HS-445 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: lymphoma; Hodgkins disease (Cell Line Ontology, CLO_0003962)
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Genes

262 genes mutated in the HS-445 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
AAK1 AP2 associated kinase 1
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
ACOX3 acyl-CoA oxidase 3, pristanoyl
ACSS2 acyl-CoA synthetase short-chain family member 2
ACTN4 actinin, alpha 4
ADCY2 adenylate cyclase 2 (brain)
ADGRF5 adhesion G protein-coupled receptor F5
ADGRV1 adhesion G protein-coupled receptor V1
ADSS adenylosuccinate synthase
AGRN agrin
ALOX15 arachidonate 15-lipoxygenase
ANKHD1 ankyrin repeat and KH domain containing 1
ANKHD1-EIF4EBP3 ANKHD1-EIF4EBP3 readthrough
ANKRD24 ankyrin repeat domain 24
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AQP12B aquaporin 12B
ARFGEF3 ARFGEF family member 3
ARHGAP20 Rho GTPase activating protein 20
ARHGAP26 Rho GTPase activating protein 26
ARHGAP32 Rho GTPase activating protein 32
ARHGAP9 Rho GTPase activating protein 9
ARSB arylsulfatase B
ATP10A ATPase, class V, type 10A
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BIRC2 baculoviral IAP repeat containing 2
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BSN bassoon presynaptic cytomatrix protein
BTG1 B-cell translocation gene 1, anti-proliferative
CAND1 cullin-associated and neddylation-dissociated 1
CCDC160 coiled-coil domain containing 160
CCDC61 coiled-coil domain containing 61
CCDC73 coiled-coil domain containing 73
CCNB3 cyclin B3
CDH18 cadherin 18, type 2
CELA2A chymotrypsin-like elastase family, member 2A
CEP95 centrosomal protein 95kDa
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CIR1 corepressor interacting with RBPJ, 1
CLCN4 chloride channel, voltage-sensitive 4
CLK2 CDC-like kinase 2
CNBD1 cyclic nucleotide binding domain containing 1
CNTN5 contactin 5
CNTNAP3B contactin associated protein-like 3B
COG7 component of oligomeric golgi complex 7
COX6B1P3 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) pseudogene 3
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8
CPM carboxypeptidase M
CPNE2 copine II
CSMD1 CUB and Sushi multiple domains 1
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTXN1 cortexin 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
DAZAP1 DAZ associated protein 1
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53
DNAH3 dynein, axonemal, heavy chain 3
DNAH8 dynein, axonemal, heavy chain 8
DOK5 docking protein 5
DSG2 desmoglein 2
DSPP dentin sialophosphoprotein
DTX4 deltex 4, E3 ubiquitin ligase
DZIP1 DAZ interacting zinc finger protein 1
EBF3 early B-cell factor 3
EGFR epidermal growth factor receptor
EID3 EP300 interacting inhibitor of differentiation 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EME2 essential meiotic structure-specific endonuclease subunit 2
EP400 E1A binding protein p400
EPHA2 EPH receptor A2
EPHA5 EPH receptor A5
ERBB3 erb-b2 receptor tyrosine kinase 3
FAM151A family with sequence similarity 151, member A
FAM3A family with sequence similarity 3, member A
FAT3 FAT atypical cadherin 3
FBLIM1 filamin binding LIM protein 1
FLG2 filaggrin family member 2
FLII flightless I homolog (Drosophila)
FLNB filamin B, beta
FRRS1 ferric-chelate reductase 1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FZD4 frizzled class receptor 4
G6PC2 glucose-6-phosphatase, catalytic, 2
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GBP7 guanylate binding protein 7
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNPDA1 glucosamine-6-phosphate deaminase 1
GOLGA3 golgin A3
GPR161 G protein-coupled receptor 161
GPSM2 G-protein signaling modulator 2
GRIA3 glutamate receptor, ionotropic, AMPA 3
HDAC7 histone deacetylase 7
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HLA-B major histocompatibility complex, class I, B
HNRNPM heterogeneous nuclear ribonucleoprotein M
HYAL3 hyaluronoglucosaminidase 3
IGDCC3 immunoglobulin superfamily, DCC subclass, member 3
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1
INO80E INO80 complex subunit E
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IPO4 importin 4
ITPKB inositol-trisphosphate 3-kinase B
JAKMIP1 janus kinase and microtubule interacting protein 1
KANSL1 KAT8 regulatory NSL complex subunit 1
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
KIAA1033 KIAA1033
KIAA1671 KIAA1671
KIRREL kin of IRRE like (Drosophila)
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1
KRT35 keratin 35, type I
KRT86 keratin 86, type II
LAMA5 laminin, alpha 5
LCMT2 leucine carboxyl methyltransferase 2
LENG8 leukocyte receptor cluster (LRC) member 8
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LMTK1 lemur tail kinase 1
LOXL2 lysyl oxidase-like 2
LRP1B low density lipoprotein receptor-related protein 1B
LRP2 low density lipoprotein receptor-related protein 2
MAP2K2 mitogen-activated protein kinase kinase 2
MAST2 microtubule associated serine/threonine kinase 2
