| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | HUS1 checkpoint homolog (S. pombe)|The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011] (NCBI Entrez Gene Database, 3364) |
| External Link | https://ncbi.nlm.nih.gov/gene/3364 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the HUS1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | 0.0152402 |
| ADIRF | adipogenesis regulatory factor | 0.0149086 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.0136851 |
| DEFB1 | defensin, beta 1 | 0.0113543 |
| SPON1 | spondin 1, extracellular matrix protein | 0.0112638 |
| TXNDC9 | thioredoxin domain containing 9 | 0.0112589 |
| KLK6 | kallikrein-related peptidase 6 | 0.0107598 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0105231 |
| CRIP2 | cysteine-rich protein 2 | 0.0103874 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0103833 |
| TMEM100 | transmembrane protein 100 | 0.0100752 |
| GPX3 | glutathione peroxidase 3 | 0.00995148 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0097847 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00974997 |
| CLU | clusterin | 0.00974231 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00967255 |
| MT1M | metallothionein 1M | 0.00958479 |
| NNMT | nicotinamide N-methyltransferase | 0.00931329 |
| CLIC5 | chloride intracellular channel 5 | 0.00929968 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 0.0092292 |
| KRT18 | keratin 18, type I | 0.00917237 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00914635 |
| TRIB3 | tribbles pseudokinase 3 | 0.00912468 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00907273 |
| RAI2 | retinoic acid induced 2 | 0.00903921 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00872477 |
| TSPAN12 | tetraspanin 12 | 0.00872039 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.00872008 |
| MSLN | mesothelin | 0.00846517 |
| KLK10 | kallikrein-related peptidase 10 | 0.00820491 |
| EPCAM | epithelial cell adhesion molecule | 0.00806522 |
| IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | 0.0079968 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00790981 |
| HSPA2 | heat shock 70kDa protein 2 | 0.0077266 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00762586 |
| IRS2 | insulin receptor substrate 2 | 0.00758998 |
| TNS3 | tensin 3 | 0.00755044 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 0.00751252 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00748425 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00747984 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | 0.00742002 |
| WT1 | Wilms tumor 1 | 0.00739234 |
| ATP6AP1 | ATPase, H+ transporting, lysosomal accessory protein 1 | 0.00726787 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00726786 |
| COPS7A | COP9 signalosome subunit 7A | 0.00712815 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00706623 |
| TCF4 | transcription factor 4 | 0.00705514 |
| SORBS3 | sorbin and SH3 domain containing 3 | 0.00704061 |
| IL1R1 | interleukin 1 receptor, type I | 0.00698296 |
| MANSC1 | MANSC domain containing 1 | 0.0069576 |
| KLK8 | kallikrein-related peptidase 8 | 0.00690919 |
| PPL | periplakin | 0.00686062 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00680688 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00676283 |
| BCHE | butyrylcholinesterase | 0.00675318 |
| MYO5C | myosin VC | 0.0067452 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00674373 |
| MAGED1 | melanoma antigen family D1 | 0.00673373 |
| FABP1 | fatty acid binding protein 1, liver | 0.00665765 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00661873 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.00660639 |
| SOSTDC1 | sclerostin domain containing 1 | 0.00658605 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | 0.00656109 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.00651261 |
| GTF3A | general transcription factor IIIA | 0.00649396 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.00645946 |
| KRT7 | keratin 7, type II | 0.00642311 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00639398 |
| KIAA0100 | KIAA0100 | 0.00632059 |
| SPEN | spen family transcriptional repressor | 0.00628088 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00627813 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00627351 |
| MICU2 | mitochondrial calcium uptake 2 | 0.00626904 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00626606 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.00618625 |
| SCEL | sciellin | 0.0061617 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 0.00614683 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0061468 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00609443 |
| SLBP | stem-loop binding protein | 0.0060856 |
| DSTN | destrin (actin depolymerizing factor) | 0.00602665 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00602316 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00601955 |
| SOX17 | SRY (sex determining region Y)-box 17 | 0.00600832 |
| GPM6B | glycoprotein M6B | 0.00598695 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00596882 |
| LAMA5 | laminin, alpha 5 | 0.0059548 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.0059291 |
| GAS6 | growth arrest-specific 6 | 0.00591353 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00591107 |
| TSPAN7 | tetraspanin 7 | 0.00590792 |
| C2CD5 | C2 calcium-dependent domain containing 5 | 0.00590306 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00589828 |
| BMP2 | bone morphogenetic protein 2 | 0.00584166 |
| ODC1 | ornithine decarboxylase 1 | 0.00581117 |
| RAD51AP1 | RAD51 associated protein 1 | 0.00580043 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00578352 |
