| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | hepatocyte nuclear factor 4, alpha|The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012] (NCBI Entrez Gene Database, 3172) |
| External Link | https://ncbi.nlm.nih.gov/gene/3172 |
| Similar Terms | |
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499 genes differentially expressed following the HNF4A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.0145061 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0120374 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0118714 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.011587 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0109456 |
| GAS1 | growth arrest-specific 1 | 0.0108243 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.0100941 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00989354 |
| TOB1 | transducer of ERBB2, 1 | 0.00973018 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00947627 |
| CCN2 | cellular communication network factor 2 | 0.0093232 |
| G0S2 | G0/G1 switch 2 | 0.00931185 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 0.00907532 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00905025 |
| ADIRF | adipogenesis regulatory factor | 0.00896851 |
| KRT23 | keratin 23, type I | 0.00889369 |
| HOXC6 | homeobox C6 | 0.00888808 |
| TSPYL5 | TSPY-like 5 | 0.00882329 |
| MT1X | metallothionein 1X | 0.00877184 |
| MFAP5 | microfibrillar associated protein 5 | 0.00871933 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00864434 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00861452 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00853802 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0084521 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00828751 |
| BLNK | B-cell linker | 0.0081802 |
| WDR7 | WD repeat domain 7 | 0.00812707 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | 0.00798781 |
| ASS1 | argininosuccinate synthase 1 | 0.00797972 |
| PCDH9 | protocadherin 9 | 0.00794161 |
| SCAND1 | SCAN domain containing 1 | 0.00785209 |
| TXLNA | taxilin alpha | 0.00784333 |
| METRN | meteorin, glial cell differentiation regulator | 0.00782899 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00779386 |
| THBS2 | thrombospondin 2 | 0.00778996 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00777769 |
| APOD | apolipoprotein D | 0.00768866 |
| RTN1 | reticulon 1 | 0.00768417 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.00766734 |
| INSR | insulin receptor | 0.00756991 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.00756931 |
| NID2 | nidogen 2 (osteonidogen) | 0.00753284 |
| PROM1 | prominin 1 | 0.00751496 |
| CAV2 | caveolin 2 | 0.00739985 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00729922 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | 0.00722164 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00714825 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.00702877 |
| MX1 | MX dynamin-like GTPase 1 | 0.00699852 |
| GPM6B | glycoprotein M6B | 0.00699286 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00696979 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00696893 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.00695218 |
| ESR1 | estrogen receptor 1 | 0.00688929 |
| LY75 | lymphocyte antigen 75 | 0.00688838 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00684363 |
| TPD52L1 | tumor protein D52-like 1 | 0.00684159 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00683978 |
| AEBP1 | AE binding protein 1 | 0.00680884 |
| ADD3 | adducin 3 (gamma) | 0.00678724 |
| SMAD2 | SMAD family member 2 | 0.00677792 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00677148 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00667322 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00662472 |
| BBX | bobby sox homolog (Drosophila) | 0.00660233 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00658438 |
| ELOVL2 | ELOVL fatty acid elongase 2 | 0.00652699 |
| ANXA1 | annexin A1 | 0.00652358 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00643966 |
| CA12 | carbonic anhydrase XII | 0.00640774 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00637604 |
| PIP | prolactin-induced protein | 0.00634161 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | 0.0063346 |
| RCAN1 | regulator of calcineurin 1 | 0.0063326 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00632012 |
| MEX3C | mex-3 RNA binding family member C | 0.00631968 |
| ABAT | 4-aminobutyrate aminotransferase | 0.0062992 |
| ZNF423 | zinc finger protein 423 | 0.00625485 |
| CHRDL1 | chordin-like 1 | 0.00623074 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | 0.00621996 |
| KRT7 | keratin 7, type II | 0.00621925 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00620951 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00616809 |
| TAC1 | tachykinin, precursor 1 | 0.00614182 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00613371 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 0.00611024 |
| DCLK1 | doublecortin-like kinase 1 | 0.0060638 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00601791 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00599661 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00597619 |
| MATN2 | matrilin 2 | 0.00597436 |
| MXRA5 | matrix-remodelling associated 5 | 0.00595176 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00592841 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00591741 |
| CALB1 | calbindin 1, 28kDa | 0.00590659 |
| TFF1 | trefoil factor 1 | 0.00589276 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00589169 |
