| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | heme oxygenase 1|Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3162) |
| External Link | https://ncbi.nlm.nih.gov/gene/3162 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the HMOX1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 0.0073775 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00615452 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00615002 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00606922 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.005841 |
| CEP57 | centrosomal protein 57kDa | 0.0058142 |
| CCNB1 | cyclin B1 | 0.0057393 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | 0.00561569 |
| THBS4 | thrombospondin 4 | 0.00540664 |
| TMSB15A | thymosin beta 15a | 0.00530351 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0052175 |
| LTF | lactotransferrin | 0.00519454 |
| PROM1 | prominin 1 | 0.00519069 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00499268 |
| FHL1 | four and a half LIM domains 1 | 0.00498476 |
| HMGN4 | high mobility group nucleosomal binding domain 4 | 0.00497771 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00495604 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00489262 |
| THYN1 | thymocyte nuclear protein 1 | 0.00483525 |
| CD52 | CD52 molecule | 0.00478228 |
| TRIM2 | tripartite motif containing 2 | 0.00473647 |
| GNAS | GNAS complex locus | 0.00472961 |
| COL6A3 | collagen, type VI, alpha 3 | 0.00469385 |
| ACD | adrenocortical dysplasia homolog (mouse) | 0.00469215 |
| DES | desmin | 0.00465038 |
| CLDN3 | claudin 3 | 0.0046438 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00463612 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00461078 |
| KIF20A | kinesin family member 20A | 0.0045663 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00454754 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00454662 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00452569 |
| C7 | complement component 7 | 0.00451144 |
| PRKCA | protein kinase C, alpha | 0.00450673 |
| SIRT3 | sirtuin 3 | 0.00441828 |
| ITM2A | integral membrane protein 2A | 0.00441361 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00440198 |
| OLFM4 | olfactomedin 4 | 0.00436958 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00435544 |
| NELL2 | NEL-like 2 (chicken) | 0.00435266 |
| TUBA1A | tubulin, alpha 1a | 0.00434163 |
| ELN | elastin | 0.00433467 |
| SLC25A46 | solute carrier family 25, member 46 | 0.00432835 |
| CRYM | crystallin, mu | 0.00430508 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00429958 |
| NAE1 | NEDD8 activating enzyme E1 subunit 1 | 0.00428658 |
| PDLIM3 | PDZ and LIM domain 3 | 0.00427143 |
| TFRC | transferrin receptor | 0.00426618 |
| THAP11 | THAP domain containing 11 | 0.00424302 |
| KIF14 | kinesin family member 14 | 0.00423102 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.00417969 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00409331 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00408703 |
| FCGBP | Fc fragment of IgG binding protein | 0.00408633 |
| RGS10 | regulator of G-protein signaling 10 | 0.00407663 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 0.00407368 |
| CEP68 | centrosomal protein 68kDa | 0.00407091 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00406826 |
| DPT | dermatopontin | 0.00406752 |
| GPR183 | G protein-coupled receptor 183 | 0.00405227 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 0.00404109 |
| FAM169A | family with sequence similarity 169, member A | 0.00397604 |
| TYRP1 | tyrosinase-related protein 1 | 0.00396377 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.00390542 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00389765 |
| CHKB | choline kinase beta | 0.0038853 |
| TMEM38B | transmembrane protein 38B | 0.00387398 |
| PTCH1 | patched 1 | 0.0038704 |
| SPA17 | sperm autoantigenic protein 17 | 0.00386733 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.00386026 |
| H2AX | H2A.X variant histone | 0.00384224 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.00382623 |
| NEK2 | NIMA-related kinase 2 | 0.00382208 |
| H1-10 | H1.10 linker histone | 0.00381165 |
| HMG20B | high mobility group 20B | 0.00380807 |
| OXCT1 | 3-oxoacid CoA transferase 1 | 0.00380518 |
| ABHD11 | abhydrolase domain containing 11 | 0.00379632 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.00378414 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) | 0.0037823 |
| ESD | esterase D | 0.00375663 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00373031 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.00371316 |
