|Dataset||Pathway Commons Protein-Protein Interactions|
|Description||major histocompatibility complex, class II, DO alpha|HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3111)|
|Downloads & Tools|
5 interacting proteins for HLA-DOA from the Pathway Commons Protein-Protein Interactions dataset.