HNMPA-(AM)3-583 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

192 genes differentially expressed following the HNMPA-(AM)3-583 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AK1 adenylate kinase 1
ARSF arylsulfatase F
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BMP5 bone morphogenetic protein 5
C7ORF43 chromosome 7 open reading frame 43
CA14 carbonic anhydrase XIV
CD83 CD83 molecule
CD8A CD8a molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COIL coilin
COL1A2 collagen, type I, alpha 2
CORO1B coronin, actin binding protein, 1B
CRYAA crystallin, alpha A
CTNNA3 catenin (cadherin-associated protein), alpha 3
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DHRS2 dehydrogenase/reductase (SDR family) member 2
DIO2 deiodinase, iodothyronine, type II
DLX2 distal-less homeobox 2
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
ECE2 endothelin converting enzyme 2
EGR1 early growth response 1
EIF1 eukaryotic translation initiation factor 1
FAM222B family with sequence similarity 222, member B
FBXO42 F-box protein 42
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FH fumarate hydratase
FOSL2 FOS-like antigen 2
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GIMAP5 GTPase, IMAP family member 5
GLP1R glucagon-like peptide 1 receptor
GLS glutaminase
GLS2 glutaminase 2 (liver, mitochondrial)
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GRIP2 glutamate receptor interacting protein 2
GSK3A glycogen synthase kinase 3 alpha
HAB1 B1 for mucin
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HLA-E major histocompatibility complex, class I, E
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IQCK IQ motif containing K
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
JUND jun D proto-oncogene
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
KIAA1324 KIAA1324
KIF25 kinesin family member 25
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KRT5 keratin 5, type II
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRRK1 leucine-rich repeat kinase 1
MAP7 microtubule-associated protein 7
MAPK3 mitogen-activated protein kinase 3
MICALL1 MICAL-like 1
MPPE1 metallophosphoesterase 1
MUC1 mucin 1, cell surface associated
MZF1 myeloid zinc finger 1
NCKIPSD NCK interacting protein with SH3 domain
NCR3 natural cytotoxicity triggering receptor 3
NCS1 neuronal calcium sensor 1
NDRG2 NDRG family member 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PC pyruvate carboxylase
PCGF1 polycomb group ring finger 1
PDGFB platelet-derived growth factor beta polypeptide
PEX1 peroxisomal biogenesis factor 1
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PIPOX pipecolic acid oxidase
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
REST RE1-silencing transcription factor
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SIRPA signal-regulatory protein alpha
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SOX21 SRY (sex determining region Y)-box 21
SQSTM1 sequestosome 1
STC2 stanniocalcin 2
SURF2 surfeit 2
TBX5 T-box 5
TOB2 transducer of ERBB2, 2
TRIM62 tripartite motif containing 62
TSG101 tumor susceptibility 101
ULBP2 UL16 binding protein 2
USP2 ubiquitin specific peptidase 2
ZGPAT zinc finger, CCCH-type with G patch domain
ZNF528 zinc finger protein 528

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
AHSP alpha hemoglobin stabilizing protein
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ATG2B autophagy related 2B
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C12ORF29 chromosome 12 open reading frame 29
C19ORF57 chromosome 19 open reading frame 57
C2ORF54 chromosome 2 open reading frame 54
C3ORF18 chromosome 3 open reading frame 18
C5ORF45 chromosome 5 open reading frame 45
C6ORF47 chromosome 6 open reading frame 47
CA6 carbonic anhydrase VI
CBY1 chibby homolog 1 (Drosophila)
CD79A CD79a molecule, immunoglobulin-associated alpha
CDH3 cadherin 3, type 1, P-cadherin (placental)
CLDN17 claudin 17
CLDND1 claudin domain containing 1
CLIP4 CAP-GLY domain containing linker protein family, member 4
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNPY3 canopy FGF signaling regulator 3
CRYAB crystallin, alpha B
CSRNP3 cysteine-serine-rich nuclear protein 3
CTGF connective tissue growth factor
CXCL6 chemokine (C-X-C motif) ligand 6
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DNASE1L3 deoxyribonuclease I-like 3
EFNB1 ephrin-B1
EN2 engrailed homeobox 2
FGF16 fibroblast growth factor 16
FJX1 four jointed box 1 (Drosophila)
FKBP10 FK506 binding protein 10, 65 kDa
FRAS1 Fraser extracellular matrix complex subunit 1
FRMD1 FERM domain containing 1
FUBP3 far upstream element (FUSE) binding protein 3
GLT8D2 glycosyltransferase 8 domain containing 2
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPN3 GPN-loop GTPase 3
GPR21 G protein-coupled receptor 21
GPR3 G protein-coupled receptor 3
GSTCD glutathione S-transferase, C-terminal domain containing
GYPC glycophorin C (Gerbich blood group)
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HMX1 H6 family homeobox 1
HP1BP3 heterochromatin protein 1, binding protein 3
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL19 interleukin 19
IL36RN interleukin 36 receptor antagonist
JMJD4 jumonji domain containing 4
KIFC1 kinesin family member C1
KLHL26 kelch-like family member 26
LIAS lipoic acid synthetase
LYPD3 LY6/PLAUR domain containing 3
MCM10 minichromosome maintenance complex component 10
MXRA8 matrix-remodelling associated 8
NPDC1 neural proliferation, differentiation and control, 1
NVL nuclear VCP-like
NXPH4 neurexophilin 4
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PFAS phosphoribosylformylglycinamidine synthase
PISD phosphatidylserine decarboxylase
POU5F1B POU class 5 homeobox 1B
PPP1R26 protein phosphatase 1, regulatory subunit 26
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRF1 perforin 1 (pore forming protein)
PRKG2 protein kinase, cGMP-dependent, type II
QDPR quinoid dihydropteridine reductase
RGS17 regulator of G-protein signaling 17
RIN2 Ras and Rab interactor 2
RPUSD2 RNA pseudouridylate synthase domain containing 2
SAMHD1 SAM domain and HD domain 1
SCARA3 scavenger receptor class A, member 3
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SNAI2 snail family zinc finger 2
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STARD5 StAR-related lipid transfer (START) domain containing 5
STK16 serine/threonine kinase 16
T T, brachyury homolog (mouse)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TKFC triokinase/FMN cyclase
TMEM176A transmembrane protein 176A
TNS4 tensin 4
TRIM5 tripartite motif containing 5
TTC27 tetratricopeptide repeat domain 27
UBAC1 UBA domain containing 1
UPK1A uroplakin 1A
VASH2 vasohibin 2
ZC3H12A zinc finger CCCH-type containing 12A
ZFP36 ZFP36 ring finger protein
ZNF23 zinc finger protein 23
ZNF324 zinc finger protein 324
ZNF668 zinc finger protein 668
ZSWIM1 zinc finger, SWIM-type containing 1