| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Harringtonine perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Harringtonine_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.112082 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0575547 |
| KLF10 | Kruppel-like factor 10 | 0.0450874 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0447639 |
| CADM1 | cell adhesion molecule 1 | 0.0421607 |
| EGR1 | early growth response 1 | 0.0391696 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0374271 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0345591 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0320277 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0283527 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.028051 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.028034 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0277198 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0272826 |
| MED13 | mediator complex subunit 13 | 0.0270241 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0266873 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0248197 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0246101 |
| KLF6 | Kruppel-like factor 6 | 0.0241886 |
| MSI2 | musashi RNA-binding protein 2 | 0.0239604 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0231099 |
| MED13L | mediator complex subunit 13-like | 0.0229555 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0228161 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0221766 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0220804 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0220215 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0214132 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0211458 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0207757 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0205858 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0201348 |
| IRF1 | interferon regulatory factor 1 | 0.0199271 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0198915 |
| XPO1 | exportin 1 | 0.0198035 |
| HIP1 | huntingtin interacting protein 1 | 0.0197761 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0190997 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0188767 |
| OGA | O-GlcNAcase | 0.018763 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0184933 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0184658 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0183197 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0181852 |
| ENAH | enabled homolog (Drosophila) | 0.0181236 |
| H1-0 | H1.0 linker histone | 0.018097 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0180512 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0178051 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0177133 |
| LPIN1 | lipin 1 | 0.017517 |
| PLCB4 | phospholipase C, beta 4 | 0.0174982 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0171828 |
| IL6ST | interleukin 6 signal transducer | 0.016922 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0167677 |
| ZFP36 | ZFP36 ring finger protein | 0.0165979 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0165602 |
| ERBIN | erbb2 interacting protein | 0.0165402 |
| RYBP | RING1 and YY1 binding protein | 0.0164677 |
| BRD4 | bromodomain containing 4 | 0.0162707 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0162452 |
| ICAM1 | intercellular adhesion molecule 1 | 0.016186 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0160637 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0159715 |
| TRIM37 | tripartite motif containing 37 | 0.0157267 |
| SERTAD2 | SERTA domain containing 2 | 0.0157204 |
| PER1 | period circadian clock 1 | 0.0156368 |
| H3-3B | H3.3 histone B | 0.0154265 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0152237 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0152195 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0149281 |
| TJP2 | tight junction protein 2 | 0.0149027 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0146744 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0146364 |
| QKI | QKI, KH domain containing, RNA binding | 0.014339 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0142505 |
| KCNT2 | potassium channel, sodium activated subfamily T, member 2 | 0.0142237 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | 0.014209 |
| SMAD3 | SMAD family member 3 | 0.0142079 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0142001 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) | 0.014147 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0141065 |
| SQSTM1 | sequestosome 1 | 0.0138911 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0138747 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0138727 |
| YY1AP1 | YY1 associated protein 1 | 0.0138592 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0137894 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 | 0.0136437 |
| LMNA | lamin A/C | 0.0136021 |
| SETD2 | SET domain containing 2 | 0.0135849 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.013572 |
| TRAF3 | TNF receptor-associated factor 3 | 0.0135051 |
| ITGAV | integrin, alpha V | 0.0134518 |
| ITSN2 | intersectin 2 | 0.0131493 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0131086 |
| TXNIP | thioredoxin interacting protein | 0.0130783 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0130729 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0130098 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0129967 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0129634 |
| PRTG | protogenin | 0.0128177 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0127757 |
| POTEF | POTE ankyrin domain family, member F | 0.0126928 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0579244 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0542809 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0426032 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0348135 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0336512 |
| NRG1 | neuregulin 1 | -0.0309577 |
| FAM13A | family with sequence similarity 13, member A | -0.0279896 |
| NDRG1 | N-myc downstream regulated 1 | -0.0276181 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0271368 |
| MEIS2 | Meis homeobox 2 | -0.0270148 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0269924 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0269897 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0269067 |
| FMN1 | formin 1 | -0.0249078 |
| RNF213 | ring finger protein 213 | -0.0248509 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0223361 |
| PLAT | plasminogen activator, tissue | -0.0220603 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0213443 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0202435 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0192207 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.019161 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0191 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0182456 |
| GPC5 | glypican 5 | -0.0178683 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0178678 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0168462 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0167209 |
| STC1 | stanniocalcin 1 | -0.0163844 |
| COL3A1 | collagen, type III, alpha 1 | -0.0162834 |
| FNBP1 | formin binding protein 1 | -0.0161995 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.015436 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0153329 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0152691 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0152478 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0151851 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0151243 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0150753 |
| PCDH9 | protocadherin 9 | -0.0149278 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0147403 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0144192 |
| LSAMP | limbic system-associated membrane protein | -0.0143745 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0143582 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0141724 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0141588 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.014064 |
| PHF3 | PHD finger protein 3 | -0.0137862 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0135146 |
| MAP1B | microtubule-associated protein 1B | -0.0133618 |
| SMYD3 | SET and MYND domain containing 3 | -0.013328 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0130124 |
| GDF15 | growth differentiation factor 15 | -0.0128456 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0128 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0126549 |
| SYT1 | synaptotagmin I | -0.0121318 |
| WDR45B | WD repeat domain 45B | -0.011846 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0117622 |
| RUNX1 | runt-related transcription factor 1 | -0.0116697 |
| FLNB | filamin B, beta | -0.0116639 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0116175 |
| TOB1 | transducer of ERBB2, 1 | -0.0114858 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0112928 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0112841 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.011252 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0112122 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.011187 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0111425 |
| LDHA | lactate dehydrogenase A | -0.0111006 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0110522 |
| CADM2 | cell adhesion molecule 2 | -0.0110361 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0109811 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0109442 |
| PGK1 | phosphoglycerate kinase 1 | -0.01085 |
| COPA | coatomer protein complex, subunit alpha | -0.0106979 |
| DYM | dymeclin | -0.010553 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0105431 |
| ATRNL1 | attractin-like 1 | -0.0104934 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0104261 |
| ENO1 | enolase 1, (alpha) | -0.0104131 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0103835 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0103708 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0103452 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0103256 |
| CALU | calumenin | -0.0102686 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0101499 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0100206 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.00987758 |
| DPH6 | diphthamine biosynthesis 6 | -0.00987631 |
| KIAA1958 | KIAA1958 | -0.00985277 |
| PTMA | prothymosin, alpha | -0.00960709 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00951579 |
| DIAPH2 | diaphanous-related formin 2 | -0.00943091 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.00931287 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00930285 |
| NREP | neuronal regeneration related protein | -0.00918793 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.00910781 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.00906001 |
| CCDC47 | coiled-coil domain containing 47 | -0.00904876 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.00903668 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.00901482 |
| TRIM25 | tripartite motif containing 25 | -0.0090101 |
