| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | major histocompatibility complex, class II, DM beta|HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3109) |
| External Link | https://ncbi.nlm.nih.gov/gene/3109 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the HLA-DMB gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | 0.0199776 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0174884 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.0125289 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0118885 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0112882 |
| PCDH9 | protocadherin 9 | 0.00919511 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00918435 |
| NBEA | neurobeachin | 0.00908374 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00898596 |
| BEX1 | brain expressed, X-linked 1 | 0.00889961 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00882853 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00881642 |
| RTN2 | reticulon 2 | 0.00878788 |
| NEFH | neurofilament, heavy polypeptide | 0.00871272 |
| MATN2 | matrilin 2 | 0.00870225 |
| HBB | hemoglobin, beta | 0.00869721 |
| NAV3 | neuron navigator 3 | 0.0085958 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00856826 |
| ADIRF | adipogenesis regulatory factor | 0.00852959 |
| RGS5 | regulator of G-protein signaling 5 | 0.00818292 |
| DCLK1 | doublecortin-like kinase 1 | 0.00809432 |
| NTS | neurotensin | 0.00794343 |
| CTSG | cathepsin G | 0.00787655 |
| RTN1 | reticulon 1 | 0.00786463 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.00785529 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00782334 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00778579 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00772148 |
| NID2 | nidogen 2 (osteonidogen) | 0.00758287 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.00750848 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00748914 |
| SRGN | serglycin | 0.00741011 |
| ANK2 | ankyrin 2, neuronal | 0.00726306 |
| PLPP3 | phospholipid phosphatase 3 | 0.00720904 |
| PKP4 | plakophilin 4 | 0.00717329 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00712439 |
| EHD2 | EH-domain containing 2 | 0.00711034 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00706863 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00692668 |
| ITGA7 | integrin, alpha 7 | 0.00692533 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00692025 |
| NES | nestin | 0.00691558 |
| TNC | tenascin C | 0.00688435 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 | 0.00687194 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00670482 |
| G0S2 | G0/G1 switch 2 | 0.00669567 |
| CP | ceruloplasmin (ferroxidase) | 0.00667643 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00665473 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00662153 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.00656892 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 0.00656398 |
| DIXDC1 | DIX domain containing 1 | 0.00656397 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00647652 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00644833 |
| TXLNA | taxilin alpha | 0.00644204 |
| RAB13 | RAB13, member RAS oncogene family | 0.00641904 |
| OPHN1 | oligophrenin 1 | 0.00638639 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 0.00636948 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00636312 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00635557 |
| MFSD10 | major facilitator superfamily domain containing 10 | 0.00635399 |
| NID1 | nidogen 1 | 0.00634579 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.00633532 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0063277 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00629344 |
| FASN | fatty acid synthase | 0.00628248 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.00627698 |
| IPO13 | importin 13 | 0.00627506 |
| CA12 | carbonic anhydrase XII | 0.0062595 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.00622767 |
| STC1 | stanniocalcin 1 | 0.006222 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00620676 |
| HOXC10 | homeobox C10 | 0.00620061 |
| COLEC12 | collectin sub-family member 12 | 0.00618201 |
| PFKM | phosphofructokinase, muscle | 0.00617577 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00617382 |
| LEPR | leptin receptor | 0.00616766 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00614718 |
| ADCY1 | adenylate cyclase 1 (brain) | 0.00613384 |
| TSPAN12 | tetraspanin 12 | 0.00605018 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00604839 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00602833 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00602033 |
| PEG10 | paternally expressed 10 | 0.0059142 |
| ELANE | elastase, neutrophil expressed | 0.00587917 |
| TRRAP | transformation/transcription domain-associated protein | 0.00587045 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00584978 |
| AUTS2 | autism susceptibility candidate 2 | 0.00583024 |
| HOXB2 | homeobox B2 | 0.00582605 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00581182 |
| CPE | carboxypeptidase E | 0.00580149 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00580104 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00578316 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00577909 |
| IRS1 | insulin receptor substrate 1 | 0.00571933 |
| CS | citrate synthase | 0.00570341 |
| C7 | complement component 7 | 0.00569662 |
| CLIP3 | CAP-GLY domain containing linker protein 3 | 0.00568928 |
