| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | major histocompatibility complex, class II, DM alpha|HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3108) |
| External Link | https://ncbi.nlm.nih.gov/gene/3108 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the HLA-DMA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RGCC | regulator of cell cycle | 0.012641 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0115944 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0114875 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0113986 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0106889 |
| FBXO11 | F-box protein 11 | 0.0106739 |
| TFF1 | trefoil factor 1 | 0.0105899 |
| DAXX | death-domain associated protein | 0.0104069 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.010098 |
| PTK2 | protein tyrosine kinase 2 | 0.0100607 |
| S100P | S100 calcium binding protein P | 0.010057 |
| KRT13 | keratin 13, type I | 0.00997839 |
| S100A7 | S100 calcium binding protein A7 | 0.00989933 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00989282 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00977862 |
| CSTA | cystatin A (stefin A) | 0.00958486 |
| TNC | tenascin C | 0.00957338 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00945408 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00938483 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00928739 |
| C3 | complement component 3 | 0.00923094 |
| EMP1 | epithelial membrane protein 1 | 0.00888944 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00882619 |
| TSPAN8 | tetraspanin 8 | 0.00877376 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00872458 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00871741 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00871274 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00868635 |
| ITGA6 | integrin, alpha 6 | 0.00864951 |
| S100A2 | S100 calcium binding protein A2 | 0.00861435 |
| KRT5 | keratin 5, type II | 0.00848203 |
| FABP7 | fatty acid binding protein 7, brain | 0.00840586 |
| NRN1 | neuritin 1 | 0.00837993 |
| PRAME | preferentially expressed antigen in melanoma | 0.00833199 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.0083017 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00823765 |
| HAT1 | histone acetyltransferase 1 | 0.00820764 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00807479 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00806694 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00801901 |
| GPX2 | glutathione peroxidase 2 | 0.00800609 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00790843 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00788004 |
| MAL | mal, T-cell differentiation protein | 0.00787896 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00787128 |
| STOM | stomatin | 0.00786399 |
| ANXA1 | annexin A1 | 0.00783213 |
| COG7 | component of oligomeric golgi complex 7 | 0.00764269 |
| MSMB | microseminoprotein, beta- | 0.00759248 |
| TRIM16 | tripartite motif containing 16 | 0.00756211 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.00751677 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 0.00749038 |
| NCK1 | NCK adaptor protein 1 | 0.00746878 |
| MSX1 | msh homeobox 1 | 0.00742314 |
| C1S | complement component 1, s subcomponent | 0.00730802 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00729832 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0072791 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00727276 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00722198 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00721571 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.00719406 |
| TUBB2A | tubulin, beta 2A class IIa | 0.0071756 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00717476 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00713405 |
| FMO5 | flavin containing monooxygenase 5 | 0.00712383 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00711501 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00707372 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.00706762 |
| AK4 | adenylate kinase 4 | 0.00705836 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0070524 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00704348 |
| MREG | melanoregulin | 0.00704153 |
| IRS2 | insulin receptor substrate 2 | 0.00703537 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00700914 |
| MLF1 | myeloid leukemia factor 1 | 0.00696359 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | 0.00695658 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.00691403 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00690344 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00689328 |
| EMP2 | epithelial membrane protein 2 | 0.00680666 |
| CD83 | CD83 molecule | 0.00677283 |
| SPRR3 | small proline-rich protein 3 | 0.00675418 |
| RBBP4 | retinoblastoma binding protein 4 | 0.00672221 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00668607 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.00665498 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00665486 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00664791 |
| PER2 | period circadian clock 2 | 0.00664438 |
| CHN1 | chimerin 1 | 0.00660592 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00658749 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00657571 |
| SDC2 | syndecan 2 | 0.00656403 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00655719 |
| COPS7A | COP9 signalosome subunit 7A | 0.00655273 |
| GPM6B | glycoprotein M6B | 0.00653825 |
