HS+LS_3min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] Gene Set

Dataset SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs
Category proteomics
Type drug perturbation
Description drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]] (SILAC Phosphoproteomics)
Similar Terms
Downloads & Tools

Genes

85 proteins differentially phosphorylated following the HS+LS_3min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] drug perturbation from the SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs dataset.

increased phosphorylation

Symbol Name
AAK1 AP2 associated kinase 1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
BCKDK branched chain ketoacid dehydrogenase kinase
BMP2K BMP2 inducible kinase
C2CD5 C2 calcium-dependent domain containing 5
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CANX calnexin
CCNE1 cyclin E1
CCNK cyclin K
CDK12 cyclin-dependent kinase 12
CDK13 cyclin-dependent kinase 13
CDK16 cyclin-dependent kinase 16
CDK17 cyclin-dependent kinase 17
CDK18 cyclin-dependent kinase 18
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CFL1 cofilin 1 (non-muscle)
CHEK1 checkpoint kinase 1
CLTC clathrin, heavy chain (Hc)
CSNK2B casein kinase 2, beta polypeptide
DOCK2 dedicator of cytokinesis 2
DPF2 D4, zinc and double PHD fingers family 2
EDC4 enhancer of mRNA decapping 4
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
EIF3C eukaryotic translation initiation factor 3, subunit C
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HACD3 3-hydroxyacyl-CoA dehydratase 3
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPH1 heat shock 105kDa/110kDa protein 1
JUN jun proto-oncogene
LARP1 La ribonucleoprotein domain family, member 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MNAT1 MNAT CDK-activating kinase assembly factor 1
MYBBP1A MYB binding protein (P160) 1a
MYO9B myosin IXB
PELP1 proline, glutamate and leucine rich protein 1
PKN2 protein kinase N2
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PUM2 pumilio RNA-binding family member 2
RAVER1 ribonucleoprotein, PTB-binding 1
RBM39 RNA binding motif protein 39
RIPK2 receptor-interacting serine-threonine kinase 2
RPL18 ribosomal protein L18
RPS3 ribosomal protein S3
RPS6 ribosomal protein S6
RRM2 ribonucleotide reductase M2
SLK STE20-like kinase
SMN1 survival of motor neuron 1, telomeric
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
STK10 serine/threonine kinase 10
STK19 serine/threonine kinase 19
STK3 serine/threonine kinase 3
STK4 serine/threonine kinase 4
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TANK TRAF family member-associated NFKB activator
TCP1 t-complex 1
TK1 thymidine kinase 1, soluble
TRIM28 tripartite motif containing 28
UBL7 ubiquitin-like 7
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UVRAG UV radiation resistance associated
VAMP4 vesicle-associated membrane protein 4
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZC3H18 zinc finger CCCH-type containing 18

decreased phosphorylation

Symbol Name
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
CCNC cyclin C
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
MAPK8 mitogen-activated protein kinase 8
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3