| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Harringtonine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Harringtonine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.112328 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.111565 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0939302 |
| CENPF | centromere protein F, 350/400kDa | 0.0920118 |
| KLF10 | Kruppel-like factor 10 | 0.0879937 |
| ZNF217 | zinc finger protein 217 | 0.0857227 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0850858 |
| SETD5 | SET domain containing 5 | 0.0702982 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0616475 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0594745 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0594654 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0571082 |
| H1-0 | H1.0 linker histone | 0.0564925 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0549159 |
| PRRC2C | proline-rich coiled-coil 2C | 0.052927 |
| PLK2 | polo-like kinase 2 | 0.0524105 |
| MKI67 | marker of proliferation Ki-67 | 0.0514915 |
| OGA | O-GlcNAcase | 0.0504733 |
| BRD2 | bromodomain containing 2 | 0.0491158 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0461081 |
| MED13L | mediator complex subunit 13-like | 0.0460123 |
| TMSB10 | thymosin beta 10 | 0.0458598 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0450865 |
| COL3A1 | collagen, type III, alpha 1 | 0.0450847 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0448379 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.044675 |
| CCDC88A | coiled-coil domain containing 88A | 0.0444889 |
| COL5A2 | collagen, type V, alpha 2 | 0.0440724 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.043951 |
| SQSTM1 | sequestosome 1 | 0.0437999 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0437746 |
| ECT2 | epithelial cell transforming 2 | 0.0424162 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0420956 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.041895 |
| ARL13B | ADP-ribosylation factor-like 13B | 0.0418513 |
| EGR1 | early growth response 1 | 0.0417105 |
| PDS5B | PDS5 cohesin associated factor B | 0.0410991 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0407068 |
| TPR | translocated promoter region, nuclear basket protein | 0.0404275 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0399021 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0399015 |
| DST | dystonin | 0.039837 |
| B2M | beta-2-microglobulin | 0.0398083 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0397971 |
| FAM171B | family with sequence similarity 171, member B | 0.0393189 |
| RYBP | RING1 and YY1 binding protein | 0.0386739 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0383358 |
| PHIP | pleckstrin homology domain interacting protein | 0.0379603 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0362988 |
| ARRDC3 | arrestin domain containing 3 | 0.0362691 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0362506 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0362014 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0360111 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0359536 |
| ITGAV | integrin, alpha V | 0.0355237 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0354775 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0354293 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0353297 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0350778 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.034967 |
| JUN | jun proto-oncogene | 0.0349586 |
| RANBP2 | RAN binding protein 2 | 0.0348298 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0345642 |
| UVRAG | UV radiation resistance associated | 0.0338828 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0338171 |
| BNC2 | basonuclin 2 | 0.0337181 |
| ZFP36 | ZFP36 ring finger protein | 0.0335883 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0333155 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0331641 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0329462 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0329386 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0327003 |
| IL6ST | interleukin 6 signal transducer | 0.0325506 |
| HMCN1 | hemicentin 1 | 0.0325008 |
| PTMA | prothymosin, alpha | 0.0324123 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0317386 |
| THOC2 | THO complex 2 | 0.0316691 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0313928 |
| CKAP2 | cytoskeleton associated protein 2 | 0.031124 |
| RSF1 | remodeling and spacing factor 1 | 0.0307754 |
| GOLGB1 | golgin B1 | 0.0302491 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.02994 |
| COL1A2 | collagen, type I, alpha 2 | 0.029716 |
| DENND4A | DENN/MADD domain containing 4A | 0.0296374 |
| FNDC3A | fibronectin type III domain containing 3A | 0.029524 |
| TPX2 | TPX2, microtubule-associated | 0.0289996 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0289617 |
| KIF4A | kinesin family member 4A | 0.028432 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0281531 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0280892 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0280514 |
| SYT1 | synaptotagmin I | 0.0278776 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0272246 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.0271081 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0271032 |
| NUP153 | nucleoporin 153kDa | 0.0270127 |
| FIGN | fidgetin | 0.0269444 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0269081 |
| RPL31 | ribosomal protein L31 | 0.0267979 |
