HLA-DQB1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description major histocompatibility complex, class II, DQ beta 1|HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains six exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011] (NCBI Entrez Gene Database, 3119)
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Genes

386 genes differentially expressed following the HLA-DQB1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CFAP70 cilia and flagella associated protein 70 3.3436
RERGL RERG/RAS-like 3.3436
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 3.3436
MMP20 matrix metallopeptidase 20 3.3436
MEIKIN meiotic kinetochore factor 3.3436
MLIP muscular LMNA-interacting protein 3.3436
TMEM150B transmembrane protein 150B 3.3436
HORMAD2 HORMA domain containing 2 3.3436
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit 3.3436
LGALS7B lectin, galactoside-binding, soluble, 7B 3.3436
CSTL1 cystatin-like 1 3.3436
NPPA natriuretic peptide A 3.3436
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 3.3436
MUC1 mucin 1, cell surface associated 3.3436
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 3.3436
GJA4 gap junction protein, alpha 4, 37kDa 3.3436
ERFE erythroferrone 3.3436
GPRC5D G protein-coupled receptor, class C, group 5, member D 3.3436
PCDH20 protocadherin 20 3.3436
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 3.3436
PVALEF parvalbumin like EF-hand containing 3.3436
KCNK15 potassium channel, two pore domain subfamily K, member 15 3.3436
DNAH8 dynein, axonemal, heavy chain 8 3.3436
PANO1 proapoptotic nucleolar protein 1 3.3436
DNAAF8 dynein axonemal assembly factor 8 3.3436
GJB3 gap junction protein, beta 3, 31kDa 3.32092
LRRC52 leucine rich repeat containing 52 3.32092
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 3.32092
RGPD3 RANBP2-like and GRIP domain containing 3 3.32092
CD300A CD300a molecule 3.32092
DHRS9 dehydrogenase/reductase (SDR family) member 9 3.32092
GRXCR2 glutaredoxin, cysteine rich 2 3.32092
SCRT2 scratch family zinc finger 2 3.32092
LYST lysosomal trafficking regulator 3.32092
SCG2 secretogranin II 3.32092
CD1D CD1d molecule 3.32092
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 3.32092
BTC betacellulin 3.32092
ABRA actin binding Rho activating protein 3.32092
FOXA2 forkhead box A2 3.32092
RHOJ ras homolog family member J 3.32092
HGD homogentisate 1,2-dioxygenase 3.32092
HES3 hes family bHLH transcription factor 3 3.32092
PRSS21 protease, serine, 21 (testisin) 3.32092
MSC musculin 3.32092
NEU4 sialidase 4 3.32092
CYSTM1 cysteine-rich transmembrane module containing 1 3.32092
FAM161B family with sequence similarity 161, member B 3.32092
TRPC5OS TRPC5 opposite strand 3.32092
PRDM12 PR domain containing 12 3.32092
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 3.32092
MYL4 myosin, light chain 4, alkali; atrial, embryonic 3.32092
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 3.32092
KIAA1755 KIAA1755 3.32092
LKAAEAR1 LKAAEAR motif containing 1 3.32092
HBZ hemoglobin, zeta 3.32092
GPR101 G protein-coupled receptor 101 3.32092
NUGGC nuclear GTPase, germinal center associated 3.32092
NOTUM notum pectinacetylesterase homolog (Drosophila) 3.32092
GMFG glia maturation factor, gamma 3.32092
TMEM79 transmembrane protein 79 3.32092
RGPD1 RANBP2-like and GRIP domain containing 1 3.32092
CPB1 carboxypeptidase B1 (tissue) 3.32092
SHD Src homology 2 domain containing transforming protein D 3.32092
LRRC63 leucine rich repeat containing 63 3.32092
ANKRD45 ankyrin repeat domain 45 3.32092
LOC107986837 uncharacterized LOC107986837 3.32092
ODAD1 outer dynein arm docking complex subunit 1 3.32092
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 3.32092
TYROBP TYRO protein tyrosine kinase binding protein 3.32092
