| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Harringtonine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Harringtonine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0915878 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0441925 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0424133 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0393177 |
| RPS3 | ribosomal protein S3 | 0.0378786 |
| RPS12 | ribosomal protein S12 | 0.0371391 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0350036 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0349507 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0328726 |
| TMSB10 | thymosin beta 10 | 0.0326326 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0302243 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0299877 |
| OGA | O-GlcNAcase | 0.0294967 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0285506 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0283877 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0275853 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0267929 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.024916 |
| RPL23 | ribosomal protein L23 | 0.0248337 |
| PCBP2 | poly(rC) binding protein 2 | 0.0243655 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0242239 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0235306 |
| RPS27A | ribosomal protein S27a | 0.0234908 |
| ANXA2 | annexin A2 | 0.0229346 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0226394 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.021696 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0209336 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0204902 |
| RPS4X | ribosomal protein S4, X-linked | 0.0201467 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0196062 |
| FLNA | filamin A, alpha | 0.0188234 |
| MKI67 | marker of proliferation Ki-67 | 0.0182102 |
| ARRDC3 | arrestin domain containing 3 | 0.0178723 |
| MT2A | metallothionein 2A | 0.0178268 |
| RTN4 | reticulon 4 | 0.0172655 |
| HMGB2 | high mobility group box 2 | 0.0160807 |
| RPL18 | ribosomal protein L18 | 0.0159324 |
| SET | SET nuclear proto-oncogene | 0.0156112 |
| ANLN | anillin, actin binding protein | 0.0151007 |
| RPS17 | ribosomal protein S17 | 0.0150438 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0150025 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0142664 |
| RACK1 | receptor for activated C kinase 1 | 0.0140352 |
| TPM3 | tropomyosin 3 | 0.0140334 |
| APP | amyloid beta (A4) precursor protein | 0.0139565 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0137027 |
| NAV2 | neuron navigator 2 | 0.0136577 |
| THBS1 | thrombospondin 1 | 0.0136149 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0135331 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0132795 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0132665 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0126256 |
| EZR | ezrin | 0.012481 |
| YBX1 | Y box binding protein 1 | 0.0123193 |
| RPL7 | ribosomal protein L7 | 0.0122279 |
| RPL35 | ribosomal protein L35 | 0.0119965 |
| DUSP5 | dual specificity phosphatase 5 | 0.0119716 |
| MLPH | melanophilin | 0.0119377 |
| CENPF | centromere protein F, 350/400kDa | 0.0119052 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.011745 |
| SERINC1 | serine incorporator 1 | 0.01169 |
| ZNF292 | zinc finger protein 292 | 0.011605 |
| KIF4A | kinesin family member 4A | 0.0114665 |
| DIAPH3 | diaphanous-related formin 3 | 0.0113563 |
| AFDN | afadin, adherens junction formation factor | 0.0111779 |
| TFG | TRK-fused gene | 0.0109136 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0108812 |
| DSTN | destrin (actin depolymerizing factor) | 0.0108557 |
| CCNL1 | cyclin L1 | 0.0107369 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0106839 |
| TMEM41B | transmembrane protein 41B | 0.0106745 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0106216 |
| RPL26 | ribosomal protein L26 | 0.0105586 |
| ACTN4 | actinin, alpha 4 | 0.0105279 |
| KLF6 | Kruppel-like factor 6 | 0.0104099 |
| RAI1 | retinoic acid induced 1 | 0.0103488 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0101639 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.00999657 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.00998554 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.00991856 |
| RNF145 | ring finger protein 145 | 0.00991332 |
| FTL | ferritin, light polypeptide | 0.00979001 |
| UBC | ubiquitin C | 0.00972674 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.00967206 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.00961252 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.00954791 |
| RPL12 | ribosomal protein L12 | 0.00949833 |
| SYAP1 | synapse associated protein 1 | 0.00948926 |
| CKAP2 | cytoskeleton associated protein 2 | 0.00945875 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.00941703 |
| TPX2 | TPX2, microtubule-associated | 0.00938951 |
| FOSL1 | FOS-like antigen 1 | 0.00938616 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00938416 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.00926059 |
| RPS5 | ribosomal protein S5 | 0.00923089 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.00909754 |
| SMAD3 | SMAD family member 3 | 0.00908248 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.00903028 |
| SPAG9 | sperm associated antigen 9 | 0.00897872 |
| RPS2 | ribosomal protein S2 | 0.00873259 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.10751 |
