HOXA13 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description homeobox A13|In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3209)
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Genes

334 genes differentially expressed following the HOXA13 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SLC26A9 solute carrier family 26 (anion exchanger), member 9 2.886
NME5 NME/NM23 family member 5 2.886
APOA2 apolipoprotein A-II 2.886
C6ORF58 chromosome 6 open reading frame 58 2.886
GFAP glial fibrillary acidic protein 2.886
SIGLEC5 sialic acid binding Ig-like lectin 5 2.886
TLX2 T-cell leukemia homeobox 2 2.886
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 2.886
GPR21 G protein-coupled receptor 21 2.886
ADAD2 adenosine deaminase domain containing 2 2.886
TAL2 T-cell acute lymphocytic leukemia 2 2.886
PTAFR platelet-activating factor receptor 2.886
SLC25A41 solute carrier family 25, member 41 2.886
PI16 peptidase inhibitor 16 2.886
IZUMO3 IZUMO family member 3 2.886
HCRTR1 hypocretin (orexin) receptor 1 2.886
GFRA3 GDNF family receptor alpha 3 2.886
CELA3B chymotrypsin-like elastase family, member 3B 2.886
PCDHB8 protocadherin beta 8 2.886
WNT3A wingless-type MMTV integration site family, member 3A 2.886
SSTR1 somatostatin receptor 1 2.886
CASP5 caspase 5, apoptosis-related cysteine peptidase 2.886
SLC25A43 solute carrier family 25, member 43 2.886
TNIP3 TNFAIP3 interacting protein 3 2.886
C11ORF86 chromosome 11 open reading frame 86 2.886
MUC22 mucin 22 2.886
CRYGN crystallin, gamma N 2.886
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 2.886
GALR3 galanin receptor 3 2.886
LOC105378220 macrophage receptor MARCO-like 2.886
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6 2.886
PRR22 proline rich 22 2.886
HIC1 hypermethylated in cancer 1 2.886
EPHB3 EPH receptor B3 2.886
EMCN endomucin 2.886
RIMBP3C RIMS binding protein 3C 2.886
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 2.886
CA1 carbonic anhydrase I 2.886
STRA8 stimulated by retinoic acid 8 2.886
POSTN periostin, osteoblast specific factor 2.886
RGL4 ral guanine nucleotide dissociation stimulator-like 4 2.886
ARSI arylsulfatase family, member I 2.886
TPSD1 tryptase delta 1 2.886
C1ORF146 chromosome 1 open reading frame 146 2.886
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 2.886
KHDC3L KH domain containing 3-like, subcortical maternal complex member 2.886
OR7A17 olfactory receptor, family 7, subfamily A, member 17 2.886
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 2.886
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 2.886
LOC124906892 uncharacterized LOC124906892 2.886
FRG2C FSHD region gene 2 family, member C 2.886
SPRR2E small proline-rich protein 2E 2.886
CASZ1 castor zinc finger 1 2.886
PDC phosducin 2.886
C1QTNF9B C1q and tumor necrosis factor related protein 9B 2.886
TMEM40 transmembrane protein 40 2.886
MIOX myo-inositol oxygenase 2.886
DOK2 docking protein 2, 56kDa 2.886
LY6K lymphocyte antigen 6 complex, locus K 2.886
KHDC1L KH homology domain containing 1-like 2.886
RHCG Rh family, C glycoprotein 2.886
RHCE Rh blood group, CcEe antigens 2.886
CIMIP2C ciliary microtubule inner protein 2C 2.886
ANKRD42-DT ANKRD42 divergent transcript 2.886
LIPT2-AS1 LIPT2 antisense RNA 1 2.886
H4C12 H4 clustered histone 12 2.886
SERTM2 serine rich and transmembrane domain containing 2 2.886
CCDC187 coiled-coil domain containing 187 2.886
GOLGA6L7 golgin A6 family like 7 2.886
OTOF otoferlin 2.886
ZAR1 zygote arrest 1 2.886
LTB4R2 leukotriene B4 receptor 2 2.886
FAM228A family with sequence similarity 228, member A 2.886
MLANA melan-A 2.886
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 2.886
OR7C1 olfactory receptor, family 7, subfamily C, member 1 2.886
CFAP99 cilia and flagella associated protein 99 2.886
PCDHB11 protocadherin beta 11 2.886
MEP1A meprin A, alpha (PABA peptide hydrolase) 2.886
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7 2.886
CD274 CD274 molecule 2.886
LY86 lymphocyte antigen 86 2.886
