| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | major histocompatibility complex, class II, DP alpha 1|HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3113) |
| External Link | https://ncbi.nlm.nih.gov/gene/3113 |
| Similar Terms | |
| Downloads & Tools |
464 genes differentially expressed following the HLA-DPA1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | 0.0216591 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0173181 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0146362 |
| MAP7 | microtubule-associated protein 7 | 0.0145829 |
| LCN2 | lipocalin 2 | 0.0134075 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.0133984 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.0117875 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0117356 |
| CDC20 | cell division cycle 20 | 0.011239 |
| ECM1 | extracellular matrix protein 1 | 0.0107825 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0106208 |
| H1-0 | H1.0 linker histone | 0.0105859 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.01052 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.0102558 |
| BLNK | B-cell linker | 0.0101418 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.0101333 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.0100628 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00999462 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 0.00997775 |
| PEG10 | paternally expressed 10 | 0.00994978 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00990423 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00990049 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00982423 |
| ACAA2 | acetyl-CoA acyltransferase 2 | 0.00965018 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00964749 |
| MT1X | metallothionein 1X | 0.00959252 |
| MAOA | monoamine oxidase A | 0.00949072 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00944682 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00938362 |
| CA12 | carbonic anhydrase XII | 0.0092817 |
| RRBP1 | ribosome binding protein 1 | 0.00924853 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00922259 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00921671 |
| MT1E | metallothionein 1E | 0.00919917 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | 0.00902716 |
| MGLL | monoglyceride lipase | 0.00896488 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00894847 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00891111 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00888925 |
| CD9 | CD9 molecule | 0.0088725 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00883479 |
| XIC | X chromosome inactivation center | 0.00880087 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00878317 |
| SGCE | sarcoglycan, epsilon | 0.00875013 |
| ANK2 | ankyrin 2, neuronal | 0.00872661 |
| GNAS | GNAS complex locus | 0.00871523 |
| IPO13 | importin 13 | 0.00866619 |
| EMX2 | empty spiracles homeobox 2 | 0.00865177 |
| HOXB2 | homeobox B2 | 0.00864975 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00859036 |
| SCG5 | secretogranin V | 0.00853818 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00852755 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00849062 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00848365 |
| RETREG1 | reticulophagy regulator 1 | 0.00832489 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00831385 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00829916 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00828987 |
| QPRT | quinolinate phosphoribosyltransferase | 0.00825784 |
| MEIS1 | Meis homeobox 1 | 0.00820285 |
| CHGB | chromogranin B | 0.00820019 |
| MT1G | metallothionein 1G | 0.00819623 |
| TUBB3 | tubulin, beta 3 class III | 0.00811615 |
| TCF4 | transcription factor 4 | 0.00807516 |
| CTSZ | cathepsin Z | 0.00800502 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.0079909 |
| PCOLCE | procollagen C-endopeptidase enhancer | 0.00784946 |
| OLFM4 | olfactomedin 4 | 0.00784143 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00781311 |
| PDGFD | platelet derived growth factor D | 0.00777271 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00774972 |
| RND3 | Rho family GTPase 3 | 0.00773388 |
| CLU | clusterin | 0.00772176 |
| TSPYL5 | TSPY-like 5 | 0.00772092 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.00769284 |
| CTSC | cathepsin C | 0.00768235 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00767386 |
| IL1R1 | interleukin 1 receptor, type I | 0.00766692 |
| GPX3 | glutathione peroxidase 3 | 0.00765293 |
| AMOTL2 | angiomotin like 2 | 0.00763474 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.00761319 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0076044 |
| BMP4 | bone morphogenetic protein 4 | 0.00757535 |
| TCTA | T-cell leukemia translocation altered | 0.00756631 |
| FMO1 | flavin containing monooxygenase 1 | 0.00751806 |
| AGTR1 | angiotensin II receptor, type 1 | 0.00748535 |
| LYPD3 | LY6/PLAUR domain containing 3 | 0.00746475 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00745674 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00744011 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0073833 |
