| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Harringtonine perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Harringtonine_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.0971821 |
| TXNIP | thioredoxin interacting protein | 0.0889278 |
| EGR1 | early growth response 1 | 0.0810634 |
| SQSTM1 | sequestosome 1 | 0.0804204 |
| PLEC | plectin | 0.0790504 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0698031 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0660467 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0600424 |
| MCL1 | myeloid cell leukemia 1 | 0.0595504 |
| HDAC9 | histone deacetylase 9 | 0.0575023 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0515768 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0501674 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0484335 |
| LAMC2 | laminin, gamma 2 | 0.0461161 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.038558 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0374276 |
| EGFR | epidermal growth factor receptor | 0.0361959 |
| TXNRD1 | thioredoxin reductase 1 | 0.0361645 |
| CDK6 | cyclin-dependent kinase 6 | 0.0356509 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0342126 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0335098 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0331736 |
| RIGI | RNA sensor RIG-I | 0.0330625 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0329737 |
| FOSL1 | FOS-like antigen 1 | 0.0327384 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0325356 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.030194 |
| TOP1 | topoisomerase (DNA) I | 0.029366 |
| ZNF217 | zinc finger protein 217 | 0.0288037 |
| RASAL2 | RAS protein activator like 2 | 0.0287272 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.028719 |
| IL6ST | interleukin 6 signal transducer | 0.0276051 |
| DST | dystonin | 0.0275137 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.026891 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0266497 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0265588 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0261169 |
| UBC | ubiquitin C | 0.0260624 |
| SFPQ | splicing factor proline/glutamine-rich | 0.025728 |
| KLF10 | Kruppel-like factor 10 | 0.0252518 |
| HMGA2 | high mobility group AT-hook 2 | 0.0243404 |
| JUN | jun proto-oncogene | 0.0243158 |
| ASPH | aspartate beta-hydroxylase | 0.0236283 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0233755 |
| ARRDC3 | arrestin domain containing 3 | 0.023348 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0226833 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0226324 |
| H1-0 | H1.0 linker histone | 0.0222679 |
| PLAU | plasminogen activator, urokinase | 0.0221655 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0220498 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.020893 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0208791 |
| CPNE8 | copine VIII | 0.0208651 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0197042 |
| ADAR | adenosine deaminase, RNA-specific | 0.0194624 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0194472 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0192136 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0192036 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0191553 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0188692 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | 0.0188025 |
| JAG1 | jagged 1 | 0.0187288 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0184312 |
| DOCK4 | dedicator of cytokinesis 4 | 0.018387 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0183529 |
| IFI44 | interferon-induced protein 44 | 0.0183101 |
| LYST | lysosomal trafficking regulator | 0.0182779 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0181273 |
| SETX | senataxin | 0.0180438 |
| IRF1 | interferon regulatory factor 1 | 0.0180406 |
| KRT17 | keratin 17, type I | 0.0175487 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.017534 |
| SP100 | SP100 nuclear antigen | 0.0173386 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0171106 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0170848 |
| FRMD6 | FERM domain containing 6 | 0.017079 |
| YAP1 | Yes-associated protein 1 | 0.0170473 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0169438 |
| RIN2 | Ras and Rab interactor 2 | 0.0169099 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0167879 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0167538 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.016726 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0165276 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0162134 |
| PER1 | period circadian clock 1 | 0.016211 |
| ITGAV | integrin, alpha V | 0.0161905 |
| IFI44L | interferon-induced protein 44-like | 0.0159475 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0158467 |
| PPL | periplakin | 0.0157816 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0155984 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0154976 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0154296 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0152688 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0152249 |
| ERBIN | erbb2 interacting protein | 0.0150144 |
| SAMD9L | sterile alpha motif domain containing 9-like | 0.0147905 |
| ZFP36 | ZFP36 ring finger protein | 0.0147373 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0145902 |
