HOXD13 Gene Set

Dataset ChEA Transcription Factor Targets
Category genomics
Type transcription factor
Description homeobox D13|This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. Mutations in this particular gene cause synpolydactyly. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3239)
External Link http://www.ncbi.nlm.nih.gov/gene/3239
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Genes

174 target genes of the HOXD13 transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.

Symbol Name
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ABHD2 abhydrolase domain containing 2
ABI2 abl-interactor 2
ACLY ATP citrate lyase
ACVR1C activin A receptor, type IC
ADA adenosine deaminase
AFF1 AF4/FMR2 family, member 1
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
ANAPC4 anaphase promoting complex subunit 4
ANGPT4 angiopoietin 4
ANK1 ankyrin 1, erythrocytic
ANKRD32 ankyrin repeat domain 32
ANO2 anoctamin 2, calcium activated chloride channel
ARID2 AT rich interactive domain 2 (ARID, RFX-like)
BARX1 BARX homeobox 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BTBD11 BTB (POZ) domain containing 11
BTG2 BTG family, member 2
CCAR1 cell division cycle and apoptosis regulator 1
CCNG1 cyclin G1
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDH12 cadherin 12, type 2 (N-cadherin 2)
CENPF centromere protein F, 350/400kDa
CENPI centromere protein I
CFP complement factor properdin
CHD9 chromodomain helicase DNA binding protein 9
CHN2 chimerin 2
COL11A1 collagen, type XI, alpha 1
COL18A1 collagen, type XVIII, alpha 1
COL4A1 collagen, type IV, alpha 1
COX5A cytochrome c oxidase subunit Va
CSMD3 CUB and Sushi multiple domains 3
CTNNBL1 catenin, beta like 1
DACH1 dachshund family transcription factor 1
DCP1B decapping mRNA 1B
DIAPH3 diaphanous-related formin 3
DICER1 dicer 1, ribonuclease type III
DLC1 DLC1 Rho GTPase activating protein
DMRT1 doublesex and mab-3 related transcription factor 1
DPP8 dipeptidyl-peptidase 8
DSCR10 Down syndrome critical region 10 (non-protein coding)
DTNA dystrobrevin, alpha
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
EI24 etoposide induced 2.4
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EMX1 empty spiracles homeobox 1
EMX2 empty spiracles homeobox 2
EPHA7 EPH receptor A7
ERAS ES cell expressed Ras
ESD esterase D
ESX1 ESX homeobox 1
EVC Ellis van Creveld protein
EVC2 Ellis van Creveld syndrome 2
FAM46C family with sequence similarity 46, member C
FBN1 fibrillin 1
FBXL3 F-box and leucine-rich repeat protein 3
FBXO9 F-box protein 9
FERMT3 fermitin family member 3
FOXC1 forkhead box C1
FOXL2 forkhead box L2
FOXN1 forkhead box N1
FRMD4A FERM domain containing 4A
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GKN1 gastrokine 1
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GPR160 G protein-coupled receptor 160
GPR180 G protein-coupled receptor 180
GPS2 G protein pathway suppressor 2
HAND2 heart and neural crest derivatives expressed 2
HDDC3 HD domain containing 3
HES7 hes family bHLH transcription factor 7
HIST1H4F histone cluster 1, H4f
HIST2H4A histone cluster 2, H4a
HOXA7 homeobox A7
HPSE2 heparanase 2 (inactive)
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
ICE2 interactor of little elongation complex ELL subunit 2
ICK intestinal cell (MAK-like) kinase
IGF1R insulin-like growth factor 1 receptor
IL20RA interleukin 20 receptor, alpha
IL4R interleukin 4 receptor
INTS6 integrator complex subunit 6
ITGB8 integrin, beta 8
JARID2 jumonji, AT rich interactive domain 2
KLK2 kallikrein-related peptidase 2
LEMD3 LEM domain containing 3
LGMN legumain
LHX9 LIM homeobox 9
LOX lysyl oxidase
LUZP4 leucine zipper protein 4
MAML1 mastermind-like 1 (Drosophila)
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2
MDN1 MDN1, midasin homolog (yeast)
MEA1 male-enhanced antigen 1
MGST3 microsomal glutathione S-transferase 3
MPZL1 myelin protein zero-like 1
MXRA5 matrix-remodelling associated 5
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2
NAP1L1 nucleosome assembly protein 1-like 1
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NELL2 NEL-like 2 (chicken)
NLGN1 neuroligin 1
NODAL nodal growth differentiation factor
NOL4 nucleolar protein 4
NPTN neuroplastin
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRSN1 neurensin 1
NTN4 netrin 4
OPA1 optic atrophy 1 (autosomal dominant)
ORC4 origin recognition complex, subunit 4
PAX6 paired box 6
PCDHGB1 protocadherin gamma subfamily B, 1
PCM1 pericentriolar material 1
PCNA proliferating cell nuclear antigen
PGAM1 phosphoglycerate mutase 1 (brain)
PIAS2 protein inhibitor of activated STAT, 2
PITX3 paired-like homeodomain 3
POT1 protection of telomeres 1
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
RAB33A RAB33A, member RAS oncogene family
RAB37 RAB37, member RAS oncogene family
RAB3C RAB3C, member RAS oncogene family
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGS2 regulator of G-protein signaling 2
RHBDL2 rhomboid, veinlet-like 2 (Drosophila)
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RP9 retinitis pigmentosa 9 (autosomal dominant)
RPL30 ribosomal protein L30
SCGN secretagogin, EF-hand calcium binding protein
SENP1 SUMO1/sentrin specific peptidase 1
SIX3 SIX homeobox 3
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SMYD5 SMYD family member 5
SORBS2 sorbin and SH3 domain containing 2
SORCS2 sortilin-related VPS10 domain containing receptor 2
SOX14 SRY (sex determining region Y)-box 14
SPHK1 sphingosine kinase 1
SSPN sarcospan
STAB2 stabilin 2
STK38L serine/threonine kinase 38 like
SUFU suppressor of fused homolog (Drosophila)
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
TBC1D5 TBC1 domain family, member 5
TBP TATA box binding protein
TBX15 T-box 15
TES testin LIM domain protein
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
THOC1 THO complex 1
TIAM1 T-cell lymphoma invasion and metastasis 1
TLL1 tolloid-like 1
TRAPPC10 trafficking protein particle complex 10
TRIM7 tripartite motif containing 7
TRIM8 tripartite motif containing 8
TTK TTK protein kinase
UBE2F ubiquitin-conjugating enzyme E2F (putative)
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UNG uracil-DNA glycosylase
UPP1 uridine phosphorylase 1
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP48 ubiquitin specific peptidase 48
WDR1 WD repeat domain 1
WDR4 WD repeat domain 4
WDTC1 WD and tetratricopeptide repeats 1
XAB2 XPA binding protein 2
YIPF3 Yip1 domain family, member 3
ZNF12 zinc finger protein 12
ZNF160 zinc finger protein 160
ZNF516 zinc finger protein 516