| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic|The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3359) |
| External Link | https://ncbi.nlm.nih.gov/gene/3359 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the HTR3A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NRN1 | neuritin 1 | 0.0113769 |
| MAOA | monoamine oxidase A | 0.0098538 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00958109 |
| HBB | hemoglobin, beta | 0.00938873 |
| HOXC6 | homeobox C6 | 0.00907955 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00876043 |
| FABP1 | fatty acid binding protein 1, liver | 0.00873776 |
| PLK1 | polo-like kinase 1 | 0.00817563 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00806087 |
| PRAME | preferentially expressed antigen in melanoma | 0.00798882 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.0079512 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.0078872 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.00783273 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00776243 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.0077379 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00766211 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00757635 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00754332 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | 0.00750487 |
| RETREG1 | reticulophagy regulator 1 | 0.00748832 |
| A2M | alpha-2-macroglobulin | 0.00741498 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.00739581 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 0.00738844 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.00738228 |
| CDC45 | cell division cycle 45 | 0.00733523 |
| HOMER2 | homer scaffolding protein 2 | 0.00727002 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.00726618 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | 0.00722854 |
| NID1 | nidogen 1 | 0.00711256 |
| L1CAM | L1 cell adhesion molecule | 0.00709739 |
| NPY1R | neuropeptide Y receptor Y1 | 0.0070892 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00703492 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00702718 |
| LYZ | lysozyme | 0.00700897 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00690432 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.0068877 |
| LIG1 | ligase I, DNA, ATP-dependent | 0.00683626 |
| SYNGR3 | synaptogyrin 3 | 0.00682357 |
| DHFR | dihydrofolate reductase | 0.00681503 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00671709 |
| FAM13A | family with sequence similarity 13, member A | 0.00666283 |
| PLN | phospholamban | 0.00661915 |
| MCAM | melanoma cell adhesion molecule | 0.00661711 |
| KRT20 | keratin 20, type I | 0.00659163 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00657003 |
| HELLS | helicase, lymphoid-specific | 0.00655665 |
| MELK | maternal embryonic leucine zipper kinase | 0.00653834 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00650227 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00649179 |
| RGS5 | regulator of G-protein signaling 5 | 0.00646991 |
| MAB21L2 | mab-21-like 2 (C. elegans) | 0.00646727 |
| ARG2 | arginase 2 | 0.00645799 |
| ASF1B | anti-silencing function 1B histone chaperone | 0.00635147 |
| TPM2 | tropomyosin 2 (beta) | 0.00629083 |
| NFIB | nuclear factor I/B | 0.00628398 |
| OPHN1 | oligophrenin 1 | 0.00626861 |
| GRB14 | growth factor receptor-bound protein 14 | 0.00625196 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00623829 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 0.0062333 |
| CCNE2 | cyclin E2 | 0.00622489 |
| GTSE1 | G-2 and S-phase expressed 1 | 0.00618121 |
| TNC | tenascin C | 0.00618077 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.00613424 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.00611871 |
| THYN1 | thymocyte nuclear protein 1 | 0.00611402 |
| AFF1 | AF4/FMR2 family, member 1 | 0.00608659 |
| SLC2A4RG | SLC2A4 regulator | 0.00608637 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.00600158 |
| GNAS | GNAS complex locus | 0.00596644 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00593365 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00593085 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0059107 |
| DMBT1 | deleted in malignant brain tumors 1 | 0.00588989 |
| SHCBP1 | SHC SH2-domain binding protein 1 | 0.00588196 |
| BARD1 | BRCA1 associated RING domain 1 | 0.00587863 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00587466 |
| NPTX2 | neuronal pentraxin II | 0.00586992 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00586296 |
| CFI | complement factor I | 0.0058543 |
| SELENOW | selenoprotein W | 0.0058441 |
| GPA33 | glycoprotein A33 (transmembrane) | 0.00583856 |
| KIFC1 | kinesin family member C1 | 0.00582967 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00582848 |
| HYOU1 | hypoxia up-regulated 1 | 0.00582313 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00579066 |
| VIM | vimentin | 0.00578032 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00575555 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00571246 |
| KIF20A | kinesin family member 20A | 0.00570839 |
| CRIP2 | cysteine-rich protein 2 | 0.00569245 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.0056373 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00562052 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00561759 |
| COL4A2 | collagen, type IV, alpha 2 | 0.00561284 |
| C7 | complement component 7 | 0.0055745 |
| SMC2 | structural maintenance of chromosomes 2 | 0.00556392 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00554753 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00554441 |
