| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | major histocompatibility complex, class II, DR alpha|HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3122) |
| External Link | https://ncbi.nlm.nih.gov/gene/3122 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the HLA-DRA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | 0.0181986 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0128738 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.012122 |
| GPX3 | glutathione peroxidase 3 | 0.0119285 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.0117896 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0112991 |
| IPO13 | importin 13 | 0.0110054 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.01089 |
| METTL7A | methyltransferase like 7A | 0.00943145 |
| TSPAN4 | tetraspanin 4 | 0.00942002 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00918928 |
| OLFM4 | olfactomedin 4 | 0.00910943 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00902784 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00886785 |
| DCLK1 | doublecortin-like kinase 1 | 0.00881023 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.00858308 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.0085527 |
| ADIRF | adipogenesis regulatory factor | 0.00842252 |
| IRS1 | insulin receptor substrate 1 | 0.00839451 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00835468 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00812796 |
| APOD | apolipoprotein D | 0.00812775 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00810379 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.0080624 |
| STK39 | serine threonine kinase 39 | 0.00801639 |
| TNS1 | tensin 1 | 0.00778108 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00776725 |
| KRT7 | keratin 7, type II | 0.00776359 |
| CFH | complement factor H | 0.00759185 |
| SCAND1 | SCAN domain containing 1 | 0.00757511 |
| RBPMS | RNA binding protein with multiple splicing | 0.0075182 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00746696 |
| CHRDL1 | chordin-like 1 | 0.00740254 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | 0.00732107 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 0.00722221 |
| RXYLT1 | ribitol xylosyltransferase 1 | 0.00720419 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.00714555 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00698976 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00698195 |
| CLEC3B | C-type lectin domain family 3, member B | 0.0069182 |
| MTCL1 | microtubule crosslinking factor 1 | 0.00691297 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.0069096 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00687124 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00681981 |
| TMEM106B | transmembrane protein 106B | 0.00681192 |
| RGS5 | regulator of G-protein signaling 5 | 0.00671065 |
| TSPYL5 | TSPY-like 5 | 0.0066538 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00662785 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.00661831 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00661168 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.00660647 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00657237 |
| XPO7 | exportin 7 | 0.00655598 |
| GLUD1 | glutamate dehydrogenase 1 | 0.00654973 |
| PLXNB2 | plexin B2 | 0.00649522 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00648519 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00646408 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | 0.00643192 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00634192 |
| PHF20 | PHD finger protein 20 | 0.00633886 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00631152 |
| MXRA8 | matrix-remodelling associated 8 | 0.00627731 |
| LTBP4 | latent transforming growth factor beta binding protein 4 | 0.00625717 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00624403 |
| TGM2 | transglutaminase 2 | 0.00620342 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00619805 |
| C2CD5 | C2 calcium-dependent domain containing 5 | 0.00619554 |
| WWOX | WW domain containing oxidoreductase | 0.00618363 |
| CHMP4A | charged multivesicular body protein 4A | 0.00617345 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.00617008 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00616939 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00616473 |
| TOX3 | TOX high mobility group box family member 3 | 0.00613947 |
| ACVR1 | activin A receptor, type I | 0.00607718 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00605568 |
| CCNB2 | cyclin B2 | 0.00602886 |
| PCDH9 | protocadherin 9 | 0.00597621 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00592631 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | 0.00591317 |
| CLU | clusterin | 0.00588389 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 0.00585905 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.0058489 |
| PLK1 | polo-like kinase 1 | 0.00584859 |
| BAD | BCL2-associated agonist of cell death | 0.00583235 |
| ATMIN | ATM interactor | 0.00583032 |
| CHN2 | chimerin 2 | 0.00582457 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00581888 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00579183 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 0.00578775 |
| GLDC | glycine dehydrogenase (decarboxylating) | 0.00577889 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | 0.00577435 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | 0.00575037 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.00573538 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.00572576 |
| FAM13A | family with sequence similarity 13, member A | 0.00572538 |
