HOS Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
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Genes

313 genes with high or low copy number in HOS relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
LGALS9 lectin, galactoside-binding, soluble, 9 3.12177
LYRM9 LYR motif containing 9 2.93899
MUT methylmalonyl CoA mutase 2.93899
GLYATL3 glycine-N-acyltransferase-like 3 2.93899
CENPQ centromere protein Q 2.93899
NOS2 nitric oxide synthase 2, inducible 2.76305
CD248 CD248 molecule, endosialin 2.49065
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 2.49065
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 2.49065
KLC2 kinesin light chain 2 2.49065
RIN1 Ras and Rab interactor 1 2.49065
CNIH2 cornichon family AMPA receptor auxiliary protein 2 2.49065
PACS1 phosphofurin acidic cluster sorting protein 1 2.49065
NPAS4 neuronal PAS domain protein 4 2.49065
TMEM151A transmembrane protein 151A 2.49065
B3GNT1 2.49065
BRMS1 breast cancer metastasis suppressor 1 2.49065
RAB1B RAB1B, member RAS oncogene family 2.49065
RBM14 RNA binding motif protein 14 2.44392
CTSF cathepsin F 2.44392
ZDHHC24 zinc finger, DHHC-type containing 24 2.44392
MRPL11 mitochondrial ribosomal protein L11 2.44392
BBS1 Bardet-Biedl syndrome 1 2.44392
PELI3 pellino E3 ubiquitin protein ligase family member 3 2.44392
ACTN3 actinin, alpha 3 (gene/pseudogene) 2.44392
CCS copper chaperone for superoxide dismutase 2.44392
CCDC87 coiled-coil domain containing 87 2.44392
SPTBN2 spectrin, beta, non-erythrocytic 2 2.41451
RBM4B RNA binding motif protein 4B 2.41451
DPP3 dipeptidyl-peptidase 3 2.41451
RBM14-RBM4 RBM14-RBM4 readthrough 2.41451
RBM4 RNA binding motif protein 4 2.41451
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.39327
MIR4691 microRNA 4691 2.39327
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 2.39327
RHOD ras homolog family member D 2.39327
C11ORF86 chromosome 11 open reading frame 86 2.39327
C11ORF80 chromosome 11 open reading frame 80 2.39327
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 2.39327
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 2.39327
SYT12 synaptotagmin XII 2.39327
RCE1 Ras converting CAAX endopeptidase 1 2.39327
PC pyruvate carboxylase 2.39327
UNC93B1 unc-93 homolog B1 (C. elegans) 2.36889
CLCF1 cardiotrophin-like cytokine factor 1 2.36889
C11ORF24 chromosome 11 open reading frame 24 2.36889
TBC1D10C TBC1 domain family, member 10C 2.36889
RAD9A RAD9 homolog A (S. pombe) 2.36889
ANKRD13D ankyrin repeat domain 13 family, member D 2.36889
LOC100130987 uncharacterized LOC100130987 2.36889
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.36889
ADRBK1 adrenergic, beta, receptor kinase 1 2.36889
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 2.36889
SSH3 slingshot protein phosphatase 3 2.36889
CHKA choline kinase alpha 2.36889
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 2.36889
IL6R interleukin 6 receptor 2.35236
CORO1B coronin, actin binding protein, 1B 2.35236
CABP2 calcium binding protein 2 2.35236
CRCT1 cysteine-rich C-terminal 1 2.35236
CARNS1 carnosine synthase 1 2.35236
TBX10 T-box 10 2.35236
CABP4 calcium binding protein 4 2.35236
AIP aryl hydrocarbon receptor interacting protein 2.35236
NUDT8 nudix (nucleoside diphosphate linked moiety X)-type motif 8 2.35236
ACY3 aminoacylase 3 2.35236
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) 2.35236
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 2.35236
CRNN cornulin 2.35236
LCE5A late cornified envelope 5A 2.35236
DOC2GP double C2-like domains, gamma, pseudogene 2.35236
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 2.35236
GPR152 G protein-coupled receptor 152 2.35236
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 2.35236