| KRT7 | keratin 7, type II | 0.00738119 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00736745 |
| PCP4 | Purkinje cell protein 4 | 0.00736668 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00734143 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00731048 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00730834 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00729626 |
| PLIN2 | perilipin 2 | 0.00725995 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00724322 |
| ZNF91 | zinc finger protein 91 | 0.00717584 |
| FBN2 | fibrillin 2 | 0.00716891 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00712998 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00710389 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.00709676 |
| TWIST1 | twist family bHLH transcription factor 1 | 0.00709393 |
| ANGPT1 | angiopoietin 1 | 0.00706156 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | 0.0070548 |
| COL9A2 | collagen, type IX, alpha 2 | 0.00704725 |
| MMP7 | matrix metallopeptidase 7 | 0.00704217 |
| ALB | albumin | 0.00701229 |
| TMSB15A | thymosin beta 15a | 0.00699821 |
| S100A14 | S100 calcium binding protein A14 | 0.00699617 |
| NEBL | nebulette | 0.00697303 |
| PCDH9 | protocadherin 9 | 0.00697158 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00694123 |
| ABAT | 4-aminobutyrate aminotransferase | 0.00693103 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.00689898 |
| MT1F | metallothionein 1F | 0.00687264 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 0.00684956 |
| MT1H | metallothionein 1H | 0.00684836 |
| TP53I3 | tumor protein p53 inducible protein 3 | 0.00683912 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.00683403 |
| DUSP5 | dual specificity phosphatase 5 | 0.00683389 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00683384 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00682607 |
| BMP2 | bone morphogenetic protein 2 | 0.00681639 |
| PDZK1 | PDZ domain containing 1 | 0.00681154 |
| FHL1 | four and a half LIM domains 1 | 0.0068102 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00680266 |
| SQSTM1 | sequestosome 1 | 0.00678939 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 | 0.00678004 |
| ADIRF | adipogenesis regulatory factor | 0.00674573 |
| DPP4 | dipeptidyl-peptidase 4 | 0.00670971 |
| PPL | periplakin | 0.00670362 |
| CCL21 | chemokine (C-C motif) ligand 21 | 0.006696 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00668945 |
| CCNG2 | cyclin G2 | 0.00668789 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00668015 |
| FOXD1 | forkhead box D1 | 0.00667032 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.00665021 |
| LRP2 | low density lipoprotein receptor-related protein 2 | 0.0066483 |
| PCBP4 | poly(rC) binding protein 4 | 0.00664426 |
| PBLD | phenazine biosynthesis-like protein domain containing | 0.00664189 |
| PFKP | phosphofructokinase, platelet | 0.00663699 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00662721 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00662624 |
| DUSP4 | dual specificity phosphatase 4 | 0.00659469 |
| RTN3 | reticulon 3 | 0.00657371 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00656283 |
| METTL7A | methyltransferase like 7A | 0.00655194 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.0065211 |
| PDGFC | platelet derived growth factor C | 0.00651334 |
| SC5D | sterol-C5-desaturase | 0.00650758 |
| CLEC3B | C-type lectin domain family 3, member B | 0.00649493 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | 0.00647381 |
| ZIC1 | Zic family member 1 | 0.00645736 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00645659 |
| GCH1 | GTP cyclohydrolase 1 | 0.00644702 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00643533 |
| SMAD7 | SMAD family member 7 | 0.00643283 |
| MFAP5 | microfibrillar associated protein 5 | 0.0064274 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00641758 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | 0.00641361 |
| MGP | matrix Gla protein | 0.00639184 |
| NOTCH1 | notch 1 | 0.00638451 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00637966 |
| ADCY9 | adenylate cyclase 9 | 0.0063701 |
| TPBG | trophoblast glycoprotein | 0.00636168 |
| BRD4 | bromodomain containing 4 | 0.00635648 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 | 0.00632248 |
| TENM3 | teneurin transmembrane protein 3 | 0.00630367 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.00628346 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00625745 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00625554 |
| TMEM131L | transmembrane 131 like | 0.00625229 |
| OGDHL | oxoglutarate dehydrogenase-like | 0.00624725 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00624575 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.00623651 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00622857 |
| TEX10 | testis expressed 10 | 0.006185 |
| OSBPL1A | oxysterol binding protein-like 1A | 0.00616069 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00614919 |
| GSTP1 | glutathione S-transferase pi 1 | 0.0061472 |
| COLEC12 | collectin sub-family member 12 | 0.00613644 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00613532 |
