| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Harringtonine perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Harringtonine_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SQSTM1 | sequestosome 1 | 0.156597 |
| EGR1 | early growth response 1 | 0.102687 |
| JUN | jun proto-oncogene | 0.0961291 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0737433 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0684478 |
| KLF10 | Kruppel-like factor 10 | 0.0674839 |
| SETX | senataxin | 0.0520725 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0511182 |
| ZNF292 | zinc finger protein 292 | 0.0431458 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0405095 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0399975 |
| FAT1 | FAT atypical cadherin 1 | 0.0370848 |
| SPAG9 | sperm associated antigen 9 | 0.034783 |
| FNIP2 | folliculin interacting protein 2 | 0.0331088 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.032842 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0324765 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | 0.0316729 |
| FNIP1 | folliculin interacting protein 1 | 0.0316647 |
| H1-0 | H1.0 linker histone | 0.030239 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0282245 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0275486 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0272217 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0255025 |
| PER1 | period circadian clock 1 | 0.0248502 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0247668 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0246721 |
| H3-3B | H3.3 histone B | 0.0241056 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0236761 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0234668 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.023068 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0229948 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0228491 |
| HDAC9 | histone deacetylase 9 | 0.0227918 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0227173 |
| KLF6 | Kruppel-like factor 6 | 0.0219359 |
| TOP1 | topoisomerase (DNA) I | 0.0216997 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0216548 |
| DUSP10 | dual specificity phosphatase 10 | 0.0215876 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0209385 |
| BRD2 | bromodomain containing 2 | 0.0208802 |
| INTS6 | integrator complex subunit 6 | 0.0206793 |
| CRYM | crystallin, mu | 0.0200153 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0199242 |
| LMO7 | LIM domain 7 | 0.0196899 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0184252 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0182121 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0181129 |
| DST | dystonin | 0.0180415 |
| IRS2 | insulin receptor substrate 2 | 0.0175074 |
| RESF1 | retroelement silencing factor 1 | 0.0174335 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0173351 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0167934 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0164463 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0162827 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0161619 |
| SNX9 | sorting nexin 9 | 0.0161009 |
| SMAD3 | SMAD family member 3 | 0.0160945 |
| SLC25A25 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 | 0.0152932 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0152368 |
| SPNS2 | spinster homolog 2 (Drosophila) | 0.0151682 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0150867 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0148565 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0145911 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.014425 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0143882 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0143711 |
| TEX14 | testis expressed 14 | 0.0143494 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0142456 |
| ARRDC4 | arrestin domain containing 4 | 0.0142237 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0140811 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.013762 |
| SON | SON DNA binding protein | 0.013653 |
| ZFP36 | ZFP36 ring finger protein | 0.013619 |
| MAPK6 | mitogen-activated protein kinase 6 | 0.0133726 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0133259 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0132799 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0132021 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0131374 |
| PER3 | period circadian clock 3 | 0.0130848 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | 0.0130812 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0130634 |
| TPP2 | tripeptidyl peptidase II | 0.0130483 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0128919 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0128885 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.012837 |
| IER3 | immediate early response 3 | 0.0126618 |
| FOSL2 | FOS-like antigen 2 | 0.0126078 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.0125574 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0124446 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0124401 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0122995 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0122554 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0121538 |
| RNF103-CHMP3 | RNF103-CHMP3 readthrough | 0.0120912 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 0.012038 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0120196 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0118529 |
| GOLGA4 | golgin A4 | 0.0118339 |
| COMMD10 | COMM domain containing 10 | 0.0116987 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0116782 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.116952 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.1035 |
| LCN2 | lipocalin 2 | -0.0941202 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0939727 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0866981 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0824533 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0649899 |
| HLA-B | major histocompatibility complex, class I, B | -0.0624331 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0538138 |
| PTMA | prothymosin, alpha | -0.0496534 |
| FTL | ferritin, light polypeptide | -0.0470686 |
| NDRG1 | N-myc downstream regulated 1 | -0.0466642 |
| NCKAP5 | NCK-associated protein 5 | -0.0453864 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0448009 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0446611 |
| RPL35A | ribosomal protein L35a | -0.0423958 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0408832 |
| MT2A | metallothionein 2A | -0.0393931 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0389041 |
| TMSB10 | thymosin beta 10 | -0.0378829 |
| RAD51B | RAD51 paralog B | -0.0374691 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0374444 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0358714 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.035871 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0352688 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0344929 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0340769 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0340621 |
| PGK1 | phosphoglycerate kinase 1 | -0.0332988 |
| PHF3 | PHD finger protein 3 | -0.0324944 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0323572 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.032348 |
| RPLP1 | ribosomal protein, large, P1 | -0.0319673 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0310124 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0305149 |
| PKM | pyruvate kinase, muscle | -0.0298699 |
| RPS19 | ribosomal protein S19 | -0.0296528 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.029186 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0288232 |
| ENO1 | enolase 1, (alpha) | -0.0284487 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0283045 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0275485 |
| RPL34 | ribosomal protein L34 | -0.0269769 |
| RNF213 | ring finger protein 213 | -0.0268977 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0267314 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0263375 |
| RPL12 | ribosomal protein L12 | -0.0263365 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0262412 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0261165 |
| FOXP1 | forkhead box P1 | -0.0257537 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0253157 |
| RPL11 | ribosomal protein L11 | -0.0252468 |
| EPCAM | epithelial cell adhesion molecule | -0.0247567 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0245758 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.024548 |
| S100A10 | S100 calcium binding protein A10 | -0.0242973 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0241298 |
| IFNGR1 | interferon gamma receptor 1 | -0.0233676 |
| RPS6 | ribosomal protein S6 | -0.0231625 |
| RRBP1 | ribosome binding protein 1 | -0.0229216 |
| RPL19 | ribosomal protein L19 | -0.0227912 |
| MEIS2 | Meis homeobox 2 | -0.0227881 |
| TRERF1 | transcriptional regulating factor 1 | -0.022763 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0227513 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0224995 |
| MUC13 | mucin 13, cell surface associated | -0.0224735 |
| MUC20 | mucin 20, cell surface associated | -0.0222229 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0221551 |
| RPL23 | ribosomal protein L23 | -0.0221166 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0220862 |
| XAF1 | XIAP associated factor 1 | -0.0219825 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.021925 |
| RPS8 | ribosomal protein S8 | -0.0215319 |
| RNF149 | ring finger protein 149 | -0.0214698 |
| APOL1 | apolipoprotein L, 1 | -0.0214374 |
| RPS24 | ribosomal protein S24 | -0.0213355 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0211162 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0211138 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0206699 |
| DSTN | destrin (actin depolymerizing factor) | -0.0206333 |
| HLA-E | major histocompatibility complex, class I, E | -0.0206155 |
| PRELID2 | PRELI domain containing 2 | -0.0204041 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0203231 |
| CALR | calreticulin | -0.0201962 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0201569 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0200336 |
| MT1X | metallothionein 1X | -0.0200313 |
| PTGR1 | prostaglandin reductase 1 | -0.0199574 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0198709 |
| ANXA4 | annexin A4 | -0.0197654 |
| RPL31 | ribosomal protein L31 | -0.01975 |
| LYZ | lysozyme | -0.0196805 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0196631 |
| SSH2 | slingshot protein phosphatase 2 | -0.0196106 |
| RPL37 | ribosomal protein L37 | -0.0194324 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0194007 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0192849 |
| TMC5 | transmembrane channel-like 5 | -0.0192074 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0190878 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0190498 |