| KIF15 | kinesin family member 15 | 0.00554316 |
| NEMP1 | nuclear envelope integral membrane protein 1 | 0.00553641 |
| RUVBL1 | RuvB-like AAA ATPase 1 | 0.00552366 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00551996 |
| SVIL | supervillin | 0.00551546 |
| CENPE | centromere protein E, 312kDa | 0.00550458 |
| PTCH1 | patched 1 | 0.00548791 |
| CALD1 | caldesmon 1 | 0.00546063 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.00545904 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.00543794 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 0.00542674 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.0054196 |
| OIP5 | Opa interacting protein 5 | 0.005384 |
| RNF130 | ring finger protein 130 | 0.0053823 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.00536962 |
| TFDP1 | transcription factor Dp-1 | 0.00536488 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.00535294 |
| CENPF | centromere protein F, 350/400kDa | 0.00534924 |
| DEK | DEK proto-oncogene | 0.00532318 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | 0.00531658 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) | 0.00531269 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | 0.00530952 |
| PIMREG | PICALM interacting mitotic regulator | 0.00529894 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 0.00529023 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | 0.00528949 |
| PAIP2B | poly(A) binding protein interacting protein 2B | 0.00525809 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 0.0052515 |
| CIRBP | cold inducible RNA binding protein | 0.00524354 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00524146 |
| ESR1 | estrogen receptor 1 | 0.00523558 |
| LOXL2 | lysyl oxidase-like 2 | 0.00522485 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00521031 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.00516085 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0051554 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 0.00515038 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00512979 |
| MAL | mal, T-cell differentiation protein | 0.00512906 |
| TROAP | trophinin associated protein | 0.00509863 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.00509075 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.00508903 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00508382 |
| REEP1 | receptor accessory protein 1 | 0.00507904 |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 | 0.00507797 |
| FANCG | Fanconi anemia, complementation group G | 0.00506128 |
| GTF3A | general transcription factor IIIA | 0.0050581 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 0.00505427 |
| TPX2 | TPX2, microtubule-associated | 0.00505292 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00504566 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | 0.00503974 |
| CLCA1 | chloride channel accessory 1 | 0.00503479 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00503301 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00502763 |
| CBX5 | chromobox homolog 5 | 0.00502235 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 | 0.0050211 |
| RNF144A | ring finger protein 144A | 0.0050152 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00500385 |
| MCM10 | minichromosome maintenance complex component 10 | 0.00499339 |
| FANCI | Fanconi anemia, complementation group I | 0.00499203 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.00498924 |
| GRHPR | glyoxylate reductase/hydroxypyruvate reductase | 0.00496955 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00496766 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00496587 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 | 0.00495256 |
| FABP6 | fatty acid binding protein 6, ileal | 0.00495022 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.00494259 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.00494217 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 0.00494048 |
| PBK | PDZ binding kinase | 0.00493348 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | 0.00493327 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | 0.0049294 |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) | 0.00492538 |
| MYL9 | myosin, light chain 9, regulatory | 0.00492109 |
| POGLUT1 | protein O-glucosyltransferase 1 | 0.00491673 |
| OLFM4 | olfactomedin 4 | 0.00491351 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00489069 |
| TMEM204 | transmembrane protein 204 | 0.00485844 |
| SV2A | synaptic vesicle glycoprotein 2A | 0.00485785 |
| MARCO | macrophage receptor with collagenous structure | 0.00484485 |
| E2F8 | E2F transcription factor 8 | 0.00483941 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.0048361 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0048305 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.00482135 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00479084 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.00477999 |
| DGLUCY | D-glutamate cyclase | 0.00477728 |
| NCAPH | non-SMC condensin I complex, subunit H | 0.0047762 |
| RLN1 | relaxin 1 | 0.00475007 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | 0.00474702 |
| ADCY1 | adenylate cyclase 1 (brain) | 0.00474225 |
| ERGIC2 | ERGIC and golgi 2 | 0.00474146 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00473975 |
| TNS1 | tensin 1 | 0.00473951 |
| RAD54B | RAD54 homolog B (S. cerevisiae) | 0.00471956 |
| KIF18A | kinesin family member 18A | 0.00471194 |
| TMEM255A | transmembrane protein 255A | 0.00469284 |
| MSX1 | msh homeobox 1 | 0.00468032 |
