| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | major histocompatibility complex, class I, A|HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3105) |
| External Link | https://ncbi.nlm.nih.gov/gene/3105 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the HLA-A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0165545 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.0122952 |
| RAI14 | retinoic acid induced 14 | 0.0114224 |
| KLHL23 | kelch-like family member 23 | 0.011241 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.0110724 |
| NVL | nuclear VCP-like | 0.00976459 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00964227 |
| GNAS | GNAS complex locus | 0.00911747 |
| CHN2 | chimerin 2 | 0.00907745 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 0.00905899 |
| TBC1D31 | TBC1 domain family, member 31 | 0.00895094 |
| SCG5 | secretogranin V | 0.00870839 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00864769 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00863284 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00856348 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00852431 |
| INSM1 | insulinoma-associated 1 | 0.00843179 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00832357 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00817897 |
| GOLGA8H | golgin A8 family, member H | 0.00815141 |
| TOX3 | TOX high mobility group box family member 3 | 0.0080153 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00800673 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00798065 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0078868 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.00785071 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.0077093 |
| GANAB | glucosidase, alpha; neutral AB | 0.00769209 |
| TPX2 | TPX2, microtubule-associated | 0.00768964 |
| PRAME | preferentially expressed antigen in melanoma | 0.00762112 |
| BCHE | butyrylcholinesterase | 0.00748179 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.00742548 |
| FABP1 | fatty acid binding protein 1, liver | 0.00741427 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00740777 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 0.0073436 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.00731676 |
| PCGF2 | polycomb group ring finger 2 | 0.00721627 |
| ACKR3 | atypical chemokine receptor 3 | 0.0071871 |
| SFTPB | surfactant protein B | 0.00716683 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00713333 |
| USP18 | ubiquitin specific peptidase 18 | 0.00710161 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00706249 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | 0.00704776 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.00700003 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.00699788 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00698302 |
| TUBA1A | tubulin, alpha 1a | 0.00696394 |
| CLGN | calmegin | 0.00695515 |
| NREP | neuronal regeneration related protein | 0.00693571 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | 0.00693213 |
| PER3 | period circadian clock 3 | 0.00693172 |
| PCP4 | Purkinje cell protein 4 | 0.00691702 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00690664 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00685668 |
| CHGB | chromogranin B | 0.00685304 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00684701 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein | 0.00683292 |
| RNF130 | ring finger protein 130 | 0.00681853 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.00678941 |
| EPHB2 | EPH receptor B2 | 0.00677092 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00676659 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00675969 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0067419 |
| CCP110 | centriolar coiled coil protein 110kDa | 0.00672658 |
| NUP85 | nucleoporin 85kDa | 0.00671273 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.00669429 |
| OLFM4 | olfactomedin 4 | 0.00667148 |
| KIF20A | kinesin family member 20A | 0.00665912 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00664297 |
| RAPSN | receptor-associated protein of the synapse | 0.0066157 |
| FABP6 | fatty acid binding protein 6, ileal | 0.00656674 |
| NEFH | neurofilament, heavy polypeptide | 0.00655228 |
| CD320 | CD320 molecule | 0.00647504 |
| HPCAL1 | hippocalcin-like 1 | 0.00647097 |
| NMU | neuromedin U | 0.00645744 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 0.00644007 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00638112 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00637753 |