| COL16A1 | collagen, type XVI, alpha 1 | 0.005891 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00588625 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0058774 |
| GRB14 | growth factor receptor-bound protein 14 | 0.00586567 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00585146 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00584999 |
| GPR137B | G protein-coupled receptor 137B | 0.0058357 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00580003 |
| MLF1 | myeloid leukemia factor 1 | 0.0057698 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00576244 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.00575104 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | 0.00571155 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0056888 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00568608 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00568201 |
| ZNF165 | zinc finger protein 165 | 0.00567827 |
| COBL | cordon-bleu WH2 repeat protein | 0.00567746 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00567649 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00565919 |
| BEX1 | brain expressed, X-linked 1 | 0.00565256 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00559744 |
| BRD2 | bromodomain containing 2 | 0.00559613 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00558447 |
| LACTB2 | lactamase, beta 2 | 0.00557511 |
| S100P | S100 calcium binding protein P | 0.00555096 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 0.00551275 |
| NDUFB8 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa | 0.0055014 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | 0.00549965 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00549919 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.0054815 |
| MT1H | metallothionein 1H | 0.00548033 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00547935 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00546571 |
| FA2H | fatty acid 2-hydroxylase | 0.00544506 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.00542243 |
| CFD | complement factor D (adipsin) | 0.00541718 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.00539712 |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs | 0.00539445 |
| BEX4 | brain expressed, X-linked 4 | 0.00539041 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00538832 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00538107 |
| FOXD1 | forkhead box D1 | 0.00537127 |
| MUC16 | mucin 16, cell surface associated | 0.00537117 |
| MMP9 | matrix metallopeptidase 9 | 0.00535146 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.0053327 |
| WWOX | WW domain containing oxidoreductase | 0.00532198 |
| EGR1 | early growth response 1 | 0.00527727 |
| CD200 | CD200 molecule | 0.00527562 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00527515 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.00525715 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | 0.00524811 |
| CP | ceruloplasmin (ferroxidase) | 0.00524479 |
| CLEC3B | C-type lectin domain family 3, member B | 0.00523931 |
| ASRGL1 | asparaginase like 1 | 0.00523785 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) | 0.0052274 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00520864 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.00520247 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.00518625 |
| SGCE | sarcoglycan, epsilon | 0.00517256 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00516333 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00514332 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0051262 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00512507 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.00511169 |
| ACKR3 | atypical chemokine receptor 3 | 0.00511159 |
| HOMER1 | homer scaffolding protein 1 | 0.00511132 |
| PHF20 | PHD finger protein 20 | 0.00510479 |
| GOLGA8H | golgin A8 family, member H | 0.0051019 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 0.00509986 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.00509799 |
| MEOX2 | mesenchyme homeobox 2 | 0.0050861 |
| CLU | clusterin | 0.00507239 |
| TBCA | tubulin folding cofactor A | 0.00507039 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00507031 |
| KRT14 | keratin 14, type I | 0.00505847 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00502815 |
| LAMC2 | laminin, gamma 2 | 0.00500854 |
| DCN | decorin | 0.00500332 |
| IL1B | interleukin 1, beta | 0.0049829 |
| ANK2 | ankyrin 2, neuronal | 0.00497765 |
| RAB29 | RAB29, member RAS oncogene family | 0.00496059 |
| RPS27L | ribosomal protein S27-like | 0.00494175 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00493197 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00492213 |
| C5ORF30 | chromosome 5 open reading frame 30 | 0.00492046 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | 0.00491824 |
| NAP1L3 | nucleosome assembly protein 1-like 3 | 0.00491406 |
| PDLIM4 | PDZ and LIM domain 4 | 0.00491355 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.00491037 |
| THBS4 | thrombospondin 4 | 0.00489122 |
| EHD3 | EH-domain containing 3 | 0.00487901 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00487375 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00485102 |
| CALCA | calcitonin-related polypeptide alpha | 0.00484867 |
| CLDN1 | claudin 1 | 0.00482288 |
| C9ORF16 | chromosome 9 open reading frame 16 | 0.00482281 |
| SYT1 | synaptotagmin I | 0.00480543 |
| CLIC5 | chloride intracellular channel 5 | 0.00479636 |