| EFHD2 | EF-hand domain family, member D2 | 0.00570097 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00567519 |
| MAP7 | microtubule-associated protein 7 | 0.00565748 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.0056529 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | 0.00564879 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | 0.00564219 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00563096 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.0056208 |
| ZNF217 | zinc finger protein 217 | 0.00561436 |
| MAOA | monoamine oxidase A | 0.00559511 |
| TSPAN13 | tetraspanin 13 | 0.00556816 |
| FASN | fatty acid synthase | 0.00555104 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | 0.00552656 |
| TRIM8 | tripartite motif containing 8 | 0.00551647 |
| MAGED1 | melanoma antigen family D1 | 0.00551402 |
| FBLN2 | fibulin 2 | 0.00551335 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | 0.0055073 |
| AOC3 | amine oxidase, copper containing 3 | 0.00548854 |
| GATA2 | GATA binding protein 2 | 0.00548539 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.00548097 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00547402 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00545849 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00545653 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.00545195 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00543697 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | 0.00543109 |
| PLXND1 | plexin D1 | 0.00540275 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.00538855 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | 0.00538542 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00536033 |
| CST3 | cystatin C | 0.0053469 |
| FADS1 | fatty acid desaturase 1 | 0.00532581 |
| HEBP2 | heme binding protein 2 | 0.0053018 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) | 0.00529184 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | 0.00527901 |
| VPS51 | vacuolar protein sorting 51 homolog (S. cerevisiae) | 0.00527718 |
| ARHGAP17 | Rho GTPase activating protein 17 | 0.00527022 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00524646 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | 0.00521917 |
| CFB | complement factor B | 0.00521032 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.00519815 |
| USP48 | ubiquitin specific peptidase 48 | 0.00519283 |
| GET1 | guided entry of tail-anchored proteins factor 1 | 0.00516386 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.00515097 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00514763 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00514324 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00514272 |
| ISYNA1 | inositol-3-phosphate synthase 1 | 0.00510263 |
| KRT19 | keratin 19, type I | 0.00508517 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00508213 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00506978 |
| TBC1D16 | TBC1 domain family, member 16 | 0.00506666 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 0.00504105 |
| SASH1 | SAM and SH3 domain containing 1 | 0.00503267 |
| PCP4 | Purkinje cell protein 4 | 0.00501865 |
| CHKB | choline kinase beta | 0.00501708 |
| NID2 | nidogen 2 (osteonidogen) | 0.00501202 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.00500901 |
| SOD3 | superoxide dismutase 3, extracellular | 0.00499691 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.00498688 |
| KMT5B | lysine methyltransferase 5B | 0.004979 |
| KIAA0930 | KIAA0930 | 0.00496849 |
| SORD | sorbitol dehydrogenase | 0.00495536 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00492521 |
| ANXA4 | annexin A4 | 0.00490957 |
| TES | testin LIM domain protein | 0.00490785 |
| ADCY9 | adenylate cyclase 9 | 0.00489285 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 | 0.00487636 |
| KRT18 | keratin 18, type I | 0.00485985 |
| NBEA | neurobeachin | 0.00485081 |
| TUBGCP3 | tubulin, gamma complex associated protein 3 | 0.00483403 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.00482741 |
| BCL2L1 | BCL2-like 1 | 0.00481674 |
| SAFB2 | scaffold attachment factor B2 | 0.004809 |
| PDGFC | platelet derived growth factor C | 0.0048021 |
| NEFH | neurofilament, heavy polypeptide | 0.00480107 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00479181 |
| PRKCZ | protein kinase C, zeta | 0.00478923 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.00478859 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | 0.00478773 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00477154 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | 0.00476862 |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) | 0.00476221 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.00476091 |
| LAMB1 | laminin, beta 1 | 0.00474311 |
| PDE10A | phosphodiesterase 10A | 0.00474046 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | 0.00472746 |
| G0S2 | G0/G1 switch 2 | 0.00471995 |
| ATP9A | ATPase, class II, type 9A | 0.00471069 |
| PKP4 | plakophilin 4 | 0.00470736 |
| NOVA1 | neuro-oncological ventral antigen 1 | 0.00470276 |
| MGP | matrix Gla protein | 0.00468288 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00466895 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.00466683 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.004659 |
| IFT122 | intraflagellar transport 122 | 0.00465895 |
| SEPHS1 | selenophosphate synthetase 1 | 0.00465367 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00464571 |
| PALLD | palladin, cytoskeletal associated protein | 0.00462696 |
| ITGA7 | integrin, alpha 7 | 0.00462422 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.00461772 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00460864 |
