HLA-C Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description major histocompatibility complex, class I, C|HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3107)
External Link http://www.ncbi.nlm.nih.gov/gene/3107
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Genes

731 interacting proteins for HLA-C from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABR active BCR-related
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACAT1 acetyl-CoA acetyltransferase 1
ACOT11 acyl-CoA thioesterase 11
ACSL1 acyl-CoA synthetase long-chain family member 1
ACSL3 acyl-CoA synthetase long-chain family member 3
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTN4 actinin, alpha 4
ADAM10 ADAM metallopeptidase domain 10
ADRB2 adrenoceptor beta 2, surface
ADRM1 adhesion regulating molecule 1
AFG3L2 AFG3-like AAA ATPase 2
AGK acylglycerol kinase
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6
AGPS alkylglycerone phosphate synthase
AHNAK AHNAK nucleoprotein
AIDA axin interactor, dorsalization associated
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AKAP8L A kinase (PRKA) anchor protein 8-like
AKT1S1 AKT1 substrate 1 (proline-rich)
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ANKRD11 ankyrin repeat domain 11
ANXA1 annexin A1
ANXA11 annexin A11
ANXA2 annexin A2
ANXA3 annexin A3
ANXA4 annexin A4
ANXA5 annexin A5
ANXA6 annexin A6
ANXA7 annexin A7
ANXA9 annexin A9
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
AP1M2 adaptor-related protein complex 1, mu 2 subunit
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
APMAP adipocyte plasma membrane associated protein
APP amyloid beta (A4) precursor protein
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARCN1 archain 1
ARF1 ADP-ribosylation factor 1
ARF4 ADP-ribosylation factor 4
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARHGAP35 Rho GTPase activating protein 35
ARHGAP8 Rho GTPase activating protein 8
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARL1 ADP-ribosylation factor-like 1
ARL2 ADP-ribosylation factor-like 2
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ARL8A ADP-ribosylation factor-like 8A
ARL8B ADP-ribosylation factor-like 8B
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD3A ATPase family, AAA domain containing 3A
ATAD3B ATPase family, AAA domain containing 3B
ATG5 autophagy related 5
ATG7 autophagy related 7
ATM ATM serine/threonine kinase
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
ATR ATR serine/threonine kinase
AUP1 ancient ubiquitous protein 1
B2M beta-2-microglobulin
B3GNT1
BATF2 basic leucine zipper transcription factor, ATF-like 2
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCAP29 B-cell receptor-associated protein 29
BCAP31 B-cell receptor-associated protein 31
BCCIP BRCA2 and CDKN1A interacting protein
BET1 Bet1 golgi vesicular membrane trafficking protein
BIN1 bridging integrator 1
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
CAB39 calcium binding protein 39
CACYBP calcyclin binding protein
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CADPS2 Ca++-dependent secretion activator 2
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALR calreticulin
CANX calnexin
CAPRIN1 cell cycle associated protein 1
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CBR1 carbonyl reductase 1
CCDC50 coiled-coil domain containing 50
CCNC cyclin C
CCND1 cyclin D1
CD8A CD8a molecule
CDC25A cell division cycle 25A
CDC42 cell division cycle 42
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDC5L cell division cycle 5-like
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CDK1 cyclin-dependent kinase 1
CDK19 cyclin-dependent kinase 19
CDK4 cyclin-dependent kinase 4
CDK5 cyclin-dependent kinase 5
CENPV centromere protein V
CERS1 ceramide synthase 1
CFL1 cofilin 1 (non-muscle)
CHD3 chromodomain helicase DNA binding protein 3
CHD4 chromodomain helicase DNA binding protein 4
CHMP1A charged multivesicular body protein 1A