| RRAGD | Ras-related GTP binding D | 0.00612202 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.00612129 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | 0.00611835 |
| HIRA | histone cell cycle regulator | 0.00610553 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.00609266 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.00608292 |
| SASH1 | SAM and SH3 domain containing 1 | 0.00607074 |
| TJP2 | tight junction protein 2 | 0.00606328 |
| WDR7 | WD repeat domain 7 | 0.00603485 |
| KLF6 | Kruppel-like factor 6 | 0.00601395 |
| IRS1 | insulin receptor substrate 1 | 0.00601324 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.00600219 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00600177 |
| LIPG | lipase, endothelial | 0.0059997 |
| CPE | carboxypeptidase E | 0.005998 |
| VLDLR | very low density lipoprotein receptor | 0.00599197 |
| CES1 | carboxylesterase 1 | 0.00599172 |
| DTX4 | deltex 4, E3 ubiquitin ligase | 0.00598478 |
| ALDOB | aldolase B, fructose-bisphosphate | 0.00597161 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 | 0.0059601 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.00595947 |
| PHGDH | phosphoglycerate dehydrogenase | 0.0059578 |
| TUBB4B | tubulin, beta 4B class IVb | 0.00595769 |
| PLK2 | polo-like kinase 2 | 0.00595527 |
| LAMB1 | laminin, beta 1 | 0.00594574 |
| NEFM | neurofilament, medium polypeptide | 0.00594448 |
| RTN2 | reticulon 2 | 0.00594022 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.00593874 |
| EPHA2 | EPH receptor A2 | 0.00592101 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0059133 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | 0.00590479 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.00590083 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.0058975 |
| NDRG1 | N-myc downstream regulated 1 | 0.00588785 |
| CUX1 | cut-like homeobox 1 | 0.00588144 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.00587235 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00584905 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00584553 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00583761 |
| ASPA | aspartoacylase | 0.00583545 |
| IGSF3 | immunoglobulin superfamily, member 3 | 0.0058285 |
| PRKD2 | protein kinase D2 | 0.00582294 |
| VPS51 | vacuolar protein sorting 51 homolog (S. cerevisiae) | 0.00581555 |
| TLE4 | transducin-like enhancer of split 4 | 0.00581391 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.00579922 |
| SPRR1A | small proline-rich protein 1A | 0.00579622 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | 0.00577625 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.00576909 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00576312 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0057621 |
| MATN2 | matrilin 2 | 0.00575021 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MMP12 | matrix metallopeptidase 12 | -0.0139395 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0113318 |
| MYBPC1 | myosin binding protein C, slow type | -0.0112457 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.011036 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.0109109 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0107447 |
| LTF | lactotransferrin | -0.0106378 |
| S100A8 | S100 calcium binding protein A8 | -0.0102987 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.0102417 |
| COPS7A | COP9 signalosome subunit 7A | -0.0102318 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0101964 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0100985 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00987961 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00973095 |
| CYBB | cytochrome b-245, beta polypeptide | -0.00970659 |
| METRN | meteorin, glial cell differentiation regulator | -0.00956403 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00920373 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00916847 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00907832 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00903919 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00898744 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00897977 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00893644 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00875199 |
| FOLR1 | folate receptor 1 (adult) | -0.00875163 |
| CHN1 | chimerin 1 | -0.00874263 |
| FBXO11 | F-box protein 11 | -0.00873718 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00871641 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00868936 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00853344 |
| BCL2A1 | BCL2-related protein A1 | -0.00850737 |
| STXBP2 | syntaxin binding protein 2 | -0.00849885 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00838265 |
| NKG7 | natural killer cell granule protein 7 | -0.00837993 |
| ITGA6 | integrin, alpha 6 | -0.00830043 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00829994 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.0082877 |
| DAXX | death-domain associated protein | -0.00822388 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00819299 |
| GPM6B | glycoprotein M6B | -0.00814841 |
| LOX | lysyl oxidase | -0.00803392 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | -0.0080165 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00796297 |
