| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | major histocompatibility complex, class II, DQ alpha 2|This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. [provided by RefSeq, Jun 2010] (NCBI Entrez Gene Database, 3118) |
| External Link | https://ncbi.nlm.nih.gov/gene/3118 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the HLA-DQA2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI27 | interferon, alpha-inducible protein 27 | 0.0161425 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.0159298 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.013399 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0122636 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.0118378 |
| HSPB8 | heat shock 22kDa protein 8 | 0.0117364 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.0117048 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0114607 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0114347 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.0113335 |
| S100P | S100 calcium binding protein P | 0.0112723 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0112136 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.0109781 |
| RNASET2 | ribonuclease T2 | 0.0108024 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.0107366 |
| EDN3 | endothelin 3 | 0.0106702 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.0106385 |
| MECOM | MDS1 and EVI1 complex locus | 0.0100509 |
| ITGA6 | integrin, alpha 6 | 0.00989901 |
| LXN | latexin | 0.00972017 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00967209 |
| C3 | complement component 3 | 0.00956881 |
| TFRC | transferrin receptor | 0.00950865 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00950485 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | 0.0093716 |
| CSTA | cystatin A (stefin A) | 0.00925728 |
| PEG3 | paternally expressed 3 | 0.00922733 |
| KLF6 | Kruppel-like factor 6 | 0.00922249 |
| TRIM22 | tripartite motif containing 22 | 0.0091757 |
| IFNGR1 | interferon gamma receptor 1 | 0.0090728 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0090235 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00900333 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00899724 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00897674 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00894845 |
| ANXA1 | annexin A1 | 0.00886658 |
| THBD | thrombomodulin | 0.00876652 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.0087491 |
| LYZ | lysozyme | 0.00873427 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00862642 |
| PLN | phospholamban | 0.00859102 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.00856495 |
| A2M | alpha-2-macroglobulin | 0.00852826 |
| FGF13 | fibroblast growth factor 13 | 0.00851304 |
| TXN | thioredoxin | 0.0084678 |
| RUNX3 | runt-related transcription factor 3 | 0.00846183 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00844756 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00835798 |
| GOLGA8A | golgin A8 family, member A | 0.00835584 |
| CA2 | carbonic anhydrase II | 0.00834138 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.0083281 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00831712 |
| RGS5 | regulator of G-protein signaling 5 | 0.00830246 |
| BTG2 | BTG family, member 2 | 0.00826523 |
| TSPAN8 | tetraspanin 8 | 0.00825694 |
| ESR1 | estrogen receptor 1 | 0.00824228 |
| PNN | pinin, desmosome associated protein | 0.00821962 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00815303 |
| MYO1B | myosin IB | 0.00814435 |
| ACKR3 | atypical chemokine receptor 3 | 0.00811622 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00810416 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00803042 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00801952 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00797327 |
| TBX3 | T-box 3 | 0.007964 |
| ZNF721 | zinc finger protein 721 | 0.00792708 |
| COG7 | component of oligomeric golgi complex 7 | 0.00791473 |
| RGCC | regulator of cell cycle | 0.00788024 |
| PFDN4 | prefoldin subunit 4 | 0.00786504 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.007861 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0077772 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00773699 |
| EMP1 | epithelial membrane protein 1 | 0.00769822 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00767031 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) | 0.00766125 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00762981 |
| ZNF160 | zinc finger protein 160 | 0.00761826 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | 0.00752773 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00745019 |
| L1CAM | L1 cell adhesion molecule | 0.0073897 |
| CAV2 | caveolin 2 | 0.00737292 |
| SPRR3 | small proline-rich protein 3 | 0.00735679 |
| S100A10 | S100 calcium binding protein A10 | 0.00735316 |
| DES | desmin | 0.00734853 |
| SLC38A2 | solute carrier family 38, member 2 | 0.00733937 |
| MX1 | MX dynamin-like GTPase 1 | 0.00733241 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 0.00731038 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00729545 |
| MAB21L2 | mab-21-like 2 (C. elegans) | 0.00727819 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00727562 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00726048 |
| MPZL2 | myelin protein zero-like 2 | 0.00725444 |
| TFF1 | trefoil factor 1 | 0.00724106 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00722161 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00721851 |
| HSPE1 | heat shock 10kDa protein 1 | 0.00721515 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00715157 |