MATK megakaryocyte-associated tyrosine kinase
MCF2L MCF.2 cell line derived transforming sequence-like
MCM3AP minichromosome maintenance complex component 3 associated protein
MCM4 minichromosome maintenance complex component 4
MED12L mediator complex subunit 12-like
MEGF11 multiple EGF-like-domains 11
METTL3 methyltransferase like 3
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MICU2 mitochondrial calcium uptake 2
MRPL9 mitochondrial ribosomal protein L9
MRPS9 mitochondrial ribosomal protein S9
MTF1 metal-regulatory transcription factor 1
MTMR7 myotubularin related protein 7
MUC12 mucin 12, cell surface associated
MUC4 mucin 4, cell surface associated
MX1 MX dynamin-like GTPase 1
MYO16 myosin XVI
MYO5B myosin VB
NCAPD2 non-SMC condensin I complex, subunit D2
NCOA1 nuclear receptor coactivator 1
NCOA3 nuclear receptor coactivator 3
NEMF nuclear export mediator factor
NFASC neurofascin
NLRP4 NLR family, pyrin domain containing 4
NR2C1 nuclear receptor subfamily 2, group C, member 1
NRP2 neuropilin 2
NRSN2 neurensin 2
NTM neurotrimin
NUP88 nucleoporin 88kDa
OCRL oculocerebrorenal syndrome of Lowe
OLFM4 olfactomedin 4
OR13J1 olfactory receptor, family 13, subfamily J, member 1
OR51E2 olfactory receptor, family 51, subfamily E, member 2
OTOL1 otolin 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDZD7 PDZ domain containing 7
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PHYH phytanoyl-CoA 2-hydroxylase
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
PITRM1 pitrilysin metallopeptidase 1
PLA2R1 phospholipase A2 receptor 1, 180kDa
PLXNA1 plexin A1
PLXNA3 plexin A3
POGZ pogo transposable element with ZNF domain
POM121 POM121 transmembrane nucleoporin
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PRB2 proline-rich protein BstNI subfamily 2
PROCA1 protein interacting with cyclin A1
PRPF38A pre-mRNA processing factor 38A
PTPRG protein tyrosine phosphatase, receptor type, G
PTPRN protein tyrosine phosphatase, receptor type, N
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PXDN peroxidasin
QRICH2 glutamine rich 2
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RBFA ribosome binding factor A (putative)
REV1 REV1, polymerase (DNA directed)
RGS20 regulator of G-protein signaling 20
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPE65 retinal pigment epithelium-specific protein 65kDa
RTN4 reticulon 4
SAFB2 scaffold attachment factor B2
SCN9A sodium channel, voltage gated, type IX alpha subunit
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SETBP1 SET binding protein 1
SH3BP5L SH3-binding domain protein 5-like
SHROOM2 shroom family member 2
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SMG5 SMG5 nonsense mediated mRNA decay factor
SNX5 sorting nexin 5
SON SON DNA binding protein
SPHK2 sphingosine kinase 2
SPTBN1 spectrin, beta, non-erythrocytic 1
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1
SRP68 signal recognition particle 68kDa
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
STK36 serine/threonine kinase 36
SYCP2 synaptonemal complex protein 2
SYNE1 spectrin repeat containing, nuclear envelope 1
SYT6 synaptotagmin VI
SYT7 synaptotagmin VII
TBC1D10B TBC1 domain family, member 10B
TBC1D2 TBC1 domain family, member 2
TBC1D2B TBC1 domain family, member 2B
TBC1D31 TBC1 domain family, member 31
TCP10L t-complex 10-like
TDH L-threonine dehydrogenase (pseudogene)
TDRD1 tudor domain containing 1
TMEM98 transmembrane protein 98
TOP3B topoisomerase (DNA) III beta
TPRA1 transmembrane protein, adipocyte asscociated 1
TRIM4 tripartite motif containing 4
TRPM5 transient receptor potential cation channel, subfamily M, member 5
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TRRAP transformation/transcription domain-associated protein
TSPAN8 tetraspanin 8
TTBK2 tau tubulin kinase 2
TUBB8 tubulin, beta 8 class VIII
UBXN10 UBX domain protein 10
UNC13A unc-13 homolog A (C. elegans)
USH2A Usher syndrome 2A (autosomal recessive, mild)
USP24 ubiquitin specific peptidase 24
VWF von Willebrand factor
WDR45B WD repeat domain 45B
WDR59 WD repeat domain 59
WWOX WW domain containing oxidoreductase
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YEATS2 YEATS domain containing 2
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZBTB17 zinc finger and BTB domain containing 17
ZDBF2 zinc finger, DBF-type containing 2
ZDHHC21 zinc finger, DHHC-type containing 21
ZFHX4 zinc finger homeobox 4
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF22 zinc finger protein 22
ZNF235 zinc finger protein 235
ZNF268 zinc finger protein 268
ZNF426 zinc finger protein 426
ZNF518B zinc finger protein 518B
ZNF641 zinc finger protein 641
ZNF812 zinc finger protein 812
ZNF846 zinc finger protein 846
ZNF98 zinc finger protein 98
ZRANB3 zinc finger, RAN-binding domain containing 3
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
ZSCAN10 zinc finger and SCAN domain containing 10
ZSCAN22 zinc finger and SCAN domain containing 22
ZSCAN5D zinc finger and SCAN domain containing 5D