| PHF20 | PHD finger protein 20 | 0.0046717 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00465495 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.00464609 |
| NUP85 | nucleoporin 85kDa | 0.00463731 |
| EXO1 | exonuclease 1 | 0.00462902 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00462206 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 | 0.00459637 |
| ACKR3 | atypical chemokine receptor 3 | 0.00458706 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | 0.00458506 |
| PLA2G12A | phospholipase A2, group XIIA | 0.00458186 |
| FN1 | fibronectin 1 | 0.00458062 |
| PLCB4 | phospholipase C, beta 4 | 0.00456533 |
| SRP9 | signal recognition particle 9kDa | 0.00456255 |
| CBX3 | chromobox homolog 3 | 0.00455698 |
| CCNF | cyclin F | 0.00455 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00454967 |
| KIF23 | kinesin family member 23 | 0.00454741 |
| ITM2C | integral membrane protein 2C | 0.00454736 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.00454611 |
| TRMT5 | tRNA methyltransferase 5 | 0.00453757 |
| RDX | radixin | 0.00452965 |
| SIVA1 | SIVA1, apoptosis-inducing factor | 0.00452836 |
| GRAMD1C | GRAM domain containing 1C | 0.00452735 |
| THOC2 | THO complex 2 | 0.00452321 |
| NNMT | nicotinamide N-methyltransferase | 0.00451817 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00451233 |
| PARP2 | poly (ADP-ribose) polymerase 2 | 0.00449845 |
| FKBP5 | FK506 binding protein 5 | 0.00449029 |
| SERINC5 | serine incorporator 5 | 0.00448797 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) | 0.00448376 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00448032 |
| HMGB1 | high mobility group box 1 | 0.0044713 |
| TMEM63A | transmembrane protein 63A | 0.00446203 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00445761 |
| SARAF | store-operated calcium entry-associated regulatory factor | 0.00445644 |
| ORC1 | origin recognition complex, subunit 1 | 0.00445384 |
| MTA1 | metastasis associated 1 | 0.0044537 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.00444104 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0044402 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00443827 |
| RAB20 | RAB20, member RAS oncogene family | 0.00443652 |
| SOX17 | SRY (sex determining region Y)-box 17 | 0.00442645 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00442541 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.00442136 |
| VANGL1 | VANGL planar cell polarity protein 1 | 0.00442 |
| VWF | von Willebrand factor | 0.00441876 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.00439761 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.00439384 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.00439092 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | 0.00438408 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) | 0.00437274 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00436697 |
| ERGIC3 | ERGIC and golgi 3 | 0.00436637 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00436061 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.00435925 |
| BRCA1 | breast cancer 1, early onset | 0.00435915 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0195488 |
| LTF | lactotransferrin | -0.0147539 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0144076 |
| LCN2 | lipocalin 2 | -0.0137546 |
| CSTA | cystatin A (stefin A) | -0.0126147 |
| KRT14 | keratin 14, type I | -0.0114604 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0112113 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.0111465 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.011064 |
| IER5 | immediate early response 5 | -0.0109762 |
| S100A9 | S100 calcium binding protein A9 | -0.0109614 |
| ASS1 | argininosuccinate synthase 1 | -0.0106234 |
| KRT19 | keratin 19, type I | -0.0104621 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.0104588 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.0103446 |
| KRT15 | keratin 15, type I | -0.010155 |
| HIST1H2BK | histone cluster 1, H2bk | -0.01015 |
| HIST1H2BD | histone cluster 1, H2bd | -0.0100049 |
| DSP | desmoplakin | -0.00996458 |
| IL1RN | interleukin 1 receptor antagonist | -0.00993501 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00983099 |
| DUSP5 | dual specificity phosphatase 5 | -0.00975488 |
| SFN | stratifin | -0.00965929 |
| S100A8 | S100 calcium binding protein A8 | -0.00965603 |
| HK1 | hexokinase 1 | -0.00963409 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00954648 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00948665 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00948441 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00944433 |
| CLDN10 | claudin 10 | -0.00939408 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00938025 |
| S100P | S100 calcium binding protein P | -0.00934174 |
| STC2 | stanniocalcin 2 | -0.00929907 |
| PLAU | plasminogen activator, urokinase | -0.0092458 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00917644 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00910988 |
| KRT5 | keratin 5, type II | -0.00910978 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00909022 |
| JUNB | jun B proto-oncogene | -0.0088448 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00877451 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00875625 |
| DUSP2 | dual specificity phosphatase 2 | -0.00870048 |
| KRT7 | keratin 7, type II | -0.00865108 |
| KRT23 | keratin 23, type I | -0.00861644 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00861469 |
| KRT6A | keratin 6A, type II | -0.00856614 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00853481 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00849119 |