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein 2.35236
TMEM134 transmembrane protein 134 2.35236
KDM2A lysine (K)-specific demethylase 2A 2.35236
FLG2 filaggrin family member 2 2.3178
LRP5 low density lipoprotein receptor-related protein 5 2.3178
FLG filaggrin 2.3178
LCE1F late cornified envelope 1F 2.3178
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2 2.3178
AQP10 aquaporin 10 2.3178
S100A10 S100 calcium binding protein A10 2.3178
S100A11 S100 calcium binding protein A11 2.3178
C11ORF72 chromosome 11 open reading frame 72 2.3178
LCE6A late cornified envelope 6A 2.3178
LCE3A late cornified envelope 3A 2.3178
LCE3E late cornified envelope 3E 2.3178
HAX1 HCLS1 associated protein X-1 2.3178
GSTP1 glutathione S-transferase pi 1 2.3178
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 2.3178
SPRR1B small proline-rich protein 1B 2.30944
SPRR1A small proline-rich protein 1A 2.30944
TDRKH tudor and KH domain containing 2.30944
TPM3 tropomyosin 3 2.30944
C2CD4D C2 calcium-dependent domain containing 4D 2.30944
C1ORF68 chromosome 1 open reading frame 68 2.30944
IVL involucrin 2.30944
OAZ3 ornithine decarboxylase antizyme 3 2.30944
TCHHL1 trichohyalin-like 1 2.30944
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 2.30944
LCE4A late cornified envelope 4A 2.30944
LCE3D late cornified envelope 3D 2.30944
SPRR2D small proline-rich protein 2D 2.30944
SMCP sperm mitochondria-associated cysteine-rich protein 2.30944
KPRP keratinocyte proline-rich protein 2.30944
MRPL9 mitochondrial ribosomal protein L9 2.30944
LOC100132111 uncharacterized LOC100132111 2.30944
SNX27 sorting nexin family member 27 2.30944
SPRR3 small proline-rich protein 3 2.30944
LCE1A late cornified envelope 1A 2.30944
LCE1C late cornified envelope 1C 2.30944
LCE1B late cornified envelope 1B 2.30944
CELF3 CUGBP, Elav-like family member 3 2.30944
RPTN repetin 2.30944
TCHH trichohyalin 2.30944
MIR190B microRNA 190b 2.30944
C1ORF189 chromosome 1 open reading frame 189 2.30944
LINGO4 leucine rich repeat and Ig domain containing 4 2.30944
LCE2A late cornified envelope 2A 2.30944
UBAP2L ubiquitin associated protein 2-like 2.30944
THEM5 thioesterase superfamily member 5 2.30944
C1ORF43 chromosome 1 open reading frame 43 2.30944
THEM4 thioesterase superfamily member 4 2.30944
LCE2C late cornified envelope 2C 2.30944
RORC RAR-related orphan receptor C 2.30944
LCE2B late cornified envelope 2B 2.30944
LCE2D late cornified envelope 2D 2.30944
HIST2H2AB histone cluster 2, H2ab 2.283
NUP210L nucleoporin 210kDa-like 2.283
INTS3 integrator complex subunit 3 2.283
PRR9 proline rich 9 2.283
SPRR2F small proline-rich protein 2F 2.283
RPS27 ribosomal protein S27 2.283
SPRR2G small proline-rich protein 2G 2.283
MTMR11 myotubularin related protein 11 2.283
SF3B4 splicing factor 3b, subunit 4, 49kDa 2.283
HIST2H2AC histone cluster 2, H2ac 2.283
LELP1 late cornified envelope-like proline-rich 1 2.283
HIST2H2BE histone cluster 2, H2be 2.283
SPRR2C small proline-rich protein 2C (pseudogene) 2.283
CREB3L4 cAMP responsive element binding protein 3-like 4 2.283
RAB13 RAB13, member RAS oncogene family 2.283
DENND4B DENN/MADD domain containing 4B 2.283
SPRR4 small proline-rich protein 4 2.283
SLC39A1 solute carrier family 39 (zinc transporter), member 1 2.283
LOR loricrin 2.283
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.283
CRTC2 CREB regulated transcription coactivator 2 2.283
OTUD7B OTU deubiquitinase 7B 2.283
SV2A synaptic vesicle glycoprotein 2A 2.283
JTB jumping translocation breakpoint 2.283
SPRR2B small proline-rich protein 2B 2.283
HRNR hornerin 2.283
GATAD2B GATA zinc finger domain containing 2B 2.283
BOLA1 bolA family member 1 2.283
SPRR2E small proline-rich protein 2E 2.283
