HP-163 Gene Set
Genes
14 genes differentially expressed following the HP-163 small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
TXNRD1
|
thioredoxin reductase 1
|
3.87965
|
|
NQO2
|
NAD(P)H dehydrogenase, quinone 2
|
3.49927
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.38151
|
|
SMC1A
|
structural maintenance of chromosomes 1A
|
3.32
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
3.19634
|
|
GPX2
|
glutathione peroxidase 2
|
3.16012
|
|
FMO1
|
flavin containing monooxygenase 1
|
3.10927
|
|
CD36
|
CD36 molecule (thrombospondin receptor)
|
3.10182
|
|
ECM2
|
extracellular matrix protein 2, female organ and adipocyte specific
|
3.08686
|
|
RASA4
|
RAS p21 protein activator 4
|
3.02747
|
|
EAPP
|
E2F-associated phosphoprotein
|
3.00664
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PSMD10
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
|
-3.44227
|
|
BMI1
|
BMI1 proto-oncogene, polycomb ring finger
|
-3.01326
|
|
SPAG4
|
sperm associated antigen 4
|
-3.00607
|