CHMP1B charged multivesicular body protein 1B
CHMP2A charged multivesicular body protein 2A
CHMP5 charged multivesicular body protein 5
CHP1 calcineurin-like EF-hand protein 1
CISD2 CDGSH iron sulfur domain 2
CKAP4 cytoskeleton-associated protein 4
CKAP5 cytoskeleton associated protein 5
CLCC1 chloride channel CLIC-like 1
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CLPTM1 cleft lip and palate associated transmembrane protein 1
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CLTA clathrin, light chain A
CLTC clathrin, heavy chain (Hc)
CNN2 calponin 2
CNPY3 canopy FGF signaling regulator 3
COG3 component of oligomeric golgi complex 3
COG4 component of oligomeric golgi complex 4
COMMD3 COMM domain containing 3
COMT catechol-O-methyltransferase
COPA coatomer protein complex, subunit alpha
COPB1 coatomer protein complex, subunit beta 1
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
COPE coatomer protein complex, subunit epsilon
COPG1 coatomer protein complex, subunit gamma 1
COPZ1 coatomer protein complex, subunit zeta 1
COX4I1 cytochrome c oxidase subunit IV isoform 1
CPNE1 copine I
CPNE3 copine III
CSNK1A1 casein kinase 1, alpha 1
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTPS1 CTP synthase 1
CXCR4 chemokine (C-X-C motif) receptor 4
CYB5R3 cytochrome b5 reductase 3
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DCTN2 dynactin 2 (p50)
DCTN3 dynactin 3 (p22)
DDB1 damage-specific DNA binding protein 1, 127kDa
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DGKK diacylglycerol kinase, kappa
DGKQ diacylglycerol kinase, theta 110kDa
DHCR7 7-dehydrocholesterol reductase
DHRS7 dehydrogenase/reductase (SDR family) member 7
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DIAPH1 diaphanous-related formin 1
DIDO1 death inducer-obliterator 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNM2 dynamin 2
DNMBP dynamin binding protein
DOCK1 dedicator of cytokinesis 1
DOCK5 dedicator of cytokinesis 5
DOCK6 dedicator of cytokinesis 6
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
DSC3 desmocollin 3
DST dystonin
DUSP3 dual specificity phosphatase 3
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
ECSIT ECSIT signalling integrator
EHD1 EH-domain containing 1
EHD4 EH-domain containing 4
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
EIF2D eukaryotic translation initiation factor 2D
EIF3F eukaryotic translation initiation factor 3, subunit F
EIF3L eukaryotic translation initiation factor 3, subunit L
ELMO3 engulfment and cell motility 3
EMD emerin
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPHA2 EPH receptor A2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPS8 epidermal growth factor receptor pathway substrate 8
EPS8L2 EPS8-like 2
EPS8L3 EPS8-like 3
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
ERGIC3 ERGIC and golgi 3
ERLEC1 endoplasmic reticulum lectin 1
ERLIN1 ER lipid raft associated 1
ERLIN2 ER lipid raft associated 2
ESYT1 extended synaptotagmin-like protein 1
ESYT2 extended synaptotagmin-like protein 2
EXOC1 exocyst complex component 1
EXOC2 exocyst complex component 2
EXOC3 exocyst complex component 3
EXOC4 exocyst complex component 4
EXOC5 exocyst complex component 5
EXOC6 exocyst complex component 6
EXOC7 exocyst complex component 7
EXOC8 exocyst complex component 8
FAF2 Fas associated factor family member 2
FAM129B family with sequence similarity 129, member B
FAM21A family with sequence similarity 21, member A
FANCD2 Fanconi anemia, complementation group D2
FAR1 fatty acyl CoA reductase 1
FBXO6 F-box protein 6
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FGD4 FYVE, RhoGEF and PH domain containing 4
FLNB filamin B, beta
FLOT1 flotillin 1
FNBP1L formin binding protein 1-like
FRMPD3 FERM and PDZ domain containing 3
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GAA glucosidase, alpha; acid
GANAB glucosidase, alpha; neutral AB
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GDI2 GDP dissociation inhibitor 2
