| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled|The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.[supplied by OMIM, Oct 2009] (NCBI Entrez Gene Database, 3351) |
| External Link | https://ncbi.nlm.nih.gov/gene/3351 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the HTR1B gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HOXC6 | homeobox C6 | 0.0184001 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0181166 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0178111 |
| OLFM1 | olfactomedin 1 | 0.0152132 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0150215 |
| CA2 | carbonic anhydrase II | 0.0146711 |
| ADIRF | adipogenesis regulatory factor | 0.0145441 |
| METTL7A | methyltransferase like 7A | 0.0141853 |
| CFD | complement factor D (adipsin) | 0.0137151 |
| PRDX2 | peroxiredoxin 2 | 0.0136437 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.0133719 |
| CLU | clusterin | 0.0132794 |
| GAS1 | growth arrest-specific 1 | 0.0132206 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.0129346 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.0129301 |
| FASN | fatty acid synthase | 0.012864 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.0128122 |
| HBB | hemoglobin, beta | 0.0125931 |
| TXLNA | taxilin alpha | 0.0123894 |
| LYZ | lysozyme | 0.0122448 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0114978 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | 0.0113835 |
| FOXF1 | forkhead box F1 | 0.01126 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.0110761 |
| FADS1 | fatty acid desaturase 1 | 0.0110591 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.0110317 |
| NFIB | nuclear factor I/B | 0.010838 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0107816 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0107477 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0105148 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0104852 |
| FANCI | Fanconi anemia, complementation group I | 0.010477 |
| MT1E | metallothionein 1E | 0.010475 |
| TMSB15A | thymosin beta 15a | 0.0103608 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0102308 |
| HELLS | helicase, lymphoid-specific | 0.0102139 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0102109 |
| RAPSN | receptor-associated protein of the synapse | 0.0101434 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0101333 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.0100863 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0100181 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00988768 |
| SDC2 | syndecan 2 | 0.00982982 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00982048 |
| RGS5 | regulator of G-protein signaling 5 | 0.00978515 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00976663 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.00962289 |
| COL3A1 | collagen, type III, alpha 1 | 0.00957953 |
| KIF14 | kinesin family member 14 | 0.00954215 |
| CHN1 | chimerin 1 | 0.00952816 |
| TFDP1 | transcription factor Dp-1 | 0.00951539 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00945241 |
| TUBGCP3 | tubulin, gamma complex associated protein 3 | 0.00942761 |
| NTS | neurotensin | 0.00936324 |
| ACKR3 | atypical chemokine receptor 3 | 0.00932768 |
| GTSE1 | G-2 and S-phase expressed 1 | 0.00932462 |
| CD93 | CD93 molecule | 0.00932412 |
| RTN2 | reticulon 2 | 0.0092711 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0092193 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | 0.00919692 |
| LIG1 | ligase I, DNA, ATP-dependent | 0.00911979 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.00908949 |
| PTCH1 | patched 1 | 0.00907938 |
| NAA40 | N(alpha)-acetyltransferase 40, NatD catalytic subunit | 0.00906221 |
| KIF20A | kinesin family member 20A | 0.00903092 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 0.00900594 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00900554 |
| CFH | complement factor H | 0.00895736 |
| CDCA4 | cell division cycle associated 4 | 0.0088689 |
| CTBP1 | C-terminal binding protein 1 | 0.00886621 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 0.00886116 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00883426 |
| PCDH17 | protocadherin 17 | 0.00881787 |
| NUP85 | nucleoporin 85kDa | 0.00880332 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | 0.008791 |
| TNC | tenascin C | 0.00876209 |
| FBLN2 | fibulin 2 | 0.00871785 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00870797 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.00864452 |
| NID1 | nidogen 1 | 0.00863643 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00856774 |
| PLTP | phospholipid transfer protein | 0.00855532 |
| VWF | von Willebrand factor | 0.00855047 |
| KIF18B | kinesin family member 18B | 0.00854645 |
| TSPAN12 | tetraspanin 12 | 0.00853557 |
| PRC1 | protein regulator of cytokinesis 1 | 0.00851582 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00850416 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00849685 |
| SEPTIN10 | septin 10 | 0.00849413 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00848672 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.00848254 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.0084587 |
| EVA1B | eva-1 homolog B (C. elegans) | 0.00841626 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00836585 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 0.0083095 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 | 0.00830298 |
| PBK | PDZ binding kinase | 0.00829466 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.00828613 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.00823703 |
| FAM13A | family with sequence similarity 13, member A | 0.00822803 |