| INTS1 | integrator complex subunit 1 | 0.00460559 |
| ZNF532 | zinc finger protein 532 | 0.00460375 |
| HMGB1 | high mobility group box 1 | 0.00460357 |
| ITGA8 | integrin, alpha 8 | 0.00460326 |
| CHMP6 | charged multivesicular body protein 6 | 0.00460121 |
| NCK2 | NCK adaptor protein 2 | 0.00459941 |
| NOTCH2NL | notch 2 N-terminal like | 0.00457895 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00456654 |
| UNC119B | unc-119 homolog B (C. elegans) | 0.00454627 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00454366 |
| CENPB | centromere protein B, 80kDa | 0.00454362 |
| MZT2A | mitotic spindle organizing protein 2A | 0.00453655 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 | 0.00453182 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00453173 |
| CPNE1 | copine I | 0.00453163 |
| BRD4 | bromodomain containing 4 | 0.00452707 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00451187 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00450214 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.00450051 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00450038 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0044929 |
| SMAD7 | SMAD family member 7 | 0.00448788 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00448362 |
| EFHD1 | EF-hand domain family, member D1 | 0.0044824 |
| MKKS | McKusick-Kaufman syndrome | 0.00445189 |
| INTS6 | integrator complex subunit 6 | 0.0044515 |
| PYGB | phosphorylase, glycogen; brain | 0.00444886 |
| XYLT1 | xylosyltransferase I | 0.00444327 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00443781 |
| BCR | breakpoint cluster region | 0.00443484 |
| PENK | proenkephalin | 0.00442725 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0044256 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.00442418 |
| PTER | phosphotriesterase related | 0.00441818 |
| TRIM28 | tripartite motif containing 28 | 0.0044176 |
| RTN3 | reticulon 3 | 0.00439393 |
| NFIC | nuclear factor I/C (CCAAT-binding transcription factor) | 0.00439289 |
| CPM | carboxypeptidase M | 0.00438998 |
| SORBS3 | sorbin and SH3 domain containing 3 | 0.00438169 |
| HHEX | hematopoietically expressed homeobox | 0.00437256 |
| HIP1R | huntingtin interacting protein 1 related | 0.00436136 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00435972 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00435709 |
| NDUFV1 | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa | 0.00435171 |
| FGF13 | fibroblast growth factor 13 | 0.004345 |
| TRIOBP | TRIO and F-actin binding protein | 0.00434235 |
| INA | internexin neuronal intermediate filament protein, alpha | 0.00432777 |
| ZNF274 | zinc finger protein 274 | 0.00432375 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 0.00432279 |
| CEP57 | centrosomal protein 57kDa | 0.00431567 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 0.00431075 |
| STK3 | serine/threonine kinase 3 | 0.00431 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IFITM1 | interferon induced transmembrane protein 1 | -0.0136811 |
| RGCC | regulator of cell cycle | -0.0121863 |
| XIC | X chromosome inactivation center | -0.0121599 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0119053 |
| MYBPC1 | myosin binding protein C, slow type | -0.0116085 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0114238 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0108521 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0108182 |
| TTN | titin | -0.0105633 |
| KRT5 | keratin 5, type II | -0.0104059 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.010319 |
| TNNC1 | troponin C type 1 (slow) | -0.0102201 |
| CLEC2B | C-type lectin domain family 2, member B | -0.0101851 |
| TEX10 | testis expressed 10 | -0.0100365 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00992251 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00975259 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00962797 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00949364 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00947351 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | -0.00944573 |
| ADM | adrenomedullin | -0.0094259 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00940299 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00920657 |
| SIRT3 | sirtuin 3 | -0.00920005 |
| SLN | sarcolipin | -0.00916362 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00904156 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00886638 |
| MMP12 | matrix metallopeptidase 12 | -0.00871489 |
| IFI44L | interferon-induced protein 44-like | -0.0087104 |
| IFI44 | interferon-induced protein 44 | -0.00863334 |
| RTN2 | reticulon 2 | -0.00862418 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.0084986 |
| FABP7 | fatty acid binding protein 7, brain | -0.00823536 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00819624 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00811002 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00810604 |
| ABLIM1 | actin binding LIM protein 1 | -0.00804972 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00796856 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.00793783 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00787766 |
| CLEC5A | C-type lectin domain family 5, member A | -0.00785177 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00781182 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00759478 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00754049 |
| FOLR1 | folate receptor 1 (adult) | -0.00752495 |
| CA2 | carbonic anhydrase II | -0.00752469 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00751929 |
