HOXB4 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description homeobox B4|This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3214)
External Link http://www.ncbi.nlm.nih.gov/gene/3214
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Genes

6 interacting proteins for HOXB4 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
CREBBP CREB binding protein
CUL4A cullin 4A
DDB1 damage-specific DNA binding protein 1, 127kDa
EP300 E1A binding protein p300
MEIS1 Meis homeobox 1
RBX1 ring-box 1, E3 ubiquitin protein ligase