| HOPX | HOP homeobox | -0.00842661 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00842631 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00842147 |
| ACOT9 | acyl-CoA thioesterase 9 | -0.0083979 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00834129 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00833957 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00825764 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.00821325 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00818184 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00816926 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00805261 |
| PTN | pleiotrophin | -0.00804602 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0079699 |
| TYMP | thymidine phosphorylase | -0.00791966 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00791435 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00789943 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00781153 |
| KLK11 | kallikrein-related peptidase 11 | -0.00777963 |
| EGR2 | early growth response 2 | -0.00773622 |
| MMP7 | matrix metallopeptidase 7 | -0.00770806 |
| TRIB2 | tribbles pseudokinase 2 | -0.00769945 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00768491 |
| LAMB3 | laminin, beta 3 | -0.00768117 |
| FGB | fibrinogen beta chain | -0.00764056 |
| TPSAB1 | tryptase alpha/beta 1 | -0.0076368 |
| RALB | v-ral simian leukemia viral oncogene homolog B | -0.0075662 |
| GPM6B | glycoprotein M6B | -0.00754954 |
| SCG5 | secretogranin V | -0.00754784 |
| RAB9A | RAB9A, member RAS oncogene family | -0.00752573 |
| MXRA5 | matrix-remodelling associated 5 | -0.00742419 |
| G0S2 | G0/G1 switch 2 | -0.00739187 |
| KLK10 | kallikrein-related peptidase 10 | -0.00738516 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.00736784 |
| S100A11 | S100 calcium binding protein A11 | -0.00735729 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00734553 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00733715 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00726499 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00724418 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00721886 |
| PERP | PERP, TP53 apoptosis effector | -0.00714192 |
| TSPO | translocator protein (18kDa) | -0.00714042 |
| KLF10 | Kruppel-like factor 10 | -0.0071364 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00710796 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.00710134 |
| PLK2 | polo-like kinase 2 | -0.00709792 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00709689 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00707809 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00707079 |
| CRYAB | crystallin, alpha B | -0.00706797 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00705978 |
| MLPH | melanophilin | -0.00705808 |
| CA12 | carbonic anhydrase XII | -0.00704483 |
| S100A14 | S100 calcium binding protein A14 | -0.00703086 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.00702011 |
| CFB | complement factor B | -0.0070134 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00700593 |
| KRT16 | keratin 16, type I | -0.00699813 |
| FGG | fibrinogen gamma chain | -0.00698832 |
| PLBD1 | phospholipase B domain containing 1 | -0.00697464 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.0069359 |
| HPGDS | hematopoietic prostaglandin D synthase | -0.00690614 |
| FABP7 | fatty acid binding protein 7, brain | -0.0068627 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00683812 |
| NAV3 | neuron navigator 3 | -0.00679061 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00678805 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0067805 |
| HDAC9 | histone deacetylase 9 | -0.00676649 |
| S100A7 | S100 calcium binding protein A7 | -0.00674282 |
| TRIM29 | tripartite motif containing 29 | -0.00673664 |
| CD69 | CD69 molecule | -0.00671781 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00671758 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.00671184 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00668731 |
| ATF3 | activating transcription factor 3 | -0.0066783 |
| ANXA1 | annexin A1 | -0.00664156 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00664022 |
| PKP1 | plakophilin 1 | -0.00659834 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.0065545 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00654856 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.00654429 |
| NRCAM | neuronal cell adhesion molecule | -0.00650776 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00648297 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00645573 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00644432 |
| ZC3H12A | zinc finger CCCH-type containing 12A | -0.00644391 |
| HIST1H2BH | histone cluster 1, H2bh | -0.00642172 |
| PAEP | progestagen-associated endometrial protein | -0.0064073 |
| LYPD3 | LY6/PLAUR domain containing 3 | -0.00640624 |
| DCN | decorin | -0.00639847 |
| CALB1 | calbindin 1, 28kDa | -0.00639289 |
| PRSS23 | protease, serine, 23 | -0.0063816 |
| KYNU | kynureninase | -0.00637974 |
| C1S | complement component 1, s subcomponent | -0.00635792 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00633894 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | -0.00633475 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00632516 |
| KLK6 | kallikrein-related peptidase 6 | -0.00632189 |
| COL5A2 | collagen, type V, alpha 2 | -0.00630648 |
