| Dataset | Pathway Commons Protein-Protein Interactions |
| Category | physical interactions |
| Type | interacting protein |
| Description | major histocompatibility complex, class II, DO alpha|HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3111) |
| External Link | http://www.ncbi.nlm.nih.gov/gene/3111 |
| Similar Terms | |
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5 interacting proteins for HLA-DOA from the Pathway Commons Protein-Protein Interactions dataset.