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1
GIGYF2 GRB10 interacting GYF protein 2
GLUD1 glutamate dehydrogenase 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GMPS guanine monphosphate synthase
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNAS GNAS complex locus
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GNPAT glyceronephosphate O-acyltransferase
GOLGA2 golgin A2
GOLIM4 golgi integral membrane protein 4
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GOPC golgi-associated PDZ and coiled-coil motif containing
GOSR1 golgi SNAP receptor complex member 1
GOSR2 golgi SNAP receptor complex member 2
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRB2 growth factor receptor-bound protein 2
GRIPAP1 GRIP1 associated protein 1
GSK3B glycogen synthase kinase 3 beta
GSTM3 glutathione S-transferase mu 3 (brain)
HACD3 3-hydroxyacyl-CoA dehydratase 3
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HAX1 HCLS1 associated protein X-1
HCFC1 host cell factor C1
HEATR1 HEAT repeat containing 1
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HM13 histocompatibility (minor) 13
HOOK1 hook microtubule-tethering protein 1
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12
HSPA1B heat shock 70kDa protein 1B
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTT huntingtin
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ILKAP integrin-linked kinase-associated serine/threonine phosphatase
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
IPCEF1 interaction protein for cytohesin exchange factors 1
IPO7 importin 7
IPO8 importin 8
IQGAP1 IQ motif containing GTPase activating protein 1
IQGAP2 IQ motif containing GTPase activating protein 2
IQGAP3 IQ motif containing GTPase activating protein 3
IST1 increased sodium tolerance 1 homolog (yeast)
ITM2B integral membrane protein 2B
JAK1 Janus kinase 1
KIAA1524 KIAA1524
KIF1A kinesin family member 1A
KIF20B kinesin family member 20B
KIF2A kinesin heavy chain member 2A
KIF4A kinesin family member 4A
KIF5B kinesin family member 5B
KIFC1 kinesin family member C1
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KLC1 kinesin light chain 1
KLC2 kinesin light chain 2
KLC4 kinesin light chain 4
KLHDC2 kelch domain containing 2
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LAMP1 lysosomal-associated membrane protein 1
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LGMN legumain
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LIN7C lin-7 homolog C (C. elegans)
LMAN1 lectin, mannose-binding, 1
LMAN2 lectin, mannose-binding 2
LMBR1 limb development membrane protein 1
LMO7 LIM domain 7
LPCAT1 lysophosphatidylcholine acyltransferase 1
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRP10 low density lipoprotein receptor-related protein 10
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRC59 leucine rich repeat containing 59
LTA4H leukotriene A4 hydrolase
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MDN1 MDN1, midasin homolog (yeast)
MED12 mediator complex subunit 12
MED13 mediator complex subunit 13
MED13L mediator complex subunit 13-like
MED14 mediator complex subunit 14
MED15 mediator complex subunit 15
MED16 mediator complex subunit 16
MED17 mediator complex subunit 17
MED20 mediator complex subunit 20
MED23 mediator complex subunit 23
MED24 mediator complex subunit 24
MED25 mediator complex subunit 25
MED26 mediator complex subunit 26
MED27 mediator complex subunit 27
MED29 mediator complex subunit 29
MED4 mediator complex subunit 4
MED8 mediator complex subunit 8
MED9 mediator complex subunit 9
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MOGS mannosyl-oligosaccharide glucosidase
MON2 MON2 homolog (S. cerevisiae)
MOSPD2 motile sperm domain containing 2
MSN moesin
MTDH metadherin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTX1 metaxin 1
MVP major vault protein
MYH9 myosin, heavy chain 9, non-muscle
MYO7B myosin VIIB
MYOF myoferlin