| MB | myoglobin | -0.00746744 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00743985 |
| CYTIP | cytohesin 1 interacting protein | -0.00730521 |
| EGR2 | early growth response 2 | -0.0072756 |
| CD69 | CD69 molecule | -0.00724986 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | -0.00723538 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0072246 |
| KLHL41 | kelch-like family member 41 | -0.007198 |
| RGS1 | regulator of G-protein signaling 1 | -0.00714763 |
| TPM3 | tropomyosin 3 | -0.00709784 |
| EGR3 | early growth response 3 | -0.00709549 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00708804 |
| POSTN | periostin, osteoblast specific factor | -0.0069885 |
| EMX2 | empty spiracles homeobox 2 | -0.00696702 |
| MPO | myeloperoxidase | -0.00696358 |
| PODXL | podocalyxin-like | -0.00691331 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00691298 |
| MYOT | myotilin | -0.00684863 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00683355 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00674885 |
| GPM6A | glycoprotein M6A | -0.00673975 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00672939 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00672629 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 | -0.00672473 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00671267 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00670956 |
| LAPTM5 | lysosomal protein transmembrane 5 | -0.00670605 |
| SET | SET nuclear proto-oncogene | -0.00669522 |
| CALCRL | calcitonin receptor-like | -0.00668927 |
| ENO3 | enolase 3 (beta, muscle) | -0.00663012 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | -0.00661923 |
| S100A10 | S100 calcium binding protein A10 | -0.00659457 |
| TPM4 | tropomyosin 4 | -0.00658413 |
| BAALC | brain and acute leukemia, cytoplasmic | -0.00652165 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00649048 |
| GTPBP8 | GTP-binding protein 8 (putative) | -0.0064567 |
| CST1 | cystatin SN | -0.00642858 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00642564 |
| IL1RN | interleukin 1 receptor antagonist | -0.0064194 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0064152 |
| S100A2 | S100 calcium binding protein A2 | -0.00639485 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00637774 |
| MXI1 | MAX interactor 1, dimerization protein | -0.00637716 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00636801 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00635966 |
| S100A7 | S100 calcium binding protein A7 | -0.00635089 |
| MYOZ2 | myozenin 2 | -0.00635078 |
| THBS1 | thrombospondin 1 | -0.00634773 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.00633924 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -0.00633524 |
| HLA-B | major histocompatibility complex, class I, B | -0.00630839 |
| GPR183 | G protein-coupled receptor 183 | -0.00630774 |
| GPM6B | glycoprotein M6B | -0.00630505 |
| NCF2 | neutrophil cytosolic factor 2 | -0.00630094 |
| MUC16 | mucin 16, cell surface associated | -0.00629989 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.00626779 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.0062569 |
| TNNC2 | troponin C type 2 (fast) | -0.00623477 |
| CALML5 | calmodulin-like 5 | -0.0062334 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00613917 |
| GOLM1 | golgi membrane protein 1 | -0.00613391 |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | -0.00613168 |
| PRTN3 | proteinase 3 | -0.00612363 |
| SRGN | serglycin | -0.00608993 |
| CKM | creatine kinase, muscle | -0.00601567 |
| PLEK | pleckstrin | -0.00601171 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 | -0.00601144 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00600604 |
| MSX1 | msh homeobox 1 | -0.00599782 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00599113 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | -0.00598166 |
| GRAMD2B | GRAM domain containing 2B | -0.00594067 |
| AQP4 | aquaporin 4 | -0.00592876 |
| CANX | calnexin | -0.0059202 |
| SMPX | small muscle protein, X-linked | -0.00584729 |
| BMP7 | bone morphogenetic protein 7 | -0.00583707 |
| CST7 | cystatin F (leukocystatin) | -0.00582385 |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) | -0.00581368 |
| ZNF395 | zinc finger protein 395 | -0.00581112 |
| CA3 | carbonic anhydrase III | -0.00580527 |
| CLDND1 | claudin domain containing 1 | -0.00579045 |
| FOSL2 | FOS-like antigen 2 | -0.00578464 |
| ACTN1 | actinin, alpha 1 | -0.00576094 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00574955 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.00574355 |
| DSP | desmoplakin | -0.00567627 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00564958 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00564524 |
| EMP1 | epithelial membrane protein 1 | -0.00563432 |
| CD83 | CD83 molecule | -0.00562395 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.00561703 |
| ATP10B | ATPase, class V, type 10B | -0.00559845 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.00559459 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00558218 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00557526 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00555298 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00553886 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.00553213 |
| ETNPPL | ethanolamine-phosphate phospho-lyase | -0.00551968 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.00550795 |
| PALMD | palmdelphin | -0.00549525 |
| INHBB | inhibin, beta B | -0.00549181 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00548848 |
| EVI2A | ecotropic viral integration site 2A | -0.00542041 |
