HOS Gene Set

Dataset CCLE Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

349 genes with high or low expression in HOS relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
FAM217A family with sequence similarity 217, member A 3.40798
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G 3.40596
KMT2A lysine (K)-specific methyltransferase 2A 3.17326
MRPL9 mitochondrial ribosomal protein L9 3.06052
ICE1 interactor of little elongation complex ELL subunit 1 2.94534
MUT methylmalonyl CoA mutase 2.94035
UBAP2L ubiquitin associated protein 2-like 2.88454
FOXR1 forkhead box R1 2.62036
SNAPIN SNAP-associated protein 2.6102
INTS3 integrator complex subunit 3 2.59517
ILF2 interleukin enhancer binding factor 2 2.57742
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 2.54351
SMC5 structural maintenance of chromosomes 5 2.47544
EIF4E2 eukaryotic translation initiation factor 4E family member 2 2.46883
UBE4A ubiquitination factor E4A 2.45412
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33 2.43839
LOC100652768 uncharacterized LOC100652768 2.41242
SRF serum response factor (c-fos serum response element-binding transcription factor) 2.38002
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 2.32605
TIGD1 tigger transposable element derived 1 2.28282
PGM2 phosphoglucomutase 2 2.25284
LOC100288637 OTU deubiquitinase 7A pseudogene 2.24588
THOC1 THO complex 1 2.22492
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) 2.20362
MRPS21 mitochondrial ribosomal protein S21 2.1966
CENPQ centromere protein Q 2.17557
TMEM88 transmembrane protein 88 2.12599
DEK DEK proto-oncogene 2.09861
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 2.05419
LRR1 leucine rich repeat protein 1 2.0527
TMEM136 transmembrane protein 136 2.05179
ZNF876P zinc finger protein 876, pseudogene 2.04169
NPPB natriuretic peptide B 2.04044
EIF3J eukaryotic translation initiation factor 3, subunit J 2.02581
PFAS phosphoribosylformylglycinamidine synthase 2.0131
MYH10 myosin, heavy chain 10, non-muscle 2.00958
WSB1 WD repeat and SOCS box containing 1 2.00171
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 1.98358
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1 1.96896
GEMIN4 gem (nuclear organelle) associated protein 4 1.96317
MUS81 MUS81 structure-specific endonuclease subunit 1.96002
DROSHA drosha, ribonuclease type III 1.96001
TRAPPC4 trafficking protein particle complex 4 1.95999
NBPF3 neuroblastoma breakpoint family, member 3 1.95684
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 1.94995
SKA3 spindle and kinetochore associated complex subunit 3 1.92898
DBF4B DBF4 zinc finger B 1.91535
SCO1 SCO1 cytochrome c oxidase assembly protein 1.91507
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) 1.90941
MYL12B myosin, light chain 12B, regulatory 1.87778
USP9X ubiquitin specific peptidase 9, X-linked 1.87565
NDC80 NDC80 kinetochore complex component 1.87362
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa 1.86991
STK25 serine/threonine kinase 25 1.8538
PDHB pyruvate dehydrogenase (lipoamide) beta 1.8536
DTYMK deoxythymidylate kinase (thymidylate kinase) 1.85056
DCAF4 DDB1 and CUL4 associated factor 4 1.85032
SNHG3 small nucleolar RNA host gene 3 1.8414
HAUS2 HAUS augmin-like complex, subunit 2 1.83786
SSB Sjogren syndrome antigen B (autoantigen La) 1.83714
BRIX1 BRX1, biogenesis of ribosomes 1.83388
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 1.83271
