| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | major histocompatibility complex, class II, DO alpha|HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3111) |
| External Link | https://ncbi.nlm.nih.gov/gene/3111 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the HLA-DOA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BMP4 | bone morphogenetic protein 4 | 0.0182562 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.0143265 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.0138671 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0134189 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.0131682 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0131489 |
| A2M | alpha-2-macroglobulin | 0.0127809 |
| METRN | meteorin, glial cell differentiation regulator | 0.012059 |
| NES | nestin | 0.0120294 |
| DPYD | dihydropyrimidine dehydrogenase | 0.011581 |
| TCTA | T-cell leukemia translocation altered | 0.0107945 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.010683 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.0102783 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00992567 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00988934 |
| ZIC1 | Zic family member 1 | 0.0098224 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00971328 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00970347 |
| GLUL | glutamate-ammonia ligase | 0.00966637 |
| CD200 | CD200 molecule | 0.0096611 |
| S100A7 | S100 calcium binding protein A7 | 0.00965132 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0096386 |
| CHI3L2 | chitinase 3-like 2 | 0.009501 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00942379 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00936711 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00934025 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00919151 |
| CDC20 | cell division cycle 20 | 0.00914449 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00903324 |
| BEX1 | brain expressed, X-linked 1 | 0.00897538 |
| PLN | phospholamban | 0.00897278 |
| RGS5 | regulator of G-protein signaling 5 | 0.00896873 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00896191 |
| TNC | tenascin C | 0.00891449 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00887655 |
| DIPK1A | divergent protein kinase domain 1A | 0.00886335 |
| ISL1 | ISL LIM homeobox 1 | 0.00877563 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00872975 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00862124 |
| TGM2 | transglutaminase 2 | 0.00859455 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.00859454 |
| TSPAN7 | tetraspanin 7 | 0.00856237 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00848744 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | 0.00848634 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00847863 |
| FXYD1 | FXYD domain containing ion transport regulator 1 | 0.0083731 |
| PLPP3 | phospholipid phosphatase 3 | 0.00827025 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00825364 |
| MGP | matrix Gla protein | 0.00821278 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | 0.00818622 |
| CLIP3 | CAP-GLY domain containing linker protein 3 | 0.00815898 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.0080998 |
| NDRG2 | NDRG family member 2 | 0.00804424 |
| CNN1 | calponin 1, basic, smooth muscle | 0.00802737 |
| WDR7 | WD repeat domain 7 | 0.00798137 |
| BCL2 | B-cell CLL/lymphoma 2 | 0.00797737 |
| MEIS2 | Meis homeobox 2 | 0.00796374 |
| PTN | pleiotrophin | 0.00796301 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00795268 |
| ADORA2B | adenosine A2b receptor | 0.00794624 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00793791 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 0.00791706 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00791441 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00786218 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00785153 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.00783857 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 | 0.00779053 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00778315 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00777044 |
| FABP7 | fatty acid binding protein 7, brain | 0.00775558 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.00775144 |
| NCAM1 | neural cell adhesion molecule 1 | 0.00769512 |
| LPXN | leupaxin | 0.00764278 |
| DZIP1 | DAZ interacting zinc finger protein 1 | 0.00763283 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.00762506 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00760533 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.00753112 |
| FAIM2 | Fas apoptotic inhibitory molecule 2 | 0.00752077 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.00751756 |
| B4GALT6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | 0.00749061 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.0074859 |
| SNX7 | sorting nexin 7 | 0.00746258 |
| XPO7 | exportin 7 | 0.00738051 |
| PDLIM3 | PDZ and LIM domain 3 | 0.00736921 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00735608 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.0073492 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00734309 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.00729827 |
| PLAT | plasminogen activator, tissue | 0.00729598 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00728962 |
| STK26 | serine/threonine protein kinase 26 | 0.0072605 |
| OLFM4 | olfactomedin 4 | 0.00723885 |
| TMEM255A | transmembrane protein 255A | 0.0072251 |
| RGCC | regulator of cell cycle | 0.0071839 |
