| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | major histocompatibility complex, class II, DQ beta 2|HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus. [provided by RefSeq, Oct 2010] (NCBI Entrez Gene Database, 3120) |
| External Link | https://ncbi.nlm.nih.gov/gene/3120 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the HLA-DQB2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| XPO7 | exportin 7 | 0.0188301 |
| MAP7 | microtubule-associated protein 7 | 0.0159019 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.0126619 |
| CHGB | chromogranin B | 0.012391 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0101592 |
| PLCB4 | phospholipase C, beta 4 | 0.0100981 |
| TEX10 | testis expressed 10 | 0.00997922 |
| KRT18 | keratin 18, type I | 0.00940649 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00911973 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00891486 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.00868369 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00849832 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00833475 |
| MGP | matrix Gla protein | 0.00829594 |
| RGS5 | regulator of G-protein signaling 5 | 0.00797149 |
| KRT14 | keratin 14, type I | 0.00796121 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00791897 |
| SNX7 | sorting nexin 7 | 0.00786835 |
| ACTB | actin, beta | 0.00786092 |
| GNAS | GNAS complex locus | 0.00777005 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) | 0.00761086 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.00756866 |
| RHOB | ras homolog family member B | 0.00756764 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00745545 |
| BEX1 | brain expressed, X-linked 1 | 0.0074266 |
| TLK2 | tousled-like kinase 2 | 0.00736142 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00712623 |
| RXYLT1 | ribitol xylosyltransferase 1 | 0.00712098 |
| RNF167 | ring finger protein 167 | 0.00709955 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.0070708 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00705994 |
| CCN2 | cellular communication network factor 2 | 0.00703615 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00702565 |
| RET | ret proto-oncogene | 0.00698425 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 0.00697372 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.00689785 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0068569 |
| CHPT1 | choline phosphotransferase 1 | 0.00681082 |
| TCTA | T-cell leukemia translocation altered | 0.0067603 |
| CD27 | CD27 molecule | 0.00674935 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00674759 |
| ANGPT1 | angiopoietin 1 | 0.00673681 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 0.00671857 |
| PRMT1 | protein arginine methyltransferase 1 | 0.00669758 |
| FAR2 | fatty acyl CoA reductase 2 | 0.00664648 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | 0.00654752 |
| CDC20 | cell division cycle 20 | 0.00653447 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00649046 |
| PTTG1 | pituitary tumor-transforming 1 | 0.0064465 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | 0.0063842 |
| ODAM | odontogenic, ameloblast asssociated | 0.00636884 |
| FERMT1 | fermitin family member 1 | 0.00634694 |
| ARHGAP44 | Rho GTPase activating protein 44 | 0.0063418 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00632637 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00630694 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00626392 |
| NEFM | neurofilament, medium polypeptide | 0.00625238 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | 0.00623381 |
| SPRR1B | small proline-rich protein 1B | 0.00621211 |
| CADM1 | cell adhesion molecule 1 | 0.00620069 |
| INSR | insulin receptor | 0.00618649 |
| STOM | stomatin | 0.00616313 |
| STMN2 | stathmin 2 | 0.00614509 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.00613226 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00610621 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | 0.00610506 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0060866 |
| NRIP3 | nuclear receptor interacting protein 3 | 0.0060246 |
| CCNC | cyclin C | 0.00602416 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 0.0059987 |
| AIM2 | absent in melanoma 2 | 0.00599543 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.005988 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00597739 |
| PLSCR3 | phospholipid scramblase 3 | 0.0059606 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00595217 |
| MAGEA12 | melanoma antigen family A12 | 0.00594566 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.00593149 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.00586932 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.00584393 |
| CHI3L2 | chitinase 3-like 2 | 0.00579087 |
| CTSC | cathepsin C | 0.00577493 |
| SCAMP1 | secretory carrier membrane protein 1 | 0.00576656 |
| VAMP5 | vesicle-associated membrane protein 5 | 0.00575345 |
| JAM3 | junctional adhesion molecule 3 | 0.0057456 |
| MT1X | metallothionein 1X | 0.00574291 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00572692 |
| EDN3 | endothelin 3 | 0.00569778 |
| MAB21L1 | mab-21-like 1 (C. elegans) | 0.00569249 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00566657 |
| NEBL | nebulette | 0.00566403 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.00566169 |
| SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 | 0.00564908 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00561974 |
| PDHX | pyruvate dehydrogenase complex, component X | 0.00560896 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | 0.0056067 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.00560088 |