| MYBPC2 | myosin binding protein C, fast type | -0.00541089 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00539971 |
| POPDC3 | popeye domain containing 3 | -0.00539918 |
| GLO1 | glyoxalase I | -0.00539649 |
| LINC00623 | long intergenic non-protein coding RNA 623 | -0.00538987 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | -0.00536189 |
| SOX17 | SRY (sex determining region Y)-box 17 | -0.00535119 |
| RASGRP3 | RAS guanyl releasing protein 3 (calcium and DAG-regulated) | -0.00534505 |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase | -0.00531906 |
| TNNI1 | troponin I type 1 (skeletal, slow) | -0.00528976 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00525809 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.00525551 |
| FBXO11 | F-box protein 11 | -0.00524729 |
| PLIN2 | perilipin 2 | -0.00524615 |
| ANXA3 | annexin A3 | -0.00523574 |
| DAZAP2 | DAZ associated protein 2 | -0.00523326 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00523113 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00519878 |
| BMP4 | bone morphogenetic protein 4 | -0.00519514 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00519054 |
| PLP1 | proteolipid protein 1 | -0.00518498 |
| LY96 | lymphocyte antigen 96 | -0.00518059 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.00518009 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00517893 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00517844 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.00517486 |
| KLF6 | Kruppel-like factor 6 | -0.00516121 |
| ARG1 | arginase 1 | -0.00515206 |
| MCL1 | myeloid cell leukemia 1 | -0.00514851 |
| RANBP9 | RAN binding protein 9 | -0.00514346 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00513208 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | -0.0051307 |
| NPR3 | natriuretic peptide receptor 3 | -0.00511983 |
| KRT6A | keratin 6A, type II | -0.00511605 |
| ITGA6 | integrin, alpha 6 | -0.00511527 |
| ELANE | elastase, neutrophil expressed | -0.00509736 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.00507356 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | -0.00506678 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00505732 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00504673 |
| EDN3 | endothelin 3 | -0.00504129 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00502104 |
| CNN2 | calponin 2 | -0.00501661 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -0.00501561 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00501371 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00499169 |
| HLA-F | major histocompatibility complex, class I, F | -0.00498992 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.00498706 |
| TYRP1 | tyrosinase-related protein 1 | -0.00498142 |
| PRKCQ | protein kinase C, theta | -0.00498102 |
| MMP10 | matrix metallopeptidase 10 | -0.00497734 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00496907 |
| HCP5 | HLA complex P5 (non-protein coding) | -0.004957 |
| TSPAN8 | tetraspanin 8 | -0.0049496 |
| FAM198B | family with sequence similarity 198, member B | -0.00493625 |
| B2M | beta-2-microglobulin | -0.0049302 |
| EDNRB | endothelin receptor type B | -0.00491897 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -0.00491105 |
| KLHDC8A | kelch domain containing 8A | -0.00489672 |
| ATF3 | activating transcription factor 3 | -0.00489617 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) | -0.00489008 |
| GOLT1B | golgi transport 1B | -0.00488948 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00488763 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -0.00487324 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00486948 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | -0.00486642 |
| CAPRIN1 | cell cycle associated protein 1 | -0.00485493 |
| THBS2 | thrombospondin 2 | -0.00485116 |
| WLS | wntless Wnt ligand secretion mediator | -0.00484667 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00484233 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 | -0.00483819 |
| CD200 | CD200 molecule | -0.00483405 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00483312 |
| EXOC5 | exocyst complex component 5 | -0.00481213 |
| NDP | Norrie disease (pseudoglioma) | -0.00480919 |
| PDZD2 | PDZ domain containing 2 | -0.00480915 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00480901 |
| GUCY2C | guanylate cyclase 2C | -0.00479314 |
| FCGBP | Fc fragment of IgG binding protein | -0.00479096 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 | -0.00479084 |
| ADORA2B | adenosine A2b receptor | -0.00478326 |
| COL10A1 | collagen, type X, alpha 1 | -0.00478138 |
| TARP | TCR gamma alternate reading frame protein | -0.00475922 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00474529 |
| MEX3D | mex-3 RNA binding family member D | -0.00474485 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.00473891 |
| REEP5 | receptor accessory protein 5 | -0.00472687 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00472378 |
| PRAME | preferentially expressed antigen in melanoma | -0.00472282 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00470373 |
| STAT5B | signal transducer and activator of transcription 5B | -0.00469871 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.00468261 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.00468144 |
| RAPGEF4 | Rap guanine nucleotide exchange factor (GEF) 4 | -0.00466757 |
| RGS4 | regulator of G-protein signaling 4 | -0.00466741 |
| STXBP6 | syntaxin binding protein 6 (amisyn) | -0.00466666 |
| USP18 | ubiquitin specific peptidase 18 | -0.00464701 |
| LTF | lactotransferrin | -0.00463669 |
