HRI Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description eukaryotic translation initiation factor 2-alpha kinase 1|The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] (NCBI Entrez Gene Database, 27102)
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Genes

100 substrates of the kinase HRI from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
PPP1R8 protein phosphatase 1, regulatory subunit 8
RACGAP1 Rac GTPase activating protein 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
NFE2L2 nuclear factor, erythroid 2-like 2
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
AIP aryl hydrocarbon receptor interacting protein
SRSF7 serine/arginine-rich splicing factor 7
SRC SRC proto-oncogene, non-receptor tyrosine kinase
AKAP17A A kinase (PRKA) anchor protein 17A
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
RPS14 ribosomal protein S14
TOR4A torsin family 4, member A
MC4R melanocortin 4 receptor
PRICKLE1 prickle homolog 1 (Drosophila)
ANKRD12 ankyrin repeat domain 12
TRAT1 T cell receptor associated transmembrane adaptor 1
RET ret proto-oncogene
VRK2 vaccinia related kinase 2
FFAR4 free fatty acid receptor 4
AP1M2 adaptor-related protein complex 1, mu 2 subunit
AP1M1 adaptor-related protein complex 1, mu 1 subunit
PKP4 plakophilin 4
PKP2 plakophilin 2
PVRL4 poliovirus receptor-related 4
PTGDR2 prostaglandin D2 receptor 2
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
RTTN rotatin
UBE4B ubiquitination factor E4B
ADGRG6 adhesion G protein-coupled receptor G6
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
MYH1 myosin, heavy chain 1, skeletal muscle, adult
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYH4 myosin, heavy chain 4, skeletal muscle
GORAB golgin, RAB6-interacting
CWF19L2 CWF19-like 2, cell cycle control (S. pombe)
RPL26 ribosomal protein L26
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
GRB2 growth factor receptor-bound protein 2
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
ZNF22 zinc finger protein 22
MOB3A MOB kinase activator 3A
THOC5 THO complex 5
SFPQ splicing factor proline/glutamine-rich
FAM133B family with sequence similarity 133, member B
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
ABR active BCR-related
YIPF5 Yip1 domain family, member 5
ILF3 interleukin enhancer binding factor 3, 90kDa
DKC1 dyskeratosis congenita 1, dyskerin
SV2A synaptic vesicle glycoprotein 2A
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
PNP purine nucleoside phosphorylase
ARHGAP21 Rho GTPase activating protein 21
NUP85 nucleoporin 85kDa
SOGA1 suppressor of glucose, autophagy associated 1
TBCB tubulin folding cofactor B
CEP170 centrosomal protein 170kDa
GPATCH11 G patch domain containing 11
PRKD3 protein kinase D3
PRKD2 protein kinase D2
PRKD1 protein kinase D1
ADSL adenylosuccinate lyase
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
KLC2 kinesin light chain 2
TICRR TOPBP1-interacting checkpoint and replication regulator
ITGB5 integrin, beta 5
SLC45A4 solute carrier family 45, member 4
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
ATRX alpha thalassemia/mental retardation syndrome X-linked
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
FOXO3 forkhead box O3
EIF3A eukaryotic translation initiation factor 3, subunit A
CDK12 cyclin-dependent kinase 12
PTK2 protein tyrosine kinase 2
NKTR natural killer cell triggering receptor
LATS2 large tumor suppressor kinase 2
LATS1 large tumor suppressor kinase 1
HEPH hephaestin
TNS3 tensin 3
TJP2 tight junction protein 2
TJP1 tight junction protein 1
RPL26L1 ribosomal protein L26-like 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
MPZ myelin protein zero
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ANXA6 annexin A6
PPP1R12A protein phosphatase 1, regulatory subunit 12A
ZNF407 zinc finger protein 407
SMTN smoothelin
DEF6 differentially expressed in FDCP 6 homolog (mouse)
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
WAC WW domain containing adaptor with coiled-coil
FTSJ3 FtsJ homolog 3 (E. coli)
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
EPS8 epidermal growth factor receptor pathway substrate 8