| SIRT3 | sirtuin 3 | 0.00558199 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.0055676 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.00556053 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00555829 |
| TRAPPC3 | trafficking protein particle complex 3 | 0.00555638 |
| COCH | cochlin | 0.0055478 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 0.00553949 |
| NKX2-1 | NK2 homeobox 1 | 0.0055242 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00551951 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | 0.00550119 |
| RRM1 | ribonucleotide reductase M1 | 0.00549862 |
| CHEK1 | checkpoint kinase 1 | 0.00549785 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | 0.00546771 |
| ZNF750 | zinc finger protein 750 | 0.00545773 |
| TMCC2 | transmembrane and coiled-coil domain family 2 | 0.00545643 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.0054419 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | 0.00544138 |
| ABHD17B | abhydrolase domain containing 17B | 0.00543713 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00543374 |
| EFNA1 | ephrin-A1 | 0.00541846 |
| TPX2 | TPX2, microtubule-associated | 0.0054108 |
| ZWILCH | zwilch kinetochore protein | 0.00540738 |
| MT1G | metallothionein 1G | 0.00540454 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | 0.00540246 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00539718 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.0053913 |
| CCNA2 | cyclin A2 | 0.00536187 |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 | 0.00535009 |
| PRDX1 | peroxiredoxin 1 | 0.00533462 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00532953 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00531899 |
| CAPN7 | calpain 7 | 0.00531798 |
| TH | tyrosine hydroxylase | 0.00531651 |
| ERP44 | endoplasmic reticulum protein 44 | 0.00530771 |
| S100A14 | S100 calcium binding protein A14 | 0.00530462 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0052943 |
| UGT8 | UDP glycosyltransferase 8 | 0.00528525 |
| NFIB | nuclear factor I/B | 0.00528249 |
| QRSL1 | glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 | 0.00527644 |
| RBM34 | RNA binding motif protein 34 | 0.00524765 |
| MRPL23 | mitochondrial ribosomal protein L23 | 0.00524314 |
| ZNF430 | zinc finger protein 430 | 0.00523955 |
| RBPMS | RNA binding protein with multiple splicing | 0.00523882 |
| MT1H | metallothionein 1H | 0.00522398 |
| PLS3 | plastin 3 | 0.00522391 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00522301 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00522221 |
| PROM1 | prominin 1 | 0.00519862 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.00519646 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00519099 |
| FSD1 | fibronectin type III and SPRY domain containing 1 | 0.00518479 |
| NRCAM | neuronal cell adhesion molecule | 0.00516132 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.00515279 |
| MED6 | mediator complex subunit 6 | 0.00514608 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00514117 |
| TUBD1 | tubulin, delta 1 | 0.00512945 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.00510421 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00509562 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.00509541 |
| C9ORF3 | chromosome 9 open reading frame 3 | 0.00509423 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00508649 |
| PUM2 | pumilio RNA-binding family member 2 | 0.00508421 |
| PEG10 | paternally expressed 10 | 0.00508018 |
| BUD23 | BUD23 rRNA methyltransferase and ribosome maturation factor | 0.00507971 |
| ACAA2 | acetyl-CoA acyltransferase 2 | 0.00507342 |
| MAGEA3 | melanoma antigen family A3 | 0.00505495 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.00505414 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.00505079 |
| NOVA1 | neuro-oncological ventral antigen 1 | 0.00505037 |
| USP34 | ubiquitin specific peptidase 34 | 0.0050478 |
| NFASC | neurofascin | 0.00504525 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | 0.00504261 |
| ESD | esterase D | 0.00504139 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00504111 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.0050338 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00502703 |
| FGF13 | fibroblast growth factor 13 | 0.0050158 |
| BSG | basigin (Ok blood group) | 0.00501152 |
| RBMX | RNA binding motif protein, X-linked | 0.00501084 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.00499597 |
| INA | internexin neuronal intermediate filament protein, alpha | 0.00499092 |
| BMP2 | bone morphogenetic protein 2 | 0.00498826 |
| TFF1 | trefoil factor 1 | 0.00497993 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00496411 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.00496273 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.00495131 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.00494913 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00492763 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | 0.00491653 |
| GSTA4 | glutathione S-transferase alpha 4 | 0.00491038 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.00490893 |
| LUM | lumican | 0.00490849 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00490708 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | 0.00490395 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00489846 |
| IGSF1 | immunoglobulin superfamily, member 1 | 0.0048969 |
| AURKB | aurora kinase B | 0.00489479 |
| XYLT1 | xylosyltransferase I | 0.00489102 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.00488595 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor | 0.0048803 |