| DEFB1 | defensin, beta 1 | 0.00651315 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | 0.00651024 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00650764 |
| BTG3 | BTG family, member 3 | 0.00650307 |
| CES1 | carboxylesterase 1 | 0.00649389 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.00648371 |
| TSPAN7 | tetraspanin 7 | 0.0064771 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00642534 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.006396 |
| AGTR1 | angiotensin II receptor, type 1 | 0.00637989 |
| CANX | calnexin | 0.00636316 |
| ELOVL2 | ELOVL fatty acid elongase 2 | 0.00631781 |
| IFNGR1 | interferon gamma receptor 1 | 0.00631464 |
| PLLP | plasmolipin | 0.0062913 |
| TBX3 | T-box 3 | 0.00629115 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00627991 |
| AGPS | alkylglycerone phosphate synthase | 0.00622657 |
| LDLR | low density lipoprotein receptor | 0.00619399 |
| MYO1C | myosin IC | 0.00619138 |
| TRAM1 | translocation associated membrane protein 1 | 0.00617185 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00614964 |
| MANSC1 | MANSC domain containing 1 | 0.00613998 |
| ATF3 | activating transcription factor 3 | 0.0061286 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00611866 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00611391 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.00610888 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.00608329 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | 0.00608234 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00607543 |
| PLAT | plasminogen activator, tissue | 0.00606363 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00606355 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00605204 |
| FOLR1 | folate receptor 1 (adult) | 0.00605063 |
| TFDP1 | transcription factor Dp-1 | 0.00604839 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00604178 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00603956 |
| PTCH1 | patched 1 | 0.00602687 |
| NTS | neurotensin | 0.00601965 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00596226 |
| TSPAN1 | tetraspanin 1 | 0.00595494 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00595449 |
| GPC3 | glypican 3 | 0.00591728 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00587844 |
| KYNU | kynureninase | 0.00587177 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00586587 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0058419 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.0058328 |
| NLGN4X | neuroligin 4, X-linked | 0.00581682 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.00581401 |
| CSPG5 | chondroitin sulfate proteoglycan 5 (neuroglycan C) | 0.00580597 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00580021 |
| PEG3 | paternally expressed 3 | 0.00577877 |
| TOX3 | TOX high mobility group box family member 3 | 0.00575056 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00573558 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.00573524 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00572189 |
| KRT6A | keratin 6A, type II | 0.00572077 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00571189 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00569733 |
| SYNGR3 | synaptogyrin 3 | 0.0056701 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00566472 |
| TPM2 | tropomyosin 2 (beta) | 0.00566422 |
| ASPH | aspartate beta-hydroxylase | 0.00562623 |
| AZIN1 | antizyme inhibitor 1 | 0.00562508 |
| IQCG | IQ motif containing G | 0.00561487 |
| AREG | amphiregulin | 0.00561321 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.00561242 |
| PRNP | prion protein | 0.00560482 |
| GYPC | glycophorin C (Gerbich blood group) | 0.00560364 |
| EPCAM | epithelial cell adhesion molecule | 0.00559728 |
| HSBP1 | heat shock factor binding protein 1 | 0.00555548 |
| TMEM100 | transmembrane protein 100 | 0.00553258 |
| MYO1B | myosin IB | 0.00553145 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00552105 |
| LHFP | lipoma HMGIC fusion partner | 0.00551645 |
| KRT81 | keratin 81, type II | 0.0055155 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00550628 |
| TRIM29 | tripartite motif containing 29 | 0.00550506 |
| CFI | complement factor I | 0.00549396 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00548923 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 0.00546953 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00546651 |
| KLHL23 | kelch-like family member 23 | 0.00546345 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.00546201 |
| AOC1 | amine oxidase, copper containing 1 | 0.00546144 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.00545331 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0054475 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.00544559 |
| SYK | spleen tyrosine kinase | 0.00544127 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.00544018 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00543932 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | 0.0054323 |
| KRT15 | keratin 15, type I | 0.00542027 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00541439 |
| IL6ST | interleukin 6 signal transducer | 0.00540734 |
| EDN3 | endothelin 3 | 0.00539599 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.00539319 |
| DAZAP2 | DAZ associated protein 2 | 0.00538511 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00536455 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.00536091 |
| BAALC | brain and acute leukemia, cytoplasmic | 0.00535812 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00535303 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0053528 |
