| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled|This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012] (NCBI Entrez Gene Database, 3350) |
| External Link | https://ncbi.nlm.nih.gov/gene/3350 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the HTR1A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.0167691 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0153574 |
| ADORA2B | adenosine A2b receptor | 0.0148729 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.01366 |
| S100A2 | S100 calcium binding protein A2 | 0.0136273 |
| POSTN | periostin, osteoblast specific factor | 0.0127764 |
| RXRA | retinoid X receptor, alpha | 0.0123144 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0121629 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.0121436 |
| TMEM14A | transmembrane protein 14A | 0.0121245 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0117802 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.011611 |
| PCNA | proliferating cell nuclear antigen | 0.0115102 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | 0.0115086 |
| GSTA4 | glutathione S-transferase alpha 4 | 0.0114424 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.0111725 |
| KIF20A | kinesin family member 20A | 0.010944 |
| BCHE | butyrylcholinesterase | 0.01094 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0107802 |
| PCLAF | PCNA clamp associated factor | 0.0105447 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 0.0104688 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.0104147 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.0102858 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.0101553 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.0100469 |
| COPS7A | COP9 signalosome subunit 7A | 0.010043 |
| CD84 | CD84 molecule | 0.00998644 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00994237 |
| TIPRL | TOR signaling pathway regulator | 0.00991905 |
| SDC2 | syndecan 2 | 0.00991062 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00985426 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00981644 |
| COLEC12 | collectin sub-family member 12 | 0.00981496 |
| HOPX | HOP homeobox | 0.00974138 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00971062 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00962682 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.009613 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00955895 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0094993 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00946545 |
| COL5A1 | collagen, type V, alpha 1 | 0.00945449 |
| PRC1 | protein regulator of cytokinesis 1 | 0.00944616 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 0.00940421 |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.00936968 |
| DUT | deoxyuridine triphosphatase | 0.00929343 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.00928366 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00926407 |
| FASN | fatty acid synthase | 0.00924024 |
| COL3A1 | collagen, type III, alpha 1 | 0.00922954 |
| RAPSN | receptor-associated protein of the synapse | 0.00922163 |
| KRT6A | keratin 6A, type II | 0.00918167 |
| CCNA2 | cyclin A2 | 0.00914056 |
| RHOA | ras homolog family member A | 0.00910749 |
| MEX3D | mex-3 RNA binding family member D | 0.00908196 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.00900158 |
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | 0.00890175 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.00890106 |
| IL2RB | interleukin 2 receptor, beta | 0.00886203 |
| HPGDS | hematopoietic prostaglandin D synthase | 0.00886104 |
| SLC2A4RG | SLC2A4 regulator | 0.00882271 |
| FAM3C | family with sequence similarity 3, member C | 0.00882099 |
| GAS1 | growth arrest-specific 1 | 0.00882029 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.00867241 |
| LMNB2 | lamin B2 | 0.00866772 |
| PRF1 | perforin 1 (pore forming protein) | 0.00864841 |
| DAPK1 | death-associated protein kinase 1 | 0.00862736 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00857334 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00854755 |
| PKM | pyruvate kinase, muscle | 0.00854589 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00849049 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00848279 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.00848165 |
| H2AZ1 | H2A.Z variant histone 1 | 0.00846593 |
| GLO1 | glyoxalase I | 0.00844259 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00843888 |
| RPA3 | replication protein A3, 14kDa | 0.00840572 |
| HMGB3 | high mobility group box 3 | 0.00836928 |
| ELP1 | elongator acetyltransferase complex subunit 1 | 0.00836874 |
| DENND2B | DENN domain containing 2B | 0.00834488 |
| THAP12 | THAP domain containing 12 | 0.00823975 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00823657 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00823315 |
| CNN3 | calponin 3, acidic | 0.00822386 |
| RANBP1 | RAN binding protein 1 | 0.00820918 |
| DHFR | dihydrofolate reductase | 0.00820022 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.00817758 |
| TRIB2 | tribbles pseudokinase 2 | 0.00817209 |
| PRMT1 | protein arginine methyltransferase 1 | 0.00816133 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 0.00813975 |
| MMP12 | matrix metallopeptidase 12 | 0.00812334 |
| S100A9 | S100 calcium binding protein A9 | 0.00810465 |
| GRAMD4 | GRAM domain containing 4 | 0.00809049 |
| LMNB1 | lamin B1 | 0.00807733 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00801945 |
| PMP22 | peripheral myelin protein 22 | 0.00800635 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.0080021 |