| ANKRD28 | ankyrin repeat domain 28 | 0.00487585 |
| S100A7 | S100 calcium binding protein A7 | 0.00486669 |
| KRT16 | keratin 16, type I | 0.004862 |
| CA4 | carbonic anhydrase IV | 0.00485652 |
| TMEM45A | transmembrane protein 45A | 0.00485271 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.00485095 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.00484987 |
| ROPN1B | rhophilin associated tail protein 1B | 0.00483058 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.00482636 |
| GAB2 | GRB2-associated binding protein 2 | 0.00482142 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | 0.00481121 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00481006 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00480835 |
| SNRPA | small nuclear ribonucleoprotein polypeptide A | 0.00480638 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.00480085 |
| CLCA2 | chloride channel accessory 2 | 0.00479101 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00476796 |
| TG | thyroglobulin | 0.00476404 |
| TENM1 | teneurin transmembrane protein 1 | 0.00475868 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | 0.00471773 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.00471663 |
| PCNA | proliferating cell nuclear antigen | 0.00471089 |
| FLT3 | fms-related tyrosine kinase 3 | 0.00470836 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 0.00470718 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00470592 |
| SLC26A4 | solute carrier family 26 (anion exchanger), member 4 | 0.0046983 |
| RGS16 | regulator of G-protein signaling 16 | 0.00467869 |
| ACSL6 | acyl-CoA synthetase long-chain family member 6 | 0.0046784 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.00467759 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | 0.00467642 |
| RABAC1 | Rab acceptor 1 (prenylated) | 0.00467603 |
| TRIB3 | tribbles pseudokinase 3 | 0.00467386 |
| RETREG1 | reticulophagy regulator 1 | 0.00466733 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00465066 |
| L1CAM | L1 cell adhesion molecule | 0.00464948 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00464786 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | 0.00463954 |
| MRPL42 | mitochondrial ribosomal protein L42 | 0.00463253 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00462316 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00462224 |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) | 0.00462037 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00461357 |
| TBCA | tubulin folding cofactor A | 0.00460622 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.00459731 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00459137 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.00458789 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.00458286 |
| TMEM135 | transmembrane protein 135 | 0.00457926 |
| RGS1 | regulator of G-protein signaling 1 | 0.00457517 |
| DSC2 | desmocollin 2 | 0.00456523 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00456065 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00454279 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | 0.00453079 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BMP4 | bone morphogenetic protein 4 | -0.0134513 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.0126601 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0123164 |
| ANXA1 | annexin A1 | -0.0121125 |
| LYPD1 | LY6/PLAUR domain containing 1 | -0.0118881 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.0117069 |
| TRIB2 | tribbles pseudokinase 2 | -0.0113744 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0109263 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.0108581 |
| IL1R1 | interleukin 1 receptor, type I | -0.0106453 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.010616 |
| THBS1 | thrombospondin 1 | -0.010473 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.0102171 |
| WT1 | Wilms tumor 1 | -0.00984617 |
| MSLN | mesothelin | -0.00982436 |
| CFI | complement factor I | -0.00976609 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00965761 |
| MUC16 | mucin 16, cell surface associated | -0.00963689 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00943269 |
| FOLR1 | folate receptor 1 (adult) | -0.00933039 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00929575 |
| PLAT | plasminogen activator, tissue | -0.00928512 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.00925829 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00903092 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00878787 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00872156 |
| CFB | complement factor B | -0.00865756 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00859754 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00845431 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00843241 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00833663 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00818854 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00811161 |
| MLPH | melanophilin | -0.00809153 |
| LCN2 | lipocalin 2 | -0.00807296 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00806106 |
| GRAMD1C | GRAM domain containing 1C | -0.00803293 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.00799704 |
| PIR | pirin (iron-binding nuclear protein) | -0.0079482 |
| SPON1 | spondin 1, extracellular matrix protein | -0.0077105 |
| C3 | complement component 3 | -0.0076895 |
| MATN2 | matrilin 2 | -0.00754277 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00753905 |
