HSPA8 Gene Set

Dataset Hub Proteins Protein-Protein Interactions
Category physical interactions
Type hub protein
Description heat shock 70kDa protein 8|This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 3312)
External Link http://www.ncbi.nlm.nih.gov/gene/3312
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178 interacting proteins for hub protein HSPA8 from the curated Hub Proteins Protein-Protein Interactions dataset.

Symbol Name
ABI1 abl-interactor 1
ACTB actin, beta
ALDOB aldolase B, fructose-bisphosphate
APOB apolipoprotein B
APP amyloid beta (A4) precursor protein
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
BAG1 BCL2-associated athanogene
BAG2 BCL2-associated athanogene 2
BAG3 BCL2-associated athanogene 3
BAG4 BCL2-associated athanogene 4
BAG6 BCL2-associated athanogene 6
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRMS1 breast cancer metastasis suppressor 1
CCND1 cyclin D1
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CD40 CD40 molecule, TNF receptor superfamily member 5
CDC5L cell division cycle 5-like
CDK11B cyclin-dependent kinase 11B
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CENPA centromere protein A
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHRM1 cholinergic receptor, muscarinic 1
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLTA clathrin, light chain A
CLTC clathrin, heavy chain (Hc)
COL7A1 collagen, type VII, alpha 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCR4 chemokine (C-X-C motif) receptor 4
CYCS cytochrome c, somatic
DLG4 discs, large homolog 4 (Drosophila)
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DPP3 dipeptidyl-peptidase 3
DYNLL1 dynein, light chain, LC8-type 1
EGFR epidermal growth factor receptor
EPRS glutamyl-prolyl-tRNA synthetase
ERH enhancer of rudimentary homolog (Drosophila)
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FANCC Fanconi anemia, complementation group C
FBP1 fructose-1,6-bisphosphatase 1
FTL ferritin, light polypeptide
GABARAP GABA(A) receptor-associated protein
GABARAPL1 GABA(A) receptor-associated protein like 1
GABARAPL2 GABA(A) receptor-associated protein-like 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAK cyclin G associated kinase
GCH1 GTP cyclohydrolase 1
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPN1 GPN-loop GTPase 1
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GRB2 growth factor receptor-bound protein 2
HCFC1 host cell factor C1
HDAC10 histone deacetylase 10
HDAC3 histone deacetylase 3
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIP1 huntingtin interacting protein 1
HIST3H3 histone cluster 3, H3
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPK heterogeneous nuclear ribonucleoprotein K
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
HSPH1 heat shock 105kDa/110kDa protein 1
HTT huntingtin
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL16 interleukin 16
IL7R interleukin 7 receptor
IRAK1 interleukin-1 receptor-associated kinase 1
IRS1 insulin receptor substrate 1
ITGB4 integrin, beta 4
JAK2 Janus kinase 2
JUN jun proto-oncogene
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP2K1 mitogen-activated protein kinase kinase 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK10 mitogen-activated protein kinase 10
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPT microtubule-associated protein tau
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEN1 multiple endocrine neoplasia I
MME membrane metallo-endopeptidase
MST1R macrophage stimulating 1 receptor
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NLRP12 NLR family, pyrin domain containing 12
NOA1 nitric oxide associated 1
PACSIN1 protein kinase C and casein kinase substrate in neurons 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PARK2 parkin RBR E3 ubiquitin protein ligase
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PGR progesterone receptor
PHC1 polyhomeotic homolog 1 (Drosophila)
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPID peptidylprolyl isomerase D
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RAD52 RAD52 homolog (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1 retinoblastoma 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
RCC1 regulator of chromosome condensation 1
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RGS2 regulator of G-protein signaling 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK2 receptor-interacting serine-threonine kinase 2
RIPK3 receptor-interacting serine-threonine kinase 3
RNF2 ring finger protein 2
RPAP1 RNA polymerase II associated protein 1
RUVBL1 RuvB-like AAA ATPase 1
SEC61B Sec61 beta subunit
SERP1 stress-associated endoplasmic reticulum protein 1
SF3A2 splicing factor 3a, subunit 2, 66kDa
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SOD1 superoxide dismutase 1, soluble
SP1 Sp1 transcription factor
SQSTM1 sequestosome 1
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
STMN1 stathmin 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUMO2 small ubiquitin-like modifier 2
SUMO4 small ubiquitin-like modifier 4
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TADA3 transcriptional adaptor 3
TANK TRAF family member-associated NFKB activator
TBK1 TANK-binding kinase 1
TCERG1 transcription elongation regulator 1
TCP1 t-complex 1
TM4SF1 transmembrane 4 L six family member 1
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TP53 tumor protein p53
TRADD TNFRSF1A-associated via death domain
TRAF1 TNF receptor-associated factor 1
TRAF2 TNF receptor-associated factor 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TSC2 tuberous sclerosis 2
TSSK6 testis-specific serine kinase 6
TUBA1A tubulin, alpha 1a
UBB ubiquitin B
UBC ubiquitin C
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VCL vinculin
VCP valosin containing protein
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta