| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | HNF1 homeobox B|This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 6928) |
| External Link | https://ncbi.nlm.nih.gov/gene/6928 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the HNF1B gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BMP4 | bone morphogenetic protein 4 | 0.0206456 |
| S100A7 | S100 calcium binding protein A7 | 0.0176527 |
| XPO7 | exportin 7 | 0.0163161 |
| KLK10 | kallikrein-related peptidase 10 | 0.0153345 |
| HIST1H2AC | histone cluster 1, H2ac | 0.0143307 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0142999 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0138303 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0137376 |
| KRT14 | keratin 14, type I | 0.0136062 |
| WDR7 | WD repeat domain 7 | 0.013414 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0133717 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0130278 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0128754 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.012636 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.0126037 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.0125598 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0120833 |
| S100A8 | S100 calcium binding protein A8 | 0.0120766 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0119767 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.0119235 |
| MT1E | metallothionein 1E | 0.0117815 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0116578 |
| LTF | lactotransferrin | 0.0114276 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.0114198 |
| S100A9 | S100 calcium binding protein A9 | 0.0114046 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.0110865 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.0110426 |
| IL1RN | interleukin 1 receptor antagonist | 0.0109549 |
| CCN2 | cellular communication network factor 2 | 0.0109536 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.0109347 |
| KLK11 | kallikrein-related peptidase 11 | 0.0108927 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0108184 |
| HIST1H2BD | histone cluster 1, H2bd | 0.0107436 |
| CRYAB | crystallin, alpha B | 0.0107302 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.0106787 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.0105864 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0103631 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0103372 |
| ADIRF | adipogenesis regulatory factor | 0.0102739 |
| KRT5 | keratin 5, type II | 0.0101004 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.0100786 |
| MT1X | metallothionein 1X | 0.00993774 |
| TMEM140 | transmembrane protein 140 | 0.00975181 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00973585 |
| IFI44L | interferon-induced protein 44-like | 0.00972586 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00962645 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00957448 |
| XIC | X chromosome inactivation center | 0.00951917 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00950478 |
| RCAN1 | regulator of calcineurin 1 | 0.00930986 |
| KRT15 | keratin 15, type I | 0.00930206 |
| KRT6A | keratin 6A, type II | 0.00913667 |
| SPRR1B | small proline-rich protein 1B | 0.00909988 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00893562 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00886411 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00885588 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00882523 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00882347 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00881798 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00875747 |
| H1-2 | H1.2 linker histone, cluster member | 0.00868681 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00865168 |
| TPD52 | tumor protein D52 | 0.00862274 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00858914 |
| CD9 | CD9 molecule | 0.00857609 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00856522 |
| HTRA1 | HtrA serine peptidase 1 | 0.00854179 |
| TRIM29 | tripartite motif containing 29 | 0.00846065 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00843076 |
| MYBPC1 | myosin binding protein C, slow type | 0.00842661 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00838841 |
| LY96 | lymphocyte antigen 96 | 0.00838581 |
| MT1G | metallothionein 1G | 0.00834323 |
| ICAM2 | intercellular adhesion molecule 2 | 0.00833935 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00831177 |
| ANXA1 | annexin A1 | 0.00826046 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00825094 |
| KRT6B | keratin 6B, type II | 0.00823424 |
| IRF1 | interferon regulatory factor 1 | 0.00823244 |
| CFB | complement factor B | 0.00820465 |
| TXNL1 | thioredoxin-like 1 | 0.00820037 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00816713 |
| CCNG2 | cyclin G2 | 0.0081037 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00808109 |
| MT1H | metallothionein 1H | 0.00807744 |
| KRT13 | keratin 13, type I | 0.0080739 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.00805933 |
| MT2A | metallothionein 2A | 0.00803462 |
| GPX1 | glutathione peroxidase 1 | 0.00801586 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.0080062 |
| MX1 | MX dynamin-like GTPase 1 | 0.00800515 |
| ITGB4 | integrin, beta 4 | 0.00800167 |
| SPRR3 | small proline-rich protein 3 | 0.00793722 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00793038 |
| BTG2 | BTG family, member 2 | 0.00786103 |