| PALLD | palladin, cytoskeletal associated protein | 0.00371113 |
| NUCB1 | nucleobindin 1 | 0.00370713 |
| CUX2 | cut-like homeobox 2 | 0.0037068 |
| ADORA2B | adenosine A2b receptor | 0.00369838 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00367356 |
| PRMT1 | protein arginine methyltransferase 1 | 0.00367238 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.00365615 |
| KIF23 | kinesin family member 23 | 0.003656 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00364193 |
| PTOV1 | prostate tumor overexpressed 1 | 0.00361872 |
| EIF4E | eukaryotic translation initiation factor 4E | 0.00361299 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | 0.00360882 |
| FNBP1 | formin binding protein 1 | 0.00359852 |
| KPNA3 | karyopherin alpha 3 (importin alpha 4) | 0.00357921 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00356434 |
| KLHL23 | kelch-like family member 23 | 0.00356133 |
| ZNF274 | zinc finger protein 274 | 0.00354078 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00352027 |
| COL1A2 | collagen, type I, alpha 2 | 0.00351205 |
| ANKRD49 | ankyrin repeat domain 49 | 0.00351201 |
| GATA2 | GATA binding protein 2 | 0.00349564 |
| FLNA | filamin A, alpha | 0.00348509 |
| NKX2-2 | NK2 homeobox 2 | 0.00348409 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.0034804 |
| LEPR | leptin receptor | 0.00347722 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.00347258 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00347169 |
| GOLM1 | golgi membrane protein 1 | 0.00346562 |
| PFN1 | profilin 1 | 0.00346294 |
| TRAPPC13 | trafficking protein particle complex 13 | 0.00345305 |
| PHYH | phytanoyl-CoA 2-hydroxylase | 0.00344883 |
| FILIP1L | filamin A interacting protein 1-like | 0.00344504 |
| MOCS2 | molybdenum cofactor synthesis 2 | 0.00344417 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.0034434 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | 0.00343603 |
| HMGB2 | high mobility group box 2 | 0.00342748 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.00342159 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0034204 |
| CNN1 | calponin 1, basic, smooth muscle | 0.00341781 |
| STK10 | serine/threonine kinase 10 | 0.00341531 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.00340213 |
| NXN | nucleoredoxin | 0.00340194 |
| TGFB1 | transforming growth factor, beta 1 | 0.00339769 |
| S100A10 | S100 calcium binding protein A10 | 0.0033956 |
| GPM6A | glycoprotein M6A | 0.00337787 |
| CKAP2 | cytoskeleton associated protein 2 | 0.00337564 |
| AUTS2 | autism susceptibility candidate 2 | 0.00336852 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | 0.0033658 |
| HIP1 | huntingtin interacting protein 1 | 0.0033643 |
| INSIG1 | insulin induced gene 1 | 0.00335823 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | 0.00334607 |
| HYOU1 | hypoxia up-regulated 1 | 0.00334404 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00334402 |
| NEBL | nebulette | 0.00333551 |
| REEP1 | receptor accessory protein 1 | 0.00333279 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.00332712 |
| OTULINL | OTU deubiquitinase with linear linkage specificity like | 0.00332076 |
| RPIA | ribose 5-phosphate isomerase A | 0.00331977 |
| ESRP2 | epithelial splicing regulatory protein 2 | 0.0033006 |
| SHCBP1 | SHC SH2-domain binding protein 1 | 0.00329707 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.00327971 |
| TRIM28 | tripartite motif containing 28 | 0.00326771 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein | 0.00326342 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.00325749 |
| NKX3-1 | NK3 homeobox 1 | 0.00325275 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00325102 |
| MLF1 | myeloid leukemia factor 1 | 0.00324749 |
| TAGLN2 | transgelin 2 | 0.00324224 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.00322443 |
| ABHD2 | abhydrolase domain containing 2 | 0.00322298 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00320505 |
| SC5D | sterol-C5-desaturase | 0.00320464 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.00320318 |
| ABHD10 | abhydrolase domain containing 10 | 0.00319414 |
| SEPTIN9 | septin 9 | 0.0031908 |
| NSL1 | NSL1, MIS12 kinetochore complex component | 0.0031891 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0031883 |
| BAX | BCL2-associated X protein | 0.00318824 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 0.00318292 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.00318047 |
| THAP12 | THAP domain containing 12 | 0.00317486 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00317102 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00316991 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00316961 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.0031691 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00316423 |