| HLA-B | major histocompatibility complex, class I, B | -0.0825351 |
| GLIS3 | GLIS family zinc finger 3 | -0.0667362 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0649462 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0647957 |
| CD44 | CD44 molecule (Indian blood group) | -0.062997 |
| DST | dystonin | -0.062625 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0580996 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0568221 |
| IER3 | immediate early response 3 | -0.0534782 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0515547 |
| CDH13 | cadherin 13 | -0.0505802 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0487117 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0441195 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0439017 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0408623 |
| FRMD4A | FERM domain containing 4A | -0.040719 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0400549 |
| HMGA2 | high mobility group AT-hook 2 | -0.0393564 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0391592 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0378545 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0377318 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0374359 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0356726 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0335356 |
| CTSD | cathepsin D | -0.0329104 |
| DIAPH2 | diaphanous-related formin 2 | -0.0327408 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0326798 |
| RND3 | Rho family GTPase 3 | -0.0322694 |
| PLIN2 | perilipin 2 | -0.031981 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0311465 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.029648 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0294293 |
| SQSTM1 | sequestosome 1 | -0.0292386 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0288866 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0287773 |
| HLA-A | major histocompatibility complex, class I, A | -0.028333 |
| EGFR | epidermal growth factor receptor | -0.0283273 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0280969 |
| HDAC9 | histone deacetylase 9 | -0.0276724 |
| NDRG1 | N-myc downstream regulated 1 | -0.0274281 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0271414 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.026017 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.025439 |
| ADM | adrenomedullin | -0.0250834 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0249093 |
| HLA-E | major histocompatibility complex, class I, E | -0.0242575 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0242106 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0240533 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0237169 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0234656 |
| INHBA | inhibin, beta A | -0.0233383 |
| VCL | vinculin | -0.0228261 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0226076 |
| TMEM132D | transmembrane protein 132D | -0.0222423 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0221581 |
| CLMP | CXADR-like membrane protein | -0.0220073 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0219834 |
| BICC1 | BicC family RNA binding protein 1 | -0.0219195 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.0217752 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0214901 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0213727 |
| INTS6 | integrator complex subunit 6 | -0.0213038 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.020953 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0208928 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0208809 |
| BNC2 | basonuclin 2 | -0.0208069 |
| RPL35A | ribosomal protein L35a | -0.0204007 |
| PTK2 | protein tyrosine kinase 2 | -0.0203949 |
| VEGFA | vascular endothelial growth factor A | -0.0203905 |
| RAI14 | retinoic acid induced 14 | -0.0200664 |
| MAP4 | microtubule-associated protein 4 | -0.0199678 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0198283 |
| KYNU | kynureninase | -0.0196716 |
| ERBIN | erbb2 interacting protein | -0.0195408 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0193969 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0193056 |
| RNF213 | ring finger protein 213 | -0.0192753 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0189852 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0188383 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | -0.0188217 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0187232 |
| EFNA5 | ephrin-A5 | -0.0184898 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0184301 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0184069 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0183844 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0181685 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.018086 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0178703 |
| IL6ST | interleukin 6 signal transducer | -0.0178476 |
| RAD51B | RAD51 paralog B | -0.0176982 |
| SP100 | SP100 nuclear antigen | -0.0175022 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0174773 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.017465 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0174477 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.017416 |
| TXNIP | thioredoxin interacting protein | -0.0173218 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0170861 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0169468 |
| PDE10A | phosphodiesterase 10A | -0.0169386 |