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.886
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 2.886
SCRT2 scratch family zinc finger 2 2.886
HAPLN2 hyaluronan and proteoglycan link protein 2 2.886
C4ORF50 chromosome 4 open reading frame 50 2.886
DYNAP dynactin associated protein 2.886
HNF1B HNF1 homeobox B 2.886
GPR132 G protein-coupled receptor 132 2.886
RGS21 regulator of G-protein signaling 21 2.886
CDKN2A cyclin-dependent kinase inhibitor 2A 2.886
FOXI2 forkhead box I2 2.886
MIP major intrinsic protein of lens fiber 2.886
SCIMP SLP adaptor and CSK interacting membrane protein 2.886
CFC1B cripto, FRL-1, cryptic family 1B 2.886
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta 2.886
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 2.886
PRM1 protamine 1 2.886
CPA2 carboxypeptidase A2 (pancreatic) 2.886
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 2.886
CDH10 cadherin 10, type 2 (T2-cadherin) 2.886
PAGE4 P antigen family, member 4 (prostate associated) 2.886
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 2.886
PCDHGA3 protocadherin gamma subfamily A, 3 2.886
BAHCC1 BAH domain and coiled-coil containing 1 2.886
FOXE3 forkhead box E3 2.886
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 2.886
CYSLTR1 cysteinyl leukotriene receptor 1 2.886
ANKRD61 ankyrin repeat domain 61 2.886
CPO carboxypeptidase O 2.886
AKR1B15 aldo-keto reductase family 1, member B15 2.886
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 2.886
DNAH12 dynein, axonemal, heavy chain 12 2.886
POF1B premature ovarian failure, 1B 2.886
DQX1 DEAQ box RNA-dependent ATPase 1 2.886
THTPA thiamine triphosphatase 2.886
AQP7 aquaporin 7 2.886
CRYBB3 crystallin, beta B3 2.886
MUC17 mucin 17, cell surface associated 2.886
RRH retinal pigment epithelium-derived rhodopsin homolog 2.886
ISLR immunoglobulin superfamily containing leucine-rich repeat 2.886
ARHGAP40 Rho GTPase activating protein 40 2.886
MEPE matrix extracellular phosphoglycoprotein 2.886
ADAM12 ADAM metallopeptidase domain 12 2.886
ACSS1 acyl-CoA synthetase short-chain family member 1 2.886
TEX29 testis expressed 29 2.886
MB myoglobin 2.886
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 2.886
BHLHA15 basic helix-loop-helix family, member a15 2.886
LRRC24 leucine rich repeat containing 24 2.886
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 2.886
ZFHX4 zinc finger homeobox 4 2.886
QRFP pyroglutamylated RFamide peptide 2.886
CATIP ciliogenesis associated TTC17 interacting protein 2.886
TEX12 testis expressed 12 2.886
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 2.886
RBM24 RNA binding motif protein 24 2.886
ANKRD53 ankyrin repeat domain 53 2.886
PDCD1LG2 programmed cell death 1 ligand 2 2.886
LYZ lysozyme 2.886
NT5C1B 5'-nucleotidase, cytosolic IB 2.886
CTSS cathepsin S 2.886
ITGAD integrin, alpha D 2.886
ZMYND10 zinc finger, MYND-type containing 10 2.886
PRSS21 protease, serine, 21 (testisin) 2.886
TEX38 testis expressed 38 2.886
ST18 suppression of tumorigenicity 18, zinc finger 2.886
RGPD5 RANBP2-like and GRIP domain containing 5 2.886
TAS2R43 taste receptor, type 2, member 43 2.886
TXK TXK tyrosine kinase 2.886
ZC3HAV1L zinc finger CCCH-type, antiviral 1-like 2.886
IL37 interleukin 37 2.886
CDCP2 CUB domain containing protein 2 2.886
PAX5 paired box 5 2.886
ASCL5 achaete-scute family bHLH transcription factor 5 2.886
GLB1L galactosidase, beta 1-like 2.886
DCST2 DC-STAMP domain containing 2 2.886
ANKRD30A ankyrin repeat domain 30A 2.886
R3HDML R3H domain containing-like 2.886
SPDEF SAM pointed domain containing ETS transcription factor 2.886
SOST sclerostin 2.886
METTL21C methyltransferase like 21C 2.886
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 2.886
AGBL1 ATP/GTP binding protein-like 1 2.886
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 2.886
EPN3 epsin 3 2.886
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1 2.886
CARD6 caspase recruitment domain family, member 6 2.886
TBC1D26 TBC1 domain family, member 26 2.886
LST1 leukocyte specific transcript 1 2.886