| PFKL | phosphofructokinase, liver | 0.00315904 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.00315477 |
| WLS | wntless Wnt ligand secretion mediator | 0.00314544 |
| GNAL | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type | 0.00314319 |
| ANXA3 | annexin A3 | 0.00314223 |
| CBFB | core-binding factor, beta subunit | 0.0031381 |
| H2AFV | H2A histone family, member V | 0.00313637 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00313556 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00313112 |
| LYZ | lysozyme | 0.00312958 |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | 0.00312955 |
| ZNF204P | zinc finger protein 204, pseudogene | 0.00312876 |
| SETMAR | SET domain and mariner transposase fusion gene | 0.00312714 |
| TRAPPC4 | trafficking protein particle complex 4 | 0.00312169 |
| SORBS3 | sorbin and SH3 domain containing 3 | 0.00311559 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00310831 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | 0.00310026 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00310009 |
| LBR | lamin B receptor | 0.00308192 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 0.00307155 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.00306507 |
| NOX1 | NADPH oxidase 1 | 0.00306335 |
| TSPAN4 | tetraspanin 4 | 0.0030528 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00305245 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.00305137 |
| ECT2 | epithelial cell transforming 2 | 0.00304991 |
| PRELID3B | PRELI domain containing 3B | 0.00304259 |
| ZNF468 | zinc finger protein 468 | 0.0030327 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0030143 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00299885 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | 0.00299349 |
| CIAO2B | cytosolic iron-sulfur assembly component 2B | 0.00297898 |
| FERMT1 | fermitin family member 1 | 0.00297884 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) | 0.00297785 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.00297747 |
| MSMB | microseminoprotein, beta- | 0.00297492 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 0.00296145 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 | 0.00295671 |
| IL7R | interleukin 7 receptor | 0.00295628 |
| DCK | deoxycytidine kinase | 0.00293647 |
| WWC2 | WW and C2 domain containing 2 | 0.00293286 |
| NANS | N-acetylneuraminic acid synthase | 0.00293004 |
| C9ORF40 | chromosome 9 open reading frame 40 | 0.00292996 |
| NOSIP | nitric oxide synthase interacting protein | 0.00292686 |
| LY6H | lymphocyte antigen 6 complex, locus H | 0.00292606 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00291788 |
| SNRPA | small nuclear ribonucleoprotein polypeptide A | 0.00291578 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 0.00290715 |
| CDC25C | cell division cycle 25C | 0.002904 |
| CENPF | centromere protein F, 350/400kDa | 0.00290284 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.00289689 |
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.00289573 |
| ACTC1 | actin, alpha, cardiac muscle 1 | 0.0028925 |
| ADRA2A | adrenoceptor alpha 2A | 0.00289113 |
| SRSF6 | serine/arginine-rich splicing factor 6 | 0.00289062 |
| SALL2 | spalt-like transcription factor 2 | 0.00288264 |
| FBXO11 | F-box protein 11 | 0.00287349 |
| HMGA1 | high mobility group AT-hook 1 | 0.00287018 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | 0.00286724 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.00286352 |
| FA2H | fatty acid 2-hydroxylase | 0.00285759 |
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | 0.00285579 |
| REG3A | regenerating islet-derived 3 alpha | 0.00285488 |
| ELOVL4 | ELOVL fatty acid elongase 4 | 0.0028527 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | 0.00284733 |
| GPA33 | glycoprotein A33 (transmembrane) | 0.00284272 |
| NKX2-1 | NK2 homeobox 1 | 0.00284267 |
| SVIL | supervillin | 0.00283906 |
| CCNB2 | cyclin B2 | 0.00282651 |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | 0.0028259 |
| FBLN5 | fibulin 5 | 0.00282585 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00282376 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00281949 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00281882 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00281704 |
| CMC2 | C-x(9)-C motif containing 2 | 0.00281391 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.0028094 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | 0.00280732 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00280483 |
