HLA-DOA Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description major histocompatibility complex, class II, DO alpha|HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3111)
External Link http://www.ncbi.nlm.nih.gov/gene/3111
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Genes

5 interacting proteins for HLA-DOA from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DOB major histocompatibility complex, class II, DO beta
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
UBC ubiquitin C