| CLEC5A | C-type lectin domain family 5, member A | -0.00790713 |
| TSPAN8 | tetraspanin 8 | -0.00790601 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | -0.00787834 |
| CD69 | CD69 molecule | -0.00787446 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | -0.00786787 |
| FPR1 | formyl peptide receptor 1 | -0.00786254 |
| GPR65 | G protein-coupled receptor 65 | -0.00783709 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | -0.00780272 |
| THBS1 | thrombospondin 1 | -0.00779288 |
| JAG1 | jagged 1 | -0.00777917 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00776308 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.0077382 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00772369 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00770909 |
| GLUL | glutamate-ammonia ligase | -0.00769422 |
| GPX2 | glutathione peroxidase 2 | -0.00763551 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00762609 |
| RGCC | regulator of cell cycle | -0.00761702 |
| ANXA1 | annexin A1 | -0.00756242 |
| MUC4 | mucin 4, cell surface associated | -0.0075136 |
| C3AR1 | complement component 3a receptor 1 | -0.00746725 |
| GIMAP4 | GTPase, IMAP family member 4 | -0.00745159 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | -0.00739815 |
| ZNF652 | zinc finger protein 652 | -0.00739699 |
| VPS35 | vacuolar protein sorting 35 homolog (S. cerevisiae) | -0.00737359 |
| DMAC2L | distal membrane arm assembly component 2 like | -0.00726227 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.0071865 |
| MMP11 | matrix metallopeptidase 11 | -0.00718254 |
| FABP7 | fatty acid binding protein 7, brain | -0.00717963 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.00715051 |
| AQP9 | aquaporin 9 | -0.00712939 |
| BPI | bactericidal/permeability-increasing protein | -0.00712755 |
| HEPH | hephaestin | -0.00709941 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) | -0.0070928 |
| LY96 | lymphocyte antigen 96 | -0.00707293 |
| RALB | v-ral simian leukemia viral oncogene homolog B | -0.00705623 |
| GPC3 | glypican 3 | -0.00705001 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00700845 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.0070009 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.00698844 |
| TRIB2 | tribbles pseudokinase 2 | -0.00698471 |
| COG7 | component of oligomeric golgi complex 7 | -0.00697245 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00694694 |
| DIO2 | deiodinase, iodothyronine, type II | -0.00693678 |
| TESC | tescalcin | -0.00692131 |
| SKP1 | S-phase kinase-associated protein 1 | -0.00691634 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | -0.00691402 |
| GAS1 | growth arrest-specific 1 | -0.00691358 |
| NLRP2 | NLR family, pyrin domain containing 2 | -0.00691251 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00688675 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00686882 |
| PLP1 | proteolipid protein 1 | -0.00686422 |
| ADORA2B | adenosine A2b receptor | -0.00684089 |
| S100A2 | S100 calcium binding protein A2 | -0.00683326 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00680688 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00679301 |
| NXT2 | nuclear transport factor 2-like export factor 2 | -0.00677337 |
| PEG3 | paternally expressed 3 | -0.00676865 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00676597 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.00675799 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00675469 |
| ATP5F1C | ATP synthase F1 subunit gamma | -0.00675263 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | -0.00674896 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00674539 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -0.00672988 |
| SERINC5 | serine incorporator 5 | -0.0067272 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00671313 |
| RNASET2 | ribonuclease T2 | -0.00669703 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00662322 |
| LST1 | leukocyte specific transcript 1 | -0.00661852 |
| CDCA4 | cell division cycle associated 4 | -0.0066053 |
| CD163 | CD163 molecule | -0.00660184 |
| HAT1 | histone acetyltransferase 1 | -0.00660024 |
| IFI44L | interferon-induced protein 44-like | -0.00659271 |
| CD14 | CD14 molecule | -0.00659101 |
| GUCY2C | guanylate cyclase 2C | -0.00656226 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00655066 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.00654279 |
| PFDN4 | prefoldin subunit 4 | -0.00654194 |
| MUC16 | mucin 16, cell surface associated | -0.00652514 |
| S100P | S100 calcium binding protein P | -0.00651713 |
| NPR3 | natriuretic peptide receptor 3 | -0.0065135 |
| NRN1 | neuritin 1 | -0.00650275 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00650238 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00649972 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00649799 |
| MXRA5 | matrix-remodelling associated 5 | -0.00647732 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00646619 |
| MB | myoglobin | -0.00646137 |
| BTG3 | BTG family, member 3 | -0.00645895 |
| CLCA1 | chloride channel accessory 1 | -0.00643068 |