PLCZ1 phospholipase C, zeta 1 3.32092
PAPOLB poly(A) polymerase beta (testis specific) 3.32092
PIRT phosphoinositide-interacting regulator of transient receptor potential channels 3.32092
MYL10 myosin, light chain 10, regulatory 3.32092
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 3.32092
GATA3 GATA binding protein 3 3.32092
KL klotho 3.32092
CNTN6 contactin 6 3.32092
CCN3 cellular communication network factor 3 3.32092
EPOP elongin BC and polycomb repressive complex 2 associated protein 3.32092
SMIM38 small integral membrane protein 38 3.32092
CIMIP2C ciliary microtubule inner protein 2C 3.32092
TEX53 testis expressed 53 3.32092
SPEGNB SPEG neighbor 3.32092
SMIM45 small integral membrane protein 45 3.32092
LHFPL7 LHFPL tetraspan subfamily member 7 3.32092
CFAP206 cilia and flagella associated protein 206 3.32092
GARIN1A golgi associated RAB2 interactor 1A 3.32092
DUSP29 dual specificity phosphatase 29 3.32092
SPACDR sperm acrosome developmental regulator 3.32092
PLAAT2 phospholipase A and acyltransferase 2 3.32092
CCDC198 coiled-coil domain containing 198 3.32092
DLK1 delta-like 1 homolog (Drosophila) 3.32092
COX8C cytochrome c oxidase subunit VIIIC 3.32092
PCDHA7 protocadherin alpha 7 3.32092
PCDHA6 protocadherin alpha 6 3.32092
IL36G interleukin 36, gamma 3.32092
ATP13A4 ATPase type 13A4 3.32092
SLC22A14 solute carrier family 22, member 14 3.32092
KLHL34 kelch-like family member 34 3.32092
TSSK4 testis-specific serine kinase 4 3.32092
GJA5 gap junction protein, alpha 5, 40kDa 3.32092
GK3 glycerol kinase 3 3.32092
RASL10A RAS-like, family 10, member A 3.32092
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 3.32092
NKX2-6 NK2 homeobox 6 3.32092
WDR38 WD repeat domain 38 3.32092
C4ORF17 chromosome 4 open reading frame 17 3.32092
ALG10B ALG10B, alpha-1,2-glucosyltransferase 3.32092
C7ORF57 chromosome 7 open reading frame 57 3.32092
PGLYRP2 peptidoglycan recognition protein 2 3.32092
SBSN suprabasin 3.32092
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 3.32092
SH3TC1 SH3 domain and tetratricopeptide repeats 1 3.32092
TPTE transmembrane phosphatase with tensin homology 3.32092
TLR6 toll-like receptor 6 3.32092
PPIL6 peptidylprolyl isomerase (cyclophilin)-like 6 3.32092
DSCAML1 Down syndrome cell adhesion molecule like 1 3.32092
OLAH oleoyl-ACP hydrolase 3.32092
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 3.32092
CCL27 chemokine (C-C motif) ligand 27 3.32092
CALHM3 calcium homeostasis modulator 3 3.32092
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 3.32092
APOC4 apolipoprotein C-IV 3.32092
POU2AF1 POU class 2 associating factor 1 3.32092
EMP1 epithelial membrane protein 1 3.32092
MCCD1 mitochondrial coiled-coil domain 1 3.32092
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 3.32092
IL1B interleukin 1, beta 3.32092
TEKT5 tektin 5 3.32092
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B 3.32092
ADAM7 ADAM metallopeptidase domain 7 3.32092
SCT secretin 3.32092
TSNAXIP1 translin-associated factor X interacting protein 1 3.32092
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 3.32092
POF1B premature ovarian failure, 1B 3.32092
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13 3.32092
C11ORF91 chromosome 11 open reading frame 91 3.32092
CLRN3 clarin 3 3.32092
CTAGE4 CTAGE family, member 4 3.32092
SCML4 sex comb on midleg-like 4 (Drosophila) 3.32092
LOXHD1 lipoxygenase homology domains 1 3.32092
TIGD3 tigger transposable element derived 3 3.32092
TTC16 tetratricopeptide repeat domain 16 3.32092
KLK7 kallikrein-related peptidase 7 3.32092
GPR62 G protein-coupled receptor 62 3.32092
DAW1 dynein assembly factor with WDR repeat domains 1 3.32092
NOBOX NOBOX oogenesis homeobox 3.32092
IZUMO1R IZUMO1 receptor, JUNO 3.32092
GPR142 G protein-coupled receptor 142 3.32092