| XYLT1 | xylosyltransferase I | -0.006287 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00628597 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00627277 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0062563 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -0.00618699 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | -0.00617236 |
| GM2A | GM2 ganglioside activator | -0.00613312 |
| CRCT1 | cysteine-rich C-terminal 1 | -0.00612929 |
| MX1 | MX dynamin-like GTPase 1 | -0.00612716 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | -0.00612281 |
| PPL | periplakin | -0.00610333 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00609 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00605247 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.00604997 |
| STK10 | serine/threonine kinase 10 | -0.00601703 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00600714 |
| TPST2 | tyrosylprotein sulfotransferase 2 | -0.00600245 |
| SNAI2 | snail family zinc finger 2 | -0.00598743 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00598305 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00598126 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00597526 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00590356 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0058918 |
| CTSD | cathepsin D | -0.00589097 |
| PLXNC1 | plexin C1 | -0.00586195 |
| TUFT1 | tuftelin 1 | -0.00585702 |
| ANGPT1 | angiopoietin 1 | -0.00584417 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.00582663 |
| FOSL2 | FOS-like antigen 2 | -0.00581595 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00581166 |
| REEP5 | receptor accessory protein 5 | -0.00578552 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -0.00578529 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.00575873 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.00573875 |
| NOTCH2 | notch 2 | -0.00573691 |
| INHBA | inhibin, beta A | -0.00573248 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00573032 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -0.00572335 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00569738 |
| RTP4 | receptor (chemosensory) transporter protein 4 | -0.00569216 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.00568555 |
| RABAC1 | Rab acceptor 1 (prenylated) | -0.00567765 |
| TP53I3 | tumor protein p53 inducible protein 3 | -0.00566177 |
| TUBA4A | tubulin, alpha 4a | -0.00565991 |
| AOC1 | amine oxidase, copper containing 1 | -0.00565602 |
| MMP19 | matrix metallopeptidase 19 | -0.00563068 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00561722 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.0056136 |
| MFAP3L | microfibrillar-associated protein 3-like | -0.00559825 |
| IRF7 | interferon regulatory factor 7 | -0.0055901 |
| IFRD1 | interferon-related developmental regulator 1 | -0.00558726 |
| SIK1 | salt-inducible kinase 1 | -0.00556801 |
| KRT17 | keratin 17, type I | -0.00556019 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00554775 |
| MRPS2 | mitochondrial ribosomal protein S2 | -0.00553951 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0055249 |
| MPC2 | mitochondrial pyruvate carrier 2 | -0.00552126 |
| H1-2 | H1.2 linker histone, cluster member | -0.00550403 |
| IL1B | interleukin 1, beta | -0.00550316 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.00550287 |
| INHBB | inhibin, beta B | -0.00549418 |
| RNF19B | ring finger protein 19B | -0.00549204 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) | -0.00548428 |
| CSTB | cystatin B (stefin B) | -0.00548037 |
| XIC | X chromosome inactivation center | -0.00547862 |
| RRAGD | Ras-related GTP binding D | -0.00547302 |
| AK1 | adenylate kinase 1 | -0.00546121 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00546109 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00545961 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00544176 |
| INAVA | innate immunity activator | -0.00542208 |
| GSR | glutathione reductase | -0.0054211 |
| EMP1 | epithelial membrane protein 1 | -0.00541982 |
| IRF9 | interferon regulatory factor 9 | -0.00541869 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00540579 |
| MOSPD1 | motile sperm domain containing 1 | -0.00540509 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00540378 |
| SQLE | squalene epoxidase | -0.0054014 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | -0.00538301 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | -0.00537949 |
| GFAP | glial fibrillary acidic protein | -0.00537917 |
| ANK2 | ankyrin 2, neuronal | -0.00537887 |
| SPRR2B | small proline-rich protein 2B | -0.00536258 |
| KRT6B | keratin 6B, type II | -0.00535722 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00535099 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00534238 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.00533851 |
| TCTA | T-cell leukemia translocation altered | -0.00533398 |
| UBE3C | ubiquitin protein ligase E3C | -0.00532477 |
| PITX3 | paired-like homeodomain 3 | -0.00531541 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | -0.00531028 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00531017 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00530435 |
| GPX2 | glutathione peroxidase 2 | -0.00530375 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00528588 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | -0.00526307 |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | -0.0052571 |
| AFTPH | aftiphilin | -0.00525412 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00524562 |
| NPC1 | Niemann-Pick disease, type C1 | -0.00523036 |
| DSG3 | desmoglein 3 | -0.00522933 |
| MAP7 | microtubule-associated protein 7 | -0.00522754 |