| SYT1 | synaptotagmin I | 0.00566435 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00565878 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.00562299 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.00562073 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00561592 |
| GPR183 | G protein-coupled receptor 183 | 0.00559634 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00556623 |
| RAI2 | retinoic acid induced 2 | 0.00554537 |
| DPP4 | dipeptidyl-peptidase 4 | 0.00553825 |
| REPIN1 | replication initiator 1 | 0.00553233 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.0055318 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00551968 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.00551522 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | 0.00550883 |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) | 0.00549922 |
| HMGB3 | high mobility group box 3 | 0.0054982 |
| AGRN | agrin | 0.00547743 |
| PTN | pleiotrophin | 0.00546891 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 0.00546754 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.00544787 |
| MAOA | monoamine oxidase A | 0.00538889 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.00536233 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00536103 |
| TSPAN7 | tetraspanin 7 | 0.00534002 |
| AZU1 | azurocidin 1 | 0.00533523 |
| HCRT | hypocretin (orexin) neuropeptide precursor | 0.00532608 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.00531136 |
| OGN | osteoglycin | 0.00529504 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0052767 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | 0.00524648 |
| TMEM131L | transmembrane 131 like | 0.00523987 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.00523854 |
| EFNB2 | ephrin-B2 | 0.0052359 |
| ISYNA1 | inositol-3-phosphate synthase 1 | 0.00521894 |
| NOTCH3 | notch 3 | 0.00520844 |
| SMTN | smoothelin | 0.0052023 |
| TRIM28 | tripartite motif containing 28 | 0.00519593 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.00518425 |
| FXYD1 | FXYD domain containing ion transport regulator 1 | 0.00517019 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.00512557 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00512218 |
| KIAA0930 | KIAA0930 | 0.00512026 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00512024 |
| NEFM | neurofilament, medium polypeptide | 0.00511307 |
| DMPK | dystrophia myotonica-protein kinase | 0.00510024 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | 0.00509992 |
| CENPE | centromere protein E, 312kDa | 0.00506773 |
| CLGN | calmegin | 0.0050587 |
| NOVA1 | neuro-oncological ventral antigen 1 | 0.00505711 |
| SALL2 | spalt-like transcription factor 2 | 0.00504877 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.00504693 |
| ZNF395 | zinc finger protein 395 | 0.00503412 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | 0.00502833 |
| GAL | galanin/GMAP prepropeptide | 0.00502815 |
| CBX5 | chromobox homolog 5 | 0.00502772 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.0050221 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.00501322 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 0.005005 |
| ADGRL4 | adhesion G protein-coupled receptor L4 | 0.00500462 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00499261 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | 0.00499179 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | 0.00499134 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.00497907 |
| SHOX2 | short stature homeobox 2 | 0.00497198 |
| CD38 | CD38 molecule | 0.00497088 |
| CNN3 | calponin 3, acidic | 0.00495896 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.00494394 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00494061 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00493419 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00493412 |
| GALC | galactosylceramidase | 0.00492422 |
| PDZD8 | PDZ domain containing 8 | 0.00490244 |
| CAV2 | caveolin 2 | 0.00489883 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00486152 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00485844 |
| AGTR1 | angiotensin II receptor, type 1 | 0.00485294 |
| FAM193A | family with sequence similarity 193, member A | 0.00485227 |
| FAM149A | family with sequence similarity 149, member A | 0.00484059 |
| MEIS2 | Meis homeobox 2 | 0.004836 |
| CLIC2 | chloride intracellular channel 2 | 0.00483246 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 0.00483089 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.00482938 |
| DIPK1A | divergent protein kinase domain 1A | 0.00482725 |
| XK | X-linked Kx blood group | 0.0048256 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00482358 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00479875 |
| PRPF8 | pre-mRNA processing factor 8 | 0.00479508 |
| GSTA1 | glutathione S-transferase alpha 1 | 0.00477654 |
| PDGFD | platelet derived growth factor D | 0.00476451 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.00474551 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00474317 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | 0.00473946 |
| MAP1A | microtubule-associated protein 1A | 0.0047379 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00473188 |
| CFD | complement factor D (adipsin) | 0.00472289 |
| DACH1 | dachshund family transcription factor 1 | 0.00472026 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00471251 |
| NANOG | Nanog homeobox | 0.00470182 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.00469385 |