OTP orthopedia homeobox 3.32092
LAMB4 laminin, beta 4 3.32092
LRRN4 leucine rich repeat neuronal 4 3.32092
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 3.32092
ZNF835 zinc finger protein 835 3.32092
GPR61 G protein-coupled receptor 61 3.32092
NT5C1A 5'-nucleotidase, cytosolic IA 3.32092
TBX2 T-box 2 3.32092
CALR3 calreticulin 3 3.32092
BEAN1 brain expressed, associated with NEDD4, 1 3.32092
CTXN2 cortexin 2 3.32092
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 3.32092
RBM24 RNA binding motif protein 24 3.32092
ANKRD53 ankyrin repeat domain 53 3.32092
DMRT3 doublesex and mab-3 related transcription factor 3 3.32092
CLDN34 claudin 34 3.32092
OTOP2 otopetrin 2 3.32092
UPK1B uroplakin 1B 3.32092
TRPM5 transient receptor potential cation channel, subfamily M, member 5 3.32092
HSPB9 heat shock protein, alpha-crystallin-related, B9 3.32092
CIDEA cell death-inducing DFFA-like effector a 3.32092
OR51I2 olfactory receptor, family 51, subfamily I, member 2 3.32092
ONECUT3 one cut homeobox 3 3.32092
KRT15 keratin 15, type I 3.32092
ANXA1 annexin A1 3.32092
ANGPTL5 angiopoietin-like 5 3.32092
GCSAML germinal center-associated, signaling and motility-like 3.32092
PPP1R3G protein phosphatase 1, regulatory subunit 3G 3.32092
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 3.32092
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 3.32092
GRAPL GRB2-related adaptor protein-like 3.32092
DMRTC2 DMRT-like family C2 3.32092
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 3.32092
NPAS4 neuronal PAS domain protein 4 3.32092
MT1M metallothionein 1M 3.32092
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 3.32092
CLCNKA chloride channel, voltage-sensitive Ka 3.32092
FAM25G family with sequence similarity 25, member G 3.32092
TBC1D28 TBC1 domain family, member 28 3.32092
RAB7B RAB7B, member RAS oncogene family 3.32092
PCDHGB4 protocadherin gamma subfamily B, 4 3.32092
ICAM2 intercellular adhesion molecule 2 3.32092
MSLN mesothelin 3.32092
PCDHGB2 protocadherin gamma subfamily B, 2 3.32092
NPIPB15 nuclear pore complex interacting protein family, member B15 3.32092
DCST1 DC-STAMP domain containing 1 3.32092
EPYC epiphycan 3.32092
ZC3H11B zinc finger CCCH-type containing 11B pseudogene 3.32092
EFCAB11 EF-hand calcium binding domain 11 3.31349
LINGO1 leucine rich repeat and Ig domain containing 1 3.23318
PDCL2 phosducin-like 2 3.19412
SMOC1 SPARC related modular calcium binding 1 3.15134
RGS14 regulator of G-protein signaling 14 3.10791
CLIC1 chloride intracellular channel 1 3.05881
TOP6BL TOP6B like initiator of meiotic double strand breaks 3.02229
TBCK TBC1 domain containing kinase 2.948
WHRN whirlin 2.91863
XNDC1N XRCC1 N-terminal domain containing 1, N-terminal like 2.90667
YLPM1 YLP motif containing 1 2.89879
FGF22 fibroblast growth factor 22 2.8569
TAGLN transgelin 2.77664
TEX2 testis expressed 2 2.62438
UNG uracil-DNA glycosylase 2.59565
ZNF621 zinc finger protein 621 2.57013
LIMS2 LIM and senescent cell antigen-like domains 2 2.56978
SF3B4 splicing factor 3b, subunit 4, 49kDa 2.55147
ZNF878 zinc finger protein 878 2.54212
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 2.52483
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 2.51793
C1ORF159 chromosome 1 open reading frame 159 2.50322
ZNF429 zinc finger protein 429 2.50322
CAGE1 cancer antigen 1 2.49459
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 2.46148
PBRM1 polybromo 1 2.43744
ACOX3 acyl-CoA oxidase 3, pristanoyl 2.41814
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 2.41814
CRTC1 CREB regulated transcription coactivator 1 2.41657
SATL1 spermidine/spermine N1-acetyl transferase-like 1 2.4047
EYA2 EYA transcriptional coactivator and phosphatase 2 2.38971
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 2.36394