| SELE | selectin E | 0.00784462 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.0078359 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.00783482 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00783128 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00782457 |
| PITX3 | paired-like homeodomain 3 | 0.00776778 |
| RPS27L | ribosomal protein S27-like | 0.00776062 |
| DAXX | death-domain associated protein | 0.00774739 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00770912 |
| WASHC4 | WASH complex subunit 4 | 0.00766169 |
| MALL | mal, T-cell differentiation protein-like | 0.00759254 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00757966 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | 0.00757831 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00756888 |
| EFHD1 | EF-hand domain family, member D1 | 0.0075578 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.00755207 |
| CYRIA | CYFIP related Rac1 interactor A | 0.00754187 |
| ATF3 | activating transcription factor 3 | 0.00751748 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00751193 |
| SLAMF7 | SLAM family member 7 | 0.00747299 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00744656 |
| KLK6 | kallikrein-related peptidase 6 | 0.0074232 |
| GLUD1 | glutamate dehydrogenase 1 | 0.00741183 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00740045 |
| AOC1 | amine oxidase, copper containing 1 | 0.00737097 |
| RBM47 | RNA binding motif protein 47 | 0.00735584 |
| NCF2 | neutrophil cytosolic factor 2 | 0.00735375 |
| SIRT3 | sirtuin 3 | 0.00732117 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00730056 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.00727262 |
| ACTB | actin, beta | 0.00726633 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00726454 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00724351 |
| REEP5 | receptor accessory protein 5 | 0.00723759 |
| TRIM16 | tripartite motif containing 16 | 0.00722819 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00722116 |
| SH3BGR | SH3 domain binding glutamate-rich protein | 0.0071858 |
| RHCG | Rh family, C glycoprotein | 0.00718201 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00717532 |
| STOM | stomatin | 0.00715383 |
| SP110 | SP110 nuclear body protein | 0.00712395 |
| S100P | S100 calcium binding protein P | 0.00710052 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00709385 |
| KRT16 | keratin 16, type I | 0.00706949 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00705185 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00701 |
| KRT17 | keratin 17, type I | 0.00700053 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | 0.00694828 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | 0.00693728 |
| MYO1C | myosin IC | 0.00693651 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.00690413 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00690149 |
| GHITM | growth hormone inducible transmembrane protein | 0.00689771 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00686538 |
| S100A14 | S100 calcium binding protein A14 | 0.00686529 |
| CLU | clusterin | 0.00685636 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00681741 |
| OPTN | optineurin | 0.00681595 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00679275 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | 0.00675839 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00674067 |
| KRT23 | keratin 23, type I | 0.00670441 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00669989 |
| KIFAP3 | kinesin-associated protein 3 | 0.00669085 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.0066671 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00666358 |
| CYBB | cytochrome b-245, beta polypeptide | 0.00664903 |
| COX5B | cytochrome c oxidase subunit Vb | 0.00662671 |
| AFF1 | AF4/FMR2 family, member 1 | 0.00662419 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00662303 |
| STXBP2 | syntaxin binding protein 2 | 0.00662063 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00660941 |
| IL15 | interleukin 15 | 0.00659656 |
| MYOF | myoferlin | 0.00656913 |
| ADM | adrenomedullin | 0.00655951 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.00655778 |
| TARP | TCR gamma alternate reading frame protein | 0.00652883 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00652471 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00652188 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00651735 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00651585 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00650521 |
| FN1 | fibronectin 1 | 0.00649811 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00649677 |
| RIOK3 | RIO kinase 3 | 0.00648986 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00646845 |
| LST1 | leukocyte specific transcript 1 | 0.00646312 |
| IFI44 | interferon-induced protein 44 | 0.00645767 |
| GTF3A | general transcription factor IIIA | 0.00644936 |
| TSPAN7 | tetraspanin 7 | 0.00643075 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | 0.00642307 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.006411 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00639583 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00637606 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00636903 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00636328 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.00636014 |
| GIMAP4 | GTPase, IMAP family member 4 | 0.00634706 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00633776 |
| H1-0 | H1.0 linker histone | 0.00632098 |
| KYNU | kynureninase | 0.0062832 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0062574 |
| CLTB | clathrin, light chain B | 0.00625204 |
