| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | major histocompatibility complex, class II, DQ alpha 1|HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3117) |
| External Link | https://ncbi.nlm.nih.gov/gene/3117 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the HLA-DQA1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HOPX | HOP homeobox | 0.0194333 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0159475 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0154773 |
| TFF3 | trefoil factor 3 (intestinal) | 0.0154687 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.0143484 |
| KIF20A | kinesin family member 20A | 0.0135129 |
| DIO2 | deiodinase, iodothyronine, type II | 0.0132513 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.0126941 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0126501 |
| PMP22 | peripheral myelin protein 22 | 0.0124442 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.012195 |
| PRF1 | perforin 1 (pore forming protein) | 0.0121484 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0120469 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.0120466 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0120125 |
| HMG20B | high mobility group 20B | 0.0119617 |
| KRT1 | keratin 1, type II | 0.011732 |
| MAP7 | microtubule-associated protein 7 | 0.0116149 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0115642 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0113812 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 0.0113276 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.0112384 |
| SPON2 | spondin 2, extracellular matrix protein | 0.0110312 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.0109101 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.0108125 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0107566 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0107508 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.0107038 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.010695 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.010684 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.0105284 |
| TCF4 | transcription factor 4 | 0.0105116 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.0104898 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0104567 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.0104558 |
| RHOB | ras homolog family member B | 0.0103731 |
| LYZ | lysozyme | 0.0102707 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0102579 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.0102523 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.0101798 |
| FASN | fatty acid synthase | 0.0101342 |
| SPRR1B | small proline-rich protein 1B | 0.0101092 |
| C1QB | complement component 1, q subcomponent, B chain | 0.0100938 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.0100627 |
| CD320 | CD320 molecule | 0.0100036 |
| ELP1 | elongator acetyltransferase complex subunit 1 | 0.00991415 |
| PGC | progastricsin (pepsinogen C) | 0.00988916 |
| CD209 | CD209 molecule | 0.00984195 |
| KRT2 | keratin 2, type II | 0.00978573 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00975644 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.00974076 |
| NTS | neurotensin | 0.00968334 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 0.00962267 |
| COPS7A | COP9 signalosome subunit 7A | 0.00955507 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.00951091 |
| PLPP3 | phospholipid phosphatase 3 | 0.00951068 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00948843 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00945771 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 | 0.00938147 |
| SOCS1 | suppressor of cytokine signaling 1 | 0.00937074 |
| CST3 | cystatin C | 0.00934515 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0093129 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0092602 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00925529 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | 0.00924946 |
| TMSB15A | thymosin beta 15a | 0.00924616 |
| EFHD2 | EF-hand domain family, member D2 | 0.00922086 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00919392 |
| PRC1 | protein regulator of cytokinesis 1 | 0.00915209 |
| GSAP | gamma-secretase activating protein | 0.00915003 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00913377 |
| DSG1 | desmoglein 1 | 0.00913237 |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | 0.00905988 |
| ABHD17A | abhydrolase domain containing 17A | 0.00894975 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00894639 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0089387 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.00890745 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00889928 |
| SPRR2B | small proline-rich protein 2B | 0.00886277 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00884175 |
| DMPK | dystrophia myotonica-protein kinase | 0.00876722 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00876108 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.00876065 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | 0.00874662 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 | 0.00872922 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.00864489 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | 0.00863105 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.00861648 |
| PMF1 | polyamine-modulated factor 1 | 0.00861322 |
| LMNB2 | lamin B2 | 0.00858243 |
| SFN | stratifin | 0.00857359 |
| CALML5 | calmodulin-like 5 | 0.00856986 |
| GNLY | granulysin | 0.00856473 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.0085631 |