BTBD18 BTB (POZ) domain containing 18 2.886
ITPKA inositol-trisphosphate 3-kinase A 2.886
TICAM1 toll-like receptor adaptor molecule 1 2.886
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 2.886
ZIC1 Zic family member 1 2.80563
CCP110 centriolar coiled coil protein 110kDa 2.77511
PPP1R37 protein phosphatase 1, regulatory subunit 37 2.73327
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 2.73327
GTF2I general transcription factor IIi 2.70362
DOLK dolichol kinase 2.6868
AIM2 absent in melanoma 2 2.66487
STK16 serine/threonine kinase 16 2.61837
CKAP4 cytoskeleton-associated protein 4 2.55116
WLS wntless Wnt ligand secretion mediator 2.52964
PWP1 PWP1 homolog (S. cerevisiae) 2.48268
GSG1 germ cell associated 1 2.46342
CA7 carbonic anhydrase VII 2.46326
ACRBP acrosin binding protein 2.46326
PNMA8C PNMA family member 8C 2.46326
TGFB3 transforming growth factor, beta 3 2.46326
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) 2.46326
TSPAN8 tetraspanin 8 2.46326
KXD1 KxDL motif containing 1 2.41869
OTUD6A OTU deubiquitinase 6A 2.4034
SNX14 sorting nexin 14 2.37152
NMBR neuromedin B receptor 2.37046
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 2.35732
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 2.34053
MSH4 mutS homolog 4 2.32335
VPS13B vacuolar protein sorting 13 homolog B (yeast) 2.31004
RPS16 ribosomal protein S16 2.30898
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 2.29961
TPRG1L tumor protein p63 regulated 1-like 2.29684
PSME3IP1 proteasome activator subunit 3 interacting protein 1 2.2959
SPRING1 SREBF pathway regulator in golgi 1 2.25142
IRAG1 inositol 1,4,5-triphosphate receptor associated 1 2.20528
CFAP70 cilia and flagella associated protein 70 2.20476
ANXA6 annexin A6 2.17972
MOB1B MOB kinase activator 1B 2.15685
HEATR5A HEAT repeat containing 5A 2.14482
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 2.09169
MED8 mediator complex subunit 8 2.0852
FBXO38 F-box protein 38 2.08093
ISOC1 isochorismatase domain containing 1 2.08093
RASAL1 RAS protein activator like 1 (GAP1 like) 2.06666
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 2.05433
ZNF180 zinc finger protein 180 2.05269
DYNLRB1 dynein, light chain, roadblock-type 1 2.04482
MARCHF5 membrane associated ring-CH-type finger 5 2.03354
CCDC80 coiled-coil domain containing 80 2.0272
SLC35E1 solute carrier family 35, member E1 2.01652
MAP10 microtubule-associated protein 10 2.01562
METTL5 methyltransferase like 5 2.01562

decreased expression

Symbol Name Standardized Value
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -2.886
TUSC1 tumor suppressor candidate 1 -2.886
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -2.886
TCP11L2 t-complex 11, testis-specific-like 2 -2.886
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 -2.886
UCMA upper zone of growth plate and cartilage matrix associated -2.886
LOC107985101 uncharacterized LOC107985101 -2.886
ENGASE endo-beta-N-acetylglucosaminidase -2.886
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -2.886
FLT3LG fms-related tyrosine kinase 3 ligand -2.886
MEX3B mex-3 RNA binding family member B -2.886
PCDHGB1 protocadherin gamma subfamily B, 1 -2.87221
CSMD3 CUB and Sushi multiple domains 3 -2.87221
ACTR3C ARP3 actin-related protein 3 homolog C (yeast) -2.87221
ASB14 ankyrin repeat and SOCS box containing 14 -2.87221
RHOV ras homolog family member V -2.87221
RTP1 receptor (chemosensory) transporter protein 1 -2.87221
VCX variable charge, X-linked -2.87221
OXT oxytocin/neurophysin I prepropeptide -2.87221
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled -2.87221
GNRHR gonadotropin-releasing hormone receptor -2.87221
LONRF2 LON peptidase N-terminal domain and ring finger 2 -2.87221
HIGD1B HIG1 hypoxia inducible domain family, member 1B -2.87221
THPO thrombopoietin -2.87221
LHX1 LIM homeobox 1 -2.87221
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A -2.87221
SPEF2 sperm flagellar 2 -2.87221
SPACA9 sperm acrosome associated 9 -2.87221
TMEM190 transmembrane protein 190 -2.87221
