HS_30min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] Gene Set

Dataset SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs
Category proteomics
Type drug perturbation
Description drug perturbation identified as [drug perturbation]_[cell line] ([organism]) [[publication PMID]] (SILAC Phosphoproteomics)
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Genes

110 proteins differentially phosphorylated following the HS_30min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745] drug perturbation from the SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs dataset.

increased phosphorylation

Symbol Name
AAK1 AP2 associated kinase 1
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACLY ATP citrate lyase
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGAP10 Rho GTPase activating protein 10
ATXN2L ataxin 2-like
AZI2 5-azacytidine induced 2
BMP2K BMP2 inducible kinase
BTK Bruton agammaglobulinemia tyrosine kinase
C2CD5 C2 calcium-dependent domain containing 5
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCDC132 coiled-coil domain containing 132
CCNT1 cyclin T1
CCNT2 cyclin T2
CDK13 cyclin-dependent kinase 13
CDK16 cyclin-dependent kinase 16
CDK17 cyclin-dependent kinase 17
CDK18 cyclin-dependent kinase 18
CDK5 cyclin-dependent kinase 5
CETN2 centrin, EF-hand protein, 2
CLDN11 claudin 11
COG3 component of oligomeric golgi complex 3
DENND1A DENN/MADD domain containing 1A
EDC4 enhancer of mRNA decapping 4
ELL2 elongation factor, RNA polymerase II, 2
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
FAM83G family with sequence similarity 83, member G
FER fer (fps/fes related) tyrosine kinase
FES FES proto-oncogene, tyrosine kinase
FGR FGR proto-oncogene, Src family tyrosine kinase
GAK cyclin G associated kinase
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GEMIN4 gem (nuclear organelle) associated protein 4
GEMIN7 gem (nuclear organelle) associated protein 7
GSK3A glycogen synthase kinase 3 alpha
GYS1 glycogen synthase 1 (muscle)
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
LARP1 La ribonucleoprotein domain family, member 1
LPXN leupaxin
LRRK2 leucine-rich repeat kinase 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK3 MAP/microtubule affinity-regulating kinase 3
MAVS mitochondrial antiviral signaling protein
MELK maternal embryonic leucine zipper kinase
MID1IP1 MID1 interacting protein 1
MIEF1 mitochondrial elongation factor 1
MON2 MON2 homolog (S. cerevisiae)
MOV10 Mov10 RISC complex RNA helicase
NEK1 NIMA-related kinase 1
NEK9 NIMA-related kinase 9
NUP93 nucleoporin 93kDa
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
PHKB phosphorylase kinase, beta
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PKN1 protein kinase N1
PML promyelocytic leukemia
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKCE protein kinase C, epsilon
PRKCH protein kinase C, eta
PRKD2 protein kinase D2
PRKD3 protein kinase D3
PTK2B protein tyrosine kinase 2 beta
RAB6A RAB6A, member RAS oncogene family
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RIPK2 receptor-interacting serine-threonine kinase 2
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPTOR regulatory associated protein of MTOR, complex 1
SIK2 salt-inducible kinase 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SNAPIN SNAP-associated protein
SRP72 signal recognition particle 72kDa
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
TANK TRAF family member-associated NFKB activator
TBK1 TANK-binding kinase 1
TEC tec protein tyrosine kinase
TMEM115 transmembrane protein 115
TNIP2 TNFAIP3 interacting protein 2
TNS3 tensin 3
TRAM1 translocation associated membrane protein 1
TRRAP transformation/transcription domain-associated protein
TTK TTK protein kinase
TXLNA taxilin alpha
XPO4 exportin 4
ZAK sterile alpha motif and leucine zipper containing kinase AZK

decreased phosphorylation

Symbol Name
AP2M1 adaptor-related protein complex 2, mu 1 subunit
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CSF1R colony stimulating factor 1 receptor
ICK intestinal cell (MAK-like) kinase
KIAA0195 KIAA0195
MED13L mediator complex subunit 13-like
NEK2 NIMA-related kinase 2
NUAK2 NUAK family, SNF1-like kinase, 2
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5
PARVB parvin, beta
PRKACB protein kinase, cAMP-dependent, catalytic, beta
ULK3 unc-51 like kinase 3
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)