| FOXF1 | forkhead box F1 | 0.00854776 |
| NUCB1 | nucleobindin 1 | 0.00852918 |
| IL2RB | interleukin 2 receptor, beta | 0.00852416 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.00849789 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 0.00847481 |
| SPRR1A | small proline-rich protein 1A | 0.00846034 |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.0084218 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00841111 |
| CNNM3 | cyclin and CBS domain divalent metal cation transport mediator 3 | 0.00840733 |
| HDHD5 | haloacid dehalogenase like hydrolase domain containing 5 | 0.0084025 |
| RHOA | ras homolog family member A | 0.00839102 |
| CDC25B | cell division cycle 25B | 0.00835748 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.00835613 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | 0.00831818 |
| AADAC | arylacetamide deacetylase | 0.00831794 |
| CTBP1 | C-terminal binding protein 1 | 0.00830945 |
| RPA1 | replication protein A1, 70kDa | 0.00830497 |
| APOD | apolipoprotein D | 0.00829109 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.00828906 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00828847 |
| REG3A | regenerating islet-derived 3 alpha | 0.00828833 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00828235 |
| RANBP1 | RAN binding protein 1 | 0.00827346 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.00827111 |
| KRT16 | keratin 16, type I | 0.00822395 |
| APMAP | adipocyte plasma membrane associated protein | 0.00822186 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.00821571 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00819483 |
| LYPD3 | LY6/PLAUR domain containing 3 | 0.00818399 |
| FZD2 | frizzled class receptor 2 | 0.00818044 |
| NKG7 | natural killer cell granule protein 7 | 0.00816014 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.00815568 |
| NPC1 | Niemann-Pick disease, type C1 | 0.00811961 |
| MCM5 | minichromosome maintenance complex component 5 | 0.0081048 |
| DENND4B | DENN/MADD domain containing 4B | 0.00810277 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00809191 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00808408 |
| TRIM28 | tripartite motif containing 28 | 0.00807629 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.00807511 |
| CALML3 | calmodulin-like 3 | 0.00806957 |
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | 0.00806845 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00805837 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00804399 |
| TIMELESS | timeless circadian clock | 0.00802165 |
| GSTA1 | glutathione S-transferase alpha 1 | 0.00799095 |
| ACTC1 | actin, alpha, cardiac muscle 1 | 0.00798152 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0079784 |
| TXLNA | taxilin alpha | 0.00794924 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 0.0079324 |
| TGM3 | transglutaminase 3 | 0.00792268 |
| GSTA4 | glutathione S-transferase alpha 4 | 0.00786986 |
| UBAP2L | ubiquitin associated protein 2-like | 0.00784677 |
| MMP2 | matrix metallopeptidase 2 | 0.00782696 |
| COL4A2 | collagen, type IV, alpha 2 | 0.00779137 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00776872 |
| CHN1 | chimerin 1 | 0.00775887 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.00772277 |
| RAPSN | receptor-associated protein of the synapse | 0.00772265 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.00770884 |
| YBX3 | Y box binding protein 3 | 0.00769798 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.00768928 |
| DGS2 | DiGeorge syndrome/velocardiofacial syndrome complex 2 | 0.00768689 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 0.00768134 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | 0.00765584 |
| BCHE | butyrylcholinesterase | 0.00763455 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.00759629 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 0.00759513 |
| RXRA | retinoid X receptor, alpha | 0.00757866 |
| CCL13 | chemokine (C-C motif) ligand 13 | 0.00754473 |
| XCL1 | chemokine (C motif) ligand 1 | 0.00753294 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 | 0.00752888 |
| ACTB | actin, beta | 0.00751923 |
| REX1BD | required for excision 1-B domain containing | 0.00749676 |
| PNKP | polynucleotide kinase 3'-phosphatase | 0.00748081 |
| MCM3 | minichromosome maintenance complex component 3 | 0.00746625 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.00746479 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00744893 |
| TP63 | tumor protein p63 | 0.00744245 |
| FOXM1 | forkhead box M1 | 0.00743762 |
| HDAC1 | histone deacetylase 1 | 0.00740644 |
| CDSN | corneodesmosin | 0.00740492 |
| ACTL6A | actin-like 6A | 0.00740295 |
| GRAMD4 | GRAM domain containing 4 | 0.00739506 |
| VWF | von Willebrand factor | 0.00738555 |
| MLPH | melanophilin | 0.00736337 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00730555 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00730129 |
| DGCR8 | DGCR8 microprocessor complex subunit | 0.00730122 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00728115 |
| FANCG | Fanconi anemia, complementation group G | 0.00725591 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.00725067 |
| DCLK1 | doublecortin-like kinase 1 | 0.00724451 |
| RPL10 | ribosomal protein L10 | 0.00723122 |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 | 0.00722745 |
| DEFB4A | defensin, beta 4A | 0.00721242 |
| EMID1 | EMI domain containing 1 | 0.00720458 |
| FAM193B | family with sequence similarity 193, member B | 0.00720115 |
| NES | nestin | 0.00716586 |
| SDC3 | syndecan 3 | 0.00712786 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | 0.00712357 |
| RASIP1 | Ras interacting protein 1 | 0.00709483 |
| H2AX | H2A.X variant histone | 0.0070942 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.00706103 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00704254 |
| DAZAP1 | DAZ associated protein 1 | 0.00703769 |
| SDF4 | stromal cell derived factor 4 | 0.00702156 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00700629 |
| SETDB1 | SET domain, bifurcated 1 | 0.00699895 |
| DSC1 | desmocollin 1 | 0.00696466 |
| KIF18B | kinesin family member 18B | 0.00695832 |
| TMEM106C | transmembrane protein 106C | 0.00694659 |
| KRT6A | keratin 6A, type II | 0.0069431 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | 0.0069423 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | 0.00693295 |
| LOR | loricrin | 0.00690005 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00689493 |
| THAP12 | THAP domain containing 12 | 0.00689064 |
| PHB2 | prohibitin 2 | 0.00688151 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.00685618 |
| SETBP1 | SET binding protein 1 | 0.00685444 |
| UBE2M | ubiquitin-conjugating enzyme E2M | 0.0068427 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 0.00683708 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00681885 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00681584 |
| GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa | 0.00681515 |
| CA2 | carbonic anhydrase II | 0.00678846 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 | 0.00678338 |
| MED22 | mediator complex subunit 22 | 0.00677744 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00677445 |
| DNM1 | dynamin 1 | 0.00677139 |
| SDHAP1 | succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 | 0.00674511 |
| PXN | paxillin | 0.00673465 |
| CPQ | carboxypeptidase Q | 0.00672647 |
| CRCT1 | cysteine-rich C-terminal 1 | 0.00672329 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.00672039 |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.00671853 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 | 0.00671737 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 0.00671712 |
| CCNF | cyclin F | 0.006717 |
| MSX1 | msh homeobox 1 | 0.00669822 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00668847 |
| ECT2 | epithelial cell transforming 2 | 0.00667831 |
| RBM6 | RNA binding motif protein 6 | 0.0066172 |
| MTA1 | metastasis associated 1 | 0.00661645 |
| BSG | basigin (Ok blood group) | 0.00660688 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.0066048 |
| CA9 | carbonic anhydrase IX | 0.00659848 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00659796 |
| INTS1 | integrator complex subunit 1 | 0.00659778 |
| GTSE1 | G-2 and S-phase expressed 1 | 0.0065925 |
| IER2 | immediate early response 2 | 0.00659196 |
| NOTCH2 | notch 2 | 0.00658987 |
| PAPOLA | poly(A) polymerase alpha | 0.00658592 |
| NSMCE4A | non-SMC element 4 homolog A (S. cerevisiae) | 0.00658297 |
| DES | desmin | 0.00658279 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT19 | keratin 19, type I | -0.0189415 |
| HTRA1 | HtrA serine peptidase 1 | -0.0186173 |
| ASS1 | argininosuccinate synthase 1 | -0.0184721 |
| THBS2 | thrombospondin 2 | -0.0177907 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0177162 |
| CRYAB | crystallin, alpha B | -0.0170372 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0168681 |
| AOC1 | amine oxidase, copper containing 1 | -0.0167316 |
| MAL | mal, T-cell differentiation protein | -0.0166015 |
| ADD3 | adducin 3 (gamma) | -0.016536 |
| THBS1 | thrombospondin 1 | -0.016215 |
| RBM34 | RNA binding motif protein 34 | -0.0161053 |
| FOLR1 | folate receptor 1 (adult) | -0.0158212 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.0154104 |
| INHBA | inhibin, beta A | -0.0152715 |
| BEX4 | brain expressed, X-linked 4 | -0.0151146 |
| GNAS | GNAS complex locus | -0.0151055 |
| ABAT | 4-aminobutyrate aminotransferase | -0.0146471 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.0144098 |
| ATF3 | activating transcription factor 3 | -0.0143833 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.0141402 |
| HIST1H2AC | histone cluster 1, H2ac | -0.013895 |
| EPCAM | epithelial cell adhesion molecule | -0.0137398 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0137128 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.0136976 |
| SGCE | sarcoglycan, epsilon | -0.013583 |
| VCAN | versican | -0.0135477 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.0134833 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0133076 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.0132698 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0131673 |
| LXN | latexin | -0.0127302 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.0124841 |
| ADIRF | adipogenesis regulatory factor | -0.0124253 |
| LCN2 | lipocalin 2 | -0.0124192 |
| PADI2 | peptidyl arginine deiminase, type II | -0.0123449 |
| CLIC5 | chloride intracellular channel 5 | -0.0121964 |
| MSLN | mesothelin | -0.0121384 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.012097 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0120017 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.0118659 |
| EVI2A | ecotropic viral integration site 2A | -0.0118585 |
| ANXA1 | annexin A1 | -0.0117885 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0117361 |
| CTSD | cathepsin D | -0.0116315 |
| AREG | amphiregulin | -0.0115409 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.0114988 |
| FN1 | fibronectin 1 | -0.0114901 |
| RGS10 | regulator of G-protein signaling 10 | -0.0114731 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.0114679 |
| C6ORF48 | chromosome 6 open reading frame 48 | -0.0114091 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.0113554 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0113425 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0111013 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.0110118 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0108896 |
| RPS27L | ribosomal protein S27-like | -0.0108604 |
| HIST1H2BD | histone cluster 1, H2bd | -0.0108519 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.0108273 |
| CFI | complement factor I | -0.010805 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.0107863 |
| G0S2 | G0/G1 switch 2 | -0.0107593 |
| NPY1R | neuropeptide Y receptor Y1 | -0.0107542 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | -0.0106918 |
| PLLP | plasmolipin | -0.0106865 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.0106771 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0106671 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0105426 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0104839 |
| CAST | calpastatin | -0.0104043 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.0103372 |
| GPR137B | G protein-coupled receptor 137B | -0.0103322 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | -0.0102449 |
| DEFB1 | defensin, beta 1 | -0.0101823 |
| CFB | complement factor B | -0.0101766 |
| LAMB1 | laminin, beta 1 | -0.0100981 |
| MXRA5 | matrix-remodelling associated 5 | -0.0100893 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | -0.010081 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0100632 |
| ITM2C | integral membrane protein 2C | -0.0100515 |
| CALB1 | calbindin 1, 28kDa | -0.00997892 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00996055 |
| MUC16 | mucin 16, cell surface associated | -0.00993268 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00992657 |
| COL10A1 | collagen, type X, alpha 1 | -0.00987792 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00987535 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.00983382 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00977505 |
| PEG3 | paternally expressed 3 | -0.00977387 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -0.00973373 |
| SH3BGR | SH3 domain binding glutamate-rich protein | -0.00969903 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.0096896 |
| METRN | meteorin, glial cell differentiation regulator | -0.00958741 |
| COG7 | component of oligomeric golgi complex 7 | -0.00957326 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00954205 |
| RCAN1 | regulator of calcineurin 1 | -0.00951802 |
| COMP | cartilage oligomeric matrix protein | -0.00941594 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.00937285 |
| EIF5 | eukaryotic translation initiation factor 5 | -0.00936039 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00934907 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.00934887 |
| GOLT1B | golgi transport 1B | -0.00931804 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00930436 |
| DCN | decorin | -0.00928185 |
| GGPS1 | geranylgeranyl diphosphate synthase 1 | -0.0092685 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.00926623 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0092658 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.00921362 |
| MRPS33 | mitochondrial ribosomal protein S33 | -0.00920898 |
| GPX3 | glutathione peroxidase 3 | -0.00920046 |
| INAVA | innate immunity activator | -0.00918693 |
| MGP | matrix Gla protein | -0.00917681 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 | -0.00914831 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00912314 |
| RRAGD | Ras-related GTP binding D | -0.00911336 |
| LEFTY1 | left-right determination factor 1 | -0.00908345 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00907685 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | -0.00907262 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0090464 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.00900698 |
| CLDN8 | claudin 8 | -0.00900641 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00898274 |
| L1CAM | L1 cell adhesion molecule | -0.00895907 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00893123 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | -0.00887921 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00886946 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00884479 |
| BCL2A1 | BCL2-related protein A1 | -0.0087779 |
| PITX3 | paired-like homeodomain 3 | -0.00877708 |
| PROM1 | prominin 1 | -0.00877555 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.00876501 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.00875037 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | -0.00873356 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00871084 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | -0.0087089 |
| SCG5 | secretogranin V | -0.00868532 |
| RPL26L1 | ribosomal protein L26-like 1 | -0.00868063 |
| NMRK1 | nicotinamide riboside kinase 1 | -0.00864458 |
| AZIN1 | antizyme inhibitor 1 | -0.00862805 |
| UMOD | uromodulin | -0.00860956 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00859112 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.00857841 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.00855985 |
| FGF1 | fibroblast growth factor 1 (acidic) | -0.00855751 |
| BGN | biglycan | -0.00855213 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.00855118 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00854714 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa | -0.00853924 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.00848539 |
| ANXA6 | annexin A6 | -0.00848362 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00845859 |