| MUC16 | mucin 16, cell surface associated | 0.00576984 |
| ESR1 | estrogen receptor 1 | 0.00575191 |
| KLK7 | kallikrein-related peptidase 7 | 0.00575108 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.00574642 |
| PCGF2 | polycomb group ring finger 2 | 0.00572191 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0057171 |
| MLF2 | myeloid leukemia factor 2 | 0.00570785 |
| PLXNB1 | plexin B1 | 0.00570448 |
| ELANE | elastase, neutrophil expressed | 0.00566522 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.00566436 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00560945 |
| SLC35F2 | solute carrier family 35, member F2 | 0.00559725 |
| EMX2 | empty spiracles homeobox 2 | 0.00559591 |
| KIAA0232 | KIAA0232 | 0.00558614 |
| MYO1D | myosin ID | 0.00556966 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00553917 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.00553663 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00553266 |
| CLEC3B | C-type lectin domain family 3, member B | 0.00552602 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00551824 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00551357 |
| PLK1 | polo-like kinase 1 | 0.00550991 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00550038 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.00549528 |
| HOXD3 | homeobox D3 | 0.00548241 |
| CLDN3 | claudin 3 | 0.0054803 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00547501 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | 0.00546247 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00544591 |
| POP7 | processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) | 0.00541882 |
| AIFM1 | apoptosis-inducing factor, mitochondrion-associated, 1 | 0.0053755 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 | 0.00532709 |
| CANT1 | calcium activated nucleotidase 1 | 0.00532591 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.00532174 |
| NUDT15 | nudix (nucleoside diphosphate linked moiety X)-type motif 15 | 0.00531049 |
| KRT8 | keratin 8, type II | 0.00529075 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.0052779 |
| PRKCZ | protein kinase C, zeta | 0.00527263 |
| SMAD7 | SMAD family member 7 | 0.00526014 |
| STARD7 | StAR-related lipid transfer (START) domain containing 7 | 0.00525841 |
| CYC1 | cytochrome c-1 | 0.00525331 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00524936 |
| TRIM28 | tripartite motif containing 28 | 0.00524301 |
| GRAMD1C | GRAM domain containing 1C | 0.0052402 |
| TBC1D16 | TBC1 domain family, member 16 | 0.00523732 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00523363 |
| FZD5 | frizzled class receptor 5 | 0.00520783 |
| NXN | nucleoredoxin | 0.00520034 |
| FBXO21 | F-box protein 21 | 0.0052003 |
| LEPR | leptin receptor | 0.00518993 |
| RAB13 | RAB13, member RAS oncogene family | 0.0051692 |
| NCOA6 | nuclear receptor coactivator 6 | 0.00514634 |
| C1R | complement component 1, r subcomponent | 0.00514587 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00513508 |
| DCK | deoxycytidine kinase | 0.00512174 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.0051185 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | 0.00511025 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | 0.0051046 |
| GAB2 | GRB2-associated binding protein 2 | 0.00507898 |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 | 0.00506431 |
| MEPCE | methylphosphate capping enzyme | 0.00505393 |
| UVRAG | UV radiation resistance associated | 0.00504391 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.00503514 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.00503488 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00503038 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00502068 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.00500422 |
| SRI | sorcin | 0.0050013 |
| VBP1 | von Hippel-Lindau binding protein 1 | 0.00499702 |
| MAEA | macrophage erythroblast attacher | 0.00499599 |
| MDH2 | malate dehydrogenase 2, NAD (mitochondrial) | 0.00498705 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00496804 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.00496804 |
| MKKS | McKusick-Kaufman syndrome | 0.00495965 |
| EIF6 | eukaryotic translation initiation factor 6 | 0.00495786 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.0049557 |
| FBXO5 | F-box protein 5 | 0.00494814 |
| APMAP | adipocyte plasma membrane associated protein | 0.00493824 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.00493252 |
| MT1G | metallothionein 1G | 0.00492989 |
| FAM107A | family with sequence similarity 107, member A | 0.00492343 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 0.00491529 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00490151 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 0.00490114 |
| KIF16B | kinesin family member 16B | 0.00489948 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00487418 |
| BCAP31 | B-cell receptor-associated protein 31 | 0.00485474 |
| ITM2C | integral membrane protein 2C | 0.00484915 |
| KIAA0040 | KIAA0040 | 0.00484608 |
| PRTN3 | proteinase 3 | 0.00483973 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.00483779 |
| FMR1 | fragile X mental retardation 1 | 0.0048193 |
| GPAA1 | glycosylphosphatidylinositol anchor attachment 1 | 0.00480069 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.00477086 |
| TNS1 | tensin 1 | 0.00477015 |
| BID | BH3 interacting domain death agonist | 0.00476498 |
| UBAP2L | ubiquitin associated protein 2-like | 0.00476162 |