| CLCA4 | chloride channel accessory 4 | 0.00713884 |
| BMP7 | bone morphogenetic protein 7 | 0.00713138 |
| PTCH1 | patched 1 | 0.00710768 |
| FOXF1 | forkhead box F1 | 0.00709787 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00707361 |
| MX2 | MX dynamin-like GTPase 2 | 0.00706004 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | 0.00705964 |
| MATN2 | matrilin 2 | 0.00705826 |
| PRNP | prion protein | 0.00705611 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00702257 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 0.00702016 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00699094 |
| CHGB | chromogranin B | 0.00698229 |
| HBB | hemoglobin, beta | 0.0069739 |
| RSRP1 | arginine/serine-rich protein 1 | 0.00696248 |
| RUFY2 | RUN and FYVE domain containing 2 | 0.00696247 |
| ABLIM1 | actin binding LIM protein 1 | 0.00694332 |
| PYCARD | PYD and CARD domain containing | 0.00693308 |
| CCNG1 | cyclin G1 | 0.00692996 |
| DUSP5 | dual specificity phosphatase 5 | 0.00692597 |
| CD93 | CD93 molecule | 0.00687512 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.00686516 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.00685751 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00685537 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.00680956 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00680412 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00679382 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00679142 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00679056 |
| GPR87 | G protein-coupled receptor 87 | 0.00678468 |
| FZD6 | frizzled class receptor 6 | 0.00677112 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00675412 |
| NCK1 | NCK adaptor protein 1 | 0.00671723 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00671567 |
| CHN1 | chimerin 1 | 0.00670742 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.00670291 |
| FZD10 | frizzled class receptor 10 | 0.00669353 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00667841 |
| NCAM1 | neural cell adhesion molecule 1 | 0.00665265 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00664798 |
| MCL1 | myeloid cell leukemia 1 | 0.00663404 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.0066245 |
| BMP4 | bone morphogenetic protein 4 | 0.00661133 |
| EGR3 | early growth response 3 | 0.00660853 |
| TGM2 | transglutaminase 2 | 0.00659998 |
| ATF3 | activating transcription factor 3 | 0.00659579 |
| GNAS | GNAS complex locus | 0.00659252 |
| RBM5 | RNA binding motif protein 5 | 0.00659106 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00658903 |
| MSX1 | msh homeobox 1 | 0.00658504 |
| RREB1 | ras responsive element binding protein 1 | 0.00658309 |
| ITM2C | integral membrane protein 2C | 0.00655273 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.00654299 |
| DPP8 | dipeptidyl-peptidase 8 | 0.00652247 |
| IL1RN | interleukin 1 receptor antagonist | 0.00651726 |
| IFI44L | interferon-induced protein 44-like | 0.00650809 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00649783 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.006454 |
| SERINC1 | serine incorporator 1 | 0.00644419 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.00643716 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 0.00643187 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00641851 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0064129 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.00640908 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00637691 |
| MOB4 | MOB family member 4, phocein | 0.0063654 |
| MMP7 | matrix metallopeptidase 7 | 0.006356 |
| OPHN1 | oligophrenin 1 | 0.00634375 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00632981 |
| FCGBP | Fc fragment of IgG binding protein | 0.00632966 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00631138 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00630278 |
| CNTN1 | contactin 1 | 0.00629106 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00628365 |
| IL33 | interleukin 33 | 0.00628365 |
| RPS27L | ribosomal protein S27-like | 0.00627507 |
| TSPAN1 | tetraspanin 1 | 0.00626455 |
| TAC1 | tachykinin, precursor 1 | 0.00624866 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00621791 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.00621394 |
| CTSE | cathepsin E | 0.00621081 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00620635 |
| HLA-B | major histocompatibility complex, class I, B | 0.0061846 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00618204 |
| DCHS1 | dachsous cadherin-related 1 | 0.00616493 |
| TMEM255A | transmembrane protein 255A | 0.0061534 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00614228 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00612626 |
| GPX2 | glutathione peroxidase 2 | 0.00611757 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00609825 |
| PERP | PERP, TP53 apoptosis effector | 0.0060906 |
| SYNM | synemin, intermediate filament protein | 0.00608082 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00603436 |
| MUC4 | mucin 4, cell surface associated | 0.00602052 |
| CHRDL1 | chordin-like 1 | 0.00600099 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.00599676 |
| TESC | tescalcin | 0.00597607 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00595625 |
| FRZB | frizzled-related protein | 0.00595389 |
| FILIP1L | filamin A interacting protein 1-like | 0.00594781 |