| ANXA3 | annexin A3 | -0.00845559 |
| CLDN3 | claudin 3 | -0.00845075 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | -0.00843237 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00842693 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.00841156 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00839651 |
| PPA1 | pyrophosphatase (inorganic) 1 | -0.00832641 |
| FDX1 | ferredoxin 1 | -0.00830529 |
| SNAI2 | snail family zinc finger 2 | -0.00830444 |
| LRRC15 | leucine rich repeat containing 15 | -0.00829762 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00829478 |
| ASPN | asporin | -0.00829241 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 | -0.00827327 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | -0.00827047 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | -0.00826414 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00826191 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00825233 |
| OLFML3 | olfactomedin-like 3 | -0.00824995 |
| SP100 | SP100 nuclear antigen | -0.0082035 |
| LPXN | leupaxin | -0.00819875 |
| GPX7 | glutathione peroxidase 7 | -0.00819398 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.00818284 |
| GPM6B | glycoprotein M6B | -0.00816956 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00816227 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00814992 |
| C5AR1 | complement component 5a receptor 1 | -0.00814216 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.0081233 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | -0.00811838 |
| NME5 | NME/NM23 family member 5 | -0.00810346 |
| SLC16A4 | solute carrier family 16, member 4 | -0.0081005 |
| IFRD2 | interferon-related developmental regulator 2 | -0.00808599 |
| HSPA8 | heat shock 70kDa protein 8 | -0.00808004 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00807914 |
| MMD | monocyte to macrophage differentiation-associated | -0.00806835 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | -0.00805293 |
| NGRN | neugrin, neurite outgrowth associated | -0.00804594 |
| PNMA8A | PNMA family member 8A | -0.0080327 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | -0.00800624 |
| PDE9A | phosphodiesterase 9A | -0.0080053 |
| ERP44 | endoplasmic reticulum protein 44 | -0.00798195 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | -0.00796896 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | -0.00796586 |
| AKIRIN1 | akirin 1 | -0.00795819 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.00794381 |
| MLF1 | myeloid leukemia factor 1 | -0.00792643 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.00791353 |
| C1ORF54 | chromosome 1 open reading frame 54 | -0.00790316 |
| ICAM2 | intercellular adhesion molecule 2 | -0.00790182 |
| RNF7 | ring finger protein 7 | -0.00787803 |
| ZFAND1 | zinc finger, AN1-type domain 1 | -0.00786785 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0078629 |
| STK10 | serine/threonine kinase 10 | -0.00786274 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.00785991 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00785893 |
| UBFD1 | ubiquitin family domain containing 1 | -0.00785514 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00785282 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.00783869 |
| PTK2 | protein tyrosine kinase 2 | -0.00782853 |
| CCN2 | cellular communication network factor 2 | -0.00782184 |
| TADA2A | transcriptional adaptor 2A | -0.00781781 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.00781735 |
| SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporter), member 1 | -0.00781198 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00779866 |
| SEC11A | SEC11 homolog A (S. cerevisiae) | -0.00777918 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00777135 |
| RTCA | RNA 3'-terminal phosphate cyclase | -0.00776691 |
| CLDN10 | claudin 10 | -0.00776256 |
| NEBL | nebulette | -0.00774794 |
| TP53I3 | tumor protein p53 inducible protein 3 | -0.00771873 |
| S100A10 | S100 calcium binding protein A10 | -0.00770976 |
| RGS4 | regulator of G-protein signaling 4 | -0.00770898 |
| MAP9 | microtubule-associated protein 9 | -0.00770856 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00770211 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00769754 |
| NFU1 | NFU1 iron-sulfur cluster scaffold | -0.00769608 |
| CCNG1 | cyclin G1 | -0.00769393 |
| LYPD1 | LY6/PLAUR domain containing 1 | -0.00769337 |
| C3 | complement component 3 | -0.0076908 |
| IFI44 | interferon-induced protein 44 | -0.00764864 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein | -0.00764035 |
| NANS | N-acetylneuraminic acid synthase | -0.00763726 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0076343 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00761543 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | -0.00760895 |
| DOK5 | docking protein 5 | -0.00760572 |
| DLD | dihydrolipoamide dehydrogenase | -0.00760358 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00759996 |
| KRCC1 | lysine-rich coiled-coil 1 | -0.00759636 |
| MRPL18 | mitochondrial ribosomal protein L18 | -0.00759488 |
| TSPAN1 | tetraspanin 1 | -0.00758493 |
| CDV3 | CDV3 homolog (mouse) | -0.00758226 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.00755729 |
| PODXL | podocalyxin-like | -0.00755495 |
| OPTN | optineurin | -0.00754739 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -0.00754127 |
| IFI44L | interferon-induced protein 44-like | -0.00753772 |
| SC5D | sterol-C5-desaturase | -0.00751706 |
| EIF4E2 | eukaryotic translation initiation factor 4E family member 2 | -0.00751639 |
| OSTF1 | osteoclast stimulating factor 1 | -0.00751302 |