| OPN3 | opsin 3 | 0.00479324 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00478247 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 0.00477979 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00477886 |
| XIC | X chromosome inactivation center | 0.00477645 |
| CCND3 | cyclin D3 | 0.00474113 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00474084 |
| MT1F | metallothionein 1F | 0.00473947 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.00473908 |
| MT1G | metallothionein 1G | 0.00473632 |
| FBLN2 | fibulin 2 | 0.00473438 |
| GPX4 | glutathione peroxidase 4 | 0.00472324 |
| CFAP20 | cilia and flagella associated protein 20 | 0.00470951 |
| KLHL24 | kelch-like family member 24 | 0.00470118 |
| GRAMD2B | GRAM domain containing 2B | 0.0046925 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00467516 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00465321 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00463321 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00463113 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.004622 |
| CTBP2 | C-terminal binding protein 2 | 0.00460859 |
| RFK | riboflavin kinase | 0.00459989 |
| FBXO2 | F-box protein 2 | 0.00459492 |
| PLSCR4 | phospholipid scramblase 4 | 0.0045921 |
| MAGED2 | melanoma antigen family D2 | 0.00459006 |
| SRPK2 | SRSF protein kinase 2 | 0.00459004 |
| PTGES | prostaglandin E synthase | 0.00458816 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 | 0.00458656 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00457756 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.00457756 |
| NFIB | nuclear factor I/B | 0.00457685 |
| SGPL1 | sphingosine-1-phosphate lyase 1 | 0.00456451 |
| KLC1 | kinesin light chain 1 | 0.00455031 |
| JMJD1C | jumonji domain containing 1C | 0.00455027 |
| KRT19 | keratin 19, type I | 0.00454688 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.00454286 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00454206 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.00454107 |
| LHFP | lipoma HMGIC fusion partner | 0.0045335 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.00452978 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.00451513 |
| CFB | complement factor B | 0.0045064 |
| GRAMD1C | GRAM domain containing 1C | 0.00450549 |
| CRY1 | cryptochrome circadian clock 1 | 0.00450547 |
| MMP10 | matrix metallopeptidase 10 | 0.00449696 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00448738 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | 0.00448279 |
| OPTN | optineurin | 0.0044614 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 0.00446029 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | 0.00445808 |
| PAX5 | paired box 5 | 0.00445293 |
| AHCY | adenosylhomocysteinase | 0.00444929 |
| VPREB1 | pre-B lymphocyte 1 | 0.00444574 |
| IL6R | interleukin 6 receptor | 0.00444436 |
| TUBB2A | tubulin, beta 2A class IIa | 0.0044437 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0128028 |
| SFTPA2 | surfactant protein A2 | -0.0112564 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00976611 |
| HOPX | HOP homeobox | -0.00962408 |
| TGFB1 | transforming growth factor, beta 1 | -0.00960137 |
| CDC20 | cell division cycle 20 | -0.00916519 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00887453 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00880008 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00861919 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00859597 |
| COPS7A | COP9 signalosome subunit 7A | -0.00843792 |
| SFTPB | surfactant protein B | -0.00841537 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00833075 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00793801 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0076933 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.00768406 |
| GSPT1 | G1 to S phase transition 1 | -0.00763457 |
| PLBD1 | phospholipase B domain containing 1 | -0.0073544 |
| ACTB | actin, beta | -0.00735272 |
| SFTPD | surfactant protein D | -0.00712033 |
| DMBT1 | deleted in malignant brain tumors 1 | -0.00707492 |
| PRC1 | protein regulator of cytokinesis 1 | -0.00700912 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00693808 |
| HMGB2 | high mobility group box 2 | -0.00693628 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.00691319 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.0069096 |
| SFTPC | surfactant protein C | -0.00686182 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.0068532 |
| CHKB | choline kinase beta | -0.00683915 |
| TCTA | T-cell leukemia translocation altered | -0.00681615 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0067321 |
| XPO7 | exportin 7 | -0.00671283 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00663203 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00651556 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00647744 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00643754 |
| NPR3 | natriuretic peptide receptor 3 | -0.00641414 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00641214 |
| SLN | sarcolipin | -0.00639771 |
| FOXF1 | forkhead box F1 | -0.00635381 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | -0.00625398 |
| POSTN | periostin, osteoblast specific factor | -0.00622886 |
| PGC | progastricsin (pepsinogen C) | -0.00620694 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | -0.00620154 |
| MEX3D | mex-3 RNA binding family member D | -0.00611745 |
| S100A8 | S100 calcium binding protein A8 | -0.00607776 |
| TCF21 | transcription factor 21 | -0.00605385 |
| FABP7 | fatty acid binding protein 7, brain | -0.00604994 |
| RANBP1 | RAN binding protein 1 | -0.00601752 |