| GPM6B | glycoprotein M6B | 0.00593288 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00592889 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.00592478 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00590942 |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 | 0.0059084 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00590431 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.00590392 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00590365 |
| CTSC | cathepsin C | 0.00588881 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00588709 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | 0.00588119 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00586893 |
| MIR22HG | MIR22 host gene | 0.00585701 |
| RELN | reelin | 0.00585288 |
| EMCN | endomucin | 0.00584362 |
| KRT13 | keratin 13, type I | 0.00582387 |
| NAIP | NLR family, apoptosis inhibitory protein | 0.00582028 |
| FN1 | fibronectin 1 | 0.00580415 |
| ZNF611 | zinc finger protein 611 | 0.00580333 |
| MITF | microphthalmia-associated transcription factor | 0.00580036 |
| ASS1 | argininosuccinate synthase 1 | 0.00579396 |
| AHNAK | AHNAK nucleoprotein | 0.00578939 |
| HSPA4 | heat shock 70kDa protein 4 | 0.00578762 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) | 0.00578456 |
| BTG3 | BTG family, member 3 | 0.00578251 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00576793 |
| CD46 | CD46 molecule, complement regulatory protein | 0.00575982 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00575722 |
| ARL14 | ADP-ribosylation factor-like 14 | 0.0057469 |
| DSG3 | desmoglein 3 | 0.0057332 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00572384 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.00571667 |
| PLCB4 | phospholipase C, beta 4 | 0.005714 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00571341 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.00569579 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00569466 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | 0.00569158 |
| SNX13 | sorting nexin 13 | 0.00568144 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.0056767 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00567255 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00565463 |
| CTSH | cathepsin H | 0.00565431 |
| CST1 | cystatin SN | 0.00564304 |
| XK | X-linked Kx blood group | 0.00563642 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00561241 |
| LAMA3 | laminin, alpha 3 | 0.00560971 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00560931 |
| PRKCB | protein kinase C, beta | 0.00558859 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00557886 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.00556624 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.00556113 |
| GOLM1 | golgi membrane protein 1 | 0.00555666 |
| KRT6A | keratin 6A, type II | 0.00555403 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BGN | biglycan | -0.01285 |
| SIRT3 | sirtuin 3 | -0.0123069 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.0120032 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.011809 |
| FASN | fatty acid synthase | -0.0112788 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0111282 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0110338 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | -0.0108807 |
| DIPK1A | divergent protein kinase domain 1A | -0.0108583 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0102638 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00997165 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00989163 |
| ELN | elastin | -0.00985963 |
| PLSCR3 | phospholipid scramblase 3 | -0.00953776 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00953664 |
| COMP | cartilage oligomeric matrix protein | -0.00933409 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.0091626 |
| FSD1 | fibronectin type III and SPRY domain containing 1 | -0.00908417 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00899217 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00855348 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00823136 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00822206 |
| HTRA1 | HtrA serine peptidase 1 | -0.00820614 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | -0.0081454 |
| EREG | epiregulin | -0.00812612 |
| RTN2 | reticulon 2 | -0.00811395 |
| NID2 | nidogen 2 (osteonidogen) | -0.00808157 |
| SORT1 | sortilin 1 | -0.00806331 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00805483 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00805057 |
| EFHD1 | EF-hand domain family, member D1 | -0.00802894 |
| COL5A1 | collagen, type V, alpha 1 | -0.00792015 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00785907 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.007826 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00782549 |
| SMC1A | structural maintenance of chromosomes 1A | -0.00763704 |
| RTN3 | reticulon 3 | -0.00760591 |
| THY1 | Thy-1 cell surface antigen | -0.00750388 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0075024 |
| XIC | X chromosome inactivation center | -0.00744466 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00739104 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00734828 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00733701 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.00732208 |
| CYBRD1 | cytochrome b reductase 1 | -0.00730454 |
| BIN1 | bridging integrator 1 | -0.00729294 |
| AEBP1 | AE binding protein 1 | -0.00727563 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.0072687 |
| GAS1 | growth arrest-specific 1 | -0.00717531 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00712087 |