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 1.82634
MRPL11 mitochondrial ribosomal protein L11 1.8178
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.81697
TPM3 tropomyosin 3 1.81559
METTL15 methyltransferase like 15 1.81266
ZC3H14 zinc finger CCCH-type containing 14 1.81126
ZNF843 zinc finger protein 843 1.80543
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 1.80361
AMPH amphiphysin 1.79231
CIDEA cell death-inducing DFFA-like effector a 1.78252
PRPF3 pre-mRNA processing factor 3 1.7678
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 1.76509
FERMT2 fermitin family member 2 1.7647
ADAM33 ADAM metallopeptidase domain 33 1.76467
NPY neuropeptide Y 1.75887
MED31 mediator complex subunit 31 1.75814
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 1.75562
MIS12 MIS12 kinetochore complex component 1.75281
FOXE3 forkhead box E3 1.74623
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 1.7458
RNF214 ring finger protein 214 1.74081
TNN tenascin N 1.73437
NUP88 nucleoporin 88kDa 1.72274
COLCA1 colorectal cancer associated 1 1.72212
HSPA8 heat shock 70kDa protein 8 1.71716
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 1.71688
CDK7 cyclin-dependent kinase 7 1.71414
RTP3 receptor (chemosensory) transporter protein 3 1.71281
GSC goosecoid homeobox 1.69922
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 1.69876
C17ORF104 chromosome 17 open reading frame 104 1.69653
NPAS4 neuronal PAS domain protein 4 1.69175
ACAT2 acetyl-CoA acetyltransferase 2 1.67976
RPE ribulose-5-phosphate-3-epimerase 1.67317
RPA1 replication protein A1, 70kDa 1.6716
ZNF770 zinc finger protein 770 1.66997
NUCLEOLIN nucleolin multifunctional protein 1.66952
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 1.66268
ZAR1 zygote arrest 1 1.66077
ZNF641 zinc finger protein 641 1.64921
PANK3 pantothenate kinase 3 1.64747
KNSTRN kinetochore-localized astrin/SPAG5 binding protein 1.63799
RABGGTB Rab geranylgeranyltransferase, beta subunit 1.63669
TEX10 testis expressed 10 1.63141
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 1.62573
TDRKH tudor and KH domain containing 1.62253
SLAIN2 SLAIN motif family, member 2 1.62225
TCF15 transcription factor 15 (basic helix-loop-helix) 1.61292
TUFT1 tuftelin 1 1.60647
XPO5 exportin 5 1.60578
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 1.60347
OTUD7B OTU deubiquitinase 7B 1.59517
PALM2 paralemmin 2 1.59319
ENOSF1 enolase superfamily member 1 1.59313
FASTKD3 FAST kinase domains 3 1.59166
CHTOP chromatin target of PRMT1 1.5894
CEP78 centrosomal protein 78kDa 1.57978
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 1.57661
ELAC2 elaC ribonuclease Z 2 1.56745
HAX1 HCLS1 associated protein X-1 1.56704
KIAA0368 KIAA0368 1.56467
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 1.56223
AIF1L allograft inflammatory factor 1-like 1.55763
MICA MHC class I polypeptide-related sequence A 1.55706
SLC10A4 solute carrier family 10, member 4 1.55323
B3GNT1 1.54034
CEP164 centrosomal protein 164kDa 1.53889
CLUH clustered mitochondria (cluA/CLU1) homolog 1.53235
AASS aminoadipate-semialdehyde synthase 1.53
TRPC6 transient receptor potential cation channel, subfamily C, member 6 1.52395
LY6G5B lymphocyte antigen 6 complex, locus G5B 1.52244
SF3B4 splicing factor 3b, subunit 4, 49kDa 1.51706
ZNF687 zinc finger protein 687 1.51461
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 1.50978
NUP155 nucleoporin 155kDa 1.50952
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 1.49941
