| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Harringtonine perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Harringtonine_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | 0.111249 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.10244 |
| EGR1 | early growth response 1 | 0.100436 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.078397 |
| JUN | jun proto-oncogene | 0.0730832 |
| VCL | vinculin | 0.0584655 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0582144 |
| TMSB10 | thymosin beta 10 | 0.0561776 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0508293 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0502029 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0474734 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.0449939 |
| BRD2 | bromodomain containing 2 | 0.0441236 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.042922 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0405232 |
| RNF217 | ring finger protein 217 | 0.0385104 |
| TXNIP | thioredoxin interacting protein | 0.0373537 |
| FLNB | filamin B, beta | 0.0368106 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0366153 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0361351 |
| MYO1E | myosin IE | 0.0354593 |
| KLF10 | Kruppel-like factor 10 | 0.0340655 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0324966 |
| ASPH | aspartate beta-hydroxylase | 0.0312966 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0311905 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0309518 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0308895 |
| ZFP36 | ZFP36 ring finger protein | 0.030836 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0307793 |
| EGFR | epidermal growth factor receptor | 0.0302268 |
| LAMA4 | laminin, alpha 4 | 0.029908 |
| IER2 | immediate early response 2 | 0.0294344 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0293243 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0290786 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.029031 |
| SQSTM1 | sequestosome 1 | 0.0289844 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0280047 |
| RAD51B | RAD51 paralog B | 0.0280012 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0275446 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0265783 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0259678 |
| ACTG1 | actin gamma 1 | 0.0256598 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0254971 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0253815 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.0252909 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0251858 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0250025 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0249855 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0249434 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0244078 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0237054 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0231149 |
| SVIL | supervillin | 0.022995 |
| ARRDC4 | arrestin domain containing 4 | 0.0226984 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0224825 |
| ECT2 | epithelial cell transforming 2 | 0.0224166 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0220893 |
| ONECUT3 | one cut homeobox 3 | 0.0220212 |
| FHIT | fragile histidine triad | 0.0220124 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0219768 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0216485 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0214412 |
| CLOCK | clock circadian regulator | 0.0213182 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0207437 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0205178 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0205101 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0204865 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0203089 |
| POTEF | POTE ankyrin domain family, member F | 0.0202876 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0201079 |
| MT2A | metallothionein 2A | 0.0200107 |
| RCOR1 | REST corepressor 1 | 0.0200044 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0198263 |
| PCDH9 | protocadherin 9 | 0.0197296 |
| LSAMP | limbic system-associated membrane protein | 0.0196183 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0195999 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0193788 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0191258 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0187331 |
| MCL1 | myeloid cell leukemia 1 | 0.0184706 |
| SIK3 | SIK family kinase 3 | 0.0178751 |
| CNKSR3 | CNKSR family member 3 | 0.0176443 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0175188 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0172331 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0172126 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0171554 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.0170114 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.016787 |
| INTS6 | integrator complex subunit 6 | 0.0167542 |
| IER3 | immediate early response 3 | 0.016695 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0163911 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0163272 |
| RPL37A | ribosomal protein L37a | 0.0161856 |
| MYOF | myoferlin | 0.0159917 |
| NRXN3 | neurexin 3 | 0.0159737 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0159523 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0157985 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0151862 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0151171 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0151059 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.212483 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.211114 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.166478 |
| GOLGA4 | golgin A4 | -0.096808 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0829292 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0778256 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0763558 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.068578 |
| EREG | epiregulin | -0.0680165 |
| LDHA | lactate dehydrogenase A | -0.0660173 |
| GDF15 | growth differentiation factor 15 | -0.0656018 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0604862 |
| FAM13A | family with sequence similarity 13, member A | -0.0603076 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.056825 |
| NDRG1 | N-myc downstream regulated 1 | -0.056273 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.05609 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0560666 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0540497 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0516044 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0500012 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0484303 |
| RNF43 | ring finger protein 43 | -0.0483387 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0458214 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0454025 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0447701 |
| COG5 | component of oligomeric golgi complex 5 | -0.0434153 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0425646 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.040328 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0400066 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0391935 |
| ZNF292 | zinc finger protein 292 | -0.0389116 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0385898 |
| RNF145 | ring finger protein 145 | -0.0385693 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0385343 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0376088 |
| NEBL | nebulette | -0.0373796 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0369291 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0361913 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0358626 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0344092 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0344031 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0341589 |
| KITLG | KIT ligand | -0.0333351 |
| CANX | calnexin | -0.0329886 |
| TRIM2 | tripartite motif containing 2 | -0.0324428 |
| PCDHB16 | protocadherin beta 16 | -0.0322139 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0321501 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0316132 |
| TPD52 | tumor protein D52 | -0.0314742 |
| DSPP | dentin sialophosphoprotein | -0.0308163 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0307196 |
| TXNRD1 | thioredoxin reductase 1 | -0.0302853 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.0296009 |
| SEC24D | SEC24 family member D | -0.029001 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0289292 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0288108 |
| RPLP0 | ribosomal protein, large, P0 | -0.0285555 |
| PRSS3 | protease, serine, 3 | -0.0283001 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0281715 |
| PTEN | phosphatase and tensin homolog | -0.0280891 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0279436 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0278687 |
| WDR45B | WD repeat domain 45B | -0.0278492 |
| RBM39 | RNA binding motif protein 39 | -0.0277894 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0277713 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0277217 |
| HDLBP | high density lipoprotein binding protein | -0.0277049 |
| ANXA2 | annexin A2 | -0.0274029 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.027334 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0273304 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0272927 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0267169 |
| ZNF654 | zinc finger protein 654 | -0.0263075 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0262924 |
| LMAN1 | lectin, mannose-binding, 1 | -0.026184 |
| RPL35A | ribosomal protein L35a | -0.0258652 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0257471 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0257317 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0256022 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0255487 |
| USP3 | ubiquitin specific peptidase 3 | -0.0255307 |
| CD44 | CD44 molecule (Indian blood group) | -0.0255096 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.0255034 |
| INSIG1 | insulin induced gene 1 | -0.0254308 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0253952 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0251998 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0250335 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0248705 |
| COPA | coatomer protein complex, subunit alpha | -0.0247901 |
| RPS24 | ribosomal protein S24 | -0.0247032 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0246678 |
| RPL34 | ribosomal protein L34 | -0.0246367 |
| TNS4 | tensin 4 | -0.0241282 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0240287 |
| RLF | rearranged L-myc fusion | -0.0240251 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0238443 |
| RRBP1 | ribosome binding protein 1 | -0.0237814 |
| GPHN | gephyrin | -0.0236163 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0233775 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0232642 |