| CHKB | choline kinase beta | -0.00702826 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00698703 |
| WASF1 | WAS protein family, member 1 | -0.00692409 |
| PALM | paralemmin | -0.00687623 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.00686557 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00685844 |
| BICC1 | BicC family RNA binding protein 1 | -0.00680525 |
| TIPRL | TOR signaling pathway regulator | -0.00679811 |
| VCAN | versican | -0.00676437 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | -0.00675707 |
| ANO3 | anoctamin 3 | -0.00671075 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00668289 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00666957 |
| WT1 | Wilms tumor 1 | -0.00666673 |
| GPX4 | glutathione peroxidase 4 | -0.00665408 |
| INHBA | inhibin, beta A | -0.0066519 |
| RCAN1 | regulator of calcineurin 1 | -0.00664638 |
| GPR88 | G protein-coupled receptor 88 | -0.00662237 |
| HOXC10 | homeobox C10 | -0.00661814 |
| LRRC15 | leucine rich repeat containing 15 | -0.00658834 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00652488 |
| EHD2 | EH-domain containing 2 | -0.00649082 |
| IL7R | interleukin 7 receptor | -0.00648415 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.00648005 |
| CDC7 | cell division cycle 7 | -0.0063965 |
| ADD3 | adducin 3 (gamma) | -0.00632875 |
| PITX3 | paired-like homeodomain 3 | -0.00630731 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -0.00629173 |
| LRRC17 | leucine rich repeat containing 17 | -0.0062822 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00626929 |
| FBXO11 | F-box protein 11 | -0.00626645 |
| MAMLD1 | mastermind-like domain containing 1 | -0.00625177 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00623496 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) | -0.00622208 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | -0.00621657 |
| CTSZ | cathepsin Z | -0.00621517 |
| DLX2 | distal-less homeobox 2 | -0.00616017 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.00614116 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0061292 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.00612629 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00611998 |
| TCTA | T-cell leukemia translocation altered | -0.0061139 |
| CLIC3 | chloride intracellular channel 3 | -0.00610973 |
| PFKM | phosphofructokinase, muscle | -0.00609837 |
| CCDC85B | coiled-coil domain containing 85B | -0.00609521 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | -0.00609067 |
| CBS | cystathionine-beta-synthase | -0.00602159 |
| CTSK | cathepsin K | -0.00601687 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00600051 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00598759 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.0059745 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00597359 |
| XPO7 | exportin 7 | -0.00596029 |
| FMO1 | flavin containing monooxygenase 1 | -0.00593208 |
| NUCB1 | nucleobindin 1 | -0.00592985 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00591352 |
| MAP7 | microtubule-associated protein 7 | -0.00590464 |
| PLXNB2 | plexin B2 | -0.00590375 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00589724 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | -0.00589304 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00588947 |
| MZB1 | marginal zone B and B1 cell-specific protein | -0.00585809 |
| EXOSC4 | exosome component 4 | -0.00584146 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00581384 |
| FST | follistatin | -0.00580662 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00578702 |
| KAZN | kazrin, periplakin interacting protein | -0.00577887 |
| PKM | pyruvate kinase, muscle | -0.00575703 |
| TRAPPC3 | trafficking protein particle complex 3 | -0.0057537 |
| PSPH | phosphoserine phosphatase | -0.005724 |
| ICAM2 | intercellular adhesion molecule 2 | -0.00570681 |
| PRR16 | proline rich 16 | -0.0056911 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.00565217 |
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | -0.00564848 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | -0.00563552 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00561874 |
| WBP2 | WW domain binding protein 2 | -0.00561541 |
| LOXL1 | lysyl oxidase-like 1 | -0.00561374 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.00560438 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.0056043 |
| PEPD | peptidase D | -0.00560195 |
| GOLIM4 | golgi integral membrane protein 4 | -0.00559253 |
| MGAM | maltase-glucoamylase | -0.00557779 |
| FOXC1 | forkhead box C1 | -0.00557135 |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | -0.00557045 |
| S100A8 | S100 calcium binding protein A8 | -0.00556969 |
| CCNF | cyclin F | -0.00556863 |
| GFAP | glial fibrillary acidic protein | -0.00556282 |
| ARPP21 | cAMP-regulated phosphoprotein, 21kDa | -0.00556176 |
| ZNF329 | zinc finger protein 329 | -0.00554856 |
| RAPSN | receptor-associated protein of the synapse | -0.00554743 |
| SC5D | sterol-C5-desaturase | -0.0055433 |
| VEGFC | vascular endothelial growth factor C | -0.00554122 |
| NINJ2 | ninjurin 2 | -0.00553189 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00552907 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | -0.0055276 |
| BCL7A | B-cell CLL/lymphoma 7A | -0.00551142 |
| GSDME | gasdermin E | -0.00549679 |
| ARHGAP33 | Rho GTPase activating protein 33 | -0.0054865 |
| COL5A2 | collagen, type V, alpha 2 | -0.00548256 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.00546548 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -0.00546087 |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | -0.00545745 |