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 2.35467
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 2.35055
ZCCHC17 zinc finger, CCHC domain containing 17 2.30471
KRABD4 KRAB domain containing 4 2.29451
ATM ATM serine/threonine kinase 2.29016
NFE2L3 nuclear factor, erythroid 2-like 3 2.28825
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 2.28768
IGFBP7 insulin-like growth factor binding protein 7 2.2775
ACO2 aconitase 2, mitochondrial 2.2775
ENTREP1 endosomal transmembrane epsin interactor 1 2.25023
OTUD5 OTU deubiquitinase 5 2.25023
THAP8 THAP domain containing 8 2.24319
C17ORF58 chromosome 17 open reading frame 58 2.23952
ASXL1 additional sex combs like transcriptional regulator 1 2.22127
TOX2 TOX high mobility group box family member 2 2.2201
MSTO1 misato 1, mitochondrial distribution and morphology regulator 2.19914
ADA2 adenosine deaminase 2 2.18742
LURAP1 leucine rich adaptor protein 1 2.18156
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 2.17765
FBF1 Fas (TNFRSF6) binding factor 1 2.17765
RHOG ras homolog family member G 2.17715
ANKRD54 ankyrin repeat domain 54 2.16282
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.13395
PHOSPHO2-KLHL23 PHOSPHO2-KLHL23 readthrough 2.11259
GRPEL1 GrpE-like 1, mitochondrial (E. coli) 2.10277
BTBD7 BTB (POZ) domain containing 7 2.08952
UPK1A uroplakin 1A 2.08407
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 2.08407
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 2.08407
CCNH cyclin H 2.06287
SHFL shiftless antiviral inhibitor of ribosomal frameshifting 2.05908
SMIM7 small integral membrane protein 7 2.05908
LIMA1 LIM domain and actin binding 1 2.04293
DNM2 dynamin 2 2.04293
TBC1D14 TBC1 domain family, member 14 2.03668
PEDS1 plasmanylethanolamine desaturase 1 2.02818
ZFHX3 zinc finger homeobox 3 2.02215
RNF217 ring finger protein 217 2.01421
ZNF443 zinc finger protein 443 2.01168
SCFD2 sec1 family domain containing 2 2.00937
ADAR adenosine deaminase, RNA-specific 2.00937
NFASC neurofascin 2.00641
RANBP9 RAN binding protein 9 2.00597
ENDOG endonuclease G 2.00597
USP49 ubiquitin specific peptidase 49 2.00597
OXSR1 oxidative stress responsive 1 2.00313
PLCH1 phospholipase C, eta 1 2.00313
YPEL2 yippee-like 2 (Drosophila) 2.00274

decreased expression

Symbol Name Standardized Value
FBP2 fructose-1,6-bisphosphatase 2 -3.3436
CFAP90 cilia and flagella associated protein 90 -3.3436
OR4D1 olfactory receptor, family 4, subfamily D, member 1 -3.3436
HSPB2 heat shock 27kDa protein 2 -3.3436
ADPRH ADP-ribosylarginine hydrolase -3.3436
FCRL5 Fc receptor-like 5 -3.32092
IL4I1 interleukin 4 induced 1 -3.32092
TMPRSS11E transmembrane protease, serine 11E -3.32092
SBK2 SH3 domain binding kinase family, member 2 -3.32092
SHISAL2A shisa like 2A -3.32092
FAM50B family with sequence similarity 50, member B -3.32092
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 -3.32092
ZNF703 zinc finger protein 703 -3.32092
KIAA2012 KIAA2012 -3.32092
OVCH1 ovochymase 1 -3.32092
NLRX1 NLR family member X1 -3.32092
OR14A16 olfactory receptor, family 14, subfamily A, member 16 -3.32092
TGM2 transglutaminase 2 -3.32092
CELA2B chymotrypsin-like elastase family, member 2B -3.32092
ITLN2 intelectin 2 -3.32092
TEKT2 tektin 2 (testicular) -3.32092
FPR3 formyl peptide receptor 3 -3.32092
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 -3.32092
DUSP8 dual specificity phosphatase 8 -3.32092
ABI3 ABI family, member 3 -3.32092
RIPK4 receptor-interacting serine-threonine kinase 4 -3.32092
RAG1 recombination activating gene 1 -3.32092
TTC22 tetratricopeptide repeat domain 22 -3.32092
GOLGA8T golgin A8 family, member T -3.32092
PALS1 protein associated with LIN7 1, MAGUK p55 family member -3.32092
ATP5MGL ATP synthase membrane subunit g like -3.32092
LPIN3 lipin 3 -3.32092
