| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Harringtonine perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Harringtonine_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGR1 | early growth response 1 | 0.288113 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.219485 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.207005 |
| GRB10 | growth factor receptor-bound protein 10 | 0.150757 |
| ZFP36 | ZFP36 ring finger protein | 0.129714 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.106113 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.100724 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0997199 |
| KLF10 | Kruppel-like factor 10 | 0.0967427 |
| JUN | jun proto-oncogene | 0.0966457 |
| VIM | vimentin | 0.0962943 |
| VGF | VGF nerve growth factor inducible | 0.0885072 |
| SQSTM1 | sequestosome 1 | 0.0848178 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0842329 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0830225 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0816046 |
| B2M | beta-2-microglobulin | 0.0743005 |
| TXNIP | thioredoxin interacting protein | 0.0687051 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0684199 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0646491 |
| RIGI | RNA sensor RIG-I | 0.062387 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0610147 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0598384 |
| PTMA | prothymosin, alpha | 0.0587259 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0585832 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0562618 |
| H3-3B | H3.3 histone B | 0.0554743 |
| FOSL1 | FOS-like antigen 1 | 0.0547807 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0533462 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0531848 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0529209 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0520182 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0519398 |
| FN1 | fibronectin 1 | 0.0512196 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0495917 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0483319 |
| IER2 | immediate early response 2 | 0.0455765 |
| RPLP1 | ribosomal protein, large, P1 | 0.0455352 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0430623 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0427286 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0405054 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0397869 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0387319 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.038565 |
| YBX1 | Y box binding protein 1 | 0.0370246 |
| CENPF | centromere protein F, 350/400kDa | 0.0370084 |
| HMGB2 | high mobility group box 2 | 0.036284 |
| KRT17 | keratin 17, type I | 0.0360238 |
| ARRDC4 | arrestin domain containing 4 | 0.0355743 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0355237 |
| PLK2 | polo-like kinase 2 | 0.0354157 |
| SETX | senataxin | 0.034866 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0343616 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.033981 |
| DENND4A | DENN/MADD domain containing 4A | 0.0338859 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0335446 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0334446 |
| OGA | O-GlcNAcase | 0.0331776 |
| SSH2 | slingshot protein phosphatase 2 | 0.0329817 |
| BRD4 | bromodomain containing 4 | 0.0328297 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0324291 |
| SON | SON DNA binding protein | 0.0316569 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.031571 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0313162 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0311194 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0309625 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0308016 |
| SPAG9 | sperm associated antigen 9 | 0.0304979 |
| PGK1 | phosphoglycerate kinase 1 | 0.0299579 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0299164 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0295865 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0289652 |
| LAMB3 | laminin, beta 3 | 0.0289416 |
| HLA-A | major histocompatibility complex, class I, A | 0.0280868 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.028003 |
| TMSB10 | thymosin beta 10 | 0.027744 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0275016 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0273814 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0271389 |
| IER3 | immediate early response 3 | 0.0270311 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0269116 |
| BRD2 | bromodomain containing 2 | 0.026818 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0266932 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.0265851 |
| SRPK2 | SRSF protein kinase 2 | 0.0263973 |
| RPLP2 | ribosomal protein, large, P2 | 0.0256672 |
| CALR | calreticulin | 0.0256438 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0255579 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.0255548 |
| STAG2 | stromal antigen 2 | 0.0254316 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0253138 |
| RBM25 | RNA binding motif protein 25 | 0.0249931 |
| TMEM87A | transmembrane protein 87A | 0.0247784 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0247048 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0246689 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0245157 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0240808 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0239857 |
| GPR137B | G protein-coupled receptor 137B | 0.0236058 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0235222 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0701843 |
| MYO1E | myosin IE | -0.061623 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0592864 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0554381 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0545775 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0532754 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0527552 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0514063 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0486304 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0463137 |
| LMO7 | LIM domain 7 | -0.0446605 |
| MSI2 | musashi RNA-binding protein 2 | -0.04352 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0434231 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0428607 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0425287 |
| NF1 | neurofibromin 1 | -0.0409943 |
| FNIP1 | folliculin interacting protein 1 | -0.0403706 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0401518 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.039809 |
| CERS6 | ceramide synthase 6 | -0.039726 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0388529 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0385607 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0384355 |
| USP53 | ubiquitin specific peptidase 53 | -0.0381033 |
| SETD2 | SET domain containing 2 | -0.0379139 |
| ANXA2 | annexin A2 | -0.037578 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0369778 |
| PTK2 | protein tyrosine kinase 2 | -0.0367778 |
| GPC6 | glypican 6 | -0.036553 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0361022 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0360271 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0357717 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0352479 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0345461 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0345219 |
| PAPOLA | poly(A) polymerase alpha | -0.0344418 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0341606 |
| YBX3 | Y box binding protein 3 | -0.0339563 |
| RUNX1 | runt-related transcription factor 1 | -0.0333988 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.032755 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.032736 |
| RORA | RAR-related orphan receptor A | -0.0324012 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0321424 |
| CTTN | cortactin | -0.0318763 |
| RPS14 | ribosomal protein S14 | -0.0318642 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0318586 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0317213 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0317046 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0316205 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.031374 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0311675 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0311582 |
| SMYD3 | SET and MYND domain containing 3 | -0.0311152 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0309399 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0307604 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.030707 |
| RAD51B | RAD51 paralog B | -0.030648 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0303288 |
| CYTH1 | cytohesin 1 | -0.0300098 |
| OSMR | oncostatin M receptor | -0.0298835 |
| ENAH | enabled homolog (Drosophila) | -0.0297599 |
| ACTN1 | actinin, alpha 1 | -0.0295063 |
| GDI2 | GDP dissociation inhibitor 2 | -0.0293767 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0291676 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0288905 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0288837 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0288479 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0288239 |
| VMP1 | vacuole membrane protein 1 | -0.0287835 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0287368 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0287136 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0286477 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0284231 |
| PTGES2 | prostaglandin E synthase 2 | -0.028308 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0283062 |
| COG5 | component of oligomeric golgi complex 5 | -0.0283036 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.028286 |
| NRG1 | neuregulin 1 | -0.0282353 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0280869 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0280704 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0280065 |
| FTO | fat mass and obesity associated | -0.0279407 |
| SLMAP | sarcolemma associated protein | -0.0279191 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0279064 |
| COPA | coatomer protein complex, subunit alpha | -0.0276065 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | -0.0276022 |
| OXSR1 | oxidative stress responsive 1 | -0.0275781 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0275163 |
| S100A10 | S100 calcium binding protein A10 | -0.0273477 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0272547 |
| MAP1B | microtubule-associated protein 1B | -0.0272027 |
| GOLGB1 | golgin B1 | -0.0272014 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0270521 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0269547 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0268893 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0267175 |
| GPATCH2L | G patch domain containing 2-like | -0.0266801 |
| BPTF | bromodomain PHD finger transcription factor | -0.026651 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0266171 |
| FAT1 | FAT atypical cadherin 1 | -0.0260615 |