| ZDHHC7 | zinc finger, DHHC-type containing 7 | 0.0028012 |
| SHTN1 | shootin 1 | 0.00280003 |
| FABP1 | fatty acid binding protein 1, liver | 0.00279509 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HMOX1 | heme oxygenase 1 | -0.0104008 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00953314 |
| MT1E | metallothionein 1E | -0.00925922 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.00852986 |
| MT1X | metallothionein 1X | -0.00844411 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0078534 |
| CLU | clusterin | -0.00778824 |
| MT1G | metallothionein 1G | -0.00775679 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00721547 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0070241 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00700104 |
| HSPA2 | heat shock 70kDa protein 2 | -0.0069234 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0067152 |
| MT1H | metallothionein 1H | -0.00670374 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00669208 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.0066729 |
| KRT17 | keratin 17, type I | -0.00666024 |
| GLUL | glutamate-ammonia ligase | -0.00652503 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00649918 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00643294 |
| IL1RN | interleukin 1 receptor antagonist | -0.00638033 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00629861 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00627107 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00624434 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00615759 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00615539 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00614884 |
| S100A9 | S100 calcium binding protein A9 | -0.00602599 |
| MT1F | metallothionein 1F | -0.00600848 |
| CRYAB | crystallin, alpha B | -0.00596599 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0059577 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.005869 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00581501 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00579864 |
| KRT6A | keratin 6A, type II | -0.005745 |
| KRT14 | keratin 14, type I | -0.00567609 |
| CA2 | carbonic anhydrase II | -0.00564905 |
| PLTP | phospholipid transfer protein | -0.00562414 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00562377 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00557773 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00554595 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.00553414 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00551652 |
| SFN | stratifin | -0.00549947 |
| CA12 | carbonic anhydrase XII | -0.00546773 |
| CCDC92 | coiled-coil domain containing 92 | -0.00539162 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00539148 |
| AZU1 | azurocidin 1 | -0.00538102 |
| AIM2 | absent in melanoma 2 | -0.00530641 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.00528313 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00526349 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00523286 |
| CSTA | cystatin A (stefin A) | -0.00519896 |
| NRCAM | neuronal cell adhesion molecule | -0.00517921 |
| ADM | adrenomedullin | -0.00517882 |
| CYBB | cytochrome b-245, beta polypeptide | -0.00517064 |
| KAZN | kazrin, periplakin interacting protein | -0.00516863 |
| IFI44L | interferon-induced protein 44-like | -0.00514831 |
| KRT23 | keratin 23, type I | -0.00511922 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.00511686 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00511355 |
| CCN3 | cellular communication network factor 3 | -0.00509119 |
| KRT6B | keratin 6B, type II | -0.00507414 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00506884 |
| S100A8 | S100 calcium binding protein A8 | -0.005028 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.005024 |
| CD163 | CD163 molecule | -0.00501824 |
| DEFB1 | defensin, beta 1 | -0.00499162 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | -0.00498913 |
| TMEM45A | transmembrane protein 45A | -0.00497118 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00495949 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -0.00495651 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00495548 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00494139 |
| HAL | histidine ammonia-lyase | -0.00493888 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00491879 |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) | -0.00489966 |
| ABHD4 | abhydrolase domain containing 4 | -0.00487901 |
