HPN Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description hepsin|This gene encodes a type II transmembrane serine protease that may be involved in diverse cellular functions, including blood coagulation and the maintenance of cell morphology. Expression of the encoded protein is associated with the growth and progression of cancers, particularly prostate cancer. The protein is cleaved into a catalytic serine protease chain and a non-catalytic scavenger receptor cysteine-rich chain, which associate via a single disulfide bond. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] (NCBI Entrez Gene Database, 3249)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_HPN
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Genes

133 co-expressed genes for HPN from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACOX2 acyl-CoA oxidase 2, branched chain
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADH6 alcohol dehydrogenase 6 (class V)
AGXT alanine-glyoxylate aminotransferase
AHSG alpha-2-HS-glycoprotein
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALDOB aldolase B, fructose-bisphosphate
AMBP alpha-1-microglobulin/bikunin precursor
ANG angiogenin, ribonuclease, RNase A family, 5
APCS amyloid P component, serum
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOC1 apolipoprotein C-I
APOC2 apolipoprotein C-II
APOC3 apolipoprotein C-III
APOC4 apolipoprotein C-IV
APOF apolipoprotein F
APOH apolipoprotein H (beta-2-glycoprotein I)
ASGR2 asialoglycoprotein receptor 2
ASL argininosuccinate lyase
ASS1 argininosuccinate synthase 1
ATF5 activating transcription factor 5
C19ORF80 chromosome 19 open reading frame 80
C3 complement component 3
C4BPA complement component 4 binding protein, alpha
C4BPB complement component 4 binding protein, beta
C6 complement component 6
C8A complement component 8, alpha polypeptide
C8B complement component 8, beta polypeptide
C8G complement component 8, gamma polypeptide
CDHR5 cadherin-related family member 5
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CES1 carboxylesterase 1
CES2 carboxylesterase 2
CFB complement factor B
CIDEB cell death-inducing DFFA-like effector b
CPN2 carboxypeptidase N, polypeptide 2
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DCXR dicarbonyl/L-xylulose reductase
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial
F10 coagulation factor X
F12 coagulation factor XII (Hageman factor)
F2 coagulation factor II (thrombin)
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FETUB fetuin B
FTCD formimidoyltransferase cyclodeaminase
GAMT guanidinoacetate N-methyltransferase
GJB1 gap junction protein, beta 1, 32kDa
GNMT glycine N-methyltransferase
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTZ1 glutathione S-transferase zeta 1
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HABP2 hyaluronan binding protein 2
HAMP hepcidin antimicrobial peptide
HGFAC HGF activator
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HP haptoglobin
HPD 4-hydroxyphenylpyruvate dioxygenase
HPN hepsin
HPR haptoglobin-related protein
HPX hemopexin
HRG histidine-rich glycoprotein
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IGFALS insulin-like growth factor binding protein, acid labile subunit
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KHK ketohexokinase (fructokinase)
LCAT lecithin-cholesterol acyltransferase
MASP2 mannan-binding lectin serine peptidase 2
MAT1A methionine adenosyltransferase I, alpha
NNMT nicotinamide N-methyltransferase
ORM1 orosomucoid 1
ORM2 orosomucoid 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PEMT phosphatidylethanolamine N-methyltransferase
PIPOX pipecolic acid oxidase
PLG plasminogen
PON1 paraoxonase 1
PON3 paraoxonase 3
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PRODH2 proline dehydrogenase (oxidase) 2
PXMP2 peroxisomal membrane protein 2, 22kDa
QPRT quinolinate phosphoribosyltransferase
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBP4 retinol binding protein 4, plasma
RDH16 retinol dehydrogenase 16 (all-trans)
SAA4 serum amyloid A4, constitutive
SARDH sarcosine dehydrogenase
SDS serine dehydratase
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC38A3 solute carrier family 38, member 3
SPP2 secreted phosphoprotein 2, 24kDa
TAT tyrosine aminotransferase
TKFC triokinase/FMN cyclase
TM4SF5 transmembrane 4 L six family member 5
TMEM176A transmembrane protein 176A
TMEM176B transmembrane protein 176B
TMPRSS6 transmembrane protease, serine 6
TST thiosulfate sulfurtransferase (rhodanese)
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
UPB1 ureidopropionase, beta
VTN vitronectin
ZG16 zymogen granule protein 16
ZGPAT zinc finger, CCCH-type with G patch domain