| COL5A1 | collagen, type V, alpha 1 | 0.00637146 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00635622 |
| HOXB2 | homeobox B2 | 0.00634874 |
| CALML4 | calmodulin-like 4 | 0.00630276 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | 0.00628164 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00628083 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00624385 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.0062336 |
| CDC25B | cell division cycle 25B | 0.00622862 |
| MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | 0.00622818 |
| PCNXL4 | pecanex-like 4 (Drosophila) | 0.00622812 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.00622737 |
| RNF144A | ring finger protein 144A | 0.00622662 |
| MX2 | MX dynamin-like GTPase 2 | 0.00619313 |
| CCNB2 | cyclin B2 | 0.00618873 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | 0.00618077 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00611051 |
| SLC38A10 | solute carrier family 38, member 10 | 0.00610991 |
| KLHDC3 | kelch domain containing 3 | 0.00607507 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00607092 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.00606651 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.00604814 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00604637 |
| REG1A | regenerating islet-derived 1 alpha | 0.00603696 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.0060366 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.00603581 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | 0.00600939 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00594247 |
| STAG2 | stromal antigen 2 | 0.00593859 |
| EHBP1 | EH domain binding protein 1 | 0.00593315 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.00592687 |
| FANCG | Fanconi anemia, complementation group G | 0.00590921 |
| RGS5 | regulator of G-protein signaling 5 | 0.00590533 |
| GGCT | gamma-glutamylcyclotransferase | 0.0058832 |
| WIPF1 | WAS/WASL interacting protein family, member 1 | 0.00587767 |
| PLCB4 | phospholipase C, beta 4 | 0.00585504 |
| PLK1 | polo-like kinase 1 | 0.00585334 |
| HOXB6 | homeobox B6 | 0.00583433 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00583253 |
| HSPA13 | heat shock protein 70kDa family, member 13 | 0.00582908 |
| NPR3 | natriuretic peptide receptor 3 | 0.00582387 |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 | 0.00579448 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.0057898 |
| RTN3 | reticulon 3 | 0.00577586 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0057446 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00573673 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00572869 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00572453 |
| PTK7 | protein tyrosine kinase 7 (inactive) | 0.00572031 |
| CCNA2 | cyclin A2 | 0.00571128 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.00570709 |
| FOXM1 | forkhead box M1 | 0.00570455 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00567583 |
| SOCS3 | suppressor of cytokine signaling 3 | 0.00564936 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00564236 |
| LIMA1 | LIM domain and actin binding 1 | 0.00563857 |
| NEUROD1 | neuronal differentiation 1 | 0.00562658 |
| PCYOX1L | prenylcysteine oxidase 1 like | 0.00560806 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00560728 |
| NTS | neurotensin | 0.00560175 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00559893 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0055984 |
| LDLRAP1 | low density lipoprotein receptor adaptor protein 1 | 0.00559591 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.00559518 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00559178 |
| ERLIN1 | ER lipid raft associated 1 | 0.00558241 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 | 0.00557875 |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 | 0.00557394 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00556697 |
| EXPH5 | exophilin 5 | 0.00556043 |
| DMBT1 | deleted in malignant brain tumors 1 | 0.00555936 |
| CKAP2 | cytoskeleton associated protein 2 | 0.00555009 |
| SPART | spartin | 0.00554812 |
| CDK19 | cyclin-dependent kinase 19 | 0.00554462 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | 0.00551294 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00550746 |
| IFI44L | interferon-induced protein 44-like | 0.00548932 |
| FZD2 | frizzled class receptor 2 | 0.00548824 |
| PAX6 | paired box 6 | 0.00548599 |
| ACTL6A | actin-like 6A | 0.00548524 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.00545801 |
| CDC45 | cell division cycle 45 | 0.00545586 |
| APIP | APAF1 interacting protein | 0.00540445 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00539568 |