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NCAPG non-SMC condensin I complex, subunit G
NCLN nicalin
NDNL2 necdin-like 2
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NLRX1 NLR family member X1
NOMO1 NODAL modulator 1
NOP58 NOP58 ribonucleoprotein
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRBP1 nuclear receptor binding protein 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
NSF N-ethylmaleimide-sensitive factor
NUDC nudC nuclear distribution protein
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21
NUP205 nucleoporin 205kDa
NUP210 nucleoporin 210kDa
NUP50 nucleoporin 50kDa
NUP93 nucleoporin 93kDa
OSBP oxysterol binding protein
OSBPL10 oxysterol binding protein-like 10
OSBPL8 oxysterol binding protein-like 8
P4HB prolyl 4-hydroxylase, beta polypeptide
PCBP1 poly(rC) binding protein 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCNA proliferating cell nuclear antigen
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDCD6 programmed cell death 6
PDCD6IP programmed cell death 6 interacting protein
PDS5A PDS5 cohesin associated factor A
PDS5B PDS5 cohesin associated factor B
PGAM5 phosphoglycerate mutase family member 5
PGRMC1 progesterone receptor membrane component 1
PGRMC2 progesterone receptor membrane component 2
PHB prohibitin
PHB2 prohibitin 2
PHGDH phosphoglycerate dehydrogenase
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIKFYVE phosphoinositide kinase, FYVE finger containing
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PITPNA phosphatidylinositol transfer protein, alpha
PITPNB phosphatidylinositol transfer protein, beta
PKN2 protein kinase N2
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G4B phospholipase A2, group IVB (cytosolic)
PLEC plectin
PLEK2 pleckstrin 2
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLEKHA7 pleckstrin homology domain containing, family A member 7
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
PLIN3 perilipin 3
PLS1 plastin 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
PON2 paraoxonase 2
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1R7 protein phosphatase 1, regulatory subunit 7
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP5C protein phosphatase 5, catalytic subunit
PPP6C protein phosphatase 6, catalytic subunit
PPT1 palmitoyl-protein thioesterase 1
PRAF2 PRA1 domain family, member 2
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKCD protein kinase C, delta
PRKCSH protein kinase C substrate 80K-H
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT1 protein arginine methyltransferase 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSEN1 presenilin 1
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PTGES2 prostaglandin E synthase 2
PTK2 protein tyrosine kinase 2
PTOV1 prostate tumor overexpressed 1
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PYCR2 pyrroline-5-carboxylate reductase family, member 2
RAB10 RAB10, member RAS oncogene family
RAB11A RAB11A, member RAS oncogene family
RAB11B RAB11B, member RAS oncogene family
RAB13 RAB13, member RAS oncogene family
RAB14 RAB14, member RAS oncogene family
RAB17 RAB17, member RAS oncogene family
RAB18 RAB18, member RAS oncogene family
RAB19 RAB19, member RAS oncogene family
RAB1A RAB1A, member RAS oncogene family
RAB21 RAB21, member RAS oncogene family
RAB23 RAB23, member RAS oncogene family
RAB2A RAB2A, member RAS oncogene family
RAB33B RAB33B, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RAB43 RAB43, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAB8A RAB8A, member RAS oncogene family
RAB9A RAB9A, member RAS oncogene family
RABAC1 Rab acceptor 1 (prenylated)
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RABL3 RAB, member of RAS oncogene family-like 3
RABL6 RAB, member RAS oncogene family-like 6
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RACGAP1 Rac GTPase activating protein 1
RAD23B RAD23 homolog B (S. cerevisiae)
RAI14 retinoic acid induced 14
