HNF1 Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description HNF1 homeobox A|The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015] (NCBI Entrez Gene Database, 6927)
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Genes

53 target genes of the HNF1 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
AFM afamin
AHNAK AHNAK nucleoprotein
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
AMOTL2 angiomotin like 2
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPTL3 angiopoietin-like 3
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
ATG2A autophagy related 2A
ATP11B ATPase, class VI, type 11B
CDA cytidine deaminase
CDC42SE2 CDC42 small effector 2
CDHR2 cadherin-related family member 2
CLCN5 chloride channel, voltage-sensitive 5
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
EGR1 early growth response 1
FAM162A family with sequence similarity 162, member A
G6PC glucose-6-phosphatase, catalytic subunit
GJB1 gap junction protein, beta 1, 32kDa
GLTPD2 glycolipid transfer protein domain containing 2
GPR39 G protein-coupled receptor 39
HGFAC HGF activator
HNF1A HNF1 homeobox A
HNF4G hepatocyte nuclear factor 4, gamma
HOXA11 homeobox A11
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIF16B kinesin family member 16B
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LIPC lipase, hepatic
LLGL2 lethal giant larvae homolog 2 (Drosophila)
MAML2 mastermind-like 2 (Drosophila)
MIA2 melanoma inhibitory activity 2
MIR629 microRNA 629
MSH5-SAPCD1 MSH5-SAPCD1 readthrough (NMD candidate)
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NR0B2 nuclear receptor subfamily 0, group B, member 2
NRK Nik related kinase
RNASE4 ribonuclease, RNase A family, 4
RNF186 ring finger protein 186
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SFTA2 surfactant associated 2
SGK2 serum/glucocorticoid regulated kinase 2
SH3RF1 SH3 domain containing ring finger 1
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC38A4 solute carrier family 38, member 4
SLC4A2 solute carrier family 4 (anion exchanger), member 2
STXBP6 syntaxin binding protein 6 (amisyn)
TLE4 transducin-like enhancer of split 4
USP53 ubiquitin specific peptidase 53
VSIG1 V-set and immunoglobulin domain containing 1
VWA5B2 von Willebrand factor A domain containing 5B2
ZBTB38 zinc finger and BTB domain containing 38
ZIC2 Zic family member 2