PGLYRP4 peptidoglycan recognition protein 4 2.26395
S100A7A S100 calcium binding protein A7A 2.26395
PGLYRP3 peptidoglycan recognition protein 3 2.26395
S100A7L2 S100 calcium binding protein A7-like 2 2.26395
SNORA58 small nucleolar RNA, H/ACA box 58 2.26395
NPR1 natriuretic peptide receptor 1 2.26395
S100A16 S100 calcium binding protein A16 2.26395
S100A4 S100 calcium binding protein A4 2.26395
CHTOP chromatin target of PRMT1 2.26395
S100A14 S100 calcium binding protein A14 2.26395
S100A12 S100 calcium binding protein A12 2.26395
ILF2 interleukin enhancer binding factor 2 2.26395
S100A2 S100 calcium binding protein A2 2.26395
S100A9 S100 calcium binding protein A9 2.26395
S100A7 S100 calcium binding protein A7 2.26395
S100A13 S100 calcium binding protein A13 2.26395
S100A6 S100 calcium binding protein A6 2.26395
S100A1 S100 calcium binding protein A1 2.26395
S100A3 S100 calcium binding protein A3 2.26395
SPRR2A small proline-rich protein 2A 2.26395
SNAPIN SNAP-associated protein 2.26395
S100A5 S100 calcium binding protein A5 2.26395
S100A8 S100 calcium binding protein A8 2.26395
CGN cingulin 2.25904
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 2.25904
MIR554 microRNA 554 2.25904
GAL galanin/GMAP prepropeptide 2.25904
TUFT1 tuftelin 1 2.25904
PLEKHO1 pleckstrin homology domain containing, family O member 1 2.25904
APH1A APH1A gamma secretase subunit 2.25904
C1ORF54 chromosome 1 open reading frame 54 2.25904
CA14 carbonic anhydrase XIV 2.25904
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 2.25904
PRPF3 pre-mRNA processing factor 3 2.24845
MTL5 metallothionein-like 5, testis-specific (tesmin) 2.24845
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.24845
MRPS21 mitochondrial ribosomal protein S21 2.24845
SELENBP1 selenium binding protein 1 2.24845
LYSMD1 LysM, putative peptidoglycan-binding, domain containing 1 2.24845
SCNM1 sodium channel modifier 1 2.24845
TIPE2 TNF alpha induced protein 8 like 2 2.24845
TNFAIP8L2-SCNM1 TNFAIP8L2-SCNM1 readthrough 2.24845
CERS2 ceramide synthase 2 2.24139
POGZ pogo transposable element with ZNF domain 2.24139
C1ORF56 chromosome 1 open reading frame 56 2.24139
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 2.24139
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.24139
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 2.24139
SETDB1 SET domain, bifurcated 1 2.24139
ZNF687 zinc finger protein 687 2.24139
CPT1A carnitine palmitoyltransferase 1A (liver) 2.24139
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 2.24139
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 2.24139
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 2.24139
CDC42SE1 CDC42 small effector 1 2.24139
TMOD4 tropomodulin 4 (muscle) 2.24139
GABPB2 GA binding protein transcription factor, beta subunit 2 2.24139
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 2.24139
PRUNE prune exopolyphosphatase 2.2355
BNIPL BCL2/adenovirus E1B 19kD interacting protein like 2.2355
ANXA9 annexin A9 2.2355
FAM63A family with sequence similarity 63, member A 2.2355
ARNT aryl hydrocarbon receptor nuclear translocator 2.23324
RPRD2 regulation of nuclear pre-mRNA domain containing 2 2.23324
CTSS cathepsin S 2.23078
GOLPH3L golgi phosphoprotein 3-like 2.23078
ENSA endosulfine alpha 2.23078
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 2.23078
ECM1 extracellular matrix protein 1 2.23078
CTSK cathepsin K 2.23078
FALEC focally amplified long non-coding RNA in epithelial cancer 2.23078
MRPL21 mitochondrial ribosomal protein L21 2.23078
HORMAD1 HORMA domain containing 1 2.23078
IGHMBP2 immunoglobulin mu binding protein 2 2.23078
MIR4257 microRNA 4257 2.22917
MCL1 myeloid cell leukemia 1 2.22917
ADAMTSL4 ADAMTS-like 4 2.22917