| IL1RN | interleukin 1 receptor antagonist | -0.00753624 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00750893 |
| G0S2 | G0/G1 switch 2 | -0.00749946 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00747832 |
| AHR | aryl hydrocarbon receptor | -0.00747441 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00742614 |
| SYBU | syntabulin (syntaxin-interacting) | -0.00740096 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00739013 |
| CLGN | calmegin | -0.00736326 |
| MECOM | MDS1 and EVI1 complex locus | -0.00736142 |
| HBB | hemoglobin, beta | -0.00733293 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00732776 |
| HOXB6 | homeobox B6 | -0.00724851 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00723032 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00717925 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | -0.00717853 |
| STC2 | stanniocalcin 2 | -0.00712723 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -0.00709844 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00697187 |
| IL7R | interleukin 7 receptor | -0.00694698 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.00692015 |
| ESR1 | estrogen receptor 1 | -0.00691719 |
| AQP9 | aquaporin 9 | -0.00689176 |
| GPR137B | G protein-coupled receptor 137B | -0.00686902 |
| PKP2 | plakophilin 2 | -0.00686826 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00681469 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00680928 |
| RTN2 | reticulon 2 | -0.00678735 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00676627 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00674987 |
| EMP1 | epithelial membrane protein 1 | -0.00673908 |
| COPS7A | COP9 signalosome subunit 7A | -0.00673649 |
| HTRA1 | HtrA serine peptidase 1 | -0.00672635 |
| DAXX | death-domain associated protein | -0.00665911 |
| ANXA4 | annexin A4 | -0.00664568 |
| C5AR1 | complement component 5a receptor 1 | -0.0066399 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00657514 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -0.00654741 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00654129 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 | -0.00653594 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.00647603 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.00641208 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00640161 |
| SMPX | small muscle protein, X-linked | -0.00638088 |
| ASRGL1 | asparaginase like 1 | -0.00635936 |
| AGRN | agrin | -0.00634884 |
| CA2 | carbonic anhydrase II | -0.00631396 |
| ZNF423 | zinc finger protein 423 | -0.00630807 |
| MYRF | myelin regulatory factor | -0.00629322 |
| TCF21 | transcription factor 21 | -0.00627851 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00627076 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.0062587 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.00625832 |
| ATXN10 | ataxin 10 | -0.00624447 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00624401 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.00622023 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.00619482 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | -0.00618889 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00618563 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00618438 |
| IPO13 | importin 13 | -0.00617704 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | -0.00617421 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0061309 |
| SRGN | serglycin | -0.00610043 |
| TOB1 | transducer of ERBB2, 1 | -0.00608168 |
| EPS8L1 | EPS8-like 1 | -0.00608088 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00607637 |
| BCHE | butyrylcholinesterase | -0.00604586 |
| CNTN1 | contactin 1 | -0.00604324 |
| RTN3 | reticulon 3 | -0.00603574 |
| S100A9 | S100 calcium binding protein A9 | -0.00603376 |
| SYNGR2 | synaptogyrin 2 | -0.00602753 |
| JAG1 | jagged 1 | -0.00601644 |
| HOXB2 | homeobox B2 | -0.0059733 |
| H1-2 | H1.2 linker histone, cluster member | -0.00596803 |
| TLN1 | talin 1 | -0.00595279 |
| EPYC | epiphycan | -0.00592705 |
| GMPR | guanosine monophosphate reductase | -0.00592446 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00590441 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00586842 |
| NMU | neuromedin U | -0.0058618 |
| DOK5 | docking protein 5 | -0.0058595 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00585881 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00585772 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00584427 |
| CDK14 | cyclin-dependent kinase 14 | -0.00582875 |
| CD83 | CD83 molecule | -0.00581187 |
| FLNC | filamin C, gamma | -0.0058027 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00579882 |
| PSPH | phosphoserine phosphatase | -0.00579853 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00579117 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -0.00577568 |
| PYGL | phosphorylase, glycogen, liver | -0.00577512 |
| ANXA2 | annexin A2 | -0.00573221 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | -0.00571698 |
| CTH | cystathionine gamma-lyase | -0.00571412 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.00567892 |
| NCKAP1 | NCK-associated protein 1 | -0.00563792 |
| MMP19 | matrix metallopeptidase 19 | -0.00560171 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00559537 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | -0.00559038 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00557355 |
| MMD | monocyte to macrophage differentiation-associated | -0.00556076 |
| STXBP2 | syntaxin binding protein 2 | -0.00554549 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00552065 |