| ALDH9A1 | aldehyde dehydrogenase 9 family, member A1 | 0.00535447 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.00534831 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00534244 |
| OLFML2A | olfactomedin-like 2A | 0.00533936 |
| NUDT15 | nudix (nucleoside diphosphate linked moiety X)-type motif 15 | 0.0053388 |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 | 0.00533801 |
| TKTL1 | transketolase-like 1 | 0.00530986 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00530277 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.00530221 |
| TGM2 | transglutaminase 2 | 0.00529954 |
| CD96 | CD96 molecule | 0.00529018 |
| FERMT2 | fermitin family member 2 | 0.00528661 |
| INTS6 | integrator complex subunit 6 | 0.00527865 |
| NCAM1 | neural cell adhesion molecule 1 | 0.00525574 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.00525527 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.00522828 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.00522099 |
| RANBP1 | RAN binding protein 1 | 0.00522005 |
| MYO1D | myosin ID | 0.00520995 |
| TRIP13 | thyroid hormone receptor interactor 13 | 0.00520836 |
| OLFM1 | olfactomedin 1 | 0.0052067 |
| RAB33A | RAB33A, member RAS oncogene family | 0.00520626 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.0052051 |
| GALC | galactosylceramidase | 0.00517651 |
| CALD1 | caldesmon 1 | 0.00516711 |
| CRTC3 | CREB regulated transcription coactivator 3 | 0.00515873 |
| SMAD6 | SMAD family member 6 | 0.00513447 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | 0.00513339 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00513259 |
| COPA | coatomer protein complex, subunit alpha | 0.00513191 |
| ACE2 | angiotensin I converting enzyme 2 | 0.00511899 |
| CNR1 | cannabinoid receptor 1 (brain) | 0.00510564 |
| ATF2 | activating transcription factor 2 | 0.0050572 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.00504742 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00504727 |
| TOR1AIP1 | torsin A interacting protein 1 | 0.00504016 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | 0.00503799 |
| NONO | non-POU domain containing, octamer-binding | 0.00503773 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00503696 |
| NID2 | nidogen 2 (osteonidogen) | 0.00502998 |
| PDHX | pyruvate dehydrogenase complex, component X | 0.00502855 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.00501734 |
| PDE8A | phosphodiesterase 8A | 0.0050157 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.00501496 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | 0.0050131 |
| ABHD17A | abhydrolase domain containing 17A | 0.00500976 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00500442 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.00499712 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | 0.00498426 |
| LARS2 | leucyl-tRNA synthetase 2, mitochondrial | 0.00498076 |
| L1CAM | L1 cell adhesion molecule | 0.00497686 |
| PNPLA6 | patatin-like phospholipase domain containing 6 | 0.00497208 |
| RRBP1 | ribosome binding protein 1 | 0.00496956 |
| CRY1 | cryptochrome circadian clock 1 | 0.00496824 |
| TPH1 | tryptophan hydroxylase 1 | 0.00496802 |
| RNF167 | ring finger protein 167 | 0.00496785 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 0.00496691 |
| POGK | pogo transposable element with KRAB domain | 0.00496475 |
| ADGRA2 | adhesion G protein-coupled receptor A2 | 0.00496061 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0049511 |
| AIF1 | allograft inflammatory factor 1 | 0.00494772 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00494669 |
| WWC3 | WWC family member 3 | 0.00494591 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0049426 |
| PLXNC1 | plexin C1 | 0.00493411 |
| TDP1 | tyrosyl-DNA phosphodiesterase 1 | 0.00491901 |
| PFKL | phosphofructokinase, liver | 0.00490496 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00490463 |
| CHODL | chondrolectin | 0.00490132 |
| ADORA2B | adenosine A2b receptor | 0.00489131 |
| ZMYM3 | zinc finger, MYM-type 3 | 0.00489127 |
| SORD | sorbitol dehydrogenase | 0.00489108 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00488918 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00488906 |
| CDCA4 | cell division cycle associated 4 | 0.00488505 |
| SPAST | spastin | 0.00488187 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00487551 |
| CDCA3 | cell division cycle associated 3 | 0.00487389 |
| TRAF5 | TNF receptor-associated factor 5 | 0.004871 |
| PAPOLG | poly(A) polymerase gamma | 0.00486724 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00486247 |