| PANK2 | pantothenate kinase 2 | 0.00476131 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00474882 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00474443 |
| ANXA3 | annexin A3 | 0.00473003 |
| POLR2H | polymerase (RNA) II (DNA directed) polypeptide H | 0.00472536 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | 0.00471764 |
| MLF1 | myeloid leukemia factor 1 | 0.00470532 |
| EMP2 | epithelial membrane protein 2 | 0.00470297 |
| ACTN4 | actinin, alpha 4 | 0.00469939 |
| MAVS | mitochondrial antiviral signaling protein | 0.00469573 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F | 0.00466934 |
| ENOPH1 | enolase-phosphatase 1 | 0.00466243 |
| PIP4K2C | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma | 0.00465196 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00464253 |
| ARG2 | arginase 2 | 0.00463402 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.00462615 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00461378 |
| C1S | complement component 1, s subcomponent | 0.00460412 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.0045977 |
| YY1AP1 | YY1 associated protein 1 | 0.00459441 |
| AMOTL2 | angiomotin like 2 | 0.00456753 |
| LAMA3 | laminin, alpha 3 | 0.00456534 |
| CCNB1 | cyclin B1 | 0.00455787 |
| MMRN1 | multimerin 1 | 0.00455765 |
| PLTP | phospholipid transfer protein | 0.00454535 |
| MT1F | metallothionein 1F | 0.00453672 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00453279 |
| CLDN1 | claudin 1 | 0.00453186 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.00453178 |
| TPD52 | tumor protein D52 | 0.00452798 |
| JUP | junction plakoglobin | 0.00450843 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.00450628 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00448733 |
| NCALD | neurocalcin delta | 0.00448403 |
| PNOC | prepronociceptin | 0.0044753 |
| CLDN5 | claudin 5 | 0.00443503 |
| NXT1 | nuclear transport factor 2-like export factor 1 | 0.0044206 |
| E2F8 | E2F transcription factor 8 | 0.00442039 |
| SEPHS2 | selenophosphate synthetase 2 | 0.00441224 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00440486 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00440481 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.00440211 |
| KRT20 | keratin 20, type I | 0.00440095 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.00439705 |
| ZNF217 | zinc finger protein 217 | 0.00439568 |
| TASP1 | taspase, threonine aspartase, 1 | 0.00437614 |
| CUL3 | cullin 3 | 0.00436676 |
| CFH | complement factor H | 0.00436564 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 0.00435868 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | 0.00435546 |
| ADI1 | acireductone dioxygenase 1 | 0.00435467 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.00434327 |
| SST | somatostatin | 0.00433988 |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial | 0.00433579 |
| FOXG1 | forkhead box G1 | 0.00433171 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 | 0.00432703 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0120986 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.0118308 |
| LTF | lactotransferrin | -0.0112582 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.0107944 |
| NRIP3 | nuclear receptor interacting protein 3 | -0.0104602 |
| POSTN | periostin, osteoblast specific factor | -0.00999965 |
| IL2RG | interleukin 2 receptor, gamma | -0.009584 |
| CD52 | CD52 molecule | -0.00945849 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00934579 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00932527 |
| IFRD2 | interferon-related developmental regulator 2 | -0.00916431 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00911956 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00908549 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00903798 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00897903 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00875271 |
| S100A8 | S100 calcium binding protein A8 | -0.00870443 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00867696 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00846186 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00844714 |
| AK4 | adenylate kinase 4 | -0.00834858 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.00829521 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00827517 |
| KYNU | kynureninase | -0.00825008 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00822334 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0080704 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | -0.00803562 |
| GLUL | glutamate-ammonia ligase | -0.00788762 |
| VNN1 | vanin 1 | -0.00783564 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00778009 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00777822 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00769509 |
| CD8A | CD8a molecule | -0.00764735 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00762059 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00758337 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00751884 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00751227 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00750988 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | -0.00745959 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.00745671 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00745362 |
| HNMT | histamine N-methyltransferase | -0.00741192 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | -0.00738367 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00736901 |
| IL7R | interleukin 7 receptor | -0.00729781 |
