| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Harringtonine perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Harringtonine_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.0740141 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0706719 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0609591 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0319354 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0319338 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0308278 |
| PCM1 | pericentriolar material 1 | 0.0307524 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0298597 |
| SET | SET nuclear proto-oncogene | 0.0286787 |
| KIF5B | kinesin family member 5B | 0.0278113 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0277946 |
| RPS3 | ribosomal protein S3 | 0.0270571 |
| BRD2 | bromodomain containing 2 | 0.0265003 |
| RPL36 | ribosomal protein L36 | 0.0264434 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0234539 |
| CCNL1 | cyclin L1 | 0.0231925 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0222963 |
| RPL37A | ribosomal protein L37a | 0.0222663 |
| CPOX | coproporphyrinogen oxidase | 0.0217522 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0216111 |
| RPS12 | ribosomal protein S12 | 0.020986 |
| PCNP | PEST proteolytic signal containing nuclear protein | 0.0203904 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0202271 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0201901 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0197139 |
| RPS2 | ribosomal protein S2 | 0.0193878 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0189833 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0187872 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0186168 |
| CEP95 | centrosomal protein 95kDa | 0.0175992 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0175444 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0170131 |
| MSH6 | mutS homolog 6 | 0.0167141 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0157828 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0152332 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0150073 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0147312 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0142942 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0141872 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0141436 |
| BRD8 | bromodomain containing 8 | 0.0141351 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0138566 |
| RBM25 | RNA binding motif protein 25 | 0.0138562 |
| RPL18 | ribosomal protein L18 | 0.0138423 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0137622 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0136936 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0136622 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0136003 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.013415 |
| ATP11A | ATPase, class VI, type 11A | 0.0132848 |
| TNPO1 | transportin 1 | 0.012962 |
| E2F7 | E2F transcription factor 7 | 0.0128177 |
| RPS19 | ribosomal protein S19 | 0.0127887 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 | 0.0127619 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0126801 |
| QKI | QKI, KH domain containing, RNA binding | 0.0126576 |
| MTIF2 | mitochondrial translational initiation factor 2 | 0.0124622 |
| RPL5 | ribosomal protein L5 | 0.0124442 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0121905 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0121347 |
| DENND4A | DENN/MADD domain containing 4A | 0.0120856 |
| CASC3 | cancer susceptibility candidate 3 | 0.0120099 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0119962 |
| SMAD5 | SMAD family member 5 | 0.0119136 |
| RPL26 | ribosomal protein L26 | 0.011894 |
| PTMA | prothymosin, alpha | 0.0118524 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.011824 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0118215 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0117749 |
| CCAR1 | cell division cycle and apoptosis regulator 1 | 0.0116255 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0115927 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0115277 |
| CD83 | CD83 molecule | 0.0114964 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0114073 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0114014 |
| RPS7 | ribosomal protein S7 | 0.0113969 |
| LIMA1 | LIM domain and actin binding 1 | 0.0111667 |
| CDK19 | cyclin-dependent kinase 19 | 0.0111615 |
| ITSN2 | intersectin 2 | 0.0110961 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0110397 |
| LEO1 | Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.0110319 |
| SSR1 | signal sequence receptor, alpha | 0.0109228 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.010861 |
| SF3B6 | splicing factor 3b, subunit 6, 14kDa | 0.0108253 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0108004 |
| RPS17 | ribosomal protein S17 | 0.0107916 |
| INSIG2 | insulin induced gene 2 | 0.0106461 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0105981 |
| RHBDD1 | rhomboid domain containing 1 | 0.01055 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0105493 |
| KIF3A | kinesin family member 3A | 0.0105387 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.010425 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0102492 |
| WDR45B | WD repeat domain 45B | 0.0101862 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.010102 |
| THOC1 | THO complex 1 | 0.0100235 |
| SEPTIN7 | septin 7 | 0.0100118 |
| PLEC | plectin | 0.00994229 |
| TMEM39A | transmembrane protein 39A | 0.00993858 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.00989343 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.228048 |
| NLGN1 | neuroligin 1 | -0.214412 |
| VIM | vimentin | -0.200451 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.151333 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.117054 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.105563 |
| PCDH7 | protocadherin 7 | -0.102599 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.102277 |
| RASAL2 | RAS protein activator like 2 | -0.0996603 |
| DST | dystonin | -0.0836515 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0810038 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0743059 |
| KLF6 | Kruppel-like factor 6 | -0.0721559 |
| JMJD1C | jumonji domain containing 1C | -0.0719485 |
| HMGA2 | high mobility group AT-hook 2 | -0.0689684 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0655711 |
| MMP12 | matrix metallopeptidase 12 | -0.0647263 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0643193 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0637834 |
| ACTG1 | actin gamma 1 | -0.0614299 |
| HDAC9 | histone deacetylase 9 | -0.0600769 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0581897 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0533498 |
| EHBP1 | EH domain binding protein 1 | -0.0526095 |
| EGR1 | early growth response 1 | -0.0522669 |
| MGAT4C | MGAT4 family, member C | -0.0506639 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.050518 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0485471 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.048478 |
| NAV3 | neuron navigator 3 | -0.0483833 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0475335 |
| TMEM41B | transmembrane protein 41B | -0.0468607 |
| NHSL1 | NHS-like 1 | -0.0462721 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0441699 |
| YAP1 | Yes-associated protein 1 | -0.0441158 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0433039 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0432765 |
| BCHE | butyrylcholinesterase | -0.0426808 |
| TUBA1B | tubulin, alpha 1b | -0.0420752 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0417679 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0415947 |
| ZNF804A | zinc finger protein 804A | -0.0413453 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0412189 |
| DPYD | dihydropyrimidine dehydrogenase | -0.041076 |
| PDGFC | platelet derived growth factor C | -0.0407649 |
| ADIPOR2 | adiponectin receptor 2 | -0.0380734 |
| CLDN1 | claudin 1 | -0.0375377 |
| EDARADD | EDAR-associated death domain | -0.0373194 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0369477 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0367602 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.036287 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0355726 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0355162 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0349134 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0348019 |
| UBC | ubiquitin C | -0.034717 |
| HMGA1 | high mobility group AT-hook 1 | -0.0345108 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0328577 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0324287 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0317986 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.031698 |
| RTN4 | reticulon 4 | -0.0316573 |
| S100A10 | S100 calcium binding protein A10 | -0.0314754 |
| RPL35A | ribosomal protein L35a | -0.031342 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0312258 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0307912 |
| SETX | senataxin | -0.0305526 |
| MAP1B | microtubule-associated protein 1B | -0.0303426 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0299683 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0299467 |
| CALR | calreticulin | -0.0297544 |
| MYPN | myopalladin | -0.0294968 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0292864 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0289288 |
| VMP1 | vacuole membrane protein 1 | -0.0286056 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0284955 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0284353 |
| JUN | jun proto-oncogene | -0.0282578 |
| TMSB10 | thymosin beta 10 | -0.0280626 |
| CUX1 | cut-like homeobox 1 | -0.0276763 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0274711 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0269738 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0269161 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0265793 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0262469 |
| SLC38A1 | solute carrier family 38, member 1 | -0.026237 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0258984 |
| PLK2 | polo-like kinase 2 | -0.0258569 |
| GCG | glucagon | -0.0257815 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0253985 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0253489 |
| DTNA | dystrobrevin, alpha | -0.0253239 |
| SYT1 | synaptotagmin I | -0.0252247 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0250893 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0248422 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0248166 |
| BNC2 | basonuclin 2 | -0.0247505 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0245233 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0244174 |
| CMIP | c-Maf inducing protein | -0.0242243 |