| PSCA | prostate stem cell antigen | 0.00535095 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | 0.00534879 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00533469 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 0.00533187 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F | 0.00531687 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00530158 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00528787 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | 0.00527566 |
| PHF11 | PHD finger protein 11 | 0.00525475 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00524156 |
| TMEM47 | transmembrane protein 47 | 0.00523923 |
| JAK1 | Janus kinase 1 | 0.00521754 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00521306 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00521081 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.00520409 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.00519949 |
| MATR3 | matrin 3 | 0.00519694 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00517422 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00517312 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00515348 |
| IL1RN | interleukin 1 receptor antagonist | 0.00515206 |
| RBMX | RNA binding motif protein, X-linked | 0.00514519 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.00514455 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00514044 |
| PRMT1 | protein arginine methyltransferase 1 | 0.00512952 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.00511147 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.00509619 |
| S100A9 | S100 calcium binding protein A9 | 0.00508953 |
| S100B | S100 calcium binding protein B | 0.00508406 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00508053 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00505691 |
| OPHN1 | oligophrenin 1 | 0.00505238 |
| IFI44L | interferon-induced protein 44-like | 0.00503769 |
| ADCY3 | adenylate cyclase 3 | 0.00503459 |
| LAMB3 | laminin, beta 3 | 0.00500241 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.00499672 |
| PBK | PDZ binding kinase | 0.00498524 |
| TRIM14 | tripartite motif containing 14 | 0.00498178 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00497708 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00497668 |
| KIF5C | kinesin family member 5C | 0.00497667 |
| CD34 | CD34 molecule | 0.00497377 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0049729 |
| ABLIM1 | actin binding LIM protein 1 | 0.00497016 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00496576 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.00495336 |
| MPO | myeloperoxidase | 0.00494109 |
| LASP1 | LIM and SH3 protein 1 | 0.00493777 |
| CD99 | CD99 molecule | 0.00493613 |
| CAST | calpastatin | 0.00493582 |
| KLK6 | kallikrein-related peptidase 6 | 0.00493209 |
| EGR2 | early growth response 2 | 0.00492983 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0169833 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -0.0139812 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.0116906 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0116816 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0115524 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0106267 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.0105662 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.009379 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00924051 |
| TCTA | T-cell leukemia translocation altered | -0.0089578 |
| SIRT3 | sirtuin 3 | -0.00879143 |
| HOPX | HOP homeobox | -0.00849533 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00844128 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00828101 |
| DAPK1 | death-associated protein kinase 1 | -0.00826061 |
| MT1X | metallothionein 1X | -0.00825324 |
| NOTCH2NL | notch 2 N-terminal like | -0.00824665 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00817483 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.00802857 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0079528 |
| HBD | hemoglobin, delta | -0.00791555 |
| EXOSC4 | exosome component 4 | -0.00791422 |
| CCNA2 | cyclin A2 | -0.0078378 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00781888 |
| RGS4 | regulator of G-protein signaling 4 | -0.00772568 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00770845 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00766235 |
| STXBP2 | syntaxin binding protein 2 | -0.0075753 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.00749769 |
| BCL2L1 | BCL2-like 1 | -0.00748021 |
| RTN2 | reticulon 2 | -0.00726693 |
| RXRA | retinoid X receptor, alpha | -0.00724998 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00723047 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00720062 |
| ASS1 | argininosuccinate synthase 1 | -0.00716032 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00712301 |
| CREB1 | cAMP responsive element binding protein 1 | -0.00711163 |
| BGN | biglycan | -0.00706916 |
| TSPAN4 | tetraspanin 4 | -0.00702683 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | -0.00701105 |
| TGFB1 | transforming growth factor, beta 1 | -0.00690895 |
| NVL | nuclear VCP-like | -0.00681678 |
| PAEP | progestagen-associated endometrial protein | -0.00675979 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00672017 |
| CD163 | CD163 molecule | -0.00662562 |
| SRGN | serglycin | -0.00660054 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.00659993 |
| CLIC3 | chloride intracellular channel 3 | -0.0065975 |
| MT1G | metallothionein 1G | -0.00651859 |
| NXN | nucleoredoxin | -0.006508 |