| MDFIC | MyoD family inhibitor domain containing | 0.0081713 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.00816143 |
| LHFP | lipoma HMGIC fusion partner | 0.00814534 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00812526 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.00812248 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | 0.00810965 |
| XK | X-linked Kx blood group | 0.00807313 |
| CCNF | cyclin F | 0.00806883 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.00806621 |
| RAD9A | RAD9 homolog A (S. pombe) | 0.00805098 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00804441 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.00802512 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00801311 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00800679 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00799203 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00798981 |
| POGLUT2 | protein O-glucosyltransferase 2 | 0.00798709 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 0.00798174 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.00792946 |
| FBXO21 | F-box protein 21 | 0.0079083 |
| GOLGA8A | golgin A8 family, member A | 0.00787274 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00786788 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.00784985 |
| OIP5 | Opa interacting protein 5 | 0.00783165 |
| HHEX | hematopoietically expressed homeobox | 0.007831 |
| GAA | glucosidase, alpha; acid | 0.00780269 |
| RAD51AP1 | RAD51 associated protein 1 | 0.00779798 |
| CDC7 | cell division cycle 7 | 0.00778142 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00777802 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | 0.00777296 |
| NLGN4X | neuroligin 4, X-linked | 0.00776628 |
| INSR | insulin receptor | 0.00775596 |
| KIAA0232 | KIAA0232 | 0.00774922 |
| CPE | carboxypeptidase E | 0.00773706 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | 0.00772874 |
| E2F8 | E2F transcription factor 8 | 0.00772516 |
| MT1F | metallothionein 1F | 0.00772269 |
| NEMP1 | nuclear envelope integral membrane protein 1 | 0.00771859 |
| KAZN | kazrin, periplakin interacting protein | 0.00769483 |
| ASF1B | anti-silencing function 1B histone chaperone | 0.00769298 |
| CIRBP | cold inducible RNA binding protein | 0.00768972 |
| FBXO5 | F-box protein 5 | 0.00767507 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 | 0.00767162 |
| PCOLCE | procollagen C-endopeptidase enhancer | 0.00766365 |
| PLK1 | polo-like kinase 1 | 0.00765778 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00764724 |
| ELAC2 | elaC ribonuclease Z 2 | 0.00764418 |
| RUVBL1 | RuvB-like AAA ATPase 1 | 0.00763522 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00762917 |
| PLXNB1 | plexin B1 | 0.00760278 |
| CD320 | CD320 molecule | 0.00759476 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00758382 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 0.0075644 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 | 0.00755676 |
| FANCG | Fanconi anemia, complementation group G | 0.00754798 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | 0.00753853 |
| CCL21 | chemokine (C-C motif) ligand 21 | 0.00750698 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.00748621 |
| CEP170 | centrosomal protein 170kDa | 0.00748618 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | 0.00748495 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | 0.00748043 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.00747876 |
| PHKA2 | phosphorylase kinase, alpha 2 (liver) | 0.00745108 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00744289 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.00734654 |
| AXL | AXL receptor tyrosine kinase | 0.00734188 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00733093 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F | 0.00730669 |
| LAMA5 | laminin, alpha 5 | 0.0073018 |
| B3GNT1 | 0.00729956 | |
| CD302 | CD302 molecule | 0.00729743 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00727009 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 | 0.00726884 |
| ABHD3 | abhydrolase domain containing 3 | 0.00726028 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00725827 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.0072451 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00723448 |
| SUZ12 | SUZ12 polycomb repressive complex 2 subunit | 0.00722426 |
| MAB21L2 | mab-21-like 2 (C. elegans) | 0.00721418 |
| CEP43 | centrosomal protein 43 | 0.0071887 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.0071885 |
| C8ORF33 | chromosome 8 open reading frame 33 | 0.00718072 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00718048 |
| CST3 | cystatin C | 0.00717396 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | 0.00717196 |
| NMU | neuromedin U | 0.0071694 |
| MACROD1 | MACRO domain containing 1 | 0.00715142 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) | 0.00713737 |
| CREBZF | CREB/ATF bZIP transcription factor | 0.00712865 |
| BAD | BCL2-associated agonist of cell death | 0.00712295 |
| RBBP4 | retinoblastoma binding protein 4 | 0.00710332 |
| CBR3 | carbonyl reductase 3 | 0.00708665 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.00708062 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.00706887 |
| ARGLU1 | arginine and glutamate rich 1 | 0.00706116 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.00705629 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00705046 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.00704491 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | 0.0070334 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.00703264 |