| SETD2 | SET domain containing 2 | 0.0267271 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.108723 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.101791 |
| ZNF292 | zinc finger protein 292 | -0.0970184 |
| THBS1 | thrombospondin 1 | -0.0814617 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0751972 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.065544 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0610222 |
| GPC3 | glypican 3 | -0.0544942 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0541648 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0524716 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0437741 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0436328 |
| SMYD3 | SET and MYND domain containing 3 | -0.0435705 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.043464 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0427906 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0397029 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.038557 |
| ANK2 | ankyrin 2, neuronal | -0.037841 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0370837 |
| MAP4 | microtubule-associated protein 4 | -0.033747 |
| AHNAK | AHNAK nucleoprotein | -0.0333182 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0327422 |
| RLF | rearranged L-myc fusion | -0.0325403 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0320929 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0317614 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0316888 |
| FOXP2 | forkhead box P2 | -0.031421 |
| ACTG1 | actin gamma 1 | -0.0310553 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0308781 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0303704 |
| HMGA2 | high mobility group AT-hook 2 | -0.0301976 |
| URI1 | URI1, prefoldin-like chaperone | -0.0296838 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0293584 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0292813 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0288686 |
| PTK2 | protein tyrosine kinase 2 | -0.0286725 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0281985 |
| TENM3 | teneurin transmembrane protein 3 | -0.0281755 |
| TPM3 | tropomyosin 3 | -0.0280657 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0279021 |
| ANXA2 | annexin A2 | -0.0274393 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | -0.026923 |
| CTBP2 | C-terminal binding protein 2 | -0.0267062 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0265894 |
| PDS5A | PDS5 cohesin associated factor A | -0.0260638 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.025438 |
| WDR43 | WD repeat domain 43 | -0.0253713 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0251467 |
| CLTC | clathrin, heavy chain (Hc) | -0.0251366 |
| LDHA | lactate dehydrogenase A | -0.0246858 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0238814 |
| MEIS2 | Meis homeobox 2 | -0.0237004 |
| FLNB | filamin B, beta | -0.0236802 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0230036 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0229544 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0228291 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0228122 |
| TENM2 | teneurin transmembrane protein 2 | -0.0227568 |
| UBE3C | ubiquitin protein ligase E3C | -0.022556 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0224756 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0223197 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0219833 |
| CCN2 | cellular communication network factor 2 | -0.0219297 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0218576 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0217239 |
| ILRUN | inflammation and lipid regulator with UBA-like and NBR1-like domains | -0.0215214 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0214515 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0211224 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0210743 |
| GRB2 | growth factor receptor-bound protein 2 | -0.0209623 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0209079 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0208446 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0208194 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0207987 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0206726 |
| IPO7 | importin 7 | -0.0206217 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0204735 |
| PARD3 | par-3 family cell polarity regulator | -0.0204598 |
| SRPK2 | SRSF protein kinase 2 | -0.0204171 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0203805 |
| VMP1 | vacuole membrane protein 1 | -0.0203558 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0203535 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.02028 |
| KIAA1328 | KIAA1328 | -0.0200125 |
| DSTN | destrin (actin depolymerizing factor) | -0.0199324 |
| HMGB1 | high mobility group box 1 | -0.0199166 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | -0.0197399 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0197224 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0195994 |
| SRP54 | signal recognition particle 54kDa | -0.0195879 |
| TXNRD1 | thioredoxin reductase 1 | -0.0194761 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0192789 |
| CDC73 | cell division cycle 73 | -0.0187793 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0187613 |
| RHOA | ras homolog family member A | -0.0187339 |
| RBBP7 | retinoblastoma binding protein 7 | -0.0185606 |
| SET | SET nuclear proto-oncogene | -0.0185538 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.01854 |
| RREB1 | ras responsive element binding protein 1 | -0.0184881 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0184753 |