| FOXF2 | forkhead box F2 | -0.00600759 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.005987 |
| TLR4 | toll-like receptor 4 | -0.0059559 |
| GPC3 | glypican 3 | -0.0058841 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.00588366 |
| FOLR1 | folate receptor 1 (adult) | -0.00586965 |
| NDNF | neuron-derived neurotrophic factor | -0.00581086 |
| SIRT3 | sirtuin 3 | -0.00578172 |
| TPM4 | tropomyosin 4 | -0.00577582 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00575158 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.00574907 |
| TMPRSS2 | transmembrane protease, serine 2 | -0.00574335 |
| FOXM1 | forkhead box M1 | -0.00570996 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00569966 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.00569424 |
| KRT18 | keratin 18, type I | -0.00568953 |
| TUG1 | taurine up-regulated 1 (non-protein coding) | -0.00567685 |
| HBD | hemoglobin, delta | -0.0056742 |
| S100A9 | S100 calcium binding protein A9 | -0.0056527 |
| HNMT | histamine N-methyltransferase | -0.00563926 |
| NLRP2 | NLR family, pyrin domain containing 2 | -0.00560058 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00557183 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.00556807 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00555584 |
| TARP | TCR gamma alternate reading frame protein | -0.0055429 |
| ODC1 | ornithine decarboxylase 1 | -0.00553822 |
| GGT1 | gamma-glutamyltransferase 1 | -0.00551803 |
| FZD5 | frizzled class receptor 5 | -0.00549711 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00538349 |
| MALL | mal, T-cell differentiation protein-like | -0.00538185 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.0053651 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00533901 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | -0.00531264 |
| CLCN3 | chloride channel, voltage-sensitive 3 | -0.00528354 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00527898 |
| SPRR1B | small proline-rich protein 1B | -0.00522926 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00522621 |
| TMEM14B | transmembrane protein 14B | -0.00520312 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 | -0.00518563 |
| NPTX1 | neuronal pentraxin I | -0.00517896 |
| IL2RB | interleukin 2 receptor, beta | -0.00516524 |
| LMNB1 | lamin B1 | -0.00515609 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa | -0.00513602 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 | -0.00513106 |
| EPAS1 | endothelial PAS domain protein 1 | -0.00511054 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00509983 |
| PGD | phosphogluconate dehydrogenase | -0.00508525 |
| MAPK1 | mitogen-activated protein kinase 1 | -0.00507673 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00504324 |
| NELFCD | negative elongation factor complex member C/D | -0.00499635 |
| CA9 | carbonic anhydrase IX | -0.00499583 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00499356 |
| CLIC3 | chloride intracellular channel 3 | -0.00496158 |
| CHRM3 | cholinergic receptor, muscarinic 3 | -0.00493918 |
| NKX2-1 | NK2 homeobox 1 | -0.00493709 |
| S100A2 | S100 calcium binding protein A2 | -0.00491074 |
| ANOS1 | anosmin 1 | -0.00490535 |
| DENND2B | DENN domain containing 2B | -0.00486955 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00485621 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.00485557 |
| MTCL1 | microtubule crosslinking factor 1 | -0.00484744 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00484067 |
| ZDHHC4 | zinc finger, DHHC-type containing 4 | -0.0048343 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | -0.00482127 |
| TTLL12 | tubulin tyrosine ligase-like family member 12 | -0.00481202 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | -0.00479218 |
| UNC13B | unc-13 homolog B (C. elegans) | -0.00479016 |
| CD34 | CD34 molecule | -0.00478399 |
| AHSP | alpha hemoglobin stabilizing protein | -0.00475219 |
| PDGFC | platelet derived growth factor C | -0.00474972 |
| CLTC | clathrin, heavy chain (Hc) | -0.0047404 |
| COL1A2 | collagen, type I, alpha 2 | -0.00471165 |
| TSPAN4 | tetraspanin 4 | -0.00470656 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00470602 |
| KIF20A | kinesin family member 20A | -0.00468512 |
| RUSF1 | RUS family member 1 | -0.00467286 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00466278 |
| ACP3 | acid phosphatase 3 | -0.00465989 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00464275 |
| EMID1 | EMI domain containing 1 | -0.00463461 |
| TSPAN6 | tetraspanin 6 | -0.00460474 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00458482 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00457826 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00457248 |
| SPRR3 | small proline-rich protein 3 | -0.00454391 |
| PRF1 | perforin 1 (pore forming protein) | -0.0045291 |
| EXPH5 | exophilin 5 | -0.00452812 |
| CNTN1 | contactin 1 | -0.00451079 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.00450454 |
| CD177 | CD177 molecule | -0.00447648 |
| PPP1R11 | protein phosphatase 1, regulatory (inhibitor) subunit 11 | -0.00447349 |
| FAM13A | family with sequence similarity 13, member A | -0.00446244 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | -0.00445906 |
| LOXL2 | lysyl oxidase-like 2 | -0.00445652 |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | -0.00444669 |
| GANAB | glucosidase, alpha; neutral AB | -0.00444498 |
| SPRR2B | small proline-rich protein 2B | -0.0044407 |
| ATP6V0C | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | -0.00443982 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00443677 |