| FCGBP | Fc fragment of IgG binding protein | -0.00729096 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00726162 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00724318 |
| NPR3 | natriuretic peptide receptor 3 | -0.00724001 |
| IFI44 | interferon-induced protein 44 | -0.00721444 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00720151 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00715325 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00712832 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00711705 |
| S100A10 | S100 calcium binding protein A10 | -0.00710796 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00710283 |
| GTPBP8 | GTP-binding protein 8 (putative) | -0.00706638 |
| ADM | adrenomedullin | -0.00702564 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.0070236 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.00697055 |
| DAPK1 | death-associated protein kinase 1 | -0.0069595 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -0.00687941 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00686113 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00682411 |
| SIRT3 | sirtuin 3 | -0.00680168 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00679747 |
| GNLY | granulysin | -0.00679514 |
| PRF1 | perforin 1 (pore forming protein) | -0.00673687 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00666466 |
| IFI44L | interferon-induced protein 44-like | -0.00662143 |
| FGL2 | fibrinogen-like 2 | -0.00659771 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00654852 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00653644 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -0.0065284 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0065172 |
| COCH | cochlin | -0.00651622 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.00651516 |
| REEP1 | receptor accessory protein 1 | -0.00651323 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00649576 |
| KLF2 | Kruppel-like factor 2 | -0.00646244 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00641247 |
| ITK | IL2-inducible T-cell kinase | -0.00640347 |
| ITM2A | integral membrane protein 2A | -0.00635074 |
| S100A7 | S100 calcium binding protein A7 | -0.00633821 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | -0.00633065 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00629424 |
| EGR2 | early growth response 2 | -0.00628239 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00626934 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | -0.00624217 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00620154 |
| RAB14 | RAB14, member RAS oncogene family | -0.00618012 |
| TPBG | trophoblast glycoprotein | -0.00617568 |
| GPC3 | glypican 3 | -0.0061717 |
| AIM2 | absent in melanoma 2 | -0.0061713 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00616122 |
| CD48 | CD48 molecule | -0.00614886 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.00613335 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0061163 |
| FZD2 | frizzled class receptor 2 | -0.00608132 |
| TESC | tescalcin | -0.00607652 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | -0.00601333 |
| LTA4H | leukotriene A4 hydrolase | -0.00600851 |
| CTSH | cathepsin H | -0.00597323 |
| FYB1 | FYN binding protein 1 | -0.00597232 |
| MME | membrane metallo-endopeptidase | -0.00595709 |
| RPL36 | ribosomal protein L36 | -0.00595692 |
| DIPK1A | divergent protein kinase domain 1A | -0.00593605 |
| HDGFL3 | HDGF like 3 | -0.00593507 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00592837 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00591506 |
| HLA-F | major histocompatibility complex, class I, F | -0.00591238 |
| CYBB | cytochrome b-245, beta polypeptide | -0.0059048 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | -0.00589593 |
| TXNIP | thioredoxin interacting protein | -0.00589002 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00587888 |
| XPO7 | exportin 7 | -0.00586138 |
| NELL2 | NEL-like 2 (chicken) | -0.00584217 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | -0.00583673 |
| FST | follistatin | -0.00579831 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00579203 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | -0.00579047 |
| AIF1 | allograft inflammatory factor 1 | -0.00577599 |
| SNAI2 | snail family zinc finger 2 | -0.00577477 |
| NKX3-1 | NK3 homeobox 1 | -0.00576845 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.00575751 |
| CA12 | carbonic anhydrase XII | -0.00574521 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00574083 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00573875 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0057386 |
| ANGPT1 | angiopoietin 1 | -0.00573064 |
| CLDND1 | claudin domain containing 1 | -0.0057294 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.00571802 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00568221 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | -0.00566637 |
| MSRB2 | methionine sulfoxide reductase B2 | -0.00564657 |
| ZNF91 | zinc finger protein 91 | -0.00564061 |
| BBX | bobby sox homolog (Drosophila) | -0.00563592 |
| SELL | selectin L | -0.00560179 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00557499 |
| MMP12 | matrix metallopeptidase 12 | -0.0055523 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | -0.00554865 |
| MDFIC | MyoD family inhibitor domain containing | -0.00553341 |
| RGS10 | regulator of G-protein signaling 10 | -0.00552401 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00551945 |
| SLAMF7 | SLAM family member 7 | -0.00548997 |
| PRKCB | protein kinase C, beta | -0.00548604 |
| TBC1D31 | TBC1 domain family, member 31 | -0.00547517 |
| RCAN1 | regulator of calcineurin 1 | -0.00541147 |