SCN2B sodium channel, voltage gated, type II beta subunit 1.49859
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 1.49787
FBXL21 F-box and leucine-rich repeat protein 21 (gene/pseudogene) 1.49628
PAX6 paired box 6 1.48582
CASC5 cancer susceptibility candidate 5 1.47528
KIAA0101 KIAA0101 1.47393
CKAP5 cytoskeleton associated protein 5 1.47175
EMILIN2 elastin microfibril interfacer 2 1.46987
CCDC66 coiled-coil domain containing 66 1.46941
EFTUD2 elongation factor Tu GTP binding domain containing 2 1.46813
NUP153 nucleoporin 153kDa 1.46806
MOCS1 molybdenum cofactor synthesis 1 1.46749
GLO1 glyoxalase I 1.46669
RNF20 ring finger protein 20, E3 ubiquitin protein ligase 1.46023
L2HGDH L-2-hydroxyglutarate dehydrogenase 1.46
TLL1 tolloid-like 1 1.44946
EMC6 ER membrane protein complex subunit 6 1.44783
FAM187B family with sequence similarity 187, member B 1.44511
HDLBP high density lipoprotein binding protein 1.44393
RBP7 retinol binding protein 7, cellular 1.44121
RABL6 RAB, member RAS oncogene family-like 6 1.43972
NUP188 nucleoporin 188kDa 1.43778
VCPKMT valosin containing protein lysine (K) methyltransferase 1.4377
TIPIN TIMELESS interacting protein 1.43652
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 1.43579
CCT8 chaperonin containing TCP1, subunit 8 (theta) 1.43171
LY6K lymphocyte antigen 6 complex, locus K 1.43109
CAPN10 calpain 10 1.42584
C1ORF43 chromosome 1 open reading frame 43 1.41978
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 1.41272
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 1.41014
FAM189A1 family with sequence similarity 189, member A1 1.40915
KLHL17 kelch-like family member 17 1.4065
BEST2 bestrophin 2 1.4049
KIF23 kinesin family member 23 1.40488
WDR75 WD repeat domain 75 1.40319
BRMS1 breast cancer metastasis suppressor 1 1.40302
COMMD8 COMM domain containing 8 1.40144
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 1.401
CCDC148 coiled-coil domain containing 148 1.39989
QRFPR pyroglutamylated RFamide peptide receptor 1.39737
IARS isoleucyl-tRNA synthetase 1.39637
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 1.39582
PAPOLB poly(A) polymerase beta (testis specific) 1.39538
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 1.39264
LYSMD1 LysM, putative peptidoglycan-binding, domain containing 1 1.39116
DPP8 dipeptidyl-peptidase 8 1.38465
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like 1.38168
SPDL1 spindle apparatus coiled-coil protein 1 1.38026
RP2 retinitis pigmentosa 2 (X-linked recessive) 1.3801
MEIOB meiosis specific with OB domains 1.37945
PHF5A PHD finger protein 5A 1.37369
MRPL21 mitochondrial ribosomal protein L21 1.37227
MAMDC2 MAM domain containing 2 1.3714
GATAD2B GATA zinc finger domain containing 2B 1.3708
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit 1.36927
LOC145474 uncharacterized LOC145474 1.36772
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 1.35812
CEP76 centrosomal protein 76kDa 1.35755
ANKRD33B ankyrin repeat domain 33B 1.35564
TARS threonyl-tRNA synthetase 1.35122
SOX3 SRY (sex determining region Y)-box 3 1.35039
CYB5D1 cytochrome b5 domain containing 1 1.34877

low expression

Symbol Name Standardized Value
ADAM17 ADAM metallopeptidase domain 17 -3.07217
IPMK inositol polyphosphate multikinase -3.0712
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 -2.99384
SCAMP3 secretory carrier membrane protein 3 -2.87459
SLC39A11 solute carrier family 39, member 11 -2.69065