| PFN2 | profilin 2 | -0.00545296 |
| GAMT | guanidinoacetate N-methyltransferase | -0.00544478 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | -0.0054406 |
| IRX5 | iroquois homeobox 5 | -0.00542752 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -0.00541454 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00540793 |
| CTNS | cystinosin, lysosomal cystine transporter | -0.00540188 |
| NPR3 | natriuretic peptide receptor 3 | -0.00539588 |
| STK38L | serine/threonine kinase 38 like | -0.00537459 |
| PFKL | phosphofructokinase, liver | -0.00536404 |
| IFI30 | interferon, gamma-inducible protein 30 | -0.00535997 |
| MAP1A | microtubule-associated protein 1A | -0.00531065 |
| NADK | NAD kinase | -0.00530445 |
| CCDC47 | coiled-coil domain containing 47 | -0.00530277 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.00529971 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain | -0.00529454 |
| GLS | glutaminase | -0.00527938 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00525306 |
| LAPTM5 | lysosomal protein transmembrane 5 | -0.00523352 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.00523193 |
| SCAND1 | SCAN domain containing 1 | -0.00520576 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00520309 |
| CRIP2 | cysteine-rich protein 2 | -0.00519435 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00519331 |
| KLHDC3 | kelch domain containing 3 | -0.0051884 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.00518426 |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa | -0.00516211 |
| PXDN | peroxidasin | -0.00515433 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | -0.00514563 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -0.00514153 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.00514041 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00513972 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00513318 |
| RAB8A | RAB8A, member RAS oncogene family | -0.00512577 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.0051235 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | -0.00512297 |
| BCL7B | B-cell CLL/lymphoma 7B | -0.0051219 |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 | -0.00512046 |
| DVL2 | dishevelled segment polarity protein 2 | -0.00511284 |
| C6 | complement component 6 | -0.00510934 |
| CA12 | carbonic anhydrase XII | -0.00510708 |
| CD38 | CD38 molecule | -0.00510206 |
| TLK2 | tousled-like kinase 2 | -0.00508625 |
| FAAP100 | FA core complex associated protein 100 | -0.00508478 |
| GTPBP1 | GTP binding protein 1 | -0.0050831 |
| GPX3 | glutathione peroxidase 3 | -0.00507622 |
| CRYM | crystallin, mu | -0.00506117 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | -0.00504292 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -0.00503619 |
| MXRA7 | matrix-remodelling associated 7 | -0.00502869 |
| LAGE3 | L antigen family, member 3 | -0.00501321 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00500667 |
| PRKCZ | protein kinase C, zeta | -0.00500012 |
| PSMC5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | -0.00499957 |
| PMP22 | peripheral myelin protein 22 | -0.00499572 |
| ARRB2 | arrestin, beta 2 | -0.0049913 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00498301 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 | -0.00497855 |
| DESI1 | desumoylating isopeptidase 1 | -0.00497841 |
| GLDC | glycine dehydrogenase (decarboxylating) | -0.00497437 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00496668 |
| UBE2M | ubiquitin-conjugating enzyme E2M | -0.00494766 |
| GPI | glucose-6-phosphate isomerase | -0.00494371 |
| MICU1 | mitochondrial calcium uptake 1 | -0.00493936 |
| TEX30 | testis expressed 30 | -0.00493798 |
| ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 | -0.00492623 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 | -0.00492145 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00492009 |
| DGS2 | DiGeorge syndrome/velocardiofacial syndrome complex 2 | -0.00491851 |
| TSKU | tsukushi, small leucine rich proteoglycan | -0.00490092 |
| SNX6 | sorting nexin 6 | -0.0048986 |
| PIAS4 | protein inhibitor of activated STAT, 4 | -0.0048983 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -0.00489295 |
| CLIP3 | CAP-GLY domain containing linker protein 3 | -0.00489071 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.00488402 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | -0.00488388 |
| PNPLA6 | patatin-like phospholipase domain containing 6 | -0.00486815 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | -0.00486346 |
| GCAT | glycine C-acetyltransferase | -0.00486025 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | -0.00485145 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00484759 |
| SCAMP4 | secretory carrier membrane protein 4 | -0.00483517 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | -0.00482066 |
| DCK | deoxycytidine kinase | -0.00481922 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase | -0.00480053 |
| PMM1 | phosphomannomutase 1 | -0.00479273 |
| SCG5 | secretogranin V | -0.00478728 |
| RBBP8 | retinoblastoma binding protein 8 | -0.00478663 |
| RUNX1 | runt-related transcription factor 1 | -0.00478489 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0047672 |
| NNMT | nicotinamide N-methyltransferase | -0.00476073 |
| TECR | trans-2,3-enoyl-CoA reductase | -0.00474275 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00472843 |
| PENK | proenkephalin | -0.00472048 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00471831 |