| SPAG5 | sperm associated antigen 5 | 0.00468773 |
| TENM3 | teneurin transmembrane protein 3 | 0.00468581 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.00468264 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | 0.00467254 |
| APOD | apolipoprotein D | 0.00464831 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00464743 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | 0.00464191 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.0046314 |
| CYBRD1 | cytochrome b reductase 1 | 0.00462401 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.00462023 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0046176 |
| SUOX | sulfite oxidase | 0.0046136 |
| INA | internexin neuronal intermediate filament protein, alpha | 0.00461129 |
| DMAC2 | distal membrane arm assembly component 2 | 0.00460734 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.00459643 |
| RCAN2 | regulator of calcineurin 2 | 0.00459506 |
| CLC | Charcot-Leyden crystal galectin | 0.00458994 |
| CRYM | crystallin, mu | 0.00458219 |
| PCOLCE | procollagen C-endopeptidase enhancer | 0.00458163 |
| ACO1 | aconitase 1, soluble | 0.00457839 |
| TBC1D16 | TBC1 domain family, member 16 | 0.0045761 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00457426 |
| PCGF2 | polycomb group ring finger 2 | 0.00457113 |
| PLK1 | polo-like kinase 1 | 0.00456554 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.00455781 |
| SDC3 | syndecan 3 | 0.0045466 |
| GTPBP1 | GTP binding protein 1 | 0.00454125 |
| ARG2 | arginase 2 | 0.00453817 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.00453588 |
| JAG2 | jagged 2 | 0.00452104 |
| PNKP | polynucleotide kinase 3'-phosphatase | 0.00452039 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.00450843 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00450291 |
| DPAGT1 | dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) | 0.00449541 |
| PHKA2 | phosphorylase kinase, alpha 2 (liver) | 0.00449433 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00449021 |
| FLNC | filamin C, gamma | 0.00448636 |
| ETV5 | ets variant 5 | 0.00448488 |
| ZNF580 | zinc finger protein 580 | 0.00448304 |
| MID1 | midline 1 | 0.00447427 |
| PLCL1 | phospholipase C-like 1 | 0.00447192 |
| ESYT1 | extended synaptotagmin-like protein 1 | 0.00445805 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.00445458 |
| TP73-AS1 | TP73 antisense RNA 1 | 0.00444583 |
| NPY | neuropeptide Y | 0.00444376 |
| SAP30 | Sin3A-associated protein, 30kDa | 0.00443429 |
| ELAC2 | elaC ribonuclease Z 2 | 0.00443353 |
| VARS | valyl-tRNA synthetase | 0.00443146 |
| COL3A1 | collagen, type III, alpha 1 | 0.00442831 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.00442497 |
| SMS | spermine synthase | 0.00442415 |
| FLT1 | fms-related tyrosine kinase 1 | 0.00441757 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00440462 |
| Symbol | Name | Standardized Value |
|---|---|---|
| STXBP2 | syntaxin binding protein 2 | -0.0147868 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0117981 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.0113938 |
| FABP7 | fatty acid binding protein 7, brain | -0.0113384 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0106034 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0103227 |
| INHBA | inhibin, beta A | -0.0100064 |
| FERMT1 | fermitin family member 1 | -0.00977647 |
| TSPAN4 | tetraspanin 4 | -0.00972621 |
| RBM34 | RNA binding motif protein 34 | -0.00963753 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00953091 |
| ITGA6 | integrin, alpha 6 | -0.00943033 |
| COPS7A | COP9 signalosome subunit 7A | -0.00941283 |
| TNNC1 | troponin C type 1 (slow) | -0.00940097 |
| MMP11 | matrix metallopeptidase 11 | -0.00938436 |
| CLEC2B | C-type lectin domain family 2, member B | -0.0093655 |
| S100P | S100 calcium binding protein P | -0.00926335 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00908388 |
| COQ8A | coenzyme Q8A | -0.00901426 |
| CLTB | clathrin, light chain B | -0.008994 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00870653 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0086746 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.00845591 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00844537 |
| PALLD | palladin, cytoskeletal associated protein | -0.00834393 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00831399 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00830943 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00817381 |
| ODAM | odontogenic, ameloblast asssociated | -0.00815412 |
| HOPX | HOP homeobox | -0.00814285 |
| TPM4 | tropomyosin 4 | -0.00814222 |
| STK10 | serine/threonine kinase 10 | -0.00809877 |
| KRT19 | keratin 19, type I | -0.00808088 |
| GNLY | granulysin | -0.00804003 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00785257 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.00784659 |
| ANXA3 | annexin A3 | -0.00778958 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00778674 |
| KLF2 | Kruppel-like factor 2 | -0.00777867 |
| EPCAM | epithelial cell adhesion molecule | -0.00772529 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00771218 |
| DSP | desmoplakin | -0.00765482 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0076182 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00757201 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.0074777 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | -0.00746845 |
| TSPAN13 | tetraspanin 13 | -0.00743483 |
| SPRR1B | small proline-rich protein 1B | -0.00742748 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.0073923 |