| NKG7 | natural killer cell granule protein 7 | -0.00644823 |
| MMP2 | matrix metallopeptidase 2 | -0.00640854 |
| NOTCH2 | notch 2 | -0.00639815 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00638782 |
| PDHX | pyruvate dehydrogenase complex, component X | -0.00637974 |
| EFHD1 | EF-hand domain family, member D1 | -0.00627436 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00623709 |
| BSG | basigin (Ok blood group) | -0.00622599 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00622217 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0062173 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.0062111 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00621029 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00619445 |
| AMOTL2 | angiomotin like 2 | -0.00616828 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00615083 |
| MT1H | metallothionein 1H | -0.00613042 |
| PLXND1 | plexin D1 | -0.00610231 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00609242 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00604235 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00601404 |
| PLXNB2 | plexin B2 | -0.00600106 |
| CAPRIN2 | caprin family member 2 | -0.00599744 |
| DENND1B | DENN/MADD domain containing 1B | -0.00599565 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.00599223 |
| PNPLA6 | patatin-like phospholipase domain containing 6 | -0.00596859 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | -0.00595105 |
| NEFM | neurofilament, medium polypeptide | -0.00595075 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.0059178 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00591073 |
| CA12 | carbonic anhydrase XII | -0.0058886 |
| RAB8A | RAB8A, member RAS oncogene family | -0.00580286 |
| GOLGA8H | golgin A8 family, member H | -0.00578217 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 | -0.00577067 |
| ZNF544 | zinc finger protein 544 | -0.00575957 |
| ANAPC2 | anaphase promoting complex subunit 2 | -0.00575715 |
| TLK2 | tousled-like kinase 2 | -0.0057422 |
| STK38 | serine/threonine kinase 38 | -0.00572577 |
| GNLY | granulysin | -0.00572168 |
| MT1E | metallothionein 1E | -0.00571974 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00567701 |
| CRYAB | crystallin, alpha B | -0.00566011 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.00563669 |
| PLD3 | phospholipase D family, member 3 | -0.00563593 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.00562096 |
| CCDC92 | coiled-coil domain containing 92 | -0.00562056 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00561524 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00558667 |
| ZNF580 | zinc finger protein 580 | -0.00556676 |
| GATA6 | GATA binding protein 6 | -0.00556623 |
| PLIN2 | perilipin 2 | -0.0055662 |
| CD9 | CD9 molecule | -0.00554006 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.005495 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00547995 |
| LAT2 | linker for activation of T cells family, member 2 | -0.0054344 |
| MLPH | melanophilin | -0.00541939 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | -0.00540987 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00540965 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00540064 |
| CCR2 | chemokine (C-C motif) receptor 2 | -0.00540032 |
| RTL8A | retrotransposon Gag like 8A | -0.00539754 |
| KCTD14 | potassium channel tetramerization domain containing 14 | -0.00539672 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | -0.00539167 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00538472 |
| CDC20 | cell division cycle 20 | -0.00537944 |
| CKM | creatine kinase, muscle | -0.00537518 |
| BRD4 | bromodomain containing 4 | -0.00536473 |
| CRCT1 | cysteine-rich C-terminal 1 | -0.00535967 |
| EML3 | echinoderm microtubule associated protein like 3 | -0.00533742 |
| RTL8C | retrotransposon Gag like 8C | -0.00532483 |
| MAGEA3 | melanoma antigen family A3 | -0.00529451 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.005281 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0052808 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.00527287 |
| RANGAP1 | Ran GTPase activating protein 1 | -0.00526986 |
| CTBP2 | C-terminal binding protein 2 | -0.00526012 |
| TXLNA | taxilin alpha | -0.00525238 |
| RBM34 | RNA binding motif protein 34 | -0.00525056 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa | -0.00524944 |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 | -0.00524085 |
| AAMDC | adipogenesis associated, Mth938 domain containing | -0.00523482 |
| SOCS1 | suppressor of cytokine signaling 1 | -0.0052248 |
| STAB1 | stabilin 1 | -0.0052177 |
| DGCR8 | DGCR8 microprocessor complex subunit | -0.00521218 |
| TYMP | thymidine phosphorylase | -0.0052102 |
| SMAD7 | SMAD family member 7 | -0.0052055 |
| NID2 | nidogen 2 (osteonidogen) | -0.00520465 |
| TMEM176B | transmembrane protein 176B | -0.00519964 |
| EPS15 | epidermal growth factor receptor pathway substrate 15 | -0.00519063 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | -0.00515851 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.00515548 |
| BAD | BCL2-associated agonist of cell death | -0.00515384 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00514731 |
| CD8A | CD8a molecule | -0.0051382 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.00513607 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 | -0.00512713 |
| PLEC | plectin | -0.00512064 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | -0.00512037 |
| BCHE | butyrylcholinesterase | -0.00510874 |
| SDCBP | syndecan binding protein (syntenin) | -0.00509989 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00509902 |