| RCAN2 | regulator of calcineurin 2 | 0.00717703 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00714867 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00713025 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00711844 |
| LRP1 | low density lipoprotein receptor-related protein 1 | 0.00708626 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00705096 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | 0.00704415 |
| RAB27A | RAB27A, member RAS oncogene family | 0.00703319 |
| OGN | osteoglycin | 0.0070004 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) | 0.00698009 |
| SHOX2 | short stature homeobox 2 | 0.0069367 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.00691376 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00687259 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00686373 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.00685528 |
| CD177 | CD177 molecule | 0.00681798 |
| SYT11 | synaptotagmin XI | 0.00680907 |
| CNN3 | calponin 3, acidic | 0.00678793 |
| FCGBP | Fc fragment of IgG binding protein | 0.00677237 |
| NFASC | neurofascin | 0.00676368 |
| LAMA4 | laminin, alpha 4 | 0.00675282 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00674576 |
| GYPC | glycophorin C (Gerbich blood group) | 0.00674363 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00673714 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.00671634 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00671153 |
| ANXA6 | annexin A6 | 0.00663932 |
| PLP1 | proteolipid protein 1 | 0.00660402 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00658871 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00658811 |
| SV2A | synaptic vesicle glycoprotein 2A | 0.00656776 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | 0.00654193 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00648665 |
| LMOD1 | leiomodin 1 (smooth muscle) | 0.00647774 |
| COCH | cochlin | 0.00647472 |
| HNMT | histamine N-methyltransferase | 0.00647203 |
| DCHS1 | dachsous cadherin-related 1 | 0.00647199 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00646172 |
| TMEM176A | transmembrane protein 176A | 0.00645025 |
| CCL15 | chemokine (C-C motif) ligand 15 | 0.00644502 |
| PLSCR4 | phospholipid scramblase 4 | 0.00644051 |
| SALL2 | spalt-like transcription factor 2 | 0.00642067 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | 0.0063705 |
| KRT13 | keratin 13, type I | 0.00636656 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | 0.00634991 |
| ARHGEF9 | Cdc42 guanine nucleotide exchange factor (GEF) 9 | 0.00633931 |
| NCAN | neurocan | 0.00633327 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.00631557 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.00630809 |
| CLCA4 | chloride channel accessory 4 | 0.00629095 |
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.00628661 |
| PER2 | period circadian clock 2 | 0.00628383 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00627859 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00627379 |
| NRCAM | neuronal cell adhesion molecule | 0.00625786 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | 0.00624122 |
| CA14 | carbonic anhydrase XIV | 0.0062263 |
| CES1 | carboxylesterase 1 | 0.00619958 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.00618651 |
| NOP53 | NOP53 ribosome biogenesis factor | 0.00618013 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.00617634 |
| S100B | S100 calcium binding protein B | 0.00616388 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.00615833 |
| NID1 | nidogen 1 | 0.00615518 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00614375 |
| TIE1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.00614117 |
| EDNRB | endothelin receptor type B | 0.00613296 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00613116 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 0.00612803 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | 0.00612356 |
| ADGRA2 | adhesion G protein-coupled receptor A2 | 0.00612254 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00611167 |
| TYRP1 | tyrosinase-related protein 1 | 0.00609833 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00609766 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00608441 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.00607494 |
| TMEM47 | transmembrane protein 47 | 0.00606183 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00605002 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00604053 |
| ANK2 | ankyrin 2, neuronal | 0.00604013 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00603932 |
| STK38L | serine/threonine kinase 38 like | 0.00603123 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 | 0.00602501 |
| CDO1 | cysteine dioxygenase type 1 | 0.00601786 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00600862 |
| FHOD3 | formin homology 2 domain containing 3 | 0.00598049 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.00595913 |
| EHBP1 | EH domain binding protein 1 | 0.00595788 |
| SPRR3 | small proline-rich protein 3 | 0.00595457 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.00593219 |
| SALL1 | spalt-like transcription factor 1 | 0.00593036 |
| CTSH | cathepsin H | 0.00591287 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 0.00590515 |
| DENND2B | DENN domain containing 2B | 0.00588872 |
| GPX2 | glutathione peroxidase 2 | 0.00588183 |
| GSDME | gasdermin E | 0.00587646 |
| FAR2 | fatty acyl CoA reductase 2 | 0.00583269 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00582395 |
| MLEC | malectin | 0.00582204 |
| SCG5 | secretogranin V | 0.00579802 |