| SETMAR | SET domain and mariner transposase fusion gene | 0.00485716 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00484046 |
| DCPS | decapping enzyme, scavenger | 0.00483853 |
| ABCC10 | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 | 0.00483663 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | 0.00482814 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.00482365 |
| TBCB | tubulin folding cofactor B | 0.00482327 |
| MORC3 | MORC family CW-type zinc finger 3 | 0.00481932 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | -0.0216056 |
| CA2 | carbonic anhydrase II | -0.0201527 |
| S100P | S100 calcium binding protein P | -0.0160671 |
| CSTA | cystatin A (stefin A) | -0.0158131 |
| CD9 | CD9 molecule | -0.0153464 |
| SIRT3 | sirtuin 3 | -0.0152429 |
| S100A8 | S100 calcium binding protein A8 | -0.0152233 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0149054 |
| PERP | PERP, TP53 apoptosis effector | -0.0145834 |
| S100A10 | S100 calcium binding protein A10 | -0.0143952 |
| XIC | X chromosome inactivation center | -0.0142105 |
| KRT5 | keratin 5, type II | -0.012535 |
| G0S2 | G0/G1 switch 2 | -0.0119316 |
| MAOB | monoamine oxidase B | -0.0118865 |
| KRT14 | keratin 14, type I | -0.0116021 |
| TPD52L1 | tumor protein D52-like 1 | -0.0114416 |
| S100A9 | S100 calcium binding protein A9 | -0.0113269 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.011243 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0110903 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0110054 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.0107909 |
| ANXA2 | annexin A2 | -0.0104961 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0103937 |
| EMP1 | epithelial membrane protein 1 | -0.0103705 |
| KRT19 | keratin 19, type I | -0.0103042 |
| STC2 | stanniocalcin 2 | -0.0101601 |
| EZR | ezrin | -0.0100892 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00999353 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00999345 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00995079 |
| AGR2 | anterior gradient 2 | -0.00989121 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.00974201 |
| KRT15 | keratin 15, type I | -0.00970256 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.0095919 |
| ADM | adrenomedullin | -0.00957606 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00944674 |
| TRIM29 | tripartite motif containing 29 | -0.00943549 |
| MIR22HG | MIR22 host gene | -0.00936214 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00931115 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00918595 |
| AREG | amphiregulin | -0.00915815 |
| PLIN1 | perilipin 1 | -0.00906132 |
| HMOX1 | heme oxygenase 1 | -0.00903895 |
| FGF13 | fibroblast growth factor 13 | -0.00893156 |
| SPRR3 | small proline-rich protein 3 | -0.00892654 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0089261 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00891026 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00870492 |
| CFD | complement factor D (adipsin) | -0.00869577 |
| LTF | lactotransferrin | -0.00866739 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00866195 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00854707 |
| MYBPC1 | myosin binding protein C, slow type | -0.00853439 |
| TEX10 | testis expressed 10 | -0.00850712 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00847438 |
| MFAP3L | microfibrillar-associated protein 3-like | -0.00840229 |
| CST3 | cystatin C | -0.00840217 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00836677 |
| ANXA3 | annexin A3 | -0.00830408 |
| AHNAK | AHNAK nucleoprotein | -0.00824029 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00821097 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.00820109 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00817405 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -0.00812658 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00807317 |
| GRN | granulin | -0.00805796 |
| CDC42SE1 | CDC42 small effector 1 | -0.00805412 |
| OXTR | oxytocin receptor | -0.00799641 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.00788257 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00786741 |
| KRT6A | keratin 6A, type II | -0.0077921 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00777963 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.00777667 |
| RNASET2 | ribonuclease T2 | -0.00768056 |
| CRYAB | crystallin, alpha B | -0.00767092 |
| LYPD1 | LY6/PLAUR domain containing 1 | -0.00762443 |
| FZD7 | frizzled class receptor 7 | -0.007555 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.00749244 |
| CADM1 | cell adhesion molecule 1 | -0.00745156 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0073102 |
