| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Harringtonine perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Harringtonine_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.179815 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.107922 |
| SQSTM1 | sequestosome 1 | 0.0964283 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0948849 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0879515 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0868573 |
| B3GALNT2 | beta-1,3-N-acetylgalactosaminyltransferase 2 | 0.0848383 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0845993 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0761214 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0755404 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0720223 |
| CCDC6 | coiled-coil domain containing 6 | 0.0719916 |
| FTL | ferritin, light polypeptide | 0.0716761 |
| SPAG9 | sperm associated antigen 9 | 0.0689718 |
| RGS2 | regulator of G-protein signaling 2 | 0.0685821 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | 0.0663034 |
| RPL37A | ribosomal protein L37a | 0.0647372 |
| B2M | beta-2-microglobulin | 0.0625252 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0616293 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0599746 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0594335 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0570682 |
| MT2A | metallothionein 2A | 0.0546233 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0538659 |
| PGK1 | phosphoglycerate kinase 1 | 0.0525967 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0502627 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0498724 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0489701 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0489466 |
| RIGI | RNA sensor RIG-I | 0.0483305 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0475924 |
| PTMA | prothymosin, alpha | 0.0474419 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0471708 |
| RPS6 | ribosomal protein S6 | 0.0464655 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0461319 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0456433 |
| CD83 | CD83 molecule | 0.0455492 |
| RYR2 | ryanodine receptor 2 (cardiac) | 0.0453353 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0444751 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0442207 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0435335 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0432319 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0428649 |
| PER1 | period circadian clock 1 | 0.0410922 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0407929 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0397363 |
| RPS19 | ribosomal protein S19 | 0.0396452 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0391894 |
| HEATR1 | HEAT repeat containing 1 | 0.039185 |
| ZFP36 | ZFP36 ring finger protein | 0.0391321 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0388132 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0387122 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0387084 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0384944 |
| RPL36 | ribosomal protein L36 | 0.0380505 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0377393 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0373695 |
| NID1 | nidogen 1 | 0.0371842 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | 0.0369645 |
| KLF10 | Kruppel-like factor 10 | 0.0367853 |
| TMSB10 | thymosin beta 10 | 0.0359637 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0358266 |
| RPL26 | ribosomal protein L26 | 0.0357921 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.035511 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0355052 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.035502 |
| RPL31 | ribosomal protein L31 | 0.0349801 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0349325 |
| RPLP1 | ribosomal protein, large, P1 | 0.0340844 |
| RPL19 | ribosomal protein L19 | 0.032926 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0317606 |
| RPS3 | ribosomal protein S3 | 0.0315411 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 | 0.0309158 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0308491 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0303975 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0302631 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.029874 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0297673 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0296284 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0294438 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0288402 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0288368 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0287261 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0284457 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.028443 |
| EGR4 | early growth response 4 | 0.0283686 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0282358 |
| USP36 | ubiquitin specific peptidase 36 | 0.0280464 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.0280077 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0279167 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0278753 |
| RPL23 | ribosomal protein L23 | 0.0277655 |
| DENND4A | DENN/MADD domain containing 4A | 0.027566 |
| OGA | O-GlcNAcase | 0.0275344 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0269903 |
| SAR1A | secretion associated, Ras related GTPase 1A | 0.0269661 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.026947 |
| GNAS | GNAS complex locus | 0.0269103 |
| RPL35 | ribosomal protein L35 | 0.0268929 |
| YBX3 | Y box binding protein 3 | 0.0265623 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.119786 |
| EFNA5 | ephrin-A5 | -0.0935156 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0848669 |
| GDA | guanine deaminase | -0.0795983 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0611278 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0596751 |
| EGR1 | early growth response 1 | -0.0570688 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0557329 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0527922 |
| INHBA | inhibin, beta A | -0.0522436 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0471225 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0466699 |
| PLCB4 | phospholipase C, beta 4 | -0.0461175 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0457915 |
| ASPH | aspartate beta-hydroxylase | -0.0457744 |
| GRAMD1B | GRAM domain containing 1B | -0.0457277 |
| FLNB | filamin B, beta | -0.0439899 |
| CD44 | CD44 molecule (Indian blood group) | -0.0437236 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0432944 |
| RTN4 | reticulon 4 | -0.0425309 |
| CDH13 | cadherin 13 | -0.0411441 |
| AUTS2 | autism susceptibility candidate 2 | -0.0407579 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0401555 |
| TXNRD1 | thioredoxin reductase 1 | -0.039575 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0387785 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0370283 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0365731 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.036556 |
| COL4A6 | collagen, type IV, alpha 6 | -0.0362351 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0353545 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0325435 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0320659 |
| NBAS | neuroblastoma amplified sequence | -0.031504 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0304841 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0303498 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0295424 |
| ATXN1 | ataxin 1 | -0.0293794 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.029296 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0290208 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0288539 |
| COG5 | component of oligomeric golgi complex 5 | -0.0285597 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.028523 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0283863 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0282519 |
| FAT1 | FAT atypical cadherin 1 | -0.0280722 |
| RASAL2 | RAS protein activator like 2 | -0.0280495 |
| DNER | delta/notch-like EGF repeat containing | -0.0278132 |
| LDHA | lactate dehydrogenase A | -0.0277673 |
| SOCS3 | suppressor of cytokine signaling 3 | -0.0275042 |
| CD109 | CD109 molecule | -0.0274563 |
| VIM | vimentin | -0.0271169 |
| RUNX1 | runt-related transcription factor 1 | -0.0270712 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0268129 |
| MYO10 | myosin X | -0.0266802 |
| KYNU | kynureninase | -0.0264395 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0264045 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.025976 |
| JMJD1C | jumonji domain containing 1C | -0.025902 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0257793 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0257038 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0253313 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0250874 |
| COPA | coatomer protein complex, subunit alpha | -0.0248669 |
| SLC38A2 | solute carrier family 38, member 2 | -0.024321 |
| PCBP2 | poly(rC) binding protein 2 | -0.0241966 |
| NDRG1 | N-myc downstream regulated 1 | -0.0238788 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0227737 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0227178 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.022667 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0226646 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0223523 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0219185 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0218568 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0218428 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0216708 |
| BMERB1 | bMERB domain containing 1 | -0.0215208 |
| LAMA5 | laminin, alpha 5 | -0.0214011 |
| CALU | calumenin | -0.0210053 |
| SNX9 | sorting nexin 9 | -0.0209609 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0208517 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0205247 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0205164 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0204238 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0203467 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0203333 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0202284 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0201195 |
| IER3 | immediate early response 3 | -0.0200995 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0199493 |
| USP34 | ubiquitin specific peptidase 34 | -0.0197771 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0197204 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0194119 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0191714 |
| GPC6 | glypican 6 | -0.0191395 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0191334 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.019036 |
| TUT7 | terminal uridylyl transferase 7 | -0.0189825 |
| VMP1 | vacuole membrane protein 1 | -0.0188805 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0187832 |
| EXOC4 | exocyst complex component 4 | -0.0187754 |