KRTCAP2 keratinocyte associated protein 2 -2.51699
SLC17A2 solute carrier family 17, member 2 -2.46189
PLEKHS1 pleckstrin homology domain containing, family S member 1 -2.43902
SAGE1 sarcoma antigen 1 -2.38076
IL36R interleukin 36 receptor -2.36174
ADAR adenosine deaminase, RNA-specific -2.35622
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -2.35018
LOC644135 uncharacterized LOC644135 -2.32864
FSCN2 fascin actin-bundling protein 2, retinal -2.28237
CD300C CD300c molecule -2.23633
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) -2.22211
C11ORF1 chromosome 11 open reading frame 1 -2.21563
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 -2.19431
POU3F2 POU class 3 homeobox 2 -2.18842
PACRGL PARK2 co-regulated-like -2.17924
TENM1 teneurin transmembrane protein 1 -2.1751
LRRC19 leucine rich repeat containing 19 -2.16952
DCAF8 DDB1 and CUL4 associated factor 8 -2.16881
ZNF793 zinc finger protein 793 -2.14086
CA5A carbonic anhydrase VA, mitochondrial -2.13833
MFSD11 major facilitator superfamily domain containing 11 -2.10616
GOSR1 golgi SNAP receptor complex member 1 -2.10263
FLAD1 flavin adenine dinucleotide synthetase 1 -2.08781
GMIP GEM interacting protein -2.07316
SLC25A53 solute carrier family 25, member 53 -2.06995
C20ORF195 chromosome 20 open reading frame 195 -2.05006
LOC100128288 uncharacterized LOC100128288 -2.02851
CYP4X1 cytochrome P450, family 4, subfamily X, polypeptide 1 -2.0284
UBE3B ubiquitin protein ligase E3B -2.02048
SYT4 synaptotagmin IV -2.01968
CXCR2 chemokine (C-X-C motif) receptor 2 -2.0159
CUL9 cullin 9 -2.01388
LOC653739 -1.99988
DSCR3 Down syndrome critical region 3 -1.98928
LOC339298 uncharacterized LOC339298 -1.96911
GHDC GH3 domain containing -1.95619
RAB28 RAB28, member RAS oncogene family -1.9538
MKRN1 makorin ring finger protein 1 -1.95358
TM9SF4 transmembrane 9 superfamily protein member 4 -1.94622
FLOT2 flotillin 2 -1.93748
CALN1 calneuron 1 -1.93117
C7ORF73 chromosome 7 open reading frame 73 -1.92286
ZNF333 zinc finger protein 333 -1.91524
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -1.89451
PLCH2 phospholipase C, eta 2 -1.8916
LRGUK leucine-rich repeats and guanylate kinase domain containing -1.88715
MAGEB6 melanoma antigen family B6 -1.87877
NUB1 negative regulator of ubiquitin-like proteins 1 -1.86747
ZC3HAV1L zinc finger CCCH-type, antiviral 1-like -1.86716
RNF103 ring finger protein 103 -1.86435
EDDM3B epididymal protein 3B -1.86329
ZC3H6 zinc finger CCCH-type containing 6 -1.86255
CRLF3 cytokine receptor-like factor 3 -1.84204
GRM1 glutamate receptor, metabotropic 1 -1.83616
MLN motilin -1.80849
ZNF557 zinc finger protein 557 -1.80738
CLK2 CDC-like kinase 2 -1.80107
FAM222B family with sequence similarity 222, member B -1.77629
DRD4 dopamine receptor D4 -1.77491
ITFG1 integrin alpha FG-GAP repeat containing 1 -1.77209
BPIFA3 BPI fold containing family A, member 3 -1.77149
HIBADH 3-hydroxyisobutyrate dehydrogenase -1.76892
ZNF746 zinc finger protein 746 -1.76741
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 -1.76623
LINC00208 long intergenic non-protein coding RNA 208 -1.76118
ZNF786 zinc finger protein 786 -1.74886
IRAK4 interleukin-1 receptor-associated kinase 4 -1.74446
FASTK Fas-activated serine/threonine kinase -1.74097
PDE3A phosphodiesterase 3A, cGMP-inhibited -1.74035
CNOT4 CCR4-NOT transcription complex, subunit 4 -1.73907
FGF8 fibroblast growth factor 8 (androgen-induced) -1.73347