| FSTL1 | follistatin-like 1 | -0.0050923 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00506381 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00506353 |
| AEBP1 | AE binding protein 1 | -0.00505285 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | -0.0050445 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | -0.00503174 |
| GPAA1 | glycosylphosphatidylinositol anchor attachment 1 | -0.00502986 |
| CST1 | cystatin SN | -0.00502566 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00499303 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0049804 |
| SMYD3 | SET and MYND domain containing 3 | -0.00496274 |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 | -0.0049495 |
| WDR7 | WD repeat domain 7 | -0.00493012 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -0.00491505 |
| CDC34 | cell division cycle 34 | -0.00491455 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -0.00491054 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.00490655 |
| ACAA2 | acetyl-CoA acyltransferase 2 | -0.00490173 |
| MAGED1 | melanoma antigen family D1 | -0.00488591 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00488303 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | -0.00488265 |
| SPATA20 | spermatogenesis associated 20 | -0.00488244 |
| CCS | copper chaperone for superoxide dismutase | -0.00488047 |
| SST | somatostatin | -0.00487402 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | -0.00486178 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.00485253 |
| NUMA1 | nuclear mitotic apparatus protein 1 | -0.00484754 |
| TES | testin LIM domain protein | -0.00484535 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | -0.00482754 |
| TSPAN12 | tetraspanin 12 | -0.00481092 |
| MEST | mesoderm specific transcript | -0.0047913 |
| MYO1F | myosin IF | -0.00477618 |
| MZB1 | marginal zone B and B1 cell-specific protein | -0.00475912 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.00475079 |
| TRIM37 | tripartite motif containing 37 | -0.0047383 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00473558 |
| FZD2 | frizzled class receptor 2 | -0.00473517 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | -0.0047341 |
| CTH | cystathionine gamma-lyase | -0.00473317 |
| GALC | galactosylceramidase | -0.00473269 |
| VEGFC | vascular endothelial growth factor C | -0.00473022 |
| ANGPTL4 | angiopoietin-like 4 | -0.00471246 |
| TPP1 | tripeptidyl peptidase I | -0.00471166 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00470922 |
| APMAP | adipocyte plasma membrane associated protein | -0.00469517 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00469274 |
| BMP2 | bone morphogenetic protein 2 | -0.00469118 |
| ECM1 | extracellular matrix protein 1 | -0.004691 |
| IRF4 | interferon regulatory factor 4 | -0.00467523 |
| TRIM8 | tripartite motif containing 8 | -0.00467024 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00466461 |
| CCL15 | chemokine (C-C motif) ligand 15 | -0.00466101 |
| WASL | Wiskott-Aldrich syndrome-like | -0.00465902 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | -0.00465807 |
| ABCC10 | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 | -0.00465646 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00465587 |
| RRBP1 | ribosome binding protein 1 | -0.0046502 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00464357 |
| SIN3B | SIN3 transcription regulator family member B | -0.0046374 |
| PCP4 | Purkinje cell protein 4 | -0.00463605 |
| CLDN3 | claudin 3 | -0.00463397 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00462291 |
| LMNB2 | lamin B2 | -0.00462079 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00461815 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00460559 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00460493 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00460449 |
| AIM2 | absent in melanoma 2 | -0.00459379 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) | -0.00459245 |
| ATG2A | autophagy related 2A | -0.0045739 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00456166 |
| CTSA | cathepsin A | -0.00455164 |
| NCDN | neurochondrin | -0.0045249 |
| ITGA8 | integrin, alpha 8 | -0.00451757 |
| CD14 | CD14 molecule | -0.0045064 |
| RNF115 | ring finger protein 115 | -0.00450553 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -0.00450419 |
| IVD | isovaleryl-CoA dehydrogenase | -0.00449355 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.00449018 |
| SLC46A3 | solute carrier family 46, member 3 | -0.00448836 |
| MED13 | mediator complex subunit 13 | -0.0044863 |
| SLITRK5 | SLIT and NTRK-like family, member 5 | -0.00447036 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00445628 |
| CYB5R1 | cytochrome b5 reductase 1 | -0.00445399 |
| SOCS2 | suppressor of cytokine signaling 2 | -0.00444827 |
| KRT1 | keratin 1, type II | -0.00444042 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | -0.00443995 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 | -0.00443193 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 | -0.00443084 |
| KAT2B | K(lysine) acetyltransferase 2B | -0.00442802 |
| ALAS2 | 5'-aminolevulinate synthase 2 | -0.00441705 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 | -0.00440244 |
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | -0.00439814 |
| FN1 | fibronectin 1 | -0.00439541 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00436868 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00436724 |
| MAPK7 | mitogen-activated protein kinase 7 | -0.00436592 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00436424 |