| PAK1IP1 | PAK1 interacting protein 1 | -0.00551151 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00550138 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.00548244 |
| PFKM | phosphofructokinase, muscle | -0.00548074 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.00545136 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00544304 |
| PXN | paxillin | -0.00543569 |
| GCHFR | GTP cyclohydrolase I feedback regulator | -0.00543553 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | -0.00542317 |
| PDZK1 | PDZ domain containing 1 | -0.00541831 |
| TSPAN8 | tetraspanin 8 | -0.00541442 |
| ZNF217 | zinc finger protein 217 | -0.00540341 |
| IER5 | immediate early response 5 | -0.00536534 |
| RAI2 | retinoic acid induced 2 | -0.00535489 |
| CBS | cystathionine-beta-synthase | -0.00535224 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | -0.00535036 |
| TFRC | transferrin receptor | -0.0053501 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | -0.00534318 |
| PLEC | plectin | -0.00533947 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00531122 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00530313 |
| AK4 | adenylate kinase 4 | -0.00529598 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.005288 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0052804 |
| SNAI2 | snail family zinc finger 2 | -0.00528034 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00527547 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00527456 |
| SPP1 | secreted phosphoprotein 1 | -0.0052531 |
| PMM1 | phosphomannomutase 1 | -0.00525042 |
| NLRP2 | NLR family, pyrin domain containing 2 | -0.00524474 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.0052386 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00522858 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.00522519 |
| WLS | wntless Wnt ligand secretion mediator | -0.00522025 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00521382 |
| USP25 | ubiquitin specific peptidase 25 | -0.00520852 |
| UPK1B | uroplakin 1B | -0.00519839 |
| RESF1 | retroelement silencing factor 1 | -0.00519205 |
| KAT2B | K(lysine) acetyltransferase 2B | -0.00519038 |
| KLHL2 | kelch-like family member 2 | -0.00518347 |
| SOX17 | SRY (sex determining region Y)-box 17 | -0.00517535 |
| TGFB1 | transforming growth factor, beta 1 | -0.00516811 |
| MPC2 | mitochondrial pyruvate carrier 2 | -0.0051589 |
| C7 | complement component 7 | -0.00515136 |
| MYBPC2 | myosin binding protein C, fast type | -0.00513317 |
| ADD3 | adducin 3 (gamma) | -0.00513181 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00511723 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.0051147 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0050956 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00508855 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00508745 |
| GPC1 | glypican 1 | -0.00507949 |
| NPAS2 | neuronal PAS domain protein 2 | -0.00507529 |
| PRAME | preferentially expressed antigen in melanoma | -0.00507286 |
| KLK8 | kallikrein-related peptidase 8 | -0.00506781 |
| ZNF12 | zinc finger protein 12 | -0.0050582 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00505791 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.00504299 |
| EGR2 | early growth response 2 | -0.00502184 |
| PLXNB2 | plexin B2 | -0.0050141 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00499801 |
| PTN | pleiotrophin | -0.00497959 |
| PEX6 | peroxisomal biogenesis factor 6 | -0.00497858 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00497817 |
| EMP3 | epithelial membrane protein 3 | -0.00497334 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00496954 |
| FHOD3 | formin homology 2 domain containing 3 | -0.00496161 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00495476 |
| APOD | apolipoprotein D | -0.00494889 |
| PLEK | pleckstrin | -0.00493625 |
| HIST1H2BH | histone cluster 1, H2bh | -0.00493328 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00492808 |
| AOC1 | amine oxidase, copper containing 1 | -0.00490955 |
| QKI | QKI, KH domain containing, RNA binding | -0.004889 |
| LIF | leukemia inhibitory factor | -0.00488736 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00488298 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.00488251 |
| MB | myoglobin | -0.0048805 |
| RAD54B | RAD54 homolog B (S. cerevisiae) | -0.00486381 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00486369 |
| RNF19B | ring finger protein 19B | -0.00486291 |
| CLC | Charcot-Leyden crystal galectin | -0.00485965 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.00485642 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 | -0.00484377 |
| PBLD | phenazine biosynthesis-like protein domain containing | -0.00483143 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00482604 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00482359 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | -0.00482094 |
| ANXA10 | annexin A10 | -0.00481187 |
| VEGFB | vascular endothelial growth factor B | -0.00480993 |
| EVI2A | ecotropic viral integration site 2A | -0.00480377 |
| S100A4 | S100 calcium binding protein A4 | -0.00479644 |
| CRIP2 | cysteine-rich protein 2 | -0.00477353 |
| CFD | complement factor D (adipsin) | -0.00477052 |
| COL5A1 | collagen, type V, alpha 1 | -0.00476787 |
| FBLN1 | fibulin 1 | -0.00475679 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00475439 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00475302 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00472794 |
| PDGFC | platelet derived growth factor C | -0.00472107 |
| DES | desmin | -0.00471995 |