| TMEM164 | transmembrane protein 164 | -0.00487001 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.00486649 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00486197 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00482217 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00481585 |
| KRT16 | keratin 16, type I | -0.00475335 |
| TMEM140 | transmembrane protein 140 | -0.00474628 |
| ADIRF | adipogenesis regulatory factor | -0.00473345 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00471688 |
| YBX3 | Y box binding protein 3 | -0.00468941 |
| KLK10 | kallikrein-related peptidase 10 | -0.00468842 |
| HOMER3 | homer scaffolding protein 3 | -0.00466336 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00464393 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.00461306 |
| LYST | lysosomal trafficking regulator | -0.00459967 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00458813 |
| SNAI2 | snail family zinc finger 2 | -0.00458186 |
| GLA | galactosidase, alpha | -0.00457958 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00457255 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.00456803 |
| NEFM | neurofilament, medium polypeptide | -0.00456423 |
| TBX2 | T-box 2 | -0.00454323 |
| CALCA | calcitonin-related polypeptide alpha | -0.00442814 |
| JUP | junction plakoglobin | -0.00442496 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00440996 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00440114 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.00439239 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00439146 |
| KLHL9 | kelch-like family member 9 | -0.00437261 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | -0.00435449 |
| NOTCH2NL | notch 2 N-terminal like | -0.00433456 |
| TGM1 | transglutaminase 1 | -0.00431895 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.0043061 |
| MFSD1 | major facilitator superfamily domain containing 1 | -0.00430046 |
| KLHL21 | kelch-like family member 21 | -0.00428197 |
| CTSA | cathepsin A | -0.00427958 |
| S100A2 | S100 calcium binding protein A2 | -0.00427315 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -0.00427131 |
| MX2 | MX dynamin-like GTPase 2 | -0.0042269 |
| GAB2 | GRB2-associated binding protein 2 | -0.00422273 |
| BCL2L2 | BCL2-like 2 | -0.00420186 |
| DUSP5 | dual specificity phosphatase 5 | -0.0041689 |
| SPRR2B | small proline-rich protein 2B | -0.00416385 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00415798 |
| ASPH | aspartate beta-hydroxylase | -0.00414899 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.00414264 |
| MT2A | metallothionein 2A | -0.00410938 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00407284 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00405446 |
| PDGFD | platelet derived growth factor D | -0.00404588 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00404403 |
| TLR2 | toll-like receptor 2 | -0.00403367 |
| RND3 | Rho family GTPase 3 | -0.00401656 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.0039875 |
| SCPEP1 | serine carboxypeptidase 1 | -0.00394927 |
| EHD3 | EH-domain containing 3 | -0.0039436 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00393285 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00392802 |
| LIMK2 | LIM domain kinase 2 | -0.00390455 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -0.00388886 |
| THBD | thrombomodulin | -0.00387851 |
| PLXND1 | plexin D1 | -0.00387697 |
| RRAGD | Ras-related GTP binding D | -0.00387681 |
| COMT | catechol-O-methyltransferase | -0.00387452 |
| ELANE | elastase, neutrophil expressed | -0.00387099 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00387085 |
| PLSCR4 | phospholipid scramblase 4 | -0.00386148 |
| PLXNC1 | plexin C1 | -0.00385761 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00385058 |
| SIRPA | signal-regulatory protein alpha | -0.00385009 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | -0.00384893 |
| TBXA2R | thromboxane A2 receptor | -0.0038001 |
| MAGEA3 | melanoma antigen family A3 | -0.00379015 |
| APOL1 | apolipoprotein L, 1 | -0.00378756 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.00377882 |
| CFD | complement factor D (adipsin) | -0.00377651 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0037723 |
| AHNAK | AHNAK nucleoprotein | -0.00376128 |
| GPR137B | G protein-coupled receptor 137B | -0.00374757 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00373619 |
| IGF1R | insulin-like growth factor 1 receptor | -0.00373341 |
| CD93 | CD93 molecule | -0.00371442 |
| MT1M | metallothionein 1M | -0.00371155 |
| PLAT | plasminogen activator, tissue | -0.00371136 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00370642 |
| CLTB | clathrin, light chain B | -0.00370331 |
| EBLN2 | endogenous Bornavirus-like nucleoprotein 2 | -0.00369704 |