| S100A7 | S100 calcium binding protein A7 | -0.00737324 |
| S100A2 | S100 calcium binding protein A2 | -0.00730274 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00723164 |
| KLF6 | Kruppel-like factor 6 | -0.0072031 |
| RNF130 | ring finger protein 130 | -0.00719467 |
| CALML5 | calmodulin-like 5 | -0.00714413 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.0071042 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00709617 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00709243 |
| IL32 | interleukin 32 | -0.00709209 |
| NAGK | N-acetylglucosamine kinase | -0.00708536 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00707046 |
| KLK10 | kallikrein-related peptidase 10 | -0.0070654 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0070635 |
| DSG3 | desmoglein 3 | -0.00705772 |
| RPS26 | ribosomal protein S26 | -0.00691333 |
| ERGIC2 | ERGIC and golgi 2 | -0.00691321 |
| BAX | BCL2-associated X protein | -0.00687603 |
| TEX10 | testis expressed 10 | -0.00686846 |
| PODXL | podocalyxin-like | -0.00686846 |
| ABLIM1 | actin binding LIM protein 1 | -0.00678138 |
| F2R | coagulation factor II (thrombin) receptor | -0.00676694 |
| CCNA2 | cyclin A2 | -0.00669141 |
| PERP | PERP, TP53 apoptosis effector | -0.0066816 |
| DSC2 | desmocollin 2 | -0.0066049 |
| MCL1 | myeloid cell leukemia 1 | -0.00652719 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | -0.00650121 |
| CAPRIN1 | cell cycle associated protein 1 | -0.00649337 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00647078 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00646849 |
| C1S | complement component 1, s subcomponent | -0.0064646 |
| MMP7 | matrix metallopeptidase 7 | -0.00644746 |
| ECM1 | extracellular matrix protein 1 | -0.00642653 |
| PLSCR3 | phospholipid scramblase 3 | -0.00641607 |
| IPO7 | importin 7 | -0.00639689 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00636848 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | -0.00629937 |
| S100A12 | S100 calcium binding protein A12 | -0.00627997 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.00623311 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | -0.0062273 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00621155 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | -0.00620284 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | -0.00620236 |
| REEP5 | receptor accessory protein 5 | -0.00616093 |
| KRT6A | keratin 6A, type II | -0.00616036 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00613216 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -0.00611465 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00611333 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | -0.00610803 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00605335 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | -0.00601815 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.00598375 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | -0.00596344 |
| LSP1 | lymphocyte-specific protein 1 | -0.00594354 |
| LXN | latexin | -0.00589255 |
| SPRR2B | small proline-rich protein 2B | -0.00588112 |
| PRKCQ | protein kinase C, theta | -0.00585003 |
| TRH | thyrotropin-releasing hormone | -0.00583108 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00582614 |
| ZWILCH | zwilch kinetochore protein | -0.00582463 |
| EMP1 | epithelial membrane protein 1 | -0.00581216 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00576915 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.00576532 |
| CEL | carboxyl ester lipase | -0.00575037 |
| CST1 | cystatin SN | -0.00574641 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00573767 |
| CCN2 | cellular communication network factor 2 | -0.00572399 |
| ACP5 | acid phosphatase 5, tartrate resistant | -0.00571992 |
| RHOB | ras homolog family member B | -0.00570823 |
| EHF | ets homologous factor | -0.00569197 |
| FAM162A | family with sequence similarity 162, member A | -0.00568287 |
| CCNE2 | cyclin E2 | -0.005657 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.00565347 |
| CTTN | cortactin | -0.00564656 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | -0.0056455 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00564481 |
| S100A10 | S100 calcium binding protein A10 | -0.005643 |
| CD52 | CD52 molecule | -0.00563263 |
| MAGEA3 | melanoma antigen family A3 | -0.00563154 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00562463 |
| SCEL | sciellin | -0.00562378 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00559421 |
| CD14 | CD14 molecule | -0.00559102 |
| FYB1 | FYN binding protein 1 | -0.00558559 |
| OSTF1 | osteoclast stimulating factor 1 | -0.00556915 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.00556573 |
| CBFB | core-binding factor, beta subunit | -0.00554922 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | -0.00553865 |
| LAMC2 | laminin, gamma 2 | -0.0055262 |
| BTG3 | BTG family, member 3 | -0.00549304 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | -0.00549143 |
| NCF4 | neutrophil cytosolic factor 4, 40kDa | -0.00549046 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) | -0.00548684 |
| COL10A1 | collagen, type X, alpha 1 | -0.00547651 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00547279 |
| RGS10 | regulator of G-protein signaling 10 | -0.005465 |
| SPRR1A | small proline-rich protein 1A | -0.00545446 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | -0.00545283 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00545257 |