| KIFAP3 | kinesin-associated protein 3 | 0.00579339 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.00578527 |
| TMEM35 | transmembrane protein 35 | 0.00576361 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00575544 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.00573725 |
| PMP22 | peripheral myelin protein 22 | 0.00573594 |
| DES | desmin | 0.00571859 |
| COLEC12 | collectin sub-family member 12 | 0.00571385 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00570101 |
| PRKCA | protein kinase C, alpha | 0.00568532 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00568043 |
| COL3A1 | collagen, type III, alpha 1 | 0.00567827 |
| APOC2 | apolipoprotein C-II | 0.00567657 |
| NELL1 | NEL-like 1 (chicken) | 0.00567404 |
| PCOLCE | procollagen C-endopeptidase enhancer | 0.00565121 |
| CASQ2 | calsequestrin 2 (cardiac muscle) | 0.00561294 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.0056089 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.00560656 |
| NEBL | nebulette | 0.00559953 |
| FMO5 | flavin containing monooxygenase 5 | 0.00559798 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.00559227 |
| NMB | neuromedin B | 0.00558959 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | 0.00558125 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0055803 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.0055696 |
| KLF9 | Kruppel-like factor 9 | 0.00556241 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.00555615 |
| MAOB | monoamine oxidase B | 0.00554699 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0055419 |
| ANGPT1 | angiopoietin 1 | 0.00553662 |
| GLOD4 | glyoxalase domain containing 4 | 0.00552978 |
| GPR183 | G protein-coupled receptor 183 | 0.00552483 |
| RAPSN | receptor-associated protein of the synapse | 0.00552466 |
| CERS6 | ceramide synthase 6 | 0.00551021 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00550062 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00548611 |
| GPC4 | glypican 4 | 0.00547333 |
| AOX1 | aldehyde oxidase 1 | 0.00545032 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.00544699 |
| ZNF22 | zinc finger protein 22 | 0.00544269 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00544086 |
| PRMT1 | protein arginine methyltransferase 1 | 0.00543355 |
| TPX2 | TPX2, microtubule-associated | 0.00542718 |
| CASC3 | cancer susceptibility candidate 3 | 0.00540474 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00540076 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00538827 |
| MAB21L1 | mab-21-like 1 (C. elegans) | 0.00538238 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.00538171 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.00537881 |
| LDB2 | LIM domain binding 2 | 0.00536404 |
| MME | membrane metallo-endopeptidase | 0.00536169 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00535131 |
| RPA2 | replication protein A2, 32kDa | 0.00535 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00531842 |
| TLK2 | tousled-like kinase 2 | 0.00531763 |
| ELMO1 | engulfment and cell motility 1 | 0.00531553 |
| Symbol | Name | Standardized Value |
|---|---|---|
| STXBP2 | syntaxin binding protein 2 | -0.0170757 |
| ASS1 | argininosuccinate synthase 1 | -0.0159246 |
| ANXA3 | annexin A3 | -0.015242 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0148354 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0145954 |
| CA2 | carbonic anhydrase II | -0.0132001 |
| KRT7 | keratin 7, type II | -0.0131872 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.0121715 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0117748 |
| TUFT1 | tuftelin 1 | -0.0114722 |
| TOB1 | transducer of ERBB2, 1 | -0.0114574 |
| MAGEA3 | melanoma antigen family A3 | -0.0108991 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0107924 |
| KRT17 | keratin 17, type I | -0.0107667 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.0107233 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -0.0104637 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.0103483 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.010243 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0101314 |
| TFRC | transferrin receptor | -0.0101248 |
| PERP | PERP, TP53 apoptosis effector | -0.00999769 |
| DSP | desmoplakin | -0.00994453 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00989174 |
| ALAS2 | 5'-aminolevulinate synthase 2 | -0.00979912 |
| HBD | hemoglobin, delta | -0.00971567 |
| NOTCH2NL | notch 2 N-terminal like | -0.0095716 |
| TSPAN13 | tetraspanin 13 | -0.00955563 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00953815 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.0095164 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00945932 |
| RHOF | ras homolog family member F (in filopodia) | -0.00936266 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) | -0.00933808 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00922614 |
| MAP7 | microtubule-associated protein 7 | -0.00916582 |
| LYZ | lysozyme | -0.00908863 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00892334 |
| HECA | headcase homolog (Drosophila) | -0.00873597 |
| NXN | nucleoredoxin | -0.00870794 |
| VNN1 | vanin 1 | -0.00866443 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00861513 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00856299 |
| IL18 | interleukin 18 | -0.00848623 |
| EZR | ezrin | -0.00846924 |
| CLDN1 | claudin 1 | -0.00838151 |
| MECOM | MDS1 and EVI1 complex locus | -0.00825655 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00824196 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.00814484 |
| TXNIP | thioredoxin interacting protein | -0.00811947 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | -0.00804307 |