| ANXA2P2 | annexin A2 pseudogene 2 | -0.00727741 |
| KRT23 | keratin 23, type I | -0.00721777 |
| FOXG1 | forkhead box G1 | -0.00718911 |
| CYB5R1 | cytochrome b5 reductase 1 | -0.00716559 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0071173 |
| FHL1 | four and a half LIM domains 1 | -0.00709321 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.0070703 |
| TPBG | trophoblast glycoprotein | -0.00705969 |
| CTSZ | cathepsin Z | -0.00704048 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00703156 |
| ERP44 | endoplasmic reticulum protein 44 | -0.00700819 |
| REEP5 | receptor accessory protein 5 | -0.00694997 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00693375 |
| PKP1 | plakophilin 1 | -0.00691841 |
| CDC42 | cell division cycle 42 | -0.0069125 |
| S100A12 | S100 calcium binding protein A12 | -0.00690059 |
| GOLT1B | golgi transport 1B | -0.00688802 |
| UPK1B | uroplakin 1B | -0.00683133 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00682857 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | -0.00680378 |
| ADIRF | adipogenesis regulatory factor | -0.00678256 |
| CLU | clusterin | -0.00675447 |
| NOTCH2 | notch 2 | -0.00674892 |
| TMEM50B | transmembrane protein 50B | -0.00674576 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00674521 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00671482 |
| MPO | myeloperoxidase | -0.00671398 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00671199 |
| OFD1 | oral-facial-digital syndrome 1 | -0.0066806 |
| SLN | sarcolipin | -0.00667535 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00666115 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | -0.00665785 |
| C1S | complement component 1, s subcomponent | -0.00665403 |
| FMOD | fibromodulin | -0.00664293 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00662287 |
| KIAA0040 | KIAA0040 | -0.00662129 |
| TSPYL5 | TSPY-like 5 | -0.00662046 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00660188 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.00659025 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.00658961 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.00657076 |
| NPC1 | Niemann-Pick disease, type C1 | -0.00653905 |
| THBD | thrombomodulin | -0.00653028 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.00648806 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.00647344 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.00645652 |
| ELANE | elastase, neutrophil expressed | -0.0064214 |
| CRCT1 | cysteine-rich C-terminal 1 | -0.00639553 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00639359 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00639324 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00636211 |
| DUSP5 | dual specificity phosphatase 5 | -0.00635022 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | -0.00630247 |
| TP53TG1 | TP53 target 1 (non-protein coding) | -0.00630226 |
| MRPL18 | mitochondrial ribosomal protein L18 | -0.00630092 |
| MYO6 | myosin VI | -0.00629887 |
| NMRK1 | nicotinamide riboside kinase 1 | -0.00627759 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00625309 |
| FOXC1 | forkhead box C1 | -0.00623207 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00622892 |
| GMPR | guanosine monophosphate reductase | -0.00622043 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00620911 |
| OPHN1 | oligophrenin 1 | -0.00620546 |
| IL1RN | interleukin 1 receptor antagonist | -0.006175 |
| RGS2 | regulator of G-protein signaling 2 | -0.00617061 |
| KRT6B | keratin 6B, type II | -0.00616143 |
| PLBD1 | phospholipase B domain containing 1 | -0.00615709 |
| BTG3 | BTG family, member 3 | -0.00613573 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00613494 |
| PON2 | paraoxonase 2 | -0.00612086 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00610764 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00610736 |
| LGALSL | lectin, galactoside-binding-like | -0.00610246 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00608316 |
| CLDN10 | claudin 10 | -0.00607448 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.00606273 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00605359 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00600987 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0060075 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.00600144 |
| LYZ | lysozyme | -0.00599363 |
| KRT17 | keratin 17, type I | -0.00598672 |
| PTS | 6-pyruvoyltetrahydropterin synthase | -0.00598622 |
| DSG3 | desmoglein 3 | -0.00598367 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -0.00596583 |
| ZBTB43 | zinc finger and BTB domain containing 43 | -0.00596058 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00594251 |