| ITK | IL2-inducible T-cell kinase | -0.0054518 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0054505 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00544559 |
| MAGEA12 | melanoma antigen family A12 | -0.00542111 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00542057 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00539026 |
| KIAA0125 | KIAA0125 | -0.00537223 |
| HCRTR1 | hypocretin (orexin) receptor 1 | -0.00535689 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00535539 |
| CD163 | CD163 molecule | -0.00534771 |
| CSTB | cystatin B (stefin B) | -0.00531019 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00530413 |
| DNASE2 | deoxyribonuclease II, lysosomal | -0.00530232 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00527963 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00527823 |
| LPIN1 | lipin 1 | -0.00525167 |
| GPX1 | glutathione peroxidase 1 | -0.00522157 |
| ANXA6 | annexin A6 | -0.00521229 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00520182 |
| TPM3 | tropomyosin 3 | -0.00519388 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | -0.00519214 |
| FST | follistatin | -0.00519123 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00517035 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00516735 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.00515219 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00514418 |
| IL1A | interleukin 1, alpha | -0.00513797 |
| GPM6B | glycoprotein M6B | -0.00513142 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00513075 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.00512733 |
| NMRK1 | nicotinamide riboside kinase 1 | -0.00511875 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00511567 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -0.00511118 |
| FADD | Fas (TNFRSF6)-associated via death domain | -0.0051108 |
| PLAUR | plasminogen activator, urokinase receptor | -0.00510596 |
| GPR171 | G protein-coupled receptor 171 | -0.00509484 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00509078 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.005078 |
| LTF | lactotransferrin | -0.00507774 |
| GTF2H1 | general transcription factor IIH, polypeptide 1, 62kDa | -0.0050719 |
| SP110 | SP110 nuclear body protein | -0.00506894 |
| CAPN3 | calpain 3, (p94) | -0.00506472 |
| STX7 | syntaxin 7 | -0.00505687 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | -0.00505589 |
| AK1 | adenylate kinase 1 | -0.00505437 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.00505193 |
| SFTPD | surfactant protein D | -0.00504731 |
| RIOK3 | RIO kinase 3 | -0.00503544 |
| CRCT1 | cysteine-rich C-terminal 1 | -0.00503534 |
| PTK2 | protein tyrosine kinase 2 | -0.00503211 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.00503037 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | -0.00502954 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00498927 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.00498194 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | -0.00497998 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00497891 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.00496461 |
| FAM120A | family with sequence similarity 120A | -0.00495879 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00495629 |
| MXRA5 | matrix-remodelling associated 5 | -0.00492764 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | -0.00492339 |
| NCF2 | neutrophil cytosolic factor 2 | -0.00491941 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.00491421 |
| ADCY7 | adenylate cyclase 7 | -0.00490761 |
| PTER | phosphotriesterase related | -0.00490687 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) | -0.00490384 |
| SPRR3 | small proline-rich protein 3 | -0.00490165 |
| GNAS | GNAS complex locus | -0.00487831 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00485003 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0048442 |
| LY96 | lymphocyte antigen 96 | -0.00483863 |
| KRT6B | keratin 6B, type II | -0.00483531 |
| CLIC3 | chloride intracellular channel 3 | -0.00482115 |
| RIN3 | Ras and Rab interactor 3 | -0.00480052 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.00479899 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.00478471 |
| RHCG | Rh family, C glycoprotein | -0.00478469 |
| ATP5F1C | ATP synthase F1 subunit gamma | -0.00476818 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.00476297 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.00474532 |
| CD48 | CD48 molecule | -0.00471189 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00471081 |
| TMEM9B | TMEM9 domain family, member B | -0.00470525 |
| SPHK1 | sphingosine kinase 1 | -0.00469898 |
| CTSV | cathepsin V | -0.00469157 |
| PLAU | plasminogen activator, urokinase | -0.00468317 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.00468203 |
| TWF2 | twinfilin actin binding protein 2 | -0.0046774 |
| DSG1 | desmoglein 1 | -0.00467099 |
| TDRD7 | tudor domain containing 7 | -0.00466603 |
| MAGT1 | magnesium transporter 1 | -0.0046591 |
| IL6ST | interleukin 6 signal transducer | -0.00465772 |
| FOXA2 | forkhead box A2 | -0.00465258 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00465076 |
| FAM102A | family with sequence similarity 102, member A | -0.00464758 |
| FPGS | folylpolyglutamate synthase | -0.00464677 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.00464437 |
| CYTH4 | cytohesin 4 | -0.00464436 |
| ZNF91 | zinc finger protein 91 | -0.00463855 |
| TTN | titin | -0.0046256 |
| RNFT1 | ring finger protein, transmembrane 1 | -0.0046071 |