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALB v-ral simian leukemia viral oncogene homolog B
RAN RAN, member RAS oncogene family
RANBP1 RAN binding protein 1
RANBP17 RAN binding protein 17
RANGAP1 Ran GTPase activating protein 1
RAP1A RAP1A, member of RAS oncogene family
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RAP2B RAP2B, member of RAS oncogene family
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RASL11A RAS-like, family 11, member A
RBX1 ring-box 1, E3 ubiquitin protein ligase
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RDH13 retinol dehydrogenase 13 (all-trans/9-cis)
RFC3 replication factor C (activator 1) 3, 38kDa
RHEB Ras homolog enriched in brain
RHOA ras homolog family member A
RHOT1 ras homolog family member T1
RHOT2 ras homolog family member T2
RHPN2 rhophilin, Rho GTPase binding protein 2
RIF1 replication timing regulatory factor 1
RIMS1 regulating synaptic membrane exocytosis 1
RINT1 RAD50 interactor 1
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RNF139 ring finger protein 139
RNF213 ring finger protein 213
RPL14 ribosomal protein L14
RPL3 ribosomal protein L3
RPN1 ribophorin I
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RSF1 remodeling and spacing factor 1
RSU1 Ras suppressor protein 1
RTN3 reticulon 3
RTN4 reticulon 4
RUVBL1 RuvB-like AAA ATPase 1
SACM1L SAC1 suppressor of actin mutations 1-like (yeast)
SAR1A secretion associated, Ras related GTPase 1A
SARS seryl-tRNA synthetase
SCAMP1 secretory carrier membrane protein 1
SCAMP2 secretory carrier membrane protein 2
SCAMP3 secretory carrier membrane protein 3
SCARB2 scavenger receptor class B, member 2
SCCPDH saccharopine dehydrogenase (putative)
SCFD1 sec1 family domain containing 1
SCFD2 sec1 family domain containing 2
SCO2 SCO2 cytochrome c oxidase assembly protein
SCP2 sterol carrier protein 2
SDF2 stromal cell-derived factor 2
SDF2L1 stromal cell-derived factor 2-like 1
SDF4 stromal cell derived factor 4
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SEC23A Sec23 homolog A (S. cerevisiae)
SEC31A SEC31 homolog A (S. cerevisiae)
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SEC61B Sec61 beta subunit
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEPT10 septin 10
SEPT11 septin 11
SEPT14 septin 14
SEPT2 septin 2
SEPT7 septin 7
SEPT8 septin 8
SEPT9 septin 9
SFT2D3 SFT2 domain containing 3
SGK3 serum/glucocorticoid regulated kinase family, member 3
SHB Src homology 2 domain containing adaptor protein B
SIGMAR1 sigma non-opioid intracellular receptor 1
SKP1 S-phase kinase-associated protein 1
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC30A9 solute carrier family 30 (zinc transporter), member 9
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SMC1A structural maintenance of chromosomes 1A
SMC2 structural maintenance of chromosomes 2
SMC3 structural maintenance of chromosomes 3
SMC4 structural maintenance of chromosomes 4
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SNAP23 synaptosomal-associated protein, 23kDa
SNF8 SNF8, ESCRT-II complex subunit
SNPH syntaphilin
SNX1 sorting nexin 1
SNX12 sorting nexin 12
SNX13 sorting nexin 13
SNX14 sorting nexin 14
SNX2 sorting nexin 2
SNX3 sorting nexin 3
SNX4 sorting nexin 4
SNX5 sorting nexin 5
SPAG5 sperm associated antigen 5
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPTBN1 spectrin, beta, non-erythrocytic 1
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRP68 signal recognition particle 68kDa
SRP72 signal recognition particle 72kDa
SRPRB signal recognition particle receptor, B subunit
STAG1 stromal antigen 1
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STAMBPL1 STAM binding protein-like 1
STARD10 StAR-related lipid transfer (START) domain containing 10
STARD5 StAR-related lipid transfer (START) domain containing 5
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STEAP3 STEAP family member 3, metalloreductase
STOML2 stomatin (EPB72)-like 2
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
STX12 syntaxin 12