| HEBP2 | heme binding protein 2 | -0.00593537 |
| PF4 | platelet factor 4 | -0.0059271 |
| PHIP | pleckstrin homology domain interacting protein | -0.00592648 |
| SIK1 | salt-inducible kinase 1 | -0.00591544 |
| FN1 | fibronectin 1 | -0.00591198 |
| SPRR2B | small proline-rich protein 2B | -0.00588566 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | -0.00586699 |
| EGR1 | early growth response 1 | -0.00586508 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0058386 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00582853 |
| DSP | desmoplakin | -0.0058274 |
| BAG3 | BCL2-associated athanogene 3 | -0.00582561 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.00581845 |
| PCDH9 | protocadherin 9 | -0.00581132 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | -0.00579588 |
| RRAGD | Ras-related GTP binding D | -0.00575795 |
| MT1X | metallothionein 1X | -0.00574892 |
| CA8 | carbonic anhydrase VIII | -0.00574679 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00574249 |
| AZU1 | azurocidin 1 | -0.00573773 |
| PIP4K2C | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma | -0.00573344 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.00573153 |
| CAST | calpastatin | -0.0057305 |
| RGS13 | regulator of G-protein signaling 13 | -0.00572272 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -0.00571803 |
| TWIST1 | twist family bHLH transcription factor 1 | -0.00570878 |
| CCDC6 | coiled-coil domain containing 6 | -0.00569473 |
| NCALD | neurocalcin delta | -0.00568877 |
| MCL1 | myeloid cell leukemia 1 | -0.00568654 |
| TPM4 | tropomyosin 4 | -0.00568444 |
| KRT13 | keratin 13, type I | -0.00567799 |
| MT1H | metallothionein 1H | -0.0056684 |
| RAB9A | RAB9A, member RAS oncogene family | -0.00566095 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00565726 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00564943 |
| DOK5 | docking protein 5 | -0.00564462 |
| APOD | apolipoprotein D | -0.00562782 |
| NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma | -0.00561996 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.00561857 |
| RESF1 | retroelement silencing factor 1 | -0.00560268 |
| RBM47 | RNA binding motif protein 47 | -0.00560102 |
| TP63 | tumor protein p63 | -0.00559992 |
| GSTK1 | glutathione S-transferase kappa 1 | -0.0055946 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00558722 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) | -0.00555692 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.00554541 |
| HSPE1 | heat shock 10kDa protein 1 | -0.00554413 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | -0.00554348 |
| MXRA7 | matrix-remodelling associated 7 | -0.00552831 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00551387 |
| GLDC | glycine dehydrogenase (decarboxylating) | -0.00547783 |
| AK5 | adenylate kinase 5 | -0.00546287 |
| AZIN1 | antizyme inhibitor 1 | -0.00545833 |
| KRT16 | keratin 16, type I | -0.00545708 |
| FAM189A2 | family with sequence similarity 189, member A2 | -0.00544903 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00544884 |
| CYB5R2 | cytochrome b5 reductase 2 | -0.00542671 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00542207 |
| TOB1 | transducer of ERBB2, 1 | -0.00541596 |
| KLF9 | Kruppel-like factor 9 | -0.00541248 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.00538961 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | -0.0053758 |
| KLK6 | kallikrein-related peptidase 6 | -0.00537198 |
| HBD | hemoglobin, delta | -0.00537188 |
| SPRR1B | small proline-rich protein 1B | -0.00536664 |
| TCP1 | t-complex 1 | -0.0053528 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0053364 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -0.00532704 |
| E2F5 | E2F transcription factor 5, p130-binding | -0.00532305 |
| NOTCH2NL | notch 2 N-terminal like | -0.00531485 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00529695 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.00528312 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00526564 |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) | -0.00526318 |
| SCPEP1 | serine carboxypeptidase 1 | -0.00525812 |
| HECA | headcase homolog (Drosophila) | -0.00525305 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | -0.00525205 |
| HBB | hemoglobin, beta | -0.00522973 |
| ITM2C | integral membrane protein 2C | -0.00522295 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.00518992 |
| RAB29 | RAB29, member RAS oncogene family | -0.00516612 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00515413 |
| TASP1 | taspase, threonine aspartase, 1 | -0.00513588 |
