HLF Gene Set

Dataset JASPAR Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description hepatic leukemia factor|This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3131)
External Link http://www.ncbi.nlm.nih.gov/gene/3131
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Genes

53 target genes of the HLF transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.

Symbol Name
ATP6V1G2-DDX39B ATP6V1G2-DDX39B readthrough (NMD candidate)
BRD2 bromodomain containing 2
C12ORF65 chromosome 12 open reading frame 65
CDX2 caudal type homeobox 2
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EYA1 EYA transcriptional coactivator and phosphatase 1
FAM101B family with sequence similarity 101, member B
FAM21A family with sequence similarity 21, member A
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FLOT1 flotillin 1
FRS3 fibroblast growth factor receptor substrate 3
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GNL1 guanine nucleotide binding protein-like 1
GPHRB golgi pH regulator B
GTPBP6 GTP binding protein 6 (putative)
HCG26 HLA complex group 26 (non-protein coding)
HCP5 HLA complex P5 (non-protein coding)
HLA-E major histocompatibility complex, class I, E
HOXD9 homeobox D9
LINC00518 long intergenic non-protein coding RNA 518
LINC00685 long intergenic non-protein coding RNA 685
LIPI lipase, member I
LOC388942 uncharacterized LOC388942
LOC401242 uncharacterized LOC401242
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MILR1 mast cell immunoglobulin-like receptor 1
MIR30B microRNA 30b
MIR3648-1 microRNA 3648-1
MIR3687-1 microRNA 3687-1
NBPF14 neuroblastoma breakpoint family, member 14
NEU1 sialidase 1 (lysosomal sialidase)
OR5T3 olfactory receptor, family 5, subfamily T, member 3
PARP4 poly (ADP-ribose) polymerase family, member 4
PRRC2A proline-rich coiled-coil 2A
RARB retinoic acid receptor, beta
REXO1L1P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene
REXO1L2P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 2, pseudogene
RNF38 ring finger protein 38
RNF39 ring finger protein 39
SLC25A26 solute carrier family 25 (S-adenosylmethionine carrier), member 26
SSBP2 single-stranded DNA binding protein 2
TCF19 transcription factor 19
TNF tumor necrosis factor
TNXB tenascin XB
TRIM26 tripartite motif containing 26
TRIM40 tripartite motif containing 40
VARS valyl-tRNA synthetase
ZDHHC16 zinc finger, DHHC-type containing 16
ZFP57 ZFP57 zinc finger protein
ZNF641 zinc finger protein 641