| DUSP6 | dual specificity phosphatase 6 | -0.00540147 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00539 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00538963 |
| CD84 | CD84 molecule | -0.00538763 |
| PXDN | peroxidasin | -0.00536126 |
| PLBD1 | phospholipase B domain containing 1 | -0.00536002 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00534175 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) | -0.00534061 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00532952 |
| IPO7 | importin 7 | -0.00532499 |
| FOXN3 | forkhead box N3 | -0.00530568 |
| RIN2 | Ras and Rab interactor 2 | -0.0053026 |
| CD2 | CD2 molecule | -0.00529619 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | -0.00529033 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00526443 |
| HLA-DOB | major histocompatibility complex, class II, DO beta | -0.00526083 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.00526055 |
| AFP | alpha-fetoprotein | -0.00522516 |
| DUOX2 | dual oxidase 2 | -0.00522347 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00519823 |
| RRAGD | Ras-related GTP binding D | -0.00519598 |
| SV2C | synaptic vesicle glycoprotein 2C | -0.00518721 |
| TYMP | thymidine phosphorylase | -0.00518584 |
| MYBPC1 | myosin binding protein C, slow type | -0.00515767 |
| FN1 | fibronectin 1 | -0.00515192 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | -0.00513969 |
| CERT1 | ceramide transporter 1 | -0.0051364 |
| APOD | apolipoprotein D | -0.00513086 |
| GPR88 | G protein-coupled receptor 88 | -0.00510506 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -0.00510447 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.00508612 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | -0.00507985 |
| IL2RB | interleukin 2 receptor, beta | -0.00506804 |
| ZBTB43 | zinc finger and BTB domain containing 43 | -0.00506436 |
| HOPX | HOP homeobox | -0.00505689 |
| SLAMF8 | SLAM family member 8 | -0.00503861 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.00501572 |
| PRODH | proline dehydrogenase (oxidase) 1 | -0.00500987 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -0.00500026 |
| PLXDC1 | plexin domain containing 1 | -0.00499924 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00499063 |
| TLR2 | toll-like receptor 2 | -0.00498913 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I | -0.00498736 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00498718 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00498695 |
| PCP4 | Purkinje cell protein 4 | -0.00497448 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | -0.00496726 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00495954 |
| HCP5 | HLA complex P5 (non-protein coding) | -0.00495473 |
| RGS4 | regulator of G-protein signaling 4 | -0.00494497 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00494484 |
| KRT5 | keratin 5, type II | -0.00493302 |
| NNAT | neuronatin | -0.00491245 |
| WIPF1 | WAS/WASL interacting protein family, member 1 | -0.00490496 |
| PIPOX | pipecolic acid oxidase | -0.004886 |
| IL32 | interleukin 32 | -0.00487455 |
| HAS2 | hyaluronan synthase 2 | -0.00485013 |
| SPDEF | SAM pointed domain containing ETS transcription factor | -0.00483914 |
| PEG3 | paternally expressed 3 | -0.00483512 |
| XAF1 | XIAP associated factor 1 | -0.00482709 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0048137 |
| LY96 | lymphocyte antigen 96 | -0.0048046 |
| PRKCQ | protein kinase C, theta | -0.00480163 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 | -0.00479578 |
| RAI14 | retinoic acid induced 14 | -0.00479207 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00477778 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00475774 |
| POU2AF1 | POU class 2 associating factor 1 | -0.00475602 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00475506 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00475173 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00475147 |
| CD99 | CD99 molecule | -0.00474673 |
| SP140L | SP140 nuclear body protein-like | -0.00474402 |
| DPP4 | dipeptidyl-peptidase 4 | -0.00473707 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | -0.00473299 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00472818 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00471093 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00469428 |
| UBB | ubiquitin B | -0.00468931 |
| DENND1B | DENN/MADD domain containing 1B | -0.00467954 |
| BIN2 | bridging integrator 2 | -0.0046748 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00467091 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.00467014 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.00466474 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.00464479 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00463426 |
| RDX | radixin | -0.00461851 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 | -0.00461724 |
| IGSF6 | immunoglobulin superfamily, member 6 | -0.00460517 |
| TFF1 | trefoil factor 1 | -0.00460321 |
| MED13 | mediator complex subunit 13 | -0.00459169 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00458082 |
| HLA-B | major histocompatibility complex, class I, B | -0.00457602 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | -0.00457382 |
| PRDX2 | peroxiredoxin 2 | -0.00457149 |
| CD247 | CD247 molecule | -0.0045714 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00456172 |
| SPATA20 | spermatogenesis associated 20 | -0.00455964 |
| LYZ | lysozyme | -0.00455109 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.00454255 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00454245 |