| H3F3B | H3 histone, family 3B (H3.3B) | -0.00640058 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00638294 |
| PTK2 | protein tyrosine kinase 2 | -0.00638258 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00637245 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | -0.00637242 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00633918 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00633781 |
| RPA3 | replication protein A3, 14kDa | -0.00633517 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.00632159 |
| IQCG | IQ motif containing G | -0.0063187 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | -0.00631621 |
| NCF2 | neutrophil cytosolic factor 2 | -0.00629557 |
| GCK | glucokinase (hexokinase 4) | -0.00628373 |
| IPO7 | importin 7 | -0.00628096 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00627343 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00627036 |
| FYB1 | FYN binding protein 1 | -0.00626801 |
| S100A9 | S100 calcium binding protein A9 | -0.00625049 |
| TSPAN6 | tetraspanin 6 | -0.00625 |
| EXOC5 | exocyst complex component 5 | -0.0062494 |
| A2M | alpha-2-macroglobulin | -0.00623609 |
| LBH | limb bud and heart development | -0.00622687 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | -0.00620826 |
| PYCARD | PYD and CARD domain containing | -0.00620794 |
| CYB5R4 | cytochrome b5 reductase 4 | -0.00619937 |
| CD83 | CD83 molecule | -0.00619784 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | -0.00619243 |
| DAZAP2 | DAZ associated protein 2 | -0.00617835 |
| CD48 | CD48 molecule | -0.00616385 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | -0.00615797 |
| IFI44 | interferon-induced protein 44 | -0.00615454 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -0.00615157 |
| S100A12 | S100 calcium binding protein A12 | -0.00614444 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | -0.00612031 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.00609568 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00609219 |
| SMC1A | structural maintenance of chromosomes 1A | -0.00607181 |
| TYROBP | TYRO protein tyrosine kinase binding protein | -0.00606923 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00606502 |
| RXYLT1 | ribitol xylosyltransferase 1 | -0.0060451 |
| PTH2R | parathyroid hormone 2 receptor | -0.00604318 |
| HOPX | HOP homeobox | -0.00604096 |
| ITM2A | integral membrane protein 2A | -0.00604064 |
| HSBP1 | heat shock factor binding protein 1 | -0.00604032 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00601637 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00601573 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00599972 |
| CANX | calnexin | -0.00599623 |
| FZD5 | frizzled class receptor 5 | -0.00599391 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00599297 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00599074 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.00598312 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00597996 |
| WT1 | Wilms tumor 1 | -0.00596951 |
| S100A10 | S100 calcium binding protein A10 | -0.00596603 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00596292 |
| COL21A1 | collagen, type XXI, alpha 1 | -0.00596248 |
| COL1A2 | collagen, type I, alpha 2 | -0.00595757 |
| RHOA | ras homolog family member A | -0.0059481 |
| CST7 | cystatin F (leukocystatin) | -0.00594456 |
| CORO2A | coronin, actin binding protein, 2A | -0.00592569 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.0059014 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | -0.00589775 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00589548 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.00588231 |
| COMMD10 | COMM domain containing 10 | -0.00586938 |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 | -0.00586243 |
| HBB | hemoglobin, beta | -0.00586155 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.00585732 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00584961 |
| ANOS1 | anosmin 1 | -0.00583952 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -0.00582652 |
| S100A7 | S100 calcium binding protein A7 | -0.00582344 |
| ITK | IL2-inducible T-cell kinase | -0.00581872 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00581784 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | -0.00581236 |
| THBD | thrombomodulin | -0.00579764 |
| FCGBP | Fc fragment of IgG binding protein | -0.00579461 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | -0.00579121 |
| PRR5L | proline rich 5 like | -0.00578902 |
| TTN | titin | -0.00578713 |
| PODXL | podocalyxin-like | -0.00578529 |
| SET | SET nuclear proto-oncogene | -0.00577739 |
| GDI2 | GDP dissociation inhibitor 2 | -0.00576656 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0057549 |
| TMC5 | transmembrane channel-like 5 | -0.00575424 |
| CYB561 | cytochrome b561 | -0.00575269 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00575069 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00573781 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) | -0.00573013 |
| KLHL7 | kelch-like family member 7 | -0.0057251 |
| CAPRIN1 | cell cycle associated protein 1 | -0.00572102 |
| ATG5 | autophagy related 5 | -0.00570484 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00570481 |