| S100P | S100 calcium binding protein P | -0.00803894 |
| PRDX2 | peroxiredoxin 2 | -0.00799028 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00797632 |
| HBB | hemoglobin, beta | -0.00796364 |
| LY75 | lymphocyte antigen 75 | -0.00791205 |
| EPCAM | epithelial cell adhesion molecule | -0.00789374 |
| GSTM1 | glutathione S-transferase mu 1 | -0.00782821 |
| MAGEA1 | melanoma antigen family A1 | -0.00781649 |
| ZNF721 | zinc finger protein 721 | -0.00781423 |
| SDC4 | syndecan 4 | -0.00779186 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00777832 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | -0.00771689 |
| ZNF160 | zinc finger protein 160 | -0.00771343 |
| PRSS21 | protease, serine, 21 (testisin) | -0.00768081 |
| NNMT | nicotinamide N-methyltransferase | -0.00766284 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.00763236 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00762922 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00761832 |
| TPD52L1 | tumor protein D52-like 1 | -0.00759367 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00757252 |
| ITK | IL2-inducible T-cell kinase | -0.00753583 |
| WWC1 | WW and C2 domain containing 1 | -0.00752514 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00749615 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.00746312 |
| UPK1B | uroplakin 1B | -0.00733655 |
| CTSV | cathepsin V | -0.00730138 |
| PLAU | plasminogen activator, urokinase | -0.00729815 |
| NDE1 | nudE neurodevelopment protein 1 | -0.00727572 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00720486 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00717318 |
| MAGEA12 | melanoma antigen family A12 | -0.00713399 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | -0.00711584 |
| GOLM1 | golgi membrane protein 1 | -0.00710886 |
| S100A12 | S100 calcium binding protein A12 | -0.00708196 |
| PRKCZ | protein kinase C, zeta | -0.00705627 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00703876 |
| HCRT | hypocretin (orexin) neuropeptide precursor | -0.00701123 |
| EVI2A | ecotropic viral integration site 2A | -0.0070006 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | -0.00697934 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00696612 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0069413 |
| NPTX1 | neuronal pentraxin I | -0.00691978 |
| RUNX3 | runt-related transcription factor 3 | -0.00690027 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00689485 |
| KLK5 | kallikrein-related peptidase 5 | -0.00688169 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00688103 |
| AHSP | alpha hemoglobin stabilizing protein | -0.0068794 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.00685182 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00685099 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00684602 |
| MORC4 | MORC family CW-type zinc finger 4 | -0.00684268 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00683755 |
| E2F3 | E2F transcription factor 3 | -0.00682021 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.0068197 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.00681082 |
| FOLR1 | folate receptor 1 (adult) | -0.00678574 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00677893 |
| TGFB1 | transforming growth factor, beta 1 | -0.00676385 |
| S100A8 | S100 calcium binding protein A8 | -0.00674224 |
| PTK2 | protein tyrosine kinase 2 | -0.00670371 |
| ZNF91 | zinc finger protein 91 | -0.00669801 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00668818 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00667972 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | -0.00665856 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00664424 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | -0.0066412 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00662786 |
| IL32 | interleukin 32 | -0.00661262 |
| PIP4K2C | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma | -0.00657888 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.00657524 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.0065544 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0065455 |
| CTSC | cathepsin C | -0.00653988 |
| TMEM134 | transmembrane protein 134 | -0.0065229 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00651558 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.00651139 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00650547 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00649697 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00649357 |
| GAS6 | growth arrest-specific 6 | -0.00648398 |
| KLF6 | Kruppel-like factor 6 | -0.00648169 |
| MXD4 | MAX dimerization protein 4 | -0.00645301 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00644309 |
| CLIC3 | chloride intracellular channel 3 | -0.00638719 |
| IL10RA | interleukin 10 receptor, alpha | -0.00637896 |
| RRAGA | Ras-related GTP binding A | -0.00637085 |
| PF4 | platelet factor 4 | -0.00636739 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.00636469 |
| GNLY | granulysin | -0.00636284 |
| CDCA4 | cell division cycle associated 4 | -0.00636138 |
| MAGEB2 | melanoma antigen family B2 | -0.00634321 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | -0.00633421 |
| CHN1 | chimerin 1 | -0.00631603 |
| TAOK1 | TAO kinase 1 | -0.0063035 |
| YIPF3 | Yip1 domain family, member 3 | -0.00629222 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00627996 |
| KRT8 | keratin 8, type II | -0.00626269 |
| DLX2 | distal-less homeobox 2 | -0.00626197 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00625563 |