MRGPRD MAS-related GPR, member D 2.22783
MRGPRF MAS-related GPR, member F 2.22633
DOK5 docking protein 5 2.22633
TSHZ2 teashirt zinc finger homeobox 2 2.22558
MIR4756 microRNA 4756 2.22558
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 2.22558
BCAS1 breast carcinoma amplified sequence 1 2.22291
PFDN4 prefoldin subunit 4 2.22291
SUMO1P1 SUMO1 pseudogene 1 2.22291
ZNF217 zinc finger protein 217 2.22291
TPCN2 two pore segment channel 2 2.21258
FADD Fas (TNFRSF6)-associated via death domain 2.16564
MIR548K microRNA 548k 2.16564
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 2.16459
MYEOV myeloma overexpressed 2.16459
LOC340107 uncharacterized LOC340107 2.16307
CTTN cortactin 2.16307
FGF3 fibroblast growth factor 3 2.16307
ANO1 anoctamin 1, calcium activated chloride channel 2.16307
FGF4 fibroblast growth factor 4 2.16176
CCND1 cyclin D1 2.1605
FGF19 fibroblast growth factor 19 2.1605
ORAOV1 oral cancer overexpressed 1 2.16017
TMEM136 transmembrane protein 136 2.14116
GRIK4 glutamate receptor, ionotropic, kainate 4 2.14116
CD3D CD3d molecule, delta (CD3-TCR complex) 2.14116
BSX brain-specific homeobox 2.14116
CD3G CD3g molecule, gamma (CD3-TCR complex) 2.14116
GRAMD1B GRAM domain containing 1B 2.14116
POU2F3 POU class 2 homeobox 3 2.14116
CD3E CD3e molecule, epsilon (CD3-TCR complex) 2.14116
SCN4B sodium channel, voltage gated, type IV beta subunit 2.14116
HSPA8 heat shock 70kDa protein 8 2.14116
TMPRSS4 transmembrane protease, serine 4 2.14116
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 2.14116
MPZL3 myelin protein zero-like 3 2.14116
TMPRSS4-AS1 TMPRSS4 antisense RNA 1 2.14116
MIR100HG mir-100-let-7a-2 cluster host gene 2.14116
SCN2B sodium channel, voltage gated, type II beta subunit 2.14116
MPZL2 myelin protein zero-like 2 2.14116
SCN3B sodium channel, voltage gated, type III beta subunit 2.14116
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G 2.14116
MIR4493 microRNA 4493 2.14116
UBE4A ubiquitination factor E4A 2.14116
LOC341056 SUMO1 activating enzyme subunit 1 pseudogene 2.14116
AMICA1 adhesion molecule, interacts with CXADR antigen 1 2.14116
CLMP CXADR-like membrane protein 2.14116
LOC649133 uncharacterized LOC649133 2.14116
IL10RA interleukin 10 receptor, alpha 2.14116
UBASH3B ubiquitin associated and SH3 domain containing B 2.12931
LOC100131626 uncharacterized LOC100131626 2.12703
C11ORF63 chromosome 11 open reading frame 63 2.12703
CRTAM cytotoxic and regulatory T cell molecule 2.12703
OAF OAF homolog (Drosophila) 2.12703
KSR1 kinase suppressor of ras 1 2.12703
SIK3 SIK family kinase 3 2.12703
KMT2A lysine (K)-specific methyltransferase 2A 2.12225
WSB1 WD repeat and SOCS box containing 1 2.12225
MIR4522 microRNA 4522 2.12225
TBC1D3P5 TBC1 domain family, member 3 pseudogene 5 2.12225
TTC36 tetratricopeptide repeat domain 36 2.12225
TMEM25 transmembrane protein 25 2.12225
FAM86C2P family with sequence similarity 86, member A pseudogene 2.07822
LCE1E late cornified envelope 1E 2.07574
HIST2H3C histone cluster 2, H3c 2.0752
HIST2H2AA4 histone cluster 2, H2aa4 2.0752
LCE1D late cornified envelope 1D 2.0752
HIST2H2BC histone cluster 2, H2bc (pseudogene) 2.0752
HIST2H4A histone cluster 2, H4a 2.0752
MMP7 matrix metallopeptidase 7 2.06989
PPP6R3 protein phosphatase 6, regulatory subunit 3 2.06989
MMP20 matrix metallopeptidase 20 2.06989
CDH10 cadherin 10, type 2 (T2-cadherin) 2.05014
SHANK2 SH3 and multiple ankyrin repeat domains 2 2.04969

low copy number

Symbol Name Standardized Value
TUSC7 tumor suppressor candidate 7 (non-protein coding) -3.48261
GRIK2 glutamate receptor, ionotropic, kainate 2 -3.05196
LSAMP limbic system-associated membrane protein -2.91612
DIAPH2 diaphanous-related formin 2 -2.82214