| NUP107 | nucleoporin 107kDa | 0.00698572 |
| RMI1 | RecQ mediated genome instability 1 | 0.00698041 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.00696762 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.00695907 |
| PROCR | protein C receptor, endothelial | 0.00692787 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.00692364 |
| NBEA | neurobeachin | 0.00691436 |
| SDC3 | syndecan 3 | 0.00690388 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal | 0.00690075 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | 0.00688976 |
| SRGN | serglycin | 0.00687339 |
| GOLM1 | golgi membrane protein 1 | 0.00687195 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.0068707 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.00685354 |
| NUP153 | nucleoporin 153kDa | 0.00685238 |
| PCNA | proliferating cell nuclear antigen | 0.00685004 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.00683299 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00682288 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | 0.00681916 |
| ISYNA1 | inositol-3-phosphate synthase 1 | 0.00681526 |
| NCAPG | non-SMC condensin I complex, subunit G | 0.00681283 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | 0.00680064 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 | 0.00678693 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00678632 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00678624 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.00678055 |
| JADE1 | jade family PHD finger 1 | 0.00677816 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00675866 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00675862 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 0.00674478 |
| MCM5 | minichromosome maintenance complex component 5 | 0.00674031 |
| MELK | maternal embryonic leucine zipper kinase | 0.00673936 |
| CYC1 | cytochrome c-1 | 0.00672954 |
| COL4A2 | collagen, type IV, alpha 2 | 0.00672435 |
| TMPO | thymopoietin | 0.00672384 |
| KIF23 | kinesin family member 23 | 0.00671876 |
| PAQR4 | progestin and adipoQ receptor family member IV | 0.0067018 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 0.00669997 |
| AZF1 | azoospermia factor 1 | 0.00669664 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) | 0.00668459 |
| TLCD3A | TLC domain containing 3A | 0.00668386 |
| SDF4 | stromal cell derived factor 4 | 0.00668285 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 0.00667041 |
| SYNM | synemin, intermediate filament protein | 0.00667012 |
| RUFY3 | RUN and FYVE domain containing 3 | 0.00666646 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00666628 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.00665527 |
| NHLRC2 | NHL repeat containing 2 | 0.00665202 |
| REV1 | REV1, polymerase (DNA directed) | 0.00663083 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00661225 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LTF | lactotransferrin | -0.029997 |
| LCN2 | lipocalin 2 | -0.0181264 |
| XIC | X chromosome inactivation center | -0.0175018 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0159924 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0156999 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.0143615 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0141724 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0134707 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0133673 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0133223 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0132671 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -0.0127458 |
| HTRA1 | HtrA serine peptidase 1 | -0.0126095 |
| CTSD | cathepsin D | -0.0124559 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0123384 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0123189 |
| KRT15 | keratin 15, type I | -0.0122149 |
| TP53I3 | tumor protein p53 inducible protein 3 | -0.0119498 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.0118855 |
| S100A9 | S100 calcium binding protein A9 | -0.0118328 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.0117122 |
| MAL | mal, T-cell differentiation protein | -0.0116975 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.0116064 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.0115355 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.011311 |
| S100A8 | S100 calcium binding protein A8 | -0.0112966 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0112304 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.011181 |
| ANXA1 | annexin A1 | -0.0110197 |
| FOSL2 | FOS-like antigen 2 | -0.0109582 |
| CD9 | CD9 molecule | -0.0109292 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.0109272 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.0108131 |
| INHBA | inhibin, beta A | -0.0107299 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0107266 |
| KRT14 | keratin 14, type I | -0.0106042 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.0104726 |
| KRT5 | keratin 5, type II | -0.010453 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0104363 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.0104335 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | -0.0102922 |
| HDAC9 | histone deacetylase 9 | -0.0102889 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0102027 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0101546 |
| EMP1 | epithelial membrane protein 1 | -0.0100253 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0100063 |
| PITX3 | paired-like homeodomain 3 | -0.00995584 |
| PLAUR | plasminogen activator, urokinase receptor | -0.00993851 |