| SLC38A2 | solute carrier family 38, member 2 | -0.00624604 |
| NINJ2 | ninjurin 2 | -0.006242 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.00623313 |
| LAMA5 | laminin, alpha 5 | -0.006197 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.006172 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.006169 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00615182 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.0061357 |
| RASA4 | RAS p21 protein activator 4 | -0.00609323 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.00607416 |
| SQSTM1 | sequestosome 1 | -0.00607331 |
| S100A9 | S100 calcium binding protein A9 | -0.00607092 |
| CALML5 | calmodulin-like 5 | -0.00606584 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00605753 |
| MUC16 | mucin 16, cell surface associated | -0.00605357 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00601759 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00600924 |
| FBXW12 | F-box and WD repeat domain containing 12 | -0.00598305 |
| PDGFC | platelet derived growth factor C | -0.00597569 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | -0.00596346 |
| C11ORF80 | chromosome 11 open reading frame 80 | -0.00595915 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.00594281 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00593565 |
| BRD4 | bromodomain containing 4 | -0.00593399 |
| PRSS3 | protease, serine, 3 | -0.00592489 |
| TUBA4A | tubulin, alpha 4a | -0.00592258 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00591891 |
| ADIRF | adipogenesis regulatory factor | -0.00589086 |
| RBM47 | RNA binding motif protein 47 | -0.00587642 |
| STK17A | serine/threonine kinase 17a | -0.00587356 |
| CCDC92 | coiled-coil domain containing 92 | -0.00585675 |
| ZNF83 | zinc finger protein 83 | -0.00584302 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -0.00583129 |
| METTL7A | methyltransferase like 7A | -0.00582532 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00581782 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00581305 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | -0.00580431 |
| PGLS | 6-phosphogluconolactonase | -0.0058035 |
| ERGIC2 | ERGIC and golgi 2 | -0.00576577 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.00575887 |
| KRT10 | keratin 10, type I | -0.00575385 |
| SIK1 | salt-inducible kinase 1 | -0.00572697 |
| S100A11 | S100 calcium binding protein A11 | -0.00571165 |
| ZNF117 | zinc finger protein 117 | -0.00571102 |
| CAV2 | caveolin 2 | -0.00570977 |
| JUP | junction plakoglobin | -0.00570269 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00568241 |
| CLC | Charcot-Leyden crystal galectin | -0.00567587 |
| BPGM | 2,3-bisphosphoglycerate mutase | -0.00565637 |
| ZYX | zyxin | -0.00565347 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00564918 |
| STC2 | stanniocalcin 2 | -0.00564482 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0056396 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.00562979 |
| COMMD3 | COMM domain containing 3 | -0.00561832 |
| KLK7 | kallikrein-related peptidase 7 | -0.00561536 |
| HOPX | HOP homeobox | -0.00561501 |
| ARG1 | arginase 1 | -0.00561404 |
| BCL2L1 | BCL2-like 1 | -0.00560114 |
| KRT18 | keratin 18, type I | -0.00558632 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00558461 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0055775 |
| TPBG | trophoblast glycoprotein | -0.00557414 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00557048 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00556813 |
| HOXC6 | homeobox C6 | -0.00556453 |
| ZNF611 | zinc finger protein 611 | -0.00556375 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.00555347 |
| HMOX1 | heme oxygenase 1 | -0.00554662 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.00554514 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.00552738 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -0.00552616 |
| SDC1 | syndecan 1 | -0.00550601 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00550066 |
| CLTA | clathrin, light chain A | -0.00550027 |
| WTAP | Wilms tumor 1 associated protein | -0.00549037 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00548153 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -0.00546172 |
| C9ORF16 | chromosome 9 open reading frame 16 | -0.00545995 |
| PAEP | progestagen-associated endometrial protein | -0.00544861 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.0054394 |
| FKBP14 | FK506 binding protein 14, 22 kDa | -0.00543688 |
| ANXA1 | annexin A1 | -0.00543312 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.0054321 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | -0.00541395 |
| ITGA6 | integrin, alpha 6 | -0.00540681 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | -0.00539769 |
| KLF13 | Kruppel-like factor 13 | -0.00539229 |
| HOXB7 | homeobox B7 | -0.00539031 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | -0.00538927 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00538817 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | -0.00537734 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00534755 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00534517 |
| GLTP | glycolipid transfer protein | -0.00534122 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | -0.00532783 |
| SNAP23 | synaptosomal-associated protein, 23kDa | -0.00531936 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.00531812 |
| SYNGR2 | synaptogyrin 2 | -0.00531485 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.00530148 |
| BAD | BCL2-associated agonist of cell death | -0.00529956 |
