Hand, Foot And Mouth Disease Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A viral infectious disease that results_in infection located_in skin, has_material_basis_in Human coxsackievirus A16 or has_material_basis_in Human enterovirus 71, which are transmitted_by contaminated fomites, and transmitted_by contact with nose and throat secretions, saliva, blister fluid and stool of infected persons. The infection has_symptom fever, has_symptom poor appetite, has_symptom malaise, has_symptom sore throat, has_symptom painful sores in the mouth, and has_symptom skin rash on the palms of the hands and soles of the feet. (Human Disease Ontology, DOID_10881)
External Link https://www.disgenet.org/browser/0/1/0/C0018572
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Genes

60 genes associated with the disease Hand, Foot And Mouth Disease in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACTB actin, beta
ADRB1 adrenoceptor beta 1
AQP4 aquaporin 4
ATG4B autophagy related 4B, cysteine peptidase
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
CA10 carbonic anhydrase X
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCL4 chemokine (C-C motif) ligand 4
CCL4L1 chemokine (C-C motif) ligand 4-like 1
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CERS1 ceramide synthase 1
CRP C-reactive protein, pentraxin-related
CXCL8 chemokine (C-X-C motif) ligand 8
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DLL1 delta-like 1 (Drosophila)
DLL4 delta-like 4 (Drosophila)
FN1 fibronectin 1
GDE1 glycerophosphodiester phosphodiesterase 1
GDF1 growth differentiation factor 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HMGB1 high mobility group box 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNG interferon, gamma
IL10 interleukin 10
IL13 interleukin 13
IL17A interleukin 17A
IL17F interleukin 17F
IL18 interleukin 18
IL22 interleukin 22
IL37 interleukin 37
IL4 interleukin 4
IL6 interleukin 6
INSRR insulin receptor-related receptor
LOC105371045 uncharacterized LOC105371045
MMP8 matrix metallopeptidase 8
NOTCH1 notch 1
NOTCH2 notch 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PLXNA2 plexin A2
POTEF POTE ankyrin domain family, member F
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
REN renin
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
S100B S100 calcium binding protein B
SCARA3 scavenger receptor class A, member 3
SCARB2 scavenger receptor class B, member 2
SELPLG selectin P ligand
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
TGFB1 transforming growth factor, beta 1
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TNF tumor necrosis factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIP vasoactive intestinal peptide