| PLS3 | plastin 3 | -0.00366528 |
| MUC1 | mucin 1, cell surface associated | -0.00366109 |
| MFAP3L | microfibrillar-associated protein 3-like | -0.00363591 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.00362827 |
| STX3 | syntaxin 3 | -0.00362575 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.00362091 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00361615 |
| GOLT1B | golgi transport 1B | -0.00361576 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.00360501 |
| SUSD6 | sushi domain containing 6 | -0.00360166 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00358947 |
| ZBED2 | zinc finger, BED-type containing 2 | -0.00358851 |
| PRTN3 | proteinase 3 | -0.00358075 |
| OPN3 | opsin 3 | -0.00357999 |
| ZNF512B | zinc finger protein 512B | -0.00357041 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00356879 |
| FOSL2 | FOS-like antigen 2 | -0.00355399 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00355288 |
| HPSE | heparanase | -0.00353928 |
| CNN3 | calponin 3, acidic | -0.00352549 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.00352195 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00350291 |
| WT1 | Wilms tumor 1 | -0.00350279 |
| HOXC6 | homeobox C6 | -0.00349904 |
| PITX3 | paired-like homeodomain 3 | -0.00349421 |
| CSNK1E | casein kinase 1, epsilon | -0.00348977 |
| IRAG2 | inositol 1,4,5-triphosphate receptor associated 2 | -0.00348534 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00348489 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00348095 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00347889 |
| RALB | v-ral simian leukemia viral oncogene homolog B | -0.00347639 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00347588 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G | -0.00347153 |
| TUBB6 | tubulin, beta 6 class V | -0.0034658 |
| BCL2L13 | BCL2-like 13 (apoptosis facilitator) | -0.00346515 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.00345652 |
| BCL2A1 | BCL2-related protein A1 | -0.00345266 |
| FPR1 | formyl peptide receptor 1 | -0.00345158 |
| EIF5 | eukaryotic translation initiation factor 5 | -0.00343694 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.00343672 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -0.00343374 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.0034304 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.00342916 |
| C1ORF54 | chromosome 1 open reading frame 54 | -0.00342885 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.00342762 |
| TRAM1 | translocation associated membrane protein 1 | -0.00342113 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.00341865 |
| TSPO | translocator protein (18kDa) | -0.00341814 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0034181 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.00341806 |
| IRS2 | insulin receptor substrate 2 | -0.00341191 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00340959 |
| EGR3 | early growth response 3 | -0.00340325 |
| EXOSC4 | exosome component 4 | -0.00340049 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00339935 |
| LOX | lysyl oxidase | -0.00339596 |
| TM2D1 | TM2 domain containing 1 | -0.00338371 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0033835 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.0033688 |
| PLEK | pleckstrin | -0.00336601 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | -0.0033659 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.00336503 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00335779 |
| KLK7 | kallikrein-related peptidase 7 | -0.00335693 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00335662 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | -0.00335003 |
| TGM3 | transglutaminase 3 | -0.00334609 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00334209 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00334117 |
| DSG3 | desmoglein 3 | -0.00334044 |
| PRDX4 | peroxiredoxin 4 | -0.00333908 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | -0.00333878 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | -0.00333868 |
| CADM1 | cell adhesion molecule 1 | -0.00333679 |
| FADS3 | fatty acid desaturase 3 | -0.00333089 |
| LIF | leukemia inhibitory factor | -0.00332892 |
| STC2 | stanniocalcin 2 | -0.00331459 |
| HOXB2 | homeobox B2 | -0.00330509 |
| PPL | periplakin | -0.00330233 |
| SIK1 | salt-inducible kinase 1 | -0.00330029 |
| FGF1 | fibroblast growth factor 1 (acidic) | -0.0032998 |
| RRAGC | Ras-related GTP binding C | -0.00329713 |
| XAF1 | XIAP associated factor 1 | -0.00329536 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -0.00328818 |