CFAP126 cilia and flagella associated protein 126 -3.32092
MYH7B myosin, heavy chain 7B, cardiac muscle, beta -3.32092
MYO18B myosin XVIIIB -3.32092
TLR3 toll-like receptor 3 -3.32092
CFAP61 cilia and flagella associated protein 61 -3.32092
RNF113B ring finger protein 113B -3.32092
CCDC7 coiled-coil domain containing 7 -3.21211
THRAP3 thyroid hormone receptor associated protein 3 -2.93856
PNPLA3 patatin-like phospholipase domain containing 3 -2.86923
PMM1 phosphomannomutase 1 -2.74909
NDRG4 NDRG family member 4 -2.73732
PTCHD4 patched domain containing 4 -2.73058
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 -2.73052
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -2.71637
ADAM17 ADAM metallopeptidase domain 17 -2.68024
ZNF44 zinc finger protein 44 -2.64299
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) -2.64299
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) -2.62657
MASTL microtubule associated serine/threonine kinase-like -2.55487
PDPN podoplanin -2.53828
SIVA1 SIVA1, apoptosis-inducing factor -2.53008
CASP9 caspase 9, apoptosis-related cysteine peptidase -2.49835
PCDH17 protocadherin 17 -2.43744
KLK13 kallikrein-related peptidase 13 -2.43744
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 -2.43744
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -2.42211
TBP TATA box binding protein -2.42128
FSD2 fibronectin type III and SPRY domain containing 2 -2.4047
PP2D1 protein phosphatase 2C-like domain containing 1 -2.4047
IKZF5 IKAROS family zinc finger 5 (Pegasus) -2.39978
BIN1 bridging integrator 1 -2.36905
JPH2 junctophilin 2 -2.34891
KLF5 Kruppel-like factor 5 (intestinal) -2.34891
SNX22 sorting nexin 22 -2.33198
SYNPO2L synaptopodin 2-like -2.33198
PDLIM2 PDZ and LIM domain 2 (mystique) -2.32699
SLITRK5 SLIT and NTRK-like family, member 5 -2.31727
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -2.29451
RGPD8 RANBP2-like and GRIP domain containing 8 -2.29065
DPP9 dipeptidyl-peptidase 9 -2.28352
GFM2 G elongation factor, mitochondrial 2 -2.25594
SEPTIN5 septin 5 -2.25594
TBC1D5 TBC1 domain family, member 5 -2.25111
TMEM144 transmembrane protein 144 -2.24601
MCM10 minichromosome maintenance complex component 10 -2.22262
ZNF571 zinc finger protein 571 -2.20646
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 -2.20084
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -2.19757
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -2.18742
CFD complement factor D (adipsin) -2.17765
CCDC175 coiled-coil domain containing 175 -2.17765
PGAP4 post-GPI attachment to proteins GalNAc transferase 4 -2.16171
MTG2 mitochondrial ribosome-associated GTPase 2 -2.13515
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -2.0945
B3GAT1 beta-1,3-glucuronyltransferase 1 -2.08407
ICA1L islet cell autoantigen 1,69kDa-like -2.06287
ZNF143 zinc finger protein 143 -2.06027
RNF6 ring finger protein (C3H2C3 type) 6 -2.05908
ZNF607 zinc finger protein 607 -2.05223
ATG16L2 autophagy related 16-like 2 (S. cerevisiae) -2.04416
RNF145 ring finger protein 145 -2.04293
ACSL4 acyl-CoA synthetase long-chain family member 4 -2.03668
TYMS thymidylate synthetase -2.02818
GSTO2 glutathione S-transferase omega 2 -2.02634
STARD9 StAR-related lipid transfer (START) domain containing 9 -2.02243
DENND2C DENN/MADD domain containing 2C -2.02005
DVL2 dishevelled segment polarity protein 2 -2.00937
DPEP3 dipeptidase 3 -2.00937
CPLX2 complexin 2 -2.00937
OTX2 orthodenticle homeobox 2 -2.00937
CDH18 cadherin 18, type 2 -2.00937
SRRM3 serine/arginine repetitive matrix 3 -2.0066
SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4 -2.00641
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 -2.00313
SCRIB scribbled planar cell polarity protein -2.00313
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.00004