| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Harringtonine perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Harringtonine_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EZR | ezrin | 0.0534867 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.048484 |
| ZNF292 | zinc finger protein 292 | 0.0313794 |
| LDHA | lactate dehydrogenase A | 0.0273224 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0256596 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0247171 |
| NUP58 | nucleoporin 58 | 0.0241222 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0238694 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0234997 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0220217 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0215828 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0209611 |
| PLK2 | polo-like kinase 2 | 0.0209172 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0201598 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0199099 |
| FLNB | filamin B, beta | 0.0197734 |
| WDR45B | WD repeat domain 45B | 0.0186931 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0178465 |
| TXNIP | thioredoxin interacting protein | 0.0173072 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0172356 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0172275 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0172173 |
| WDR43 | WD repeat domain 43 | 0.0170494 |
| S100A11 | S100 calcium binding protein A11 | 0.0169444 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0168391 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0167458 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0163675 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0162457 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0159605 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | 0.0150363 |
| CABIN1 | calcineurin binding protein 1 | 0.0149133 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0145263 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0144917 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0143463 |
| CASC3 | cancer susceptibility candidate 3 | 0.0141808 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0136721 |
| RBM25 | RNA binding motif protein 25 | 0.0136186 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0136163 |
| ANXA2 | annexin A2 | 0.0136102 |
| RTN4 | reticulon 4 | 0.0132612 |
| INSIG2 | insulin induced gene 2 | 0.0132141 |
| ARRDC3 | arrestin domain containing 3 | 0.0130473 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0126249 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0124728 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0122281 |
| DUSP4 | dual specificity phosphatase 4 | 0.0121229 |
| CDV3 | CDV3 homolog (mouse) | 0.0120807 |
| DENR | density-regulated protein | 0.0120504 |
| ZNF160 | zinc finger protein 160 | 0.0119218 |
| HMGB2 | high mobility group box 2 | 0.0113749 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.011266 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0111887 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0106948 |
| SRP19 | signal recognition particle 19kDa | 0.0106852 |
| COG6 | component of oligomeric golgi complex 6 | 0.0106258 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0106018 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0105449 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0104033 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0103678 |
| FLNA | filamin A, alpha | 0.0103274 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0102863 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0102522 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0101648 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0101444 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0101256 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0101002 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0100961 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.00996834 |
| ZNF217 | zinc finger protein 217 | 0.00985089 |
| GATA6 | GATA binding protein 6 | 0.00982943 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0097501 |
| SUCO | SUN domain containing ossification factor | 0.00970128 |
| ARF4 | ADP-ribosylation factor 4 | 0.0094557 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.00945249 |
| MT2A | metallothionein 2A | 0.009445 |
| GLMN | glomulin, FKBP associated protein | 0.00943939 |
| DIPK2A | divergent protein kinase domain 2A | 0.00942072 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.00936413 |
| RUNX1 | runt-related transcription factor 1 | 0.00931219 |
| CTNNBL1 | catenin, beta like 1 | 0.00929475 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00928205 |
| RYBP | RING1 and YY1 binding protein | 0.00908757 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.00902679 |
| TSNAX | translin-associated factor X | 0.00902283 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.00890917 |
| HELZ | helicase with zinc finger | 0.00879743 |
| THOC1 | THO complex 1 | 0.00875391 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.00874023 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.00863021 |
| UFM1 | ubiquitin-fold modifier 1 | 0.0086294 |
| CCNK | cyclin K | 0.0084539 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.00838817 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.00833355 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0083307 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide | 0.00830142 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.00825625 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.00822024 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00821985 |
| TMEM39A | transmembrane protein 39A | 0.00817438 |
| LEO1 | Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.00817305 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.180079 |
| VCL | vinculin | -0.167176 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.165775 |
| PTMA | prothymosin, alpha | -0.155009 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.14558 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.133212 |
| FOXP1 | forkhead box P1 | -0.125084 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.123494 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.121458 |
| NBEA | neurobeachin | -0.0970804 |
| BMP10 | bone morphogenetic protein 10 | -0.0911153 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0829045 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0782492 |
| HDAC9 | histone deacetylase 9 | -0.075423 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0751119 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0736881 |
| EGR1 | early growth response 1 | -0.0733741 |
| PKM | pyruvate kinase, muscle | -0.0713854 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0648586 |
| EGFR | epidermal growth factor receptor | -0.0611889 |
| GLI3 | GLI family zinc finger 3 | -0.0606713 |
| TJP1 | tight junction protein 1 | -0.0597767 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0593173 |
| EFNA5 | ephrin-A5 | -0.0584939 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0578548 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0574458 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0571143 |
| CCND1 | cyclin D1 | -0.056987 |
| TMSB4X | thymosin beta 4, X-linked | -0.0567244 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0540209 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0529143 |
| MKI67 | marker of proliferation Ki-67 | -0.0527769 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0525247 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0517245 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0497353 |
| RPS6 | ribosomal protein S6 | -0.0491926 |
| TXNRD1 | thioredoxin reductase 1 | -0.0485007 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0482044 |
| AHNAK | AHNAK nucleoprotein | -0.047246 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0465217 |
| NFIA | nuclear factor I/A | -0.0462672 |
| ACTG1 | actin gamma 1 | -0.0462299 |
| GLI2 | GLI family zinc finger 2 | -0.0438245 |
| RPL35A | ribosomal protein L35a | -0.0427662 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0423713 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0410405 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0408575 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0398076 |
| GPHN | gephyrin | -0.0397689 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0396863 |
| RPS8 | ribosomal protein S8 | -0.0386724 |
| RPL34 | ribosomal protein L34 | -0.0364158 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0359987 |
| MYO5C | myosin VC | -0.0358245 |
| TCF12 | transcription factor 12 | -0.0355521 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0350318 |
| CUX1 | cut-like homeobox 1 | -0.0349719 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0348473 |
| S100A4 | S100 calcium binding protein A4 | -0.0342415 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0341402 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.034087 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0336992 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0336886 |
| PYGB | phosphorylase, glycogen; brain | -0.0335595 |
| ZNF438 | zinc finger protein 438 | -0.0334822 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0331792 |
| NF1 | neurofibromin 1 | -0.0329631 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0328484 |
| MAP4 | microtubule-associated protein 4 | -0.0327659 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0327051 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0322092 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.032097 |
| RHOA | ras homolog family member A | -0.0318735 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0317193 |
| TPM4 | tropomyosin 4 | -0.0306933 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0303326 |
| DIAPH3 | diaphanous-related formin 3 | -0.0300136 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0299325 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0297565 |
| EXOC6B | exocyst complex component 6B | -0.0297533 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.029552 |
| KIF5B | kinesin family member 5B | -0.029445 |
| PDE7B | phosphodiesterase 7B | -0.0293862 |
| DGKH | diacylglycerol kinase, eta | -0.029227 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.028931 |
| LOXL3 | lysyl oxidase-like 3 | -0.0286952 |
| DOCK3 | dedicator of cytokinesis 3 | -0.028688 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0286593 |
| SMYD3 | SET and MYND domain containing 3 | -0.0286354 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.02843 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0281204 |
| NAV2 | neuron navigator 2 | -0.0279853 |
| BMP2K | BMP2 inducible kinase | -0.0279691 |
| B2M | beta-2-microglobulin | -0.0277932 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0276842 |
| RPLP1 | ribosomal protein, large, P1 | -0.0275499 |
| ANXA1 | annexin A1 | -0.0272102 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.027161 |
| RPLP0 | ribosomal protein, large, P0 | -0.0271296 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.027105 |