| PYCARD | PYD and CARD domain containing | 0.00625126 |
| COL11A1 | collagen, type XI, alpha 1 | 0.00624232 |
| SLN | sarcolipin | 0.00624097 |
| KLK12 | kallikrein-related peptidase 12 | 0.00624076 |
| RRAS | related RAS viral (r-ras) oncogene homolog | 0.00623741 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | 0.00623275 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 0.00623139 |
| BBX | bobby sox homolog (Drosophila) | 0.00620093 |
| GM2A | GM2 ganglioside activator | 0.00619705 |
| XBP1 | X-box binding protein 1 | 0.00615219 |
| CLDN8 | claudin 8 | 0.00614673 |
| S100A2 | S100 calcium binding protein A2 | 0.0061067 |
| CEPT1 | choline/ethanolamine phosphotransferase 1 | 0.00610258 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00609722 |
| DSG3 | desmoglein 3 | 0.00609345 |
| SPRR1A | small proline-rich protein 1A | 0.00609253 |
| KLK13 | kallikrein-related peptidase 13 | 0.00608799 |
| VAMP5 | vesicle-associated membrane protein 5 | 0.00607874 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00607506 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00606763 |
| ATG4A | autophagy related 4A, cysteine peptidase | 0.00606535 |
| CD38 | CD38 molecule | 0.00605611 |
| DUSP5 | dual specificity phosphatase 5 | 0.00605335 |
| LMBRD1 | LMBR1 domain containing 1 | 0.00605222 |
| TSG101 | tumor susceptibility 101 | 0.00605173 |
| CHPT1 | choline phosphotransferase 1 | 0.00605139 |
| RAB29 | RAB29, member RAS oncogene family | 0.00604777 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00604272 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | 0.00598841 |
| TPM2 | tropomyosin 2 (beta) | 0.00598482 |
| PPL | periplakin | 0.00597632 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00597595 |
| CSTB | cystatin B (stefin B) | 0.00596725 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00595857 |
| BPGM | 2,3-bisphosphoglycerate mutase | 0.00593593 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.00590922 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00590916 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.00589985 |
| CTBS | chitobiase, di-N-acetyl- | 0.00589961 |
| WBP1L | WW domain binding protein 1-like | 0.00589924 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.00589864 |
| APOL2 | apolipoprotein L, 2 | 0.00589024 |
| RABAC1 | Rab acceptor 1 (prenylated) | 0.00586251 |
| IRF7 | interferon regulatory factor 7 | 0.00584906 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | 0.00584775 |
| LYPD3 | LY6/PLAUR domain containing 3 | 0.00584457 |
| TRIM22 | tripartite motif containing 22 | 0.00583293 |
| LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 | 0.00581714 |
| CSTA | cystatin A (stefin A) | 0.00581112 |
| DSC2 | desmocollin 2 | 0.00581079 |
| IFI35 | interferon-induced protein 35 | 0.00578853 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00578738 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0180695 |
| MAP7 | microtubule-associated protein 7 | -0.0131942 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0125224 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.0119786 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.0115336 |
| GOLGA8A | golgin A8 family, member A | -0.0110749 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00992028 |
| FASN | fatty acid synthase | -0.00991431 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00944878 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00914463 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00909306 |
| TARDBP | TAR DNA binding protein | -0.00862527 |
| FABP6 | fatty acid binding protein 6, ileal | -0.00862464 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00854257 |
| POSTN | periostin, osteoblast specific factor | -0.00849214 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00845837 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00835293 |
| NELL2 | NEL-like 2 (chicken) | -0.00816861 |
| DUSP2 | dual specificity phosphatase 2 | -0.00809381 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00804387 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.00796544 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00795191 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.0078878 |
| SDC2 | syndecan 2 | -0.00781565 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 | -0.00772994 |
| ASRGL1 | asparaginase like 1 | -0.00761625 |
| BEX1 | brain expressed, X-linked 1 | -0.0076086 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00760283 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.00759883 |
| CCND2 | cyclin D2 | -0.00756506 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00753008 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00739879 |
| SRSF6 | serine/arginine-rich splicing factor 6 | -0.00738245 |
| CYTH1 | cytohesin 1 | -0.00734772 |
| PNN | pinin, desmosome associated protein | -0.00733583 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.0073044 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.00716706 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00702292 |
| PRKD3 | protein kinase D3 | -0.00694339 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00693793 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.00690619 |
| HP | haptoglobin | -0.00686337 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 | -0.00684308 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00683287 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00680436 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00679555 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00675618 |
| YEATS4 | YEATS domain containing 4 | -0.00673231 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00672847 |