| NDUFA6 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa | 0.00800165 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | 0.00798428 |
| S100A8 | S100 calcium binding protein A8 | 0.00793487 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.00791742 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) | 0.0079037 |
| TSPAN6 | tetraspanin 6 | 0.00788761 |
| GLUL | glutamate-ammonia ligase | 0.00786947 |
| CD14 | CD14 molecule | 0.00785782 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00785163 |
| UBE2M | ubiquitin-conjugating enzyme E2M | 0.00782324 |
| EML3 | echinoderm microtubule associated protein like 3 | 0.0078036 |
| SELENOF | selenoprotein F | 0.00773711 |
| EFNB2 | ephrin-B2 | 0.00772991 |
| ANGPT1 | angiopoietin 1 | 0.00770931 |
| TSPAN5 | tetraspanin 5 | 0.00768471 |
| NPR3 | natriuretic peptide receptor 3 | 0.0076742 |
| NREP | neuronal regeneration related protein | 0.00766165 |
| TPM4 | tropomyosin 4 | 0.00764005 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.00762252 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0076184 |
| MCM6 | minichromosome maintenance complex component 6 | 0.00761778 |
| FJX1 | four jointed box 1 (Drosophila) | 0.0076093 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.00760644 |
| LRRC40 | leucine rich repeat containing 40 | 0.00759732 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.00756593 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.00756004 |
| MCM5 | minichromosome maintenance complex component 5 | 0.00753268 |
| CD2 | CD2 molecule | 0.00752267 |
| DCK | deoxycytidine kinase | 0.00751043 |
| TSPAN12 | tetraspanin 12 | 0.00747891 |
| RAD23A | RAD23 homolog A (S. cerevisiae) | 0.00747169 |
| KLHDC3 | kelch domain containing 3 | 0.00746711 |
| IPO5 | importin 5 | 0.00745974 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | 0.00745151 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | 0.00744392 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00744217 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.00744079 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | 0.00743691 |
| TK1 | thymidine kinase 1, soluble | 0.00743511 |
| ELP5 | elongator acetyltransferase complex subunit 5 | 0.00743074 |
| COL1A2 | collagen, type I, alpha 2 | 0.00738788 |
| GSAP | gamma-secretase activating protein | 0.00738439 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | 0.00736053 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.00735774 |
| FEN1 | flap structure-specific endonuclease 1 | 0.0073338 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.00731943 |
| NYNRIN | NYN domain and retroviral integrase containing | 0.00728158 |
| SPRR1B | small proline-rich protein 1B | 0.00728137 |
| CD300A | CD300a molecule | 0.00727994 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00727846 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00727111 |
| BRIX1 | BRX1, biogenesis of ribosomes | 0.00727021 |
| LSP1 | lymphocyte-specific protein 1 | 0.00725639 |
| TNC | tenascin C | 0.00723988 |
| KIAA0125 | KIAA0125 | 0.00722303 |
| BSG | basigin (Ok blood group) | 0.007208 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00719978 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00719858 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00719592 |
| KRT5 | keratin 5, type II | 0.00717797 |
| LBR | lamin B receptor | 0.00717315 |
| LOXL1 | lysyl oxidase-like 1 | 0.00716467 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00714249 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00711454 |
| HMGB1 | high mobility group box 1 | 0.00710149 |
| AURKB | aurora kinase B | 0.00710003 |
| TMED7 | transmembrane emp24 protein transport domain containing 7 | 0.00708978 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00705037 |
| SHOX2 | short stature homeobox 2 | 0.00704786 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | 0.00704703 |
| ACTL6A | actin-like 6A | 0.0070465 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | 0.00701942 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | 0.00701317 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.00700834 |
| ZNF274 | zinc finger protein 274 | 0.00699181 |
| PTK7 | protein tyrosine kinase 7 (inactive) | 0.00698207 |
| ZWINT | ZW10 interacting kinetochore protein | 0.00697917 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.00696632 |
| STMN1 | stathmin 1 | 0.0069581 |
| COPS4 | COP9 signalosome subunit 4 | 0.00694159 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | 0.00690102 |
| FAM234B | family with sequence similarity 234 member B | 0.00689525 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00689384 |
| CLEC7A | C-type lectin domain family 7, member A | 0.00687958 |
| CREB1 | cAMP responsive element binding protein 1 | 0.00685401 |
| CNTNAP2 | contactin associated protein-like 2 | 0.00683714 |
| MDFIC | MyoD family inhibitor domain containing | 0.00682049 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 0.00681312 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I | 0.00679448 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.00679063 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 0.0067636 |
| HDAC2 | histone deacetylase 2 | 0.00675889 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.00675239 |
| TTC38 | tetratricopeptide repeat domain 38 | 0.00674302 |
| CD164 | CD164 molecule, sialomucin | 0.00673744 |
| PCNXL4 | pecanex-like 4 (Drosophila) | 0.00673053 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.0067189 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00669886 |
| XYLT1 | xylosyltransferase I | 0.00669522 |
| NPTN | neuroplastin | 0.00668529 |