PYGO2 pygopus family PHD finger 2 -1.72425
PP12613 uncharacterized LOC100192379 -1.70943
LMBRD1 LMBR1 domain containing 1 -1.69881
MEOX1 mesenchyme homeobox 1 -1.6971
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -1.69468
S100A8 S100 calcium binding protein A8 -1.68813
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 -1.68807
LRRC29 leucine rich repeat containing 29 -1.67239
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide -1.67066
NKAIN2 Na+/K+ transporting ATPase interacting 2 -1.6674
KRT6A keratin 6A, type II -1.66274
LINC00311 long intergenic non-protein coding RNA 311 -1.64668
PROX1-AS1 PROX1 antisense RNA 1 -1.63002
FSIP2 fibrous sheath interacting protein 2 -1.63
CRELD1 cysteine-rich with EGF-like domains 1 -1.6209
CCDC125 coiled-coil domain containing 125 -1.61521
IL22 interleukin 22 -1.60929
GSTK1 glutathione S-transferase kappa 1 -1.60661
C5ORF47 chromosome 5 open reading frame 47 -1.60446
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 -1.60201
ARHGAP15 Rho GTPase activating protein 15 -1.59858
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3 -1.59606
RIT1 Ras-like without CAAX 1 -1.59597
PMVK phosphomevalonate kinase -1.59067
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 -1.58045
LMO2 LIM domain only 2 (rhombotin-like 1) -1.57626
B3GAT3 beta-1,3-glucuronyltransferase 3 -1.572
S100Z S100 calcium binding protein Z -1.56792
FAM81B family with sequence similarity 81, member B -1.56659
EREG epiregulin -1.56634
TMEM59 transmembrane protein 59 -1.56217
ELANE elastase, neutrophil expressed -1.56096
CYHR1 cysteine/histidine-rich 1 -1.55657
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -1.5528
DEFB1 defensin, beta 1 -1.54701
TP53TG1 TP53 target 1 (non-protein coding) -1.54629
TBX19 T-box 19 -1.54408
UCN urocortin -1.54036
LDHAL6B lactate dehydrogenase A-like 6B -1.5397
BCL7B B-cell CLL/lymphoma 7B -1.53769
DHRS1 dehydrogenase/reductase (SDR family) member 1 -1.52926
KIDINS220 kinase D-interacting substrate, 220kDa -1.52685
PRB1 proline-rich protein BstNI subfamily 1 -1.52305
ZNF282 zinc finger protein 282 -1.52138
TESK1 testis-specific kinase 1 -1.51977
CT83 cancer/testis antigen 83 -1.51911
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -1.51361
SSH2 slingshot protein phosphatase 2 -1.51224
CCDC115 coiled-coil domain containing 115 -1.509
MGP matrix Gla protein -1.50873
PSG1 pregnancy specific beta-1-glycoprotein 1 -1.50729
ATRAID all-trans retinoic acid-induced differentiation factor -1.50521
LHCGR luteinizing hormone/choriogonadotropin receptor -1.49959
FCRL1 Fc receptor-like 1 -1.49784
PARP9 poly (ADP-ribose) polymerase family, member 9 -1.49217
SCRT1 scratch family zinc finger 1 -1.48939
TOLLIP toll interacting protein -1.48884
PDIA4 protein disulfide isomerase family A, member 4 -1.48779
DPT dermatopontin -1.47847
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator -1.47739
MFSD4 major facilitator superfamily domain containing 4 -1.47501
FGF10 fibroblast growth factor 10 -1.47322
PROX2 prospero homeobox 2 -1.47002
TRAV8-1 T cell receptor alpha variable 8-1 -1.4689
SCP2 sterol carrier protein 2 -1.4655
PICK1 protein interacting with PRKCA 1 -1.46509
SHARPIN SHANK-associated RH domain interactor -1.46472
CALR3 calreticulin 3 -1.46367
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -1.45688
ADCK5 aarF domain containing kinase 5 -1.45673
ZNF212 zinc finger protein 212 -1.45551
FAM134C family with sequence similarity 134, member C -1.4521