| NPTX1 | neuronal pentraxin I | -0.00672569 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00666945 |
| CPE | carboxypeptidase E | -0.00666587 |
| PLXNA1 | plexin A1 | -0.00663617 |
| CADM1 | cell adhesion molecule 1 | -0.00660263 |
| NOTCH2NL | notch 2 N-terminal like | -0.00659281 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.0065903 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.0065038 |
| CD320 | CD320 molecule | -0.00646698 |
| NCALD | neurocalcin delta | -0.00646589 |
| C4BPA | complement component 4 binding protein, alpha | -0.00644761 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) | -0.00644461 |
| SNX7 | sorting nexin 7 | -0.00644065 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein | -0.00642749 |
| HMGB3 | high mobility group box 3 | -0.00641053 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00640972 |
| MEIS2 | Meis homeobox 2 | -0.00636272 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00634207 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00633817 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.00630689 |
| APOA1 | apolipoprotein A-I | -0.00628622 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00625508 |
| XYLT1 | xylosyltransferase I | -0.00625158 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00623023 |
| AUTS2 | autism susceptibility candidate 2 | -0.0062174 |
| CHKB | choline kinase beta | -0.00621401 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.00620727 |
| ZNF266 | zinc finger protein 266 | -0.00620541 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00620064 |
| GSTM1 | glutathione S-transferase mu 1 | -0.00617396 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00615749 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | -0.00613332 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.00612437 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | -0.00609921 |
| GCH1 | GTP cyclohydrolase 1 | -0.00608173 |
| RPL10 | ribosomal protein L10 | -0.00608023 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00602157 |
| HOPX | HOP homeobox | -0.00600203 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00599415 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00597319 |
| CTPS1 | CTP synthase 1 | -0.00597217 |
| SFTPC | surfactant protein C | -0.00596682 |
| RBL2 | retinoblastoma-like 2 | -0.00596601 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.0059621 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00596063 |
| PRKCZ | protein kinase C, zeta | -0.00595123 |
| ZNF83 | zinc finger protein 83 | -0.00594239 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.0059176 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.0059142 |
| RACGAP1 | Rac GTPase activating protein 1 | -0.00589192 |
| BCHE | butyrylcholinesterase | -0.00587107 |
| HCRT | hypocretin (orexin) neuropeptide precursor | -0.0058586 |
| TSPAN12 | tetraspanin 12 | -0.00584576 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.00584573 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00583857 |
| NPTX2 | neuronal pentraxin II | -0.00583716 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha | -0.00583462 |
| PAEP | progestagen-associated endometrial protein | -0.00582797 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.00581808 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00578948 |
| FBXO21 | F-box protein 21 | -0.00577608 |
| DMBT1 | deleted in malignant brain tumors 1 | -0.00575034 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | -0.00574007 |
| EMID1 | EMI domain containing 1 | -0.00573673 |
| PRAME | preferentially expressed antigen in melanoma | -0.00572874 |
| FBXO11 | F-box protein 11 | -0.00572542 |
| FZD2 | frizzled class receptor 2 | -0.00572236 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00569519 |
| MPZL2 | myelin protein zero-like 2 | -0.00569474 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00569424 |
| PTK2 | protein tyrosine kinase 2 | -0.00568381 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00567006 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.00566905 |
| GPC3 | glypican 3 | -0.00566453 |
| CCNL2 | cyclin L2 | -0.00565945 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -0.00565436 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | -0.00561925 |
| SI | sucrase-isomaltase (alpha-glucosidase) | -0.00561304 |
| CAMP | cathelicidin antimicrobial peptide | -0.00560655 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.0056049 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | -0.00559829 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) | -0.00559652 |
| OLFM1 | olfactomedin 1 | -0.00559485 |
| CLCA1 | chloride channel accessory 1 | -0.0055919 |
| NTS | neurotensin | -0.00559095 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00558935 |
| IFT81 | intraflagellar transport 81 | -0.00558535 |
| TBC1D16 | TBC1 domain family, member 16 | -0.00558025 |
| ACTL6A | actin-like 6A | -0.00557004 |
| WT1 | Wilms tumor 1 | -0.0055614 |
| TLE2 | transducin-like enhancer of split 2 | -0.00554337 |
| TRAF5 | TNF receptor-associated factor 5 | -0.00553995 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.00553454 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00552681 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.0055155 |
| LAMA4 | laminin, alpha 4 | -0.00551332 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00549109 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.00548911 |
| TNC | tenascin C | -0.00548843 |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) | -0.00548093 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00546918 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00546001 |