| PMP22 | peripheral myelin protein 22 | 0.0144618 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.014439 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.19914 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.172162 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.139037 |
| PTMA | prothymosin, alpha | -0.135956 |
| TMSB10 | thymosin beta 10 | -0.125829 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0943914 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0827276 |
| RPS6 | ribosomal protein S6 | -0.0791372 |
| MEF2A | myocyte enhancer factor 2A | -0.0754514 |
| GNAS | GNAS complex locus | -0.0752164 |
| PGK1 | phosphoglycerate kinase 1 | -0.0726231 |
| RPL11 | ribosomal protein L11 | -0.0658638 |
| SULF1 | sulfatase 1 | -0.0640925 |
| MTSS1 | metastasis suppressor 1 | -0.0638591 |
| NDRG1 | N-myc downstream regulated 1 | -0.0623015 |
| IGF2 | insulin-like growth factor 2 | -0.0609886 |
| SQLE | squalene epoxidase | -0.060311 |
| RPS8 | ribosomal protein S8 | -0.0598822 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0583577 |
| MT2A | metallothionein 2A | -0.0571208 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0566371 |
| S100A10 | S100 calcium binding protein A10 | -0.0558686 |
| RPLP1 | ribosomal protein, large, P1 | -0.0558547 |
| CLU | clusterin | -0.0554552 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0540954 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.054021 |
| STC1 | stanniocalcin 1 | -0.0539984 |
| RPS19 | ribosomal protein S19 | -0.0533697 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0510373 |
| RPLP2 | ribosomal protein, large, P2 | -0.0507438 |
| LMO7 | LIM domain 7 | -0.0507386 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0506289 |
| RPS21 | ribosomal protein S21 | -0.0491873 |
| RPS3 | ribosomal protein S3 | -0.0489317 |
| CD44 | CD44 molecule (Indian blood group) | -0.0486399 |
| EMP1 | epithelial membrane protein 1 | -0.0480276 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0469759 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0465099 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0452793 |
| B2M | beta-2-microglobulin | -0.0451691 |
| FLNB | filamin B, beta | -0.0441358 |
| FTL | ferritin, light polypeptide | -0.0440251 |
| ANXA2 | annexin A2 | -0.0438004 |
| RPL12 | ribosomal protein L12 | -0.0437614 |
| WASF2 | WAS protein family, member 2 | -0.0437327 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0415215 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0414711 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0414185 |
| CALU | calumenin | -0.0402411 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0394807 |
| RPL35A | ribosomal protein L35a | -0.0385492 |
| RACK1 | receptor for activated C kinase 1 | -0.0382722 |
| GOLGA4 | golgin A4 | -0.0380954 |
| LDHA | lactate dehydrogenase A | -0.0380952 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0373355 |
| RPL34 | ribosomal protein L34 | -0.0370512 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0367364 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.036422 |
| RPL37 | ribosomal protein L37 | -0.0357855 |
| MORF4L2 | mortality factor 4 like 2 | -0.035426 |
| RPLP0 | ribosomal protein, large, P0 | -0.0352463 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0347236 |
| RPS12 | ribosomal protein S12 | -0.0346364 |
| RPS25 | ribosomal protein S25 | -0.0343368 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0342682 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0340346 |
| RPS13 | ribosomal protein S13 | -0.0339041 |
| S100A11 | S100 calcium binding protein A11 | -0.033771 |
| LOC112694756 | uncharaterized LOC112694756 | -0.033561 |
| RPL31 | ribosomal protein L31 | -0.0328804 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0328224 |
| RPL37A | ribosomal protein L37a | -0.032818 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0327369 |
| S100A9 | S100 calcium binding protein A9 | -0.0326756 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0325229 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0324606 |
| RPL8 | ribosomal protein L8 | -0.0321701 |
| YBX1 | Y box binding protein 1 | -0.0315936 |
| RPL5 | ribosomal protein L5 | -0.03158 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0315547 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0315289 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0312723 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0309106 |
| ANLN | anillin, actin binding protein | -0.0307025 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.030675 |
| RPL19 | ribosomal protein L19 | -0.0306627 |
| RPS27 | ribosomal protein S27 | -0.0305636 |
| RPL27A | ribosomal protein L27a | -0.0304035 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.030296 |
| RPL36 | ribosomal protein L36 | -0.030145 |
| YBX3 | Y box binding protein 3 | -0.0300083 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0298936 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0295209 |
| CANX | calnexin | -0.029077 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0289007 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.028777 |
| RPL26 | ribosomal protein L26 | -0.028627 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0284776 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0284741 |
| GUK1 | guanylate kinase 1 | -0.0283273 |
