting cell ontogeny regulator 1 -2.56713
NXPH2 neurexophilin 2 -2.54458
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor -2.5441
THBS1 thrombospondin 1 -2.51836
SIK2 salt-inducible kinase 2 -2.49737
AARS1 alanyl-tRNA synthetase 1 -2.49696
BICDL2 BICD family like cargo adaptor 2 -2.49424
ARL2 ADP-ribosylation factor-like 2 -2.47367
CREB3L2 cAMP responsive element binding protein 3-like 2 -2.47354
SPOUT1 SPOUT domain containing methyltransferase 1 -2.46477
LIME1 Lck interacting transmembrane adaptor 1 -2.44447
ZNF446 zinc finger protein 446 -2.44447
NR1D1 nuclear receptor subfamily 1, group D, member 1 -2.42497
FOSL2 FOS-like antigen 2 -2.42497
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 -2.42497
GRPR gastrin-releasing peptide receptor -2.42497
RCN2 reticulocalbin 2, EF-hand calcium binding domain -2.41427
TGDS TDP-glucose 4,6-dehydratase -2.41427
STXBP4 syntaxin binding protein 4 -2.35009
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 -2.33208
TMEM258 transmembrane protein 258 -2.30705
C1QTNF7 C1q and tumor necrosis factor related protein 7 -2.2979
FBXO4 F-box protein 4 -2.29554
GPM6A glycoprotein M6A -2.29241
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) -2.28828
MYO7A myosin VIIA -2.28828
CCK cholecystokinin -2.28828
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -2.26846
DPF3 D4, zinc and double PHD fingers, family 3 -2.26846
ETFB electron-transfer-flavoprotein, beta polypeptide -2.22611
GRIK5 glutamate receptor, ionotropic, kainate 5 -2.21923
POT1 protection of telomeres 1 -2.21923
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 -2.21472
PALLD palladin, cytoskeletal associated protein -2.20924
APCDD1L adenomatosis polyposis coli down-regulated 1-like -2.20304
NENF neudesin neurotrophic factor -2.19536
CELF4 CUGBP, Elav-like family member 4 -2.17724
HLA-A major histocompatibility complex, class I, A -2.15827
RBBP7 retinoblastoma binding protein 7 -2.13767
ZFPL1 zinc finger protein-like 1 -2.13146
ARFGEF3 ARFGEF family member 3 -2.13146
FAM3C family with sequence similarity 3, member C -2.1291
USP31 ubiquitin specific peptidase 31 -2.11942
PTPRE protein tyrosine phosphatase, receptor type, E -2.11874
DENND2C DENN/MADD domain containing 2C -2.10108
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 -2.09204
PFAS phosphoribosylformylglycinamidine synthase -2.08215
SDF2L1 stromal cell-derived factor 2-like 1 -2.07964
MLYCD malonyl-CoA decarboxylase -2.0666
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI -2.0649
POLR2M polymerase (RNA) II (DNA directed) polypeptide M -2.05553
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 -2.05021
KARS1 lysyl-tRNA synthetase 1 -2.05021
UQCRHL ubiquinol-cytochrome c reductase hinge protein-like -2.04637
FANCG Fanconi anemia, complementation group G -2.03542