| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Harringtonine perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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115 genes differentially expressed following the Harringtonine_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.185327 |
| SLTM | SAFB-like, transcription modulator | 0.162439 |
| EGFR | epidermal growth factor receptor | 0.160171 |
| PER1 | period circadian clock 1 | 0.122503 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.121601 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.12107 |
| GRAMD1B | GRAM domain containing 1B | 0.1194 |
| USP3 | ubiquitin specific peptidase 3 | 0.108055 |
| PDE10A | phosphodiesterase 10A | 0.106356 |
| ATF4 | activating transcription factor 4 | 0.103956 |
| MT2A | metallothionein 2A | 0.102588 |
| RTN4 | reticulon 4 | 0.100443 |
| TXNRD1 | thioredoxin reductase 1 | 0.0888443 |
| EZR | ezrin | 0.0867319 |
| RPL11 | ribosomal protein L11 | 0.079974 |
| NUP58 | nucleoporin 58 | 0.0789288 |
| TOP1 | topoisomerase (DNA) I | 0.0780253 |
| MED13L | mediator complex subunit 13-like | 0.0754758 |
| SDC4 | syndecan 4 | 0.0740099 |
| RPL37A | ribosomal protein L37a | 0.0739155 |
| PGK1 | phosphoglycerate kinase 1 | 0.0727515 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.061705 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.056626 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0534981 |
| ZNF292 | zinc finger protein 292 | 0.0497832 |
| EGR1 | early growth response 1 | 0.0496702 |
| ANXA2 | annexin A2 | 0.0474637 |
| PRRC2C | proline-rich coiled-coil 2C | 0.046632 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0458591 |
| RPS6 | ribosomal protein S6 | 0.0447181 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0407973 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0387095 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0367844 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.036099 |
| APP | amyloid beta (A4) precursor protein | 0.0334022 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0315026 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0314998 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0296173 |
| POTEF | POTE ankyrin domain family, member F | 0.0292471 |
| AOPEP | aminopeptidase O (putative) | 0.0284896 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0284349 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0273569 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0242113 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0234543 |
| RIGI | RNA sensor RIG-I | 0.0211894 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0184997 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0174191 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0170014 |
| TMSB10 | thymosin beta 10 | 0.0119442 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0111662 |
| BBX | bobby sox homolog (Drosophila) | 0.00602899 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.00512315 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.00467746 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.00458364 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.00417779 |
| ANKRD17 | ankyrin repeat domain 17 | 0.00360576 |
| SETD5 | SET domain containing 5 | 0.00272002 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.00157415 |
| SPAG9 | sperm associated antigen 9 | 0.00132404 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 2.64937E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.223201 |
| FN1 | fibronectin 1 | -0.205649 |
| EXT1 | exostosin glycosyltransferase 1 | -0.145103 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.14165 |
| NDRG1 | N-myc downstream regulated 1 | -0.138527 |
| CD44 | CD44 molecule (Indian blood group) | -0.127794 |
| JMJD1C | jumonji domain containing 1C | -0.120494 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.116273 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.107036 |
| MYO10 | myosin X | -0.0899379 |
| GOLGA4 | golgin A4 | -0.0806811 |
| ATP13A3 | ATPase type 13A3 | -0.0775418 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0766077 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0738172 |
| RBM39 | RNA binding motif protein 39 | -0.0736194 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0718914 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0718344 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0673581 |
| ASPH | aspartate beta-hydroxylase | -0.0614431 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.061402 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0526413 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0496922 |
| MCL1 | myeloid cell leukemia 1 | -0.04805 |
| JUN | jun proto-oncogene | -0.0438468 |
| PARD3 | par-3 family cell polarity regulator | -0.0434324 |
| SQSTM1 | sequestosome 1 | -0.0362674 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0354183 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0344082 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0338522 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0333463 |
| KLF10 | Kruppel-like factor 10 | -0.0310761 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0308694 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0300773 |
| STC1 | stanniocalcin 1 | -0.029653 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0220418 |
| PTMA | prothymosin, alpha | -0.021837 |
| B2M | beta-2-microglobulin | -0.0218339 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0210279 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.020719 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0206342 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0196421 |
| SRPK2 | SRSF protein kinase 2 | -0.018985 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0176251 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0133253 |
| FOSL1 | FOS-like antigen 1 | -0.012365 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0108449 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.00970611 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00810196 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.00634703 |
| TCF12 | transcription factor 12 | -0.00562125 |
| LDHA | lactate dehydrogenase A | -0.00413379 |
| CDH13 | cadherin 13 | -0.00405612 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.00384697 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00170112 |
| DOCK4 | dedicator of cytokinesis 4 | -4.32495E-4 |