| SPAG5 | sperm associated antigen 5 | -0.00545938 |
| IRF8 | interferon regulatory factor 8 | -0.00545084 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00543838 |
| POGLUT2 | protein O-glucosyltransferase 2 | -0.00543828 |
| USP36 | ubiquitin specific peptidase 36 | -0.00543757 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.00543561 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.0054171 |
| MECOM | MDS1 and EVI1 complex locus | -0.00541451 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00541356 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0054084 |
| CERK | ceramide kinase | -0.00538907 |
| DGAT1 | diacylglycerol O-acyltransferase 1 | -0.0053864 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0053805 |
| RUSC1 | RUN and SH3 domain containing 1 | -0.00537679 |
| SLC35E2B | solute carrier family 35, member E2B | -0.00534106 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | -0.00529532 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.00528626 |
| STXBP6 | syntaxin binding protein 6 (amisyn) | -0.00528511 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.00528494 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.00527976 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.00527388 |
| VLDLR | very low density lipoprotein receptor | -0.00527261 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | -0.00526822 |
| B3GNT1 | -0.00526506 | |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00526329 |
| PRELID3B | PRELI domain containing 3B | -0.00525217 |
| TRAF4 | TNF receptor-associated factor 4 | -0.00524025 |
| CRMP1 | collapsin response mediator protein 1 | -0.00523296 |
| DNM1 | dynamin 1 | -0.00523063 |
| APOB | apolipoprotein B | -0.00521062 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.00520824 |
| H2AX | H2A.X variant histone | -0.0052067 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | -0.00520349 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.00519944 |
| LYZ | lysozyme | -0.00519857 |
| C7 | complement component 7 | -0.00519359 |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 | -0.00517898 |
| APMAP | adipocyte plasma membrane associated protein | -0.00517276 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.00515324 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.00514932 |
| ACO1 | aconitase 1, soluble | -0.00514916 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00513935 |
| KANSL2 | KAT8 regulatory NSL complex subunit 2 | -0.00513632 |
| CHKA | choline kinase alpha | -0.00511997 |
| PASK | PAS domain containing serine/threonine kinase | -0.00511788 |
| IL1R1 | interleukin 1 receptor, type I | -0.00511331 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | -0.00510961 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | -0.00510716 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | -0.0050887 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.00508016 |
| SKI | SKI proto-oncogene | -0.00507749 |
| HOXB6 | homeobox B6 | -0.00507651 |
| EPCAM | epithelial cell adhesion molecule | -0.0050669 |
| THAP12 | THAP domain containing 12 | -0.00505801 |
| MEIS1 | Meis homeobox 1 | -0.00505707 |
| HOXB7 | homeobox B7 | -0.00504158 |
| RAPSN | receptor-associated protein of the synapse | -0.00503815 |
| LIMA1 | LIM domain and actin binding 1 | -0.00502265 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | -0.00500987 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -0.00498753 |
| APOC3 | apolipoprotein C-III | -0.00498221 |
| MAOA | monoamine oxidase A | -0.00497796 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00497219 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00497177 |
| EFNB3 | ephrin-B3 | -0.00496094 |
| TMEM204 | transmembrane protein 204 | -0.0049555 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.00493328 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 | -0.00491447 |
| AURKB | aurora kinase B | -0.0049124 |
| IPO5 | importin 5 | -0.00490237 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00490223 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00490208 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | -0.00489935 |
| TCF4 | transcription factor 4 | -0.00487781 |
| KLHL23 | kelch-like family member 23 | -0.00487444 |
| COL4A1 | collagen, type IV, alpha 1 | -0.00487325 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00487184 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00487182 |
| DGKZ | diacylglycerol kinase, zeta | -0.00486077 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.00485261 |
| MMP2 | matrix metallopeptidase 2 | -0.00484563 |
| DENND4B | DENN/MADD domain containing 4B | -0.00484373 |
| CBX6 | chromobox homolog 6 | -0.00484217 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 | -0.00483513 |
| NUP107 | nucleoporin 107kDa | -0.00482919 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | -0.00481496 |
| DPP3 | dipeptidyl-peptidase 3 | -0.00481345 |
| PRKCB | protein kinase C, beta | -0.00480781 |
| GPM6A | glycoprotein M6A | -0.00480501 |
| PGC | progastricsin (pepsinogen C) | -0.0047839 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.00477582 |
| ELAC2 | elaC ribonuclease Z 2 | -0.00477168 |
| NOTCH2 | notch 2 | -0.00476791 |
| SCAF4 | SR-related CTD-associated factor 4 | -0.00475601 |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) | -0.00475339 |
| GPR161 | G protein-coupled receptor 161 | -0.00475147 |
| SMTN | smoothelin | -0.00474956 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00474666 |
| MAPK9 | mitogen-activated protein kinase 9 | -0.00473226 |