| GNLY | granulysin | -0.00443242 |
| ARSL | arylsulfatase L | -0.0044314 |
| NES | nestin | -0.00441969 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00441834 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00441526 |
| FOXA2 | forkhead box A2 | -0.00440769 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00434266 |
| PARVB | parvin, beta | -0.00434083 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | -0.00432463 |
| KLHDC3 | kelch domain containing 3 | -0.00432094 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00432014 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00431872 |
| BMP4 | bone morphogenetic protein 4 | -0.00431852 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | -0.00431634 |
| NUCB1 | nucleobindin 1 | -0.00431216 |
| RPS5 | ribosomal protein S5 | -0.00430918 |
| SUMO1 | small ubiquitin-like modifier 1 | -0.00430466 |
| MAP7 | microtubule-associated protein 7 | -0.00428079 |
| LTA4H | leukotriene A4 hydrolase | -0.0042807 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00427873 |
| EPHA4 | EPH receptor A4 | -0.0042771 |
| TNNC1 | troponin C type 1 (slow) | -0.00427182 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.0042406 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | -0.00422156 |
| METTL9 | methyltransferase like 9 | -0.00421828 |
| COL4A6 | collagen, type IV, alpha 6 | -0.00421748 |
| FAM198B | family with sequence similarity 198, member B | -0.0042029 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.00420034 |
| JOSD1 | Josephin domain containing 1 | -0.00419817 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) | -0.00418729 |
| ADM | adrenomedullin | -0.00418722 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -0.00418561 |
| CLCA4 | chloride channel accessory 4 | -0.00418437 |
| DAPK1 | death-associated protein kinase 1 | -0.00417426 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00417379 |
| NOP10 | NOP10 ribonucleoprotein | -0.00417143 |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 | -0.00416833 |
| GLS | glutaminase | -0.00416816 |
| ROGDI | rogdi homolog (Drosophila) | -0.00416623 |
| PHB2 | prohibitin 2 | -0.00415221 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | -0.00413821 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00413172 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.00413129 |
| PTK7 | protein tyrosine kinase 7 (inactive) | -0.00411706 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | -0.00410612 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00409695 |
| ZWINT | ZW10 interacting kinetochore protein | -0.00409193 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00408606 |
| PKM | pyruvate kinase, muscle | -0.00408339 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | -0.00408217 |
| CSK | c-src tyrosine kinase | -0.00406888 |
| CCKBR | cholecystokinin B receptor | -0.00406095 |
| PLXNA2 | plexin A2 | -0.00405405 |
| DSC2 | desmocollin 2 | -0.00404638 |
| KLF1 | Kruppel-like factor 1 (erythroid) | -0.00404453 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00403846 |
| TPI1 | triosephosphate isomerase 1 | -0.00402735 |
| C4BPA | complement component 4 binding protein, alpha | -0.00402531 |
| UBB | ubiquitin B | -0.00402525 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00402381 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.00401737 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00401474 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | -0.00401354 |
| COL3A1 | collagen, type III, alpha 1 | -0.00398944 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00398903 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.0039877 |
| PRDX6 | peroxiredoxin 6 | -0.00397655 |
| GPM6A | glycoprotein M6A | -0.00397645 |
| LST1 | leukocyte specific transcript 1 | -0.00397105 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00396798 |
| ENG | endoglin | -0.00396257 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | -0.0039609 |
| RACGAP1 | Rac GTPase activating protein 1 | -0.00395585 |
| TTN | titin | -0.00395129 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0039496 |
| HMBS | hydroxymethylbilane synthase | -0.00394044 |
| CHN1 | chimerin 1 | -0.00393911 |
| TEAD4 | TEA domain family member 4 | -0.00393649 |
| DIO2 | deiodinase, iodothyronine, type II | -0.0039361 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00391334 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00391291 |
| RNF187 | ring finger protein 187 | -0.00391097 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00391094 |
| SLC10A3 | solute carrier family 10, member 3 | -0.00390612 |
| TEX261 | testis expressed 261 | -0.00390584 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00390529 |
| OCA2 | oculocutaneous albinism II | -0.0039034 |
| TAL1 | T-cell acute lymphocytic leukemia 1 | -0.00390009 |
| H2AX | H2A.X variant histone | -0.00389994 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.00389181 |
| SELENBP1 | selenium binding protein 1 | -0.00388895 |
| LOX | lysyl oxidase | -0.00388581 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00388309 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00387167 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.00387088 |
| MLST8 | MTOR associated protein, LST8 homolog (S. cerevisiae) | -0.00386873 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.0038663 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | -0.00386283 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | -0.0038607 |
| NMU | neuromedin U | -0.00385288 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.00384923 |