STX16 syntaxin 16
STX17 syntaxin 17
STX18 syntaxin 18
STX3 syntaxin 3
STX4 syntaxin 4
STX5 syntaxin 5
STXBP2 syntaxin binding protein 2
STXBP3 syntaxin binding protein 3
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit
SUMO1 small ubiquitin-like modifier 1
SUN1 Sad1 and UNC84 domain containing 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYK spleen tyrosine kinase
SYNE2 spectrin repeat containing, nuclear envelope 2
SYNJ2BP synaptojanin 2 binding protein
TAGLN2 transgelin 2
TANK TRAF family member-associated NFKB activator
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TBC1D15 TBC1 domain family, member 15
TBC1D4 TBC1 domain family, member 4
TBCA tubulin folding cofactor A
TBCD tubulin folding cofactor D
TEC tec protein tyrosine kinase
TFRC transferrin receptor
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TJP1 tight junction protein 1
TJP2 tight junction protein 2
TLN1 talin 1
TLN2 talin 2
TM9SF1 transmembrane 9 superfamily member 1
TM9SF4 transmembrane 9 superfamily protein member 4
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMED9 transmembrane emp24 protein transport domain containing 9
TMEM161A transmembrane protein 161A
TMX1 thioredoxin-related transmembrane protein 1
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNPO1 transportin 1
TOM1 target of myb1 (chicken)
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOR1AIP1 torsin A interacting protein 1
TP53BP2 tumor protein p53 binding protein 2
TPX2 TPX2, microtubule-associated
TRAFD1 TRAF-type zinc finger domain containing 1
TRAP1 TNF receptor-associated protein 1
TRAPPC3 trafficking protein particle complex 3
TRAPPC4 trafficking protein particle complex 4
TRIM24 tripartite motif containing 24
TRIM28 tripartite motif containing 28
TRIP13 thyroid hormone receptor interactor 13
TRRAP transformation/transcription domain-associated protein
TTI1 TELO2 interacting protein 1
TUBA1B tubulin, alpha 1b
TUBA1C tubulin, alpha 1c
TUBB4B tubulin, beta 4B class IVb
TUFM Tu translation elongation factor, mitochondrial
TXLNA taxilin alpha
TXLNG taxilin gamma
UBC ubiquitin C
UBE3C ubiquitin protein ligase E3C
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
UHRF1 ubiquitin-like with PHD and ring finger domains 1
ULK3 unc-51 like kinase 3
UNC45A unc-45 homolog A (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
URGCP upregulator of cell proliferation
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae)
USH1C Usher syndrome 1C (autosomal recessive, severe)
USP8 ubiquitin specific peptidase 8
USP9X ubiquitin specific peptidase 9, X-linked
VAC14 Vac14 homolog (S. cerevisiae)
VAMP3 vesicle-associated membrane protein 3
VAMP7 vesicle-associated membrane protein 7
VAMP8 vesicle-associated membrane protein 8
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VASP vasodilator-stimulated phosphoprotein
VAT1 vesicle amine transport 1
VAV2 vav 2 guanine nucleotide exchange factor
VCP valosin containing protein
VDAC1 voltage-dependent anion channel 1
VDAC2 voltage-dependent anion channel 2
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae)
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae)
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS33B vacuolar protein sorting 33 homolog B (yeast)
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae)
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)
VTA1 vesicle (multivesicular body) trafficking 1
VTI1A vesicle transport through interaction with t-SNAREs 1A
WASF2 WAS protein family, member 2
WASL Wiskott-Aldrich syndrome-like
WRNIP1 Werner helicase interacting protein 1
XPO1 exportin 1
XPO4 exportin 4
XPO5 exportin 5
XPO7 exportin 7
XPOT exportin, tRNA
YBX1 Y box binding protein 1
YME1L1 YME1-like 1 ATPase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZFPL1 zinc finger protein-like 1
ZFYVE1 zinc finger, FYVE domain containing 1
ZW10 zw10 kinetochore protein
ZWILCH zwilch kinetochore protein
ZWINT ZW10 interacting kinetochore protein