| NRCAM | neuronal cell adhesion molecule | -0.00992414 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00991783 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | -0.00991542 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00990369 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.00986909 |
| EGR2 | early growth response 2 | -0.00986878 |
| IER5 | immediate early response 5 | -0.00978439 |
| COG7 | component of oligomeric golgi complex 7 | -0.00974944 |
| MMP8 | matrix metallopeptidase 8 | -0.00971993 |
| COCH | cochlin | -0.00963743 |
| CSTB | cystatin B (stefin B) | -0.00963346 |
| ZIC1 | Zic family member 1 | -0.00954609 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.00953223 |
| CLTB | clathrin, light chain B | -0.00952836 |
| IPO13 | importin 13 | -0.00950511 |
| CST7 | cystatin F (leukocystatin) | -0.00946818 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | -0.0094644 |
| MLPH | melanophilin | -0.00946101 |
| CAPN3 | calpain 3, (p94) | -0.00946067 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0093697 |
| IFI44 | interferon-induced protein 44 | -0.0093379 |
| IL2RG | interleukin 2 receptor, gamma | -0.00932601 |
| TARP | TCR gamma alternate reading frame protein | -0.00929577 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00927959 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00927507 |
| DSP | desmoplakin | -0.00925483 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.0092514 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00922926 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00922324 |
| BPI | bactericidal/permeability-increasing protein | -0.00920844 |
| FABP7 | fatty acid binding protein 7, brain | -0.00914106 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | -0.00911798 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00911059 |
| RGS10 | regulator of G-protein signaling 10 | -0.00909013 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00906968 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00904422 |
| SORT1 | sortilin 1 | -0.00904188 |
| BCL2A1 | BCL2-related protein A1 | -0.00899922 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.00897016 |
| ATF3 | activating transcription factor 3 | -0.00893094 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.00890725 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00887834 |
| PODXL | podocalyxin-like | -0.00883409 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00883103 |
| OPTN | optineurin | -0.00881284 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | -0.00877419 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00873143 |
| SCG5 | secretogranin V | -0.00872694 |
| THBS2 | thrombospondin 2 | -0.00865071 |
| JMJD6 | jumonji domain containing 6 | -0.00863391 |
| PRSS23 | protease, serine, 23 | -0.00857208 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | -0.00853912 |
| PDLIM1 | PDZ and LIM domain 1 | -0.00851022 |
| GRN | granulin | -0.00850834 |
| KRT6A | keratin 6A, type II | -0.00850004 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | -0.00849362 |
| CHI3L2 | chitinase 3-like 2 | -0.00849248 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00848135 |
| S100A7 | S100 calcium binding protein A7 | -0.00847741 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00844681 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -0.00840633 |
| CRYAB | crystallin, alpha B | -0.0083992 |
| LSP1 | lymphocyte-specific protein 1 | -0.00834522 |
| MZB1 | marginal zone B and B1 cell-specific protein | -0.00834508 |
| CORO1A | coronin, actin binding protein, 1A | -0.00833255 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.00832125 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | -0.00830145 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00821646 |
| GLRX | glutaredoxin (thioltransferase) | -0.00819615 |
| CLDN7 | claudin 7 | -0.00816262 |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | -0.00815261 |
| CLDN8 | claudin 8 | -0.00815223 |
| SNAI2 | snail family zinc finger 2 | -0.00812625 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00810191 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | -0.00809509 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | -0.00809337 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.00807029 |
| STK38L | serine/threonine kinase 38 like | -0.00802526 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00800467 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.00798867 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00794906 |
| PRKCH | protein kinase C, eta | -0.00794439 |
| KRT81 | keratin 81, type II | -0.00790246 |
| CSTA | cystatin A (stefin A) | -0.00789049 |
| REEP5 | receptor accessory protein 5 | -0.00787906 |
| VLDLR | very low density lipoprotein receptor | -0.00786556 |
| IFRD1 | interferon-related developmental regulator 1 | -0.00784949 |
| BAX | BCL2-associated X protein | -0.00784693 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00784515 |
| IL1RN | interleukin 1 receptor antagonist | -0.00783967 |
| RRAGD | Ras-related GTP binding D | -0.00781586 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.00780244 |
| S100A10 | S100 calcium binding protein A10 | -0.00779749 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00777665 |
| PFKP | phosphofructokinase, platelet | -0.00777265 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.00775753 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.00772893 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00771178 |
| DNTT | DNA nucleotidylexotransferase | -0.0076939 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 | -0.00768261 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00765824 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | -0.00763328 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00761714 |