| EPHB3 | EPH receptor B3 | 0.0066677 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00666206 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.00666162 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.00664962 |
| TTC37 | tetratricopeptide repeat domain 37 | 0.00664477 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | 0.0066265 |
| HOXB2 | homeobox B2 | 0.00661728 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | 0.00661726 |
| HNMT | histamine N-methyltransferase | 0.00659546 |
| TMX1 | thioredoxin-related transmembrane protein 1 | 0.0065905 |
| ATP11B | ATPase, class VI, type 11B | 0.00657686 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.00657623 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.00657523 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00656919 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 | 0.00655402 |
| MCOLN1 | mucolipin 1 | 0.00653542 |
| MMP1 | matrix metallopeptidase 1 | 0.00652777 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00652667 |
| RRAGA | Ras-related GTP binding A | 0.00651445 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | 0.00650037 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.00649156 |
| CLCA1 | chloride channel accessory 1 | 0.006485 |
| SFN | stratifin | 0.00648302 |
| CCND2 | cyclin D2 | 0.00647709 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0064675 |
| TIMM17A | translocase of inner mitochondrial membrane 17 homolog A (yeast) | 0.00645342 |
| ACTN4 | actinin, alpha 4 | 0.00645318 |
| MAP7 | microtubule-associated protein 7 | 0.00645053 |
| NAGA | N-acetylgalactosaminidase, alpha- | 0.00644046 |
| F2R | coagulation factor II (thrombin) receptor | 0.00643545 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.0064295 |
| CDC20 | cell division cycle 20 | 0.00641868 |
| CHKB | choline kinase beta | 0.00638149 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00637191 |
| DMPK | dystrophia myotonica-protein kinase | 0.00631815 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | 0.00631459 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | 0.00629818 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 0.0062959 |
| PTTG1 | pituitary tumor-transforming 1 | 0.00628925 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | 0.00627382 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.00627211 |
| CA9 | carbonic anhydrase IX | 0.00627182 |
| RAB27A | RAB27A, member RAS oncogene family | 0.00624358 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 0.0062416 |
| ANGEL2 | angel homolog 2 (Drosophila) | 0.0062403 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | 0.00622846 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.00622138 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.00621503 |
| SMAD7 | SMAD family member 7 | 0.00621444 |
| CD8A | CD8a molecule | 0.00621256 |
| SPART | spartin | 0.00620568 |
| CD9 | CD9 molecule | 0.00619448 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 | 0.00618851 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 | 0.00618476 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | -0.0291114 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.0196966 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0173609 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0170903 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0165646 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0151681 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0151173 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0148775 |
| ANXA1 | annexin A1 | -0.0147841 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.0139642 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.0137529 |
| ATF3 | activating transcription factor 3 | -0.0136982 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | -0.0136811 |
| EPCAM | epithelial cell adhesion molecule | -0.0136105 |
| MT1X | metallothionein 1X | -0.0134794 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0134632 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0134046 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.0132909 |
| TFF1 | trefoil factor 1 | -0.0129483 |
| MX1 | MX dynamin-like GTPase 1 | -0.0128046 |
| HSPB8 | heat shock 22kDa protein 8 | -0.0127225 |
| LCN2 | lipocalin 2 | -0.0125292 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.012516 |
| ADD3 | adducin 3 (gamma) | -0.0124922 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.0124564 |
| VNN1 | vanin 1 | -0.0122025 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.0122002 |
| FGF13 | fibroblast growth factor 13 | -0.0118946 |
| MT1F | metallothionein 1F | -0.0117823 |
| ADIRF | adipogenesis regulatory factor | -0.0117339 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.0117297 |
| TSPAN8 | tetraspanin 8 | -0.0117033 |
| RPS27L | ribosomal protein S27-like | -0.0115911 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.0115125 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.0114926 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0114868 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.0114559 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0114485 |
| DEFB1 | defensin, beta 1 | -0.0114134 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.011266 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.0112584 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0112324 |
| RNASET2 | ribonuclease T2 | -0.0110505 |
| TAC1 | tachykinin, precursor 1 | -0.0110113 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.0110077 |
| STC2 | stanniocalcin 2 | -0.0109787 |
| STC1 | stanniocalcin 1 | -0.0107557 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0107167 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0106958 |
| CRYAB | crystallin, alpha B | -0.0106507 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0106208 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.0106197 |