GPHA2 glycoprotein hormone alpha 2 -2.87221
C2CD4D C2 calcium-dependent domain containing 4D -2.87221
FAM107A family with sequence similarity 107, member A -2.87221
CABCOCO1 ciliary associated calcium binding coiled-coil 1 -2.87221
LGALS14 lectin, galactoside-binding, soluble, 14 -2.87221
C17ORF113 chromosome 17 open reading frame 113 -2.87221
LRRC26 leucine rich repeat containing 26 -2.87221
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 -2.87221
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 -2.87221
CXCR2 chemokine (C-X-C motif) receptor 2 -2.87221
ARC activity-regulated cytoskeleton-associated protein -2.87221
TMEM9 transmembrane protein 9 -2.85048
HELB helicase (DNA) B -2.83571
CNTNAP5 contactin associated protein-like 5 -2.82921
KLHL32 kelch-like family member 32 -2.82921
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) -2.75451
WDR6 WD repeat domain 6 -2.75451
FDXACB1 ferredoxin-fold anticodon binding domain containing 1 -2.75211
GIP gastric inhibitory polypeptide -2.75211
MYO18B myosin XVIIIB -2.75211
RARB retinoic acid receptor, beta -2.75211
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 -2.75211
RHBG Rh family, B glycoprotein (gene/pseudogene) -2.75211
NUP98 nucleoporin 98kDa -2.74333
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase -2.72174
FERMT3 fermitin family member 3 -2.70682
EXOC3L2 exocyst complex component 3-like 2 -2.70682
SETD3 SET domain containing 3 -2.65394
MYO15A myosin XVA -2.57486
ZNF25 zinc finger protein 25 -2.57486
CCNH cyclin H -2.57053
AARS1 alanyl-tRNA synthetase 1 -2.48573
UBE2B ubiquitin-conjugating enzyme E2B -2.46326
HIPK1 homeodomain interacting protein kinase 1 -2.42167
NUP54 nucleoporin 54kDa -2.40038
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 -2.36212
ZNF326 zinc finger protein 326 -2.34053
KIF1B kinesin family member 1B -2.33101
PDE12 phosphodiesterase 12 -2.33101
ANAPC4 anaphase promoting complex subunit 4 -2.32715
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -2.32335
ZNF490 zinc finger protein 490 -2.30898
CLK4 CDC-like kinase 4 -2.30176
KBTBD12 kelch repeat and BTB (POZ) domain containing 12 -2.288
CHID1 chitinase domain containing 1 -2.27415
CCDC22 coiled-coil domain containing 22 -2.26342
NBPF15 neuroblastoma breakpoint family, member 15 -2.2598
RHOXF1 Rhox homeobox family, member 1 -2.2598
SHLD2 shieldin complex subunit 2 -2.24224
CBX5 chromobox homolog 5 -2.22477
SCAF8 SR-related CTD-associated factor 8 -2.21926
PPP2R1B protein phosphatase 2, regulatory subunit A, beta -2.20738
VBP1 von Hippel-Lindau binding protein 1 -2.20528
SOX7 SRY (sex determining region Y)-box 7 -2.18876
SOX30 SRY (sex determining region Y)-box 30 -2.18876
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A -2.18218
GCLM glutamate-cysteine ligase, modifier subunit -2.16798
SLC44A2 solute carrier family 44 (choline transporter), member 2 -2.13824
PRMT1 protein arginine methyltransferase 1 -2.13824
RPS19BP1 ribosomal protein S19 binding protein 1 -2.12377
NOXRED1 NADP-dependent oxidoreductase domain containing 1 -2.12354
RPL37 ribosomal protein L37 -2.10307
DCAF13 DDB1 and CUL4 associated factor 13 -2.0932
TSPAN31 tetraspanin 31 -2.0932
ZNF862 zinc finger protein 862 -2.09224
MRPS18B mitochondrial ribosomal protein S18B -2.07927
TEX2 testis expressed 2 -2.07148
COX6B2 cytochrome c oxidase subunit VIb polypeptide 2 (testis) -2.05503
ADCY2 adenylate cyclase 2 (brain) -2.05433
ETF1 eukaryotic translation termination factor 1 -2.05433
TMEM125 transmembrane protein 125 -2.03354
FES FES proto-oncogene, tyrosine kinase -2.03354
MCM5 minichromosome maintenance complex component 5 -2.03071
TMEM250 transmembrane protein 250 -2.02682
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 -2.02507
STIM2 stromal interaction molecule 2 -2.01652
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -2.01652
ZBTB1 zinc finger and BTB domain containing 1 -2.01562
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.01562
FRMD8 FERM domain containing 8 -2.01165
BUB3 BUB3 mitotic checkpoint protein -2.00686