| CDA | cytidine deaminase | -0.00761332 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00761132 |
| POSTN | periostin, osteoblast specific factor | -0.00760182 |
| LTA4H | leukotriene A4 hydrolase | -0.00759863 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.0075613 |
| ANXA11 | annexin A11 | -0.00755817 |
| SARS1 | seryl-tRNA synthetase 1 | -0.00753453 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | -0.00752986 |
| MMP7 | matrix metallopeptidase 7 | -0.00751553 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.00749437 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00748193 |
| NVL | nuclear VCP-like | -0.00747898 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00744482 |
| LINC00623 | long intergenic non-protein coding RNA 623 | -0.00744111 |
| MALL | mal, T-cell differentiation protein-like | -0.00743722 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00742973 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -0.00742498 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.00742383 |
| RHOC | ras homolog family member C | -0.00739728 |
| PDE4DIP | phosphodiesterase 4D interacting protein | -0.00739427 |
| LAMC2 | laminin, gamma 2 | -0.00738254 |
| PHF11 | PHD finger protein 11 | -0.00737168 |
| IFI35 | interferon-induced protein 35 | -0.00734815 |
| LPIN1 | lipin 1 | -0.00734591 |
| ATP5F1C | ATP synthase F1 subunit gamma | -0.0073435 |
| SH3BGR | SH3 domain binding glutamate-rich protein | -0.00733441 |
| RGS4 | regulator of G-protein signaling 4 | -0.00731285 |
| AAMDC | adipogenesis associated, Mth938 domain containing | -0.00730686 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00726379 |
| IL32 | interleukin 32 | -0.00722473 |
| IFI44L | interferon-induced protein 44-like | -0.00719867 |
| CALB1 | calbindin 1, 28kDa | -0.00719683 |
| KYNU | kynureninase | -0.00719496 |
| GPN1 | GPN-loop GTPase 1 | -0.00719226 |
| ZNF365 | zinc finger protein 365 | -0.00719167 |
| KRT19 | keratin 19, type I | -0.00717739 |
| ATP6V1F | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | -0.0071569 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00715376 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00713816 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.00710827 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | -0.00710798 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.0071011 |
| GPM6B | glycoprotein M6B | -0.00709614 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00709243 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.00708772 |
| EREG | epiregulin | -0.00708563 |
| FOLR1 | folate receptor 1 (adult) | -0.00706641 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00706036 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00705608 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.00705545 |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | -0.00705524 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | -0.00704644 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00703123 |
| LY96 | lymphocyte antigen 96 | -0.00701426 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00700674 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00700486 |
| AOC1 | amine oxidase, copper containing 1 | -0.00698647 |
| LIF | leukemia inhibitory factor | -0.00698581 |
| KRT13 | keratin 13, type I | -0.00697286 |
| SP100 | SP100 nuclear antigen | -0.00697135 |
| ARF4 | ADP-ribosylation factor 4 | -0.00696124 |
| RGS17 | regulator of G-protein signaling 17 | -0.00694784 |
| PPA1 | pyrophosphatase (inorganic) 1 | -0.00693897 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.00693006 |
| UBASH3A | ubiquitin associated and SH3 domain containing A | -0.0069261 |
| YME1L1 | YME1-like 1 ATPase | -0.00691354 |
| CD177 | CD177 molecule | -0.00690336 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00688858 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.00688217 |
| AREG | amphiregulin | -0.0068747 |
| RTP4 | receptor (chemosensory) transporter protein 4 | -0.00687367 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00687145 |
| GSTO1 | glutathione S-transferase omega 1 | -0.00687105 |
| PARD3 | par-3 family cell polarity regulator | -0.00684368 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -0.00682804 |
| DUSP2 | dual specificity phosphatase 2 | -0.00678806 |
| PADI2 | peptidyl arginine deiminase, type II | -0.0067694 |
| LGMN | legumain | -0.00676554 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.00676223 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00674637 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00673991 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00673513 |
| CA8 | carbonic anhydrase VIII | -0.00673343 |
| CAMP | cathelicidin antimicrobial peptide | -0.00672194 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.0067204 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | -0.00671905 |
| ATP6V1E1 | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 | -0.0067188 |
| PTHLH | parathyroid hormone-like hormone | -0.00671369 |
| GPR65 | G protein-coupled receptor 65 | -0.00671275 |
| JUNB | jun B proto-oncogene | -0.00668491 |
| ACP1 | acid phosphatase 1, soluble | -0.0066448 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00664189 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.00662854 |
| TRAF3IP2 | TRAF3 interacting protein 2 | -0.00662804 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00661657 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.00661546 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | -0.0066153 |
| USP18 | ubiquitin specific peptidase 18 | -0.00660576 |
| KLF6 | Kruppel-like factor 6 | -0.00660057 |