| S100P | S100 calcium binding protein P | -0.0106087 |
| LAMP1 | lysosomal-associated membrane protein 1 | -0.0105692 |
| MT1G | metallothionein 1G | -0.010531 |
| MGLL | monoglyceride lipase | -0.0104616 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0104413 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0103803 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.010354 |
| SP110 | SP110 nuclear body protein | -0.0102768 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0102738 |
| SMAD3 | SMAD family member 3 | -0.0102122 |
| GPM6B | glycoprotein M6B | -0.010202 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.0101743 |
| G0S2 | G0/G1 switch 2 | -0.0101601 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0101581 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.0101253 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.0100993 |
| RRAGD | Ras-related GTP binding D | -0.0100783 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0100703 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.010063 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0100571 |
| CFD | complement factor D (adipsin) | -0.00992929 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00989444 |
| RND3 | Rho family GTPase 3 | -0.00986091 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00982599 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00982278 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00980419 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00979338 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00978757 |
| MT1H | metallothionein 1H | -0.00978696 |
| TOB1 | transducer of ERBB2, 1 | -0.00967678 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00964809 |
| SERINC5 | serine incorporator 5 | -0.00962312 |
| TRIM22 | tripartite motif containing 22 | -0.00961701 |
| IL6 | interleukin 6 | -0.00956776 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00956683 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00956102 |
| MT1M | metallothionein 1M | -0.00952776 |
| MYO1C | myosin IC | -0.00952143 |
| PLA1A | phospholipase A1 member A | -0.0095199 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00950043 |
| MFAP3L | microfibrillar-associated protein 3-like | -0.0094184 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.00938633 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00934857 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00933924 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00930728 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | -0.00930134 |
| SP100 | SP100 nuclear antigen | -0.00928583 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00927813 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.00927755 |
| CCN2 | cellular communication network factor 2 | -0.00927308 |
| MT2A | metallothionein 2A | -0.00926675 |
| PROM1 | prominin 1 | -0.00923465 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.00915702 |
| ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | -0.00915353 |
| ANXA3 | annexin A3 | -0.00914997 |
| ASS1 | argininosuccinate synthase 1 | -0.0091093 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.00908234 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | -0.00904113 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00897832 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.00896767 |
| AREG | amphiregulin | -0.00892398 |
| RPS26 | ribosomal protein S26 | -0.00892377 |
| ODC1 | ornithine decarboxylase 1 | -0.00891168 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00890137 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.00889539 |
| MVP | major vault protein | -0.00889378 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00889036 |
| TSC22D1 | TSC22 domain family, member 1 | -0.00887733 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00886716 |
| S100A10 | S100 calcium binding protein A10 | -0.00885619 |
| HMGA1 | high mobility group AT-hook 1 | -0.00879871 |
| EGR1 | early growth response 1 | -0.00877781 |
| LAMC2 | laminin, gamma 2 | -0.00876517 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.00875759 |
| OGA | O-GlcNAcase | -0.00874428 |
| INAVA | innate immunity activator | -0.00874373 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.00872863 |
| DAXX | death-domain associated protein | -0.00868915 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 | -0.00868244 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.00865873 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00865361 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -0.00861497 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00860042 |
| IER5 | immediate early response 5 | -0.00859276 |
| SELE | selectin E | -0.00858512 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00854068 |
| TTC39A | tetratricopeptide repeat domain 39A | -0.00853094 |
| ZNF165 | zinc finger protein 165 | -0.00848051 |
| CAB39 | calcium binding protein 39 | -0.00847589 |
| TP53I3 | tumor protein p53 inducible protein 3 | -0.00844791 |
| PRR13 | proline rich 13 | -0.00842447 |
| FAM111A | family with sequence similarity 111, member A | -0.00842142 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.0084204 |
| C6ORF48 | chromosome 6 open reading frame 48 | -0.00841319 |
| CFB | complement factor B | -0.00841033 |
| LINC00623 | long intergenic non-protein coding RNA 623 | -0.00840327 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.00836482 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.00834938 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00834916 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00830352 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.00829842 |
| MTIF2 | mitochondrial translational initiation factor 2 | -0.00826798 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | -0.00823971 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -0.00823257 |
| MYO1B | myosin IB | -0.00820276 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.0081547 |
| SARAF | store-operated calcium entry-associated regulatory factor | -0.00814391 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.00814064 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.00811649 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -0.00811617 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00808844 |
| MID1IP1 | MID1 interacting protein 1 | -0.00807814 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.00807208 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0080468 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.00798764 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00798589 |
| XBP1 | X-box binding protein 1 | -0.00796248 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0079402 |
| S100A11 | S100 calcium binding protein A11 | -0.00793456 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0079296 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.00792493 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.00789921 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.00788177 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | -0.00787572 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00783473 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00783384 |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 | -0.00783026 |
| DOCK9 | dedicator of cytokinesis 9 | -0.00782842 |
| FA2H | fatty acid 2-hydroxylase | -0.00779829 |
| HOMER1 | homer scaffolding protein 1 | -0.00779605 |
| PRSS3 | protease, serine, 3 | -0.00778341 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | -0.00776751 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | -0.00776646 |
| MALT1 | MALT1 paracaspase | -0.00776469 |
| NPTX2 | neuronal pentraxin II | -0.00776007 |
| TGFA | transforming growth factor, alpha | -0.00774693 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.00768946 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.0076858 |
| L1CAM | L1 cell adhesion molecule | -0.0076758 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | -0.00766695 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.00766236 |
| HMOX1 | heme oxygenase 1 | -0.00765903 |
| LEFTY1 | left-right determination factor 1 | -0.00764467 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00764398 |
| NUDC | nudC nuclear distribution protein | -0.00762802 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00756968 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.00754374 |
| PLLP | plasmolipin | -0.00753392 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.00752931 |
| MFSD1 | major facilitator superfamily domain containing 1 | -0.00752852 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | -0.00750212 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00745918 |
| CALB1 | calbindin 1, 28kDa | -0.00745875 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.00743628 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00743446 |
| ARL4A | ADP-ribosylation factor-like 4A | -0.00742195 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -0.00741404 |
| OFD1 | oral-facial-digital syndrome 1 | -0.00740385 |
| WDR45 | WD repeat domain 45 | -0.00740197 |
| LY75 | lymphocyte antigen 75 | -0.00739058 |
| BID | BH3 interacting domain death agonist | -0.00738081 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.0073695 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | -0.00736371 |
| RBM34 | RNA binding motif protein 34 | -0.00734128 |
| CCNG1 | cyclin G1 | -0.00733313 |
| SYT1 | synaptotagmin I | -0.00732957 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | -0.00732618 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.0072933 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00729224 |
| MSLN | mesothelin | -0.00728191 |
| ZNF423 | zinc finger protein 423 | -0.00727274 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00726775 |
| EGR3 | early growth response 3 | -0.00726311 |
| ICAM2 | intercellular adhesion molecule 2 | -0.00725558 |
| SQSTM1 | sequestosome 1 | -0.00725286 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00724085 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00724039 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00723826 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.00723648 |
| VWF | von Willebrand factor | -0.00723461 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00722836 |
| IER3 | immediate early response 3 | -0.00722655 |
| HECA | headcase homolog (Drosophila) | -0.00719556 |
| CCND3 | cyclin D3 | -0.00716322 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.00715617 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -0.00715384 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00714571 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.00714346 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0071387 |
| NADSYN1 | NAD synthetase 1 | -0.00713813 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.00713787 |
| CH25H | cholesterol 25-hydroxylase | -0.0071376 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.00713423 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00713121 |
| ZBTB16 | zinc finger and BTB domain containing 16 | -0.00712327 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00711296 |
| MRPL18 | mitochondrial ribosomal protein L18 | -0.00711199 |
| XIC | X chromosome